JP2002542307A5 - - Google Patents
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- JP2002542307A5 JP2002542307A5 JP2000613567A JP2000613567A JP2002542307A5 JP 2002542307 A5 JP2002542307 A5 JP 2002542307A5 JP 2000613567 A JP2000613567 A JP 2000613567A JP 2000613567 A JP2000613567 A JP 2000613567A JP 2002542307 A5 JP2002542307 A5 JP 2002542307A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- compound
- aryl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000000217 alkyl group Chemical group 0.000 description 44
- 125000003118 aryl group Chemical group 0.000 description 44
- 238000000034 method Methods 0.000 description 44
- 150000001875 compounds Chemical class 0.000 description 37
- 125000004429 atom Chemical group 0.000 description 29
- 239000003054 catalyst Substances 0.000 description 28
- 125000002947 alkylene group Chemical group 0.000 description 11
- 125000000732 arylene group Chemical group 0.000 description 11
- 125000006575 electron-withdrawing group Chemical group 0.000 description 11
- 229910052723 transition metal Inorganic materials 0.000 description 11
- 125000002252 acyl group Chemical group 0.000 description 9
- 125000004453 alkoxycarbonyl group Chemical group 0.000 description 9
- 150000007942 carboxylates Chemical class 0.000 description 9
- 150000008049 diazo compounds Chemical class 0.000 description 9
- 125000000623 heterocyclic group Chemical group 0.000 description 8
- 125000003808 silyl group Chemical group [H][Si]([H])([H])[*] 0.000 description 8
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 8
- -1 4-(t-butyl) phenyl Chemical group 0.000 description 7
- 239000003446 ligand Substances 0.000 description 7
- 229910052751 metal Inorganic materials 0.000 description 7
- 239000002184 metal Substances 0.000 description 7
- 229920002554 vinyl polymer Polymers 0.000 description 7
- 125000003545 alkoxy group Chemical group 0.000 description 6
- 150000002391 heterocyclic compounds Chemical class 0.000 description 6
- 0 *[C@](CNC1)*=C1NC(CNC1)=*[C@]1O Chemical compound *[C@](CNC1)*=C1NC(CNC1)=*[C@]1O 0.000 description 5
- 150000003997 cyclic ketones Chemical class 0.000 description 4
- MGNZXYYWBUKAII-UHFFFAOYSA-N cyclohexa-1,3-diene Chemical compound C1CC=CC=C1 MGNZXYYWBUKAII-UHFFFAOYSA-N 0.000 description 4
- 125000001989 1,3-phenylene group Chemical group [H]C1=C([H])C([*:1])=C([H])C([*:2])=C1[H] 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229910052703 rhodium Inorganic materials 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 150000003624 transition metals Chemical group 0.000 description 3
- BTIIGNUPPKUQAP-UHFFFAOYSA-N [1-[2,3-dihydroxy-4-[4-(oxoazaniumylmethylidene)pyridin-1-yl]butyl]pyridin-4-ylidene]methyl-oxoazanium;diperchlorate Chemical compound [O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O.C1=CC(=C[NH+]=O)C=CN1CC(O)C(O)CN1C=CC(=C[NH+]=O)C=C1 BTIIGNUPPKUQAP-UHFFFAOYSA-N 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- HGCIXCUEYOPUTN-UHFFFAOYSA-N cis-cyclohexene Natural products C1CCC=CC1 HGCIXCUEYOPUTN-UHFFFAOYSA-N 0.000 description 2
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 229910052707 ruthenium Inorganic materials 0.000 description 2
- 150000000000 tetracarboxylic acids Chemical class 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 description 1
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 description 1
- VOTZHAZMXFYESM-UHFFFAOYSA-N [Li]C1=CC=CC([Li])=C1 Chemical compound [Li]C1=CC=CC([Li])=C1 VOTZHAZMXFYESM-UHFFFAOYSA-N 0.000 description 1
- 125000006242 amine protecting group Chemical group 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 150000001923 cyclic compounds Chemical class 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 229910052702 rhenium Inorganic materials 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000004665 trialkylsilyl group Chemical group 0.000 description 1
- 125000005106 triarylsilyl group Chemical group 0.000 description 1
- 229910052726 zirconium Inorganic materials 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13126299P | 1999-04-27 | 1999-04-27 | |
| US60/131,262 | 1999-04-27 | ||
| US09/521,375 | 2000-03-08 | ||
| US09/521,375 US6410746B1 (en) | 1999-04-27 | 2000-03-08 | Metal cataltsts and methods for making and using same |
| PCT/US2000/011287 WO2000064583A1 (en) | 1999-04-27 | 2000-04-26 | Metal catalysts and methods for making and using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002542307A JP2002542307A (ja) | 2002-12-10 |
| JP2002542307A5 true JP2002542307A5 (enExample) | 2007-07-05 |
Family
ID=26829299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000613567A Pending JP2002542307A (ja) | 1999-04-27 | 2000-04-26 | 金属触媒及びその製造方法及び利用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6410746B1 (enExample) |
| EP (1) | EP1173278B1 (enExample) |
| JP (1) | JP2002542307A (enExample) |
| AT (1) | ATE270149T1 (enExample) |
| AU (1) | AU4669200A (enExample) |
| CA (1) | CA2370823C (enExample) |
| DE (1) | DE60011887T2 (enExample) |
| MX (1) | MXPA01010900A (enExample) |
| WO (1) | WO2000064583A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030170181A1 (en) * | 1999-04-06 | 2003-09-11 | Midha Kamal K. | Method for preventing abuse of methylphenidate |
