JP2002541101A - スチリルスルホン抗癌剤 - Google Patents
スチリルスルホン抗癌剤Info
- Publication number
- JP2002541101A JP2002541101A JP2000609058A JP2000609058A JP2002541101A JP 2002541101 A JP2002541101 A JP 2002541101A JP 2000609058 A JP2000609058 A JP 2000609058A JP 2000609058 A JP2000609058 A JP 2000609058A JP 2002541101 A JP2002541101 A JP 2002541101A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- cells
- hydrogen
- fluorine
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/02—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms
- C07C317/10—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1999/007406 WO2000059494A1 (en) | 1999-04-02 | 1999-04-02 | Styryl sulfone anticancer agents |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2002541101A true JP2002541101A (ja) | 2002-12-03 |
JP2002541101A5 JP2002541101A5 (es) | 2006-06-08 |
Family
ID=22272500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000609058A Pending JP2002541101A (ja) | 1999-04-02 | 1999-04-02 | スチリルスルホン抗癌剤 |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP2002541101A (es) |
AU (1) | AU3381399A (es) |
WO (1) | WO2000059494A1 (es) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005531503A (ja) * | 2002-02-28 | 2005-10-20 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 増殖性疾患を治療するためのアミノ置換(e)−2,6−ジアルコキシスチリル−4−置換ベンジルスルホン |
JP2007513877A (ja) * | 2003-11-14 | 2007-05-31 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 増殖性疾患を治療するためのα,β−不飽和スルホキシド |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1173160B1 (en) * | 1999-04-02 | 2005-06-22 | Temple University of the Commonwealth System of Higher Education | (e)-styryl sulfone anticancer agents |
US6541475B2 (en) * | 2000-04-14 | 2003-04-01 | Temple University - Of The Commonwealth System Of Higher Education | α, β-unsaturated sulfones for treating proliferative disorders |
US6486210B2 (en) * | 2000-04-14 | 2002-11-26 | Temple University—Of the Commonwealth System of Higher Education | Substituted styryl benzylsulfones for treating proliferative disorders |
JP4302986B2 (ja) * | 2001-02-28 | 2009-07-29 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 細胞及び組織をα,β不飽和アリールスルホンにより電離放射線から防護する方法 |
EP2091527B1 (en) * | 2006-12-13 | 2016-03-23 | Temple University - Of The Commonwealth System of Higher Education | Sulfide, sulfoxide and sulfone chalcone analogues, derivatives thereof and therapeutic uses thereof |
US8686190B2 (en) | 2008-04-10 | 2014-04-01 | The Uab Research Foundation | Bis-aromatic anticancer agents |
-
1999
- 1999-04-02 JP JP2000609058A patent/JP2002541101A/ja active Pending
- 1999-04-02 WO PCT/US1999/007406 patent/WO2000059494A1/en active Application Filing
- 1999-04-02 AU AU33813/99A patent/AU3381399A/en not_active Abandoned
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005531503A (ja) * | 2002-02-28 | 2005-10-20 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 増殖性疾患を治療するためのアミノ置換(e)−2,6−ジアルコキシスチリル−4−置換ベンジルスルホン |
JP2007513877A (ja) * | 2003-11-14 | 2007-05-31 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 増殖性疾患を治療するためのα,β−不飽和スルホキシド |
Also Published As
Publication number | Publication date |
---|---|
WO2000059494A1 (en) | 2000-10-12 |
AU3381399A (en) | 2000-10-23 |
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US6548553B2 (en) | Styryl sulfone anticancer agents | |
JP4468593B2 (ja) | Z−スチリルスルホン抗癌剤 | |
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JP4677162B2 (ja) | 増殖性障害を治療するための置換スチリルベンジルスルホン | |
AU2001251615A1 (en) | Substituted styryl benzylsulfones for treating proliferative disorders | |
EP1292308B1 (en) | Alpha,beta-unsaturated sulfones for treating proliferative disorders | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060329 |
|
A524 | Written submission of copy of amendment under section 19 (pct) |
Free format text: JAPANESE INTERMEDIATE CODE: A524 Effective date: 20060329 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20060329 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090616 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20091124 |