JP2002520008A5 - - Google Patents

Download PDF

Info

Publication number
JP2002520008A5
JP2002520008A5 JP2000559128A JP2000559128A JP2002520008A5 JP 2002520008 A5 JP2002520008 A5 JP 2002520008A5 JP 2000559128 A JP2000559128 A JP 2000559128A JP 2000559128 A JP2000559128 A JP 2000559128A JP 2002520008 A5 JP2002520008 A5 JP 2002520008A5
Authority
JP
Japan
Prior art keywords
pna
library
oligomer
nucleotide
base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000559128A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002520008A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1999/014969 external-priority patent/WO2000002899A1/en
Publication of JP2002520008A publication Critical patent/JP2002520008A/ja
Publication of JP2002520008A5 publication Critical patent/JP2002520008A5/ja
Pending legal-status Critical Current

Links

JP2000559128A 1998-07-09 1999-07-01 Dna配列ハイブリッド形成を最適化するための改良されたペプチド核酸汎用ライブラリーの使用法 Pending JP2002520008A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11321198A 1998-07-09 1998-07-09
US09/113,211 1998-07-09
PCT/US1999/014969 WO2000002899A1 (en) 1998-07-09 1999-07-01 Method of using an improved peptide nucleic acid universal library to optimize dna sequence hybridation

Publications (2)

Publication Number Publication Date
JP2002520008A JP2002520008A (ja) 2002-07-09
JP2002520008A5 true JP2002520008A5 (https=) 2006-08-17

Family

ID=22348188

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000559128A Pending JP2002520008A (ja) 1998-07-09 1999-07-01 Dna配列ハイブリッド形成を最適化するための改良されたペプチド核酸汎用ライブラリーの使用法

Country Status (8)

Country Link
US (1) US6433134B1 (https=)
EP (1) EP1095054B1 (https=)
JP (1) JP2002520008A (https=)
KR (1) KR100694914B1 (https=)
AT (1) ATE343586T1 (https=)
AU (1) AU4965499A (https=)
DE (1) DE69933770D1 (https=)
WO (1) WO2000002899A1 (https=)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7256275B2 (en) * 2001-03-09 2007-08-14 Boston Probes, Inc. Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation
EP1373472B1 (en) * 2001-04-03 2007-06-27 Biocept, Inc. Methods and gel compositions for encapsulating living cells and organic molecules
EP1421216A4 (en) * 2001-09-01 2006-05-17 Samsung Electronics Co Ltd PROCESS FOR PRODUCING A HYDROGEL BIOPUCE USING AN ETOILE POLYETHYLENE GLYCOL DERIVATIVE COMPRISING AN EPOXY GROUP
WO2003040395A2 (en) 2001-11-07 2003-05-15 Applera Corporation Universal nucleotides for nucleic acid analysis
WO2003046144A2 (en) * 2001-11-26 2003-06-05 Molecular Reflections, Inc. Microscale immobilization of molecules using a hydrogel and methods of use thereof
KR100464261B1 (ko) 2002-01-24 2005-01-03 주식회사 파나진 Pna 올리고머를 합성하기 위한 신규한 단량체 및 그의제조방법
US20030175828A1 (en) * 2002-03-15 2003-09-18 Lazar James G. Signal amplification by Hybrid Capture
KR20030084444A (ko) 2002-04-26 2003-11-01 주식회사 파나진 Pna 올리고머를 합성하기 위한 신규한 단량체 및 그의제조방법
DE60330182D1 (de) * 2002-09-08 2009-12-31 Applera Corp Festphasengebundene PNA-Dimere und deren Synthese
WO2004111072A2 (en) * 2003-06-12 2004-12-23 Applera Corporation Combinatorial nucleobase oligomers comprising universal base analogues and methods for making and using same
US7211668B2 (en) * 2003-07-28 2007-05-01 Panagene, Inc. PNA monomer and precursor
WO2006076650A2 (en) * 2005-01-12 2006-07-20 Applera Corporation Compositions, methods, and kits for selective amplification of nucleic acids
US7482353B2 (en) 2005-06-15 2009-01-27 Applied Biosystems Inc. Compositions and methods pertaining to PNA synthons and oligomers comprising a universal base
US20070212704A1 (en) 2005-10-03 2007-09-13 Applera Corporation Compositions, methods, and kits for amplifying nucleic acids
US20070172842A1 (en) * 2006-01-25 2007-07-26 Andreas Braun Methods for isolating and identifying novel target-specific structuremers for use in the biological sciences
US10466160B2 (en) 2011-08-01 2019-11-05 Celsee Diagnostics, Inc. System and method for retrieving and analyzing particles
US9174216B2 (en) 2013-03-13 2015-11-03 DeNovo Science, Inc. System for capturing and analyzing cells
US9404864B2 (en) 2013-03-13 2016-08-02 Denovo Sciences, Inc. System for imaging captured cells
CN103998394B (zh) 2011-08-01 2016-08-17 德诺弗科学公司 细胞捕获系统和使用方法
US9752181B2 (en) 2013-01-26 2017-09-05 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US9707562B2 (en) 2013-03-13 2017-07-18 Denovo Sciences, Inc. System for capturing and analyzing cells
US10391490B2 (en) 2013-05-31 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
US9856535B2 (en) 2013-05-31 2018-01-02 Denovo Sciences, Inc. System for isolating cells
JP6640079B2 (ja) 2013-10-16 2020-02-05 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 小容積の粒子を調製するためのデバイス及び方法
WO2016138175A1 (en) 2015-02-24 2016-09-01 The University Of British Columbia Continuous flow microfluidic system
EP3400097B1 (en) 2016-01-06 2021-01-27 The University Of British Columbia Bifurcating mixers and methods of their use and manufacture
CN106117153B (zh) * 2016-07-05 2018-11-23 淮阴师范学院 2-哌嗪酮的制备方法
WO2018191389A1 (en) * 2017-04-12 2018-10-18 Roche Sequencing Solutions, Inc. A method for sequencing reaction with tagged nucleoside obtained via pictet spengler reaction
US10391492B2 (en) 2017-08-29 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
WO2019089567A1 (en) 2017-10-30 2019-05-09 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
US10633693B1 (en) 2019-04-16 2020-04-28 Celsee Diagnostics, Inc. System and method for leakage control in a particle capture system
AU2020267743B2 (en) 2019-05-07 2023-04-06 Bio-Rad Laboratories, Inc. System and method for automated single cell processing
US11273439B2 (en) 2019-05-07 2022-03-15 Bio-Rad Laboratories, Inc. System and method for target material retrieval from microwells
WO2021002984A1 (en) 2019-05-30 2021-01-07 Massachusetts Institute Of Technology Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
WO2020251802A1 (en) 2019-06-14 2020-12-17 Bio-Rad Laboratories, Inc. System and method for automated single cell processing and analyses
CN110511973B (zh) * 2019-07-16 2021-05-07 杭州原合生物科技有限公司 一种用于核酸原位合成的固相载体及其制备方法
KR102403904B1 (ko) * 2019-12-24 2022-06-02 주식회사 시선바이오머티리얼스 용액공정상 pna 올리고머의 제조방법
US11504719B2 (en) 2020-03-12 2022-11-22 Bio-Rad Laboratories, Inc. System and method for receiving and delivering a fluid for sample processing
KR20220057138A (ko) 2020-10-29 2022-05-09 엘지전자 주식회사 청소기
CN118369438A (zh) 2021-12-10 2024-07-19 伯乐实验室有限公司 用形态可调节功能化颗粒进行样品处理的组合物、方法和系统
KR102804687B1 (ko) 2023-02-10 2025-05-12 엘지전자 주식회사 청소기 및 청소기 제어 방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005519A1 (en) 1985-03-15 1986-09-25 James Summerton Polynucleotide assay reagent and method
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
US5641625A (en) 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
US5714331A (en) 1991-05-24 1998-02-03 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US5539082A (en) 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
US5766855A (en) 1991-05-24 1998-06-16 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity and sequence specificity
US5700922A (en) * 1991-12-24 1997-12-23 Isis Pharmaceuticals, Inc. PNA-DNA-PNA chimeric macromolecules
US5438131A (en) 1992-09-16 1995-08-01 Bergstrom; Donald E. 3-nitropyrrole nucleoside
US5539083A (en) * 1994-02-23 1996-07-23 Isis Pharmaceuticals, Inc. Peptide nucleic acid combinatorial libraries and improved methods of synthesis
US5738996A (en) 1994-06-15 1998-04-14 Pence, Inc. Combinational library composition and method
AU3999495A (en) 1994-10-06 1996-05-02 Buchardt, Dorte Peptide nucleic acid conjugates
EP0792283A1 (en) 1994-11-14 1997-09-03 Chiron Corporation SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH
WO1996020212A2 (en) * 1994-12-28 1996-07-04 Buchardt, Dorte Peptide nucleic acid incorporating a chiral backbone
DE19532553A1 (de) 1995-09-04 1997-03-06 Hoechst Ag Verfahren zur Herstellung substituierter N-Ethyl-Glycinderivate
DE19627898A1 (de) 1996-07-11 1998-01-15 Hoechst Ag Festphasensynthese von Oligonucleotiden

