JP2002543151A5 - - Google Patents
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- Publication number
- JP2002543151A5 JP2002543151A5 JP2000615040A JP2000615040A JP2002543151A5 JP 2002543151 A5 JP2002543151 A5 JP 2002543151A5 JP 2000615040 A JP2000615040 A JP 2000615040A JP 2000615040 A JP2000615040 A JP 2000615040A JP 2002543151 A5 JP2002543151 A5 JP 2002543151A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- polypeptide
- antibody
- composition according
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13249899P | 1999-05-04 | 1999-05-04 | |
| US60/132,498 | 1999-05-04 | ||
| US13323899P | 1999-05-07 | 1999-05-07 | |
| US60/133,238 | 1999-05-07 | ||
| US14893999P | 1999-08-13 | 1999-08-13 | |
| US60/148,939 | 1999-08-13 | ||
| PCT/US2000/012041 WO2000066156A1 (en) | 1999-05-04 | 2000-05-04 | Death domain containing receptor 5 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002543151A JP2002543151A (ja) | 2002-12-17 |
| JP2002543151A5 true JP2002543151A5 (https=) | 2007-05-31 |
Family
ID=27384298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000615040A Pending JP2002543151A (ja) | 1999-05-04 | 2000-05-04 | 死ドメイン含有レセプター５ |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1196191A4 (https=) |
| JP (1) | JP2002543151A (https=) |
| AU (1) | AU4817200A (https=) |
| CA (1) | CA2369371A1 (https=) |
| WO (1) | WO2000066156A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7528239B1 (en) | 1997-02-13 | 2009-05-05 | Immunex Corporation | Receptor that binds trail |
| US6342369B1 (en) | 1997-05-15 | 2002-01-29 | Genentech, Inc. | Apo-2-receptor |
| US7476383B2 (en) | 2000-05-02 | 2009-01-13 | The Uab Research Foundation | Antibody selective for DR4 and uses thereof |
| TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
| US7279160B2 (en) | 2000-05-02 | 2007-10-09 | The Uab Research Foundation | Combinations of DR5 antibodies and other therapeutic agents |
| AU2002256895B2 (en) * | 2001-05-18 | 2008-09-18 | Kirin Beer Kabushiki Kaisha | Anti-TRAIL-R antibodies |
| US7361341B2 (en) | 2001-05-25 | 2008-04-22 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to trail receptors |
| US7348003B2 (en) | 2001-05-25 | 2008-03-25 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors |
| MXPA03010747A (es) | 2001-05-25 | 2004-03-02 | Human Genome Sciences Inc | Anticuerpos que se unen inmunoespecificamente a receptores de ligando inductor de apoptosis relacionado con factor de necrosis tumoral. |
| EP1439225A4 (en) * | 2001-10-04 | 2005-10-26 | Kansai Tech Licensing Org Co | DR5-GEN PROMOTER AND SIAH-1-GEN PROMOTER |
| CA2520138C (en) * | 2003-03-26 | 2017-05-23 | Apogenix Gmbh | Improved fc fusion proteins |
| AU2005227322A1 (en) | 2004-03-23 | 2005-10-06 | Biogen Idec Ma Inc. | Receptor coupling agents and therapeutic uses thereof |
| WO2005114187A2 (en) * | 2004-04-23 | 2005-12-01 | The United States Of America As Represented By Thesecretary, Department Of Health And Human Services | Methods and compositions for diagnosing aids and other diseases and conditions involving immune system activation |
| KR101292961B1 (ko) | 2005-02-02 | 2013-08-02 | 더 유에이비 리서치 파운데이션 | 아폽토시스-유도 사멸 수용체 작용제에 대한 내성을 감소시키는데 관련된 약제 및 방법 |
| PE20071101A1 (es) | 2005-08-31 | 2007-12-21 | Amgen Inc | Polipeptidos y anticuerpos |
| KR20120101050A (ko) | 2009-11-05 | 2012-09-12 | 더 유에이비 리서치 파운데이션 | 기저형 유전자형 암의 치료 방법 |
| WO2011116344A2 (en) | 2010-03-18 | 2011-09-22 | The Uab Research Foundation | Targeting cancer stem cells |
| EP2831116A1 (en) * | 2012-03-28 | 2015-02-04 | Amgen Inc. | Dr5 receptor agonist combinations |
| ES2812208T3 (es) | 2013-03-14 | 2021-03-16 | Bristol Myers Squibb Co | Combinación de un agonista de DR5 y un antagonista de anti-PD-1 y métodos de uso |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010010924A1 (en) * | 1997-03-14 | 2001-08-02 | Keith Charles Deen | Tumor necrosis factor related receptor, tr6 polynecleotides |
| CN1624128A (zh) * | 1997-03-17 | 2005-06-08 | 人类基因组科学公司 | 包含死亡结构域的受体－5 |
| WO2000073349A1 (en) * | 1999-05-28 | 2000-12-07 | Genentech, Inc. | Dr4 antibodies and uses thereof |
| ATE330972T1 (de) * | 1999-06-09 | 2006-07-15 | Genentech Inc | Apo-2l rezeptor-agonist und cpt-11 synergie- effekt |
| TWI318983B (en) * | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
-
2000
- 2000-05-04 WO PCT/US2000/012041 patent/WO2000066156A1/en not_active Ceased
- 2000-05-04 EP EP00930329A patent/EP1196191A4/en not_active Withdrawn
- 2000-05-04 CA CA002369371A patent/CA2369371A1/en not_active Abandoned
- 2000-05-04 JP JP2000615040A patent/JP2002543151A/ja active Pending
- 2000-05-04 AU AU48172/00A patent/AU4817200A/en not_active Abandoned
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