JP2003012516A5 - - Google Patents
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- Publication number
- JP2003012516A5 JP2003012516A5 JP2001391481A JP2001391481A JP2003012516A5 JP 2003012516 A5 JP2003012516 A5 JP 2003012516A5 JP 2001391481 A JP2001391481 A JP 2001391481A JP 2001391481 A JP2001391481 A JP 2001391481A JP 2003012516 A5 JP2003012516 A5 JP 2003012516A5
- Authority
- JP
- Japan
- Prior art keywords
- calmodulin
- calcium
- kinase inhibitor
- dependent kinase
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 6
- 102000000584 Calmodulin Human genes 0.000 claims 6
- 108010041952 Calmodulin Proteins 0.000 claims 6
- 108091000080 Phosphotransferase Proteins 0.000 claims 6
- 229910052791 calcium Inorganic materials 0.000 claims 6
- 239000011575 calcium Substances 0.000 claims 6
- 230000001419 dependent effect Effects 0.000 claims 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 6
- 229940043355 kinase inhibitor Drugs 0.000 claims 6
- 102000020233 phosphotransferase Human genes 0.000 claims 6
- 239000003757 phosphotransferase inhibitor Substances 0.000 claims 6
- 239000004480 active ingredient Substances 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- NRCNNTRSSNMMJV-UHFFFAOYSA-N benzo[de]isoquinolin-6-one Chemical class C1=CC(C(=O)C=C2)=C3C2=CN=CC3=C1 NRCNNTRSSNMMJV-UHFFFAOYSA-N 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 125000001188 haloalkyl group Chemical group 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 125000001624 naphthyl group Chemical group 0.000 claims 1
- 125000000547 substituted alkyl group Chemical group 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001391481A JP4153693B2 (ja) | 2001-04-25 | 2001-12-25 | 新規なCaMKK阻害剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001127524 | 2001-04-25 | ||
| JP2001-127524 | 2001-04-25 | ||
| JP2001391481A JP4153693B2 (ja) | 2001-04-25 | 2001-12-25 | 新規なCaMKK阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003012516A JP2003012516A (ja) | 2003-01-15 |
| JP2003012516A5 true JP2003012516A5 (OSRAM) | 2005-07-14 |
| JP4153693B2 JP4153693B2 (ja) | 2008-09-24 |
Family
ID=26614177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001391481A Expired - Fee Related JP4153693B2 (ja) | 2001-04-25 | 2001-12-25 | 新規なCaMKK阻害剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4153693B2 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8207185B2 (en) | 2006-10-12 | 2012-06-26 | Duke University | CaMKKβ as a target for treating obesity |
| US20130253035A1 (en) | 2010-08-16 | 2013-09-26 | Duke University | Camkk-beta as a target for treating cancer |
| KR20160038052A (ko) * | 2013-08-05 | 2016-04-06 | 바스프 에스이 | 시안화 나프탈렌벤즈이미다졸 화합물 |
| US12221447B2 (en) * | 2018-08-20 | 2025-02-11 | Duke University | Methods and compositions for drugs to treat ophthalmic diseases |
-
2001
- 2001-12-25 JP JP2001391481A patent/JP4153693B2/ja not_active Expired - Fee Related
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