JP2002518313A - カチオン性両親媒性ミセル複合体 - Google Patents

カチオン性両親媒性ミセル複合体

Info

Publication number
JP2002518313A
JP2002518313A JP2000554341A JP2000554341A JP2002518313A JP 2002518313 A JP2002518313 A JP 2002518313A JP 2000554341 A JP2000554341 A JP 2000554341A JP 2000554341 A JP2000554341 A JP 2000554341A JP 2002518313 A JP2002518313 A JP 2002518313A
Authority
JP
Japan
Prior art keywords
lipid
complex
micelle
micelle complex
cationic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000554341A
Other languages
English (en)
Japanese (ja)
Inventor
タウシグナント、ジェニファー、ディ
チェン、セン、エイチ
イーストマン、サイモン、ジェイ
ニュータプスキイ、ジニファー、ビー
リー、エドワード、アール
チュー、クイミン
シュール、ロナルド、ケイ
マーシャル、ジョン
Original Assignee
ジエンザイム コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジエンザイム コーポレイション filed Critical ジエンザイム コーポレイション
Publication of JP2002518313A publication Critical patent/JP2002518313A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6907—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
JP2000554341A 1998-06-19 1999-06-18 カチオン性両親媒性ミセル複合体 Pending JP2002518313A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8987998P 1998-06-19 1998-06-19
US60/089,879 1998-06-19
PCT/US1999/013875 WO1999065461A2 (fr) 1998-06-19 1999-06-18 Complexes micellaires d'amphiphiles cationiques

Publications (1)

Publication Number Publication Date
JP2002518313A true JP2002518313A (ja) 2002-06-25

Family

ID=22220044

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000554341A Pending JP2002518313A (ja) 1998-06-19 1999-06-18 カチオン性両親媒性ミセル複合体

Country Status (5)

Country Link
EP (1) EP1085857A2 (fr)
JP (1) JP2002518313A (fr)
AU (1) AU4698499A (fr)
CA (1) CA2335638A1 (fr)
WO (1) WO1999065461A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009153888A1 (fr) * 2008-06-19 2009-12-23 日本新薬株式会社 Vecteur de médicament

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852334B1 (en) 1999-04-20 2005-02-08 The University Of British Columbia Cationic peg-lipids and methods of use
WO2000062813A2 (fr) * 1999-04-20 2000-10-26 The University Of British Columbia Lipides peg cationiques et méthodes d'utilisation
US7189705B2 (en) 2000-04-20 2007-03-13 The University Of British Columbia Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers
AU5454801A (en) * 2000-04-20 2001-11-07 Univ British Columbia Methods of enhancing splp-mediated transfection using endosomal membrane destabilizers
JP4590519B2 (ja) * 2006-09-22 2010-12-01 独立行政法人産業技術総合研究所 腸管吸収制御性リポソーム

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286634A (en) * 1989-09-28 1994-02-15 Stadler Joan K Synergistic method for host cell transformation
US5843473A (en) * 1989-10-20 1998-12-01 Sequus Pharmaceuticals, Inc. Method of treatment of infected tissues
WO1996014864A1 (fr) * 1994-11-09 1996-05-23 The Regents Of The University Of California Immunoliposomes optimalisant l'incorporation d'un agent dans des cellules cibles
IL122290A0 (en) * 1995-06-07 1998-04-05 Inex Pharmaceuticals Corp Lipid-nucleic acid complex its preparation and use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009153888A1 (fr) * 2008-06-19 2009-12-23 日本新薬株式会社 Vecteur de médicament

Also Published As

Publication number Publication date
EP1085857A2 (fr) 2001-03-28
AU4698499A (en) 2000-01-05
CA2335638A1 (fr) 1999-12-23
WO1999065461A2 (fr) 1999-12-23
WO1999065461A3 (fr) 2000-02-24
WO1999065461A9 (fr) 2001-02-01

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