| US6410746B1 (en) * | 1999-04-27 | 2002-06-25 | Research Foundation Of State University Of New York, The | Metal cataltsts and methods for making and using same |
| US20020187192A1 (en) * | 2001-04-30 | 2002-12-12 | Yatindra Joshi | Pharmaceutical composition which reduces or eliminates drug abuse potential |
| AU2002332696A1 (en) * | 2001-08-27 | 2003-03-10 | The Research Foundation Of State University Of New York | Solid support dirhodium catalyst compositions and methods for making and using same |
| AU2002331753A1 (en) * | 2001-08-27 | 2003-03-10 | The Research Foundation Of State University Of New York | Dirhodium catalyst compositions and methods for using same |
| ITMI20012267A1 (it) * | 2001-10-29 | 2003-04-29 | Chemi Spa | Preparazione ed uso di un catalizzatore eterogeneo per l'idrogenerazione di un doppio legame di un composto carbonilico b-insaturo |
| US7700798B1 (en) | 2005-06-08 | 2010-04-20 | The Research Foundation Of State University Of New York | Erogorgiaene congeners and methods and intermediates useful in the preparation of same |
| US7816536B2 (en) * | 2005-06-10 | 2010-10-19 | The Research Foundation Of State University Of New York | 4-substituted and 7-substituted indoles, benzofurans, benzothiophenes, benzimidazoles, benzoxazoles, and benzothiazoles and methods for making same |
| US7385064B1 (en) | 2005-11-30 | 2008-06-10 | The Research Foundation Of State University Of New York | Catalysts for use in enantioselective synthesis |
| US8329741B2 (en) * | 2007-06-22 | 2012-12-11 | The Research Foundation Of State University Of New York | Substituted pyrrolidine compounds with central nervous system activity |
| JP5725160B2 (ja) * | 2011-03-31 | 2015-05-27 | トヨタ自動車株式会社 | 車両用大気浄化装置 |
| WO2012145234A2 (en) * | 2011-04-21 | 2012-10-26 | Emory University | Cyclopropyl derivatives and methods of use |
| WO2012167198A2 (en) * | 2011-06-03 | 2012-12-06 | Emory University | Dirhodium catalyst compositions and synthetic processes related thereto |
| SG10201408115SA (en) * | 2014-12-05 | 2016-07-28 | Chakra Biotech Pte Ltd | Use of tetrahydropyridines in the treatment of sodium channel related disease and disorders |
| US20240190804A1 (en) * | 2021-02-10 | 2024-06-13 | Emory University | Diruthenium Catalyst Compositions and Synthetic Processes Related Thereto |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2507631A (en) | 1944-01-19 | 1950-05-16 | Ciba Pharm Prod Inc | Pyridine and piperidine compounds and process of making same |
| US2957880A (en) | 1953-12-23 | 1960-10-25 | Ciba Pharm Prod Inc | Process for the conversion of stereoisomers |
| US4133881A (en) | 1977-04-27 | 1979-01-09 | A. H. Robins Company, Incorporated | Azetidinyl acetonitrile and acetamide antiarrhythmia compositions and methods |
| US4238488A (en) | 1978-11-17 | 1980-12-09 | Imperial Chemical Industries Limited | Carboxylic acid derivatives of N-substituted benzyl-1,2,5,6-tetrahydropyridines |
| WO1987000834A1 (en) | 1985-08-02 | 1987-02-12 | Leo Pharmaceutical Products Ltd. A/S | Novel vitamin d analogues |
| US5036053A (en) | 1988-05-27 | 1991-07-30 | Warner-Lambert Company | Diol-containing renin inhibitors |
| US5401732A (en) | 1989-02-23 | 1995-03-28 | Leo Pharmaceutical Products Ltd. A/S Kemiske Fabrik Produkionsaktiese Skab | Vitamin D analogues |
| US5175311A (en) | 1990-03-29 | 1992-12-29 | Research Corporation Technologies, Inc. | Method of enantioselective cyclopropanation using chiral catalysts |
| GB9201920D0 (en) | 1992-01-29 | 1992-03-18 | Leo Pharm Prod Ltd | Novel treatment i |
| AU4890096A (en) * | 1995-03-10 | 1996-10-02 | Nissan Chemical Industries Ltd. | Titanium catalyst, organotitanium reaction reagent, processes for producing these, and method of reaction using these |
| US5665890A (en) | 1995-03-14 | 1997-09-09 | President And Fellows Of Harvard College | Stereoselective ring opening reactions |
| US6025502A (en) | 1999-03-19 | 2000-02-15 | The Trustees Of The University Of Pennsylvania | Enantopselective synthesis of methyl phenidate |
| US6410746B1 (en) | 1999-04-27 | 2002-06-25 | Research Foundation Of State University Of New York, The | Metal cataltsts and methods for making and using same |
-
2000
- 2000-03-08 US US09/521,375 patent/US6410746B1/en not_active Expired - Lifetime
- 2000-04-26 AT AT00928452T patent/ATE270149T1/de not_active IP Right Cessation
- 2000-04-26 CA CA002370823A patent/CA2370823C/en not_active Expired - Fee Related
- 2000-04-26 MX MXPA01010900A patent/MXPA01010900A/es active IP Right Grant
- 2000-04-26 AU AU46692/00A patent/AU4669200A/en not_active Abandoned
- 2000-04-26 EP EP00928452A patent/EP1173278B1/en not_active Expired - Lifetime
- 2000-04-26 JP JP2000613567A patent/JP2002542307A/ja active Pending
- 2000-04-26 WO PCT/US2000/011287 patent/WO2000064583A1/en not_active Ceased
- 2000-04-26 DE DE60011887T patent/DE60011887T2/de not_active Expired - Fee Related
-
2002
- 2002-03-30 US US10/113,747 patent/US6762304B2/en not_active Expired - Lifetime
-
2004
- 2004-04-05 US US10/817,443 patent/US7109343B2/en not_active Expired - Fee Related
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