JP2002529075A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002529075A5 JP2002529075A5 JP2000581169A JP2000581169A JP2002529075A5 JP 2002529075 A5 JP2002529075 A5 JP 2002529075A5 JP 2000581169 A JP2000581169 A JP 2000581169A JP 2000581169 A JP2000581169 A JP 2000581169A JP 2002529075 A5 JP2002529075 A5 JP 2002529075A5
- Authority
- JP
- Japan
- Prior art keywords
- substance
- expression vector
- cell
- protein
- rhesus monkey
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000004027 cell Anatomy 0.000 description 69
- 239000000126 substance Substances 0.000 description 43
- 239000013604 expression vector Substances 0.000 description 35
- 238000000034 method Methods 0.000 description 24
- 241000282560 Macaca mulatta Species 0.000 description 23
- 102000004169 proteins and genes Human genes 0.000 description 21
- 108090000623 proteins and genes Proteins 0.000 description 21
- 239000012528 membrane Substances 0.000 description 14
- 230000014509 gene expression Effects 0.000 description 11
- 239000005557 antagonist Substances 0.000 description 9
- 239000003446 ligand Substances 0.000 description 9
- INAPMGSXUVUWAF-GCVPSNMTSA-N [(2r,3s,5r,6r)-2,3,4,5,6-pentahydroxycyclohexyl] dihydrogen phosphate Chemical compound OC1[C@H](O)[C@@H](O)C(OP(O)(O)=O)[C@H](O)[C@@H]1O INAPMGSXUVUWAF-GCVPSNMTSA-N 0.000 description 8
- 125000003275 alpha amino acid group Chemical group 0.000 description 8
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 6
- 108020004414 DNA Proteins 0.000 description 6
- 102000053602 DNA Human genes 0.000 description 6
- 239000000556 agonist Substances 0.000 description 6
- 230000001131 transforming effect Effects 0.000 description 6
- 102000030612 Melanocortin 5 receptor Human genes 0.000 description 5
- 108010088565 Melanocortin 5 receptor Proteins 0.000 description 5
- 210000000170 cell membrane Anatomy 0.000 description 5
- 239000002773 nucleotide Substances 0.000 description 5
- 125000003729 nucleotide group Chemical group 0.000 description 5
- 102000005962 receptors Human genes 0.000 description 4
- 108020003175 receptors Proteins 0.000 description 4
- 108091006027 G proteins Proteins 0.000 description 3
- 102000030782 GTP binding Human genes 0.000 description 3
- 108091000058 GTP-Binding Proteins 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 230000003834 intracellular effect Effects 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 230000009465 prokaryotic expression Effects 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10763298P | 1998-11-09 | 1998-11-09 | |
| US60/107,632 | 1998-11-09 | ||
| PCT/US1999/025755 WO2000028002A1 (en) | 1998-11-09 | 1999-11-05 | Dna molecules encoding the melanocortin 5 receptor protein from rhesus monkey |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002529075A JP2002529075A (ja) | 2002-09-10 |
| JP2002529075A5 true JP2002529075A5 (https=) | 2006-12-28 |
Family
ID=22317601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000581169A Withdrawn JP2002529075A (ja) | 1998-11-09 | 1999-11-05 | アカゲザルのメラノコルチン５受容体タンパク質をコードするｄｎａ分子 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6645738B1 (https=) |
| EP (1) | EP1137757A1 (https=) |
| JP (1) | JP2002529075A (https=) |
| CA (1) | CA2349848A1 (https=) |
| WO (1) | WO2000028002A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005054849A2 (en) * | 2003-12-06 | 2005-06-16 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled receptor mc5 (mc5r) |
| US8343958B2 (en) | 2008-02-29 | 2013-01-01 | Mimetica Pty Ltd | 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5-receptor antagonists |
| US8008291B2 (en) * | 2008-02-29 | 2011-08-30 | Mimetica Pty Ltd | 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5 receptor antagonists |
| US8377925B2 (en) * | 2008-02-29 | 2013-02-19 | Mimetica Pty Ltd | Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5280112A (en) | 1992-04-10 | 1994-01-18 | State Of Oregon, Oregon Health Sciences University | DNA sequence encoding bovine and human adrenocorticotropic hormone receptors |
| US5532347A (en) | 1992-04-10 | 1996-07-02 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization | DNA encoding α melanocyte stimulating hormone receptor |
| US5622860A (en) | 1994-02-17 | 1997-04-22 | The Regents Of The University Of Michigan | Genes encoding melanocortin receptors |
-
1999
- 1999-11-05 CA CA002349848A patent/CA2349848A1/en not_active Abandoned
- 1999-11-05 JP JP2000581169A patent/JP2002529075A/ja not_active Withdrawn
- 1999-11-05 EP EP99956857A patent/EP1137757A1/en not_active Withdrawn
- 1999-11-05 WO PCT/US1999/025755 patent/WO2000028002A1/en not_active Ceased
- 1999-11-05 US US09/831,228 patent/US6645738B1/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11226339B2 (en) | Methods for high throughput receptor:ligand identification | |
| JP2004513608A5 (https=) | ||
| Chang et al. | Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif | |
| JP2003510037A5 (https=) | ||
| CA2335318A1 (en) | Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction | |
| CA2299624A1 (en) | Mammalian cytokine receptor - 11 | |
| WO2002028901A3 (en) | Seven-transmembrane (7tm) receptors and uses thereof | |
| WO2001064882A3 (en) | 1983, 52881, 2398, 45449, 50289, and 52872, g protein-coupled receptors and uses therefor | |
| CA2309903A1 (en) | Nucleic acid sequences encoding capsaicin receptor | |
| CA2192694A1 (en) | Cloning and expression of an acetylcholine-gated ion channel receptor subunit | |
| PT973794E (pt) | Receptores de netrina | |
| CA2343979A1 (en) | Human interleukin-b50, therapeutic uses | |
| CA3143567A1 (en) | Peptide-mhc complexes | |
| JP2005537027A5 (https=) | ||
| Kolb et al. | Molecular analysis of the coronavirus-receptor function of aminopeptidase N | |
| Maeda et al. | Original ligand for LTβR is LIGHT: insight into evolution of the LT/LTβR system | |
| WO2008001944A1 (en) | Reagent for detection of autoantibody and kit for diagnosis of autoimmune disease | |
| WO1997026853A3 (en) | Dna encoding galanin galr2 receptors and uses thereof | |
| JP2002536989A5 (https=) | ||
| Ludwig et al. | High‐throughput single‐cell sequencing of paired TCRα and TCRβ genes for the direct expression‐cloning and functional analysis of murine T‐cell receptors | |
| JP2002529075A5 (https=) | ||
| CN109666699B (zh) | 一种基于lag-3/mhc ii阻断功能及其生物效应的药物快速筛选方法 | |
| Wei et al. | DR* W201/P65 tetramer visualization of epitope-specific CD4 T-cell during M. tuberculosis infection and its resting memory pool after BCG vaccination | |
| JP2017525368A5 (https=) | ||
| WO2002038767A3 (en) | G protein-coupled receptor protein and nucleic acid molecules and uses therefor |