JP2002524528A5 - - Google Patents
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- Publication number
- JP2002524528A5 JP2002524528A5 JP2000569830A JP2000569830A JP2002524528A5 JP 2002524528 A5 JP2002524528 A5 JP 2002524528A5 JP 2000569830 A JP2000569830 A JP 2000569830A JP 2000569830 A JP2000569830 A JP 2000569830A JP 2002524528 A5 JP2002524528 A5 JP 2002524528A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9995298P | 1998-09-11 | 1998-09-11 | |
| US60/099,952 | 1998-09-11 | ||
| PCT/US1999/020500 WO2000015246A2 (en) | 1998-09-11 | 1999-09-10 | Regulation of lung tissue by hedgehog-like polypeptides, and formulations and uses related thereto |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002524528A JP2002524528A (ja) | 2002-08-06 |
| JP2002524528A5 true JP2002524528A5 (https=) | 2005-12-15 |
Family
ID=22277390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000569830A Pending JP2002524528A (ja) | 1998-09-11 | 1999-09-10 | ヘッジホッグ様ポリペプチドによる肺組織の調節、およびそれに関する製剤および使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7691593B2 (https=) |
| EP (1) | EP1109569A2 (https=) |
| JP (1) | JP2002524528A (https=) |
| AU (1) | AU761298C (https=) |
| CA (1) | CA2341683C (https=) |
| WO (1) | WO2000015246A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69841320D1 (de) * | 1997-02-10 | 2010-01-07 | Harvard College | Verfahren zur modulation von hämatopoese und vaskulärem wachstum |
| US6639051B2 (en) * | 1997-10-20 | 2003-10-28 | Curis, Inc. | Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto |
| JP2002524528A (ja) * | 1998-09-11 | 2002-08-06 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | ヘッジホッグ様ポリペプチドによる肺組織の調節、およびそれに関する製剤および使用方法 |
| ATE283700T1 (de) * | 1999-06-08 | 2004-12-15 | Lorantis Ltd | Therapeutische verwendung eines inhibitors des hedgehog signalübertragungsweges |
| US7498304B2 (en) | 2000-06-16 | 2009-03-03 | Curis, Inc. | Angiogenesis-modulating compositions and uses |
| US20040060568A1 (en) * | 2000-10-13 | 2004-04-01 | Henryk Dudek | Hedgehog antagonists, methods and uses related thereto |
| US7708998B2 (en) | 2000-10-13 | 2010-05-04 | Curis, Inc. | Methods of inhibiting unwanted cell proliferation using hedgehog antagonists |
| WO2005097207A2 (en) | 2004-03-26 | 2005-10-20 | Curis, Inc. | Rna interference modulators of hedgehog signaling and uses thereof |
| US8410246B2 (en) | 2004-06-17 | 2013-04-02 | Thrasos, Inc. | TDF-related compounds and analogs thereof |
| DK2497780T3 (en) | 2005-09-20 | 2015-06-01 | Thrasos Innovation Inc | TDF-related compounds and analogs thereof |
| WO2010027802A2 (en) | 2008-08-25 | 2010-03-11 | New York University | Methods for treating diabetic wounds |
| WO2010129537A1 (en) * | 2009-05-05 | 2010-11-11 | The Johns Hopkins University | Phosphopeptides as melanoma vaccines |
| WO2011160082A2 (en) | 2010-06-17 | 2011-12-22 | New York University | Therapeutic and cosmetic uses and applications of calreticulin |
| WO2015073691A1 (en) | 2013-11-14 | 2015-05-21 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treating cancer by activation of bmp signaling |
| WO2019048898A1 (en) | 2017-09-05 | 2019-03-14 | INSERM (Institut National de la Santé et de la Recherche Médicale) | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5789543A (en) * | 1993-12-30 | 1998-08-04 | President And Fellows Of Harvard College | Vertebrate embryonic pattern-inducing proteins and uses related thereto |
| US6610656B1 (en) * | 1993-12-30 | 2003-08-26 | President And Fellows Of Harvard College | Method of promoting chondrocyte differentiation with hedgehog related polypeptides |
| US6884775B1 (en) * | 1993-12-30 | 2005-04-26 | President And Fellows Of Harvard College | Methods and compositions for regulating skeletogenic formation |
| US20030186357A1 (en) * | 1993-12-30 | 2003-10-02 | Philip W. Ingham | Vertebrate embryonic pattern-inducing proteins, and uses related thereto |
| US7060450B1 (en) * | 1993-12-30 | 2006-06-13 | President And Fellows Of Harvard College | Screening assays for agonists and antagonists of the hedgehog signaling pathway |