Similar Documents

Publication Publication Date Title
JP2002520008A5 (https=)
AU2008201349B2 (en) Families of non-cross-hybridizing polynucleotides for use as tags and tag complements, manufacture and use thereof
US5403708A (en) Methods and compositions for determining the sequence of nucleic acids
Studier A strategy for high-volume sequencing of cosmid DNAs: random and directed priming with a library of oligonucleotides.
EP0668932B1 (en) Positional sequencing by hybridization
US6156501A (en) Arrays of modified nucleic acid probes and methods of use
US7794943B2 (en) Modified nucleic acid probes
US7615629B2 (en) Methods and compositions for the tandem synthesis of two or more oligonucleotides on the same solid support
CN101484589B (zh) 使用aflp的高通量物理作图
WO2001048184A3 (de) Verfahren zur parallelen sequenzierung eines nukleinsäuregemisches an einer oberfläche
JPH07505529A (ja) プローブ構成物および方法
AU2002227829A1 (en) Families of non-cross-hybridizing polynucleotides for use as tags and tag complements, manufacture and use thereof
WO2003033718A1 (en) Synthesis of oligonucleotides on solid support and assembly into doublestranded polynucleotides
JP2001521398A (ja) 性状検査用dna
US20080221315A1 (en) Nucleic acid-based translation system and method for decoding nucleic acid encrypted message
Pon et al. Tandem oligonucleotide synthesis using linker phosphoramidites
ATE317123T1 (de) Reaktiver träger zur bestimmung von dna fragmenten
US20040146876A1 (en) Complex element micro-array and methods of use
EP2883963A1 (en) Method for generating of oligonucleotide arrays using in situ block synthesis approach
Potapov et al. Modified oligonucleotides as a tool for DNA sequencing, fingerprinting and mapping
GB2380999A (en) Synthesis of oligonucleotide mixtures, and polynucleotide assembly
Trinca Exact and Approximation Algorithms for DNA Tag Set Design
HK1014561B (en) Modified nucleic acid probes