| US6165747A (en) * | 1993-12-30 | 2000-12-26 | President & Fellows Of Harvard College | Nucleic acids encoding hedgehog proteins |
| EP0741783B1 (en) | 1993-12-30 | 2009-03-18 | President And Fellows Of Harvard College | Vertebrate embryonic pattern-inducing hedgehog-like proteins |
| US6261786B1 (en) * | 1993-12-30 | 2001-07-17 | Imperial Cancer Res. Technology | Screening assays for hedgehog agonists and antagonists |
| US6271363B1 (en) * | 1993-12-30 | 2001-08-07 | President & Fellows Of Harvard College | Nucleic acids encoding hedgehog proteins |
| JPH09509574A (ja) | 1994-02-25 | 1997-09-30 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク | 脊索によって発現されるヘッジホッグ、Ｖｈｈ−１、の脊椎動物相同体をコードするＤＮＡ、及びこれらの使用 |
| US5681278A (en) * | 1994-06-23 | 1997-10-28 | Cormedics Corp. | Coronary vasculature treatment method |
| CA2201887C (en) * | 1994-10-07 | 2009-04-14 | Matthew P. Scott | Patched genes and their use |
| US6946257B1 (en) * | 1994-10-07 | 2005-09-20 | Regents Of The University Of California | Patched genes and uses related thereto |
| US6429354B1 (en) * | 1994-10-07 | 2002-08-06 | The Board Of Trustees Of The Leland Stanford Junior University | Patched genes and uses related thereto |
| US6027882A (en) * | 1994-10-07 | 2000-02-22 | The Regents Of The University Of California | Patched genes and their use for diagnostics |
| US6281332B1 (en) | 1994-12-02 | 2001-08-28 | The Johns Hopkins University School Of Medicine | Hedgehog-derived polypeptides |
| DE69841320D1 (de) | 1997-02-10 | 2010-01-07 | Harvard College | Verfahren zur modulation von hämatopoese und vaskulärem wachstum |
| US6639051B2 (en) | 1997-10-20 | 2003-10-28 | Curis, Inc. | Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto |
| US6432970B2 (en) * | 1998-04-09 | 2002-08-13 | Johns Hopkins University School Of Medicine | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto |
| US6867216B1 (en) * | 1998-04-09 | 2005-03-15 | Johns Hopkins University School Of Medicine | Inhibitors of hedgehog signal pathways, compositions and uses related thereto |
| JP5067986B2 (ja) | 1998-04-09 | 2012-11-07 | ジョンズ ホプキンズ ユニヴァーシティー スクール オブ メディシン | ヘッジホッグシグナリング経路の阻害剤としてのステロイドアルカロイド誘導体の使用 |
| AU773044B2 (en) * | 1998-09-11 | 2004-05-13 | Curis, Inc. | Hedgehog and patched antagonists for inhibiting cell and tissue growth and differentiation and uses therefor |
| JP2002524528A (ja) * | 1998-09-11 | 2002-08-06 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | ヘッジホッグ様ポリペプチドによる肺組織の調節、およびそれに関する製剤および使用方法 |
| JP4994552B2 (ja) * | 1999-09-16 | 2012-08-08 | キュリス，インコーポレイテッド | ヘッジホッグシグナル伝達経路のメディエーター、組成物及びそれらと関連する利用 |
| US6552016B1 (en) * | 1999-10-14 | 2003-04-22 | Curis, Inc. | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| US6613798B1 (en) * | 2000-03-30 | 2003-09-02 | Curis, Inc. | Small organic molecule regulators of cell proliferation |
| US7498304B2 (en) * | 2000-06-16 | 2009-03-03 | Curis, Inc. | Angiogenesis-modulating compositions and uses |
| AU7549501A (en) | 2000-06-16 | 2002-01-02 | Biogen Inc | Angiogenesis-modulating compositions and uses |
| US20040060568A1 (en) * | 2000-10-13 | 2004-04-01 | Henryk Dudek | Hedgehog antagonists, methods and uses related thereto |
| US7708998B2 (en) * | 2000-10-13 | 2010-05-04 | Curis, Inc. | Methods of inhibiting unwanted cell proliferation using hedgehog antagonists |
-
1999
- 1999-09-10 JP JP2000569830A patent/JP2002524528A/ja active Pending
- 1999-09-10 WO PCT/US1999/020500 patent/WO2000015246A2/en not_active Ceased
- 1999-09-10 CA CA2341683A patent/CA2341683C/en not_active Expired - Lifetime
- 1999-09-10 AU AU62441/99A patent/AU761298C/en not_active Expired
- 1999-09-10 EP EP99949603A patent/EP1109569A2/en not_active Withdrawn
-
2003
- 2003-12-03 US US10/727,195 patent/US7691593B2/en not_active Expired - Fee Related
-
2010
- 2010-03-22 US US12/728,948 patent/US20110124580A1/en not_active Abandoned
-
2012
- 2012-08-30 US US13/599,879 patent/US20130085096A1/en not_active Abandoned