JP2002517999A5 - - Google Patents
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- Publication number
- JP2002517999A5 JP2002517999A5 JP2000554765A JP2000554765A JP2002517999A5 JP 2002517999 A5 JP2002517999 A5 JP 2002517999A5 JP 2000554765 A JP2000554765 A JP 2000554765A JP 2000554765 A JP2000554765 A JP 2000554765A JP 2002517999 A5 JP2002517999 A5 JP 2002517999A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8968998P | 1998-06-17 | 1998-06-17 | |
| US60/089,689 | 1998-06-17 | ||
| US12617599P | 1999-03-25 | 1999-03-25 | |
| US60/126,175 | 1999-03-25 | ||
| PCT/US1999/013737 WO1999065940A1 (en) | 1998-06-17 | 1999-06-17 | Anti-angiogenic proteins and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007244618A Division JP2008019271A (ja) | 1998-06-17 | 2007-09-21 | 抗血管形成タンパク質およびその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002517999A JP2002517999A (ja) | 2002-06-25 |
| JP2002517999A5 true JP2002517999A5 (xx) | 2005-12-22 |
Family
ID=26780845
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000554765A Ceased JP2002517999A (ja) | 1998-06-17 | 1999-06-17 | 抗血管形成タンパク質およびその使用方法 |
| JP2007244618A Pending JP2008019271A (ja) | 1998-06-17 | 2007-09-21 | 抗血管形成タンパク質およびその使用方法 |
| JP2008164926A Pending JP2008301823A (ja) | 1998-06-17 | 2008-06-24 | 抗血管形成タンパク質およびその使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007244618A Pending JP2008019271A (ja) | 1998-06-17 | 2007-09-21 | 抗血管形成タンパク質およびその使用方法 |
| JP2008164926A Pending JP2008301823A (ja) | 1998-06-17 | 2008-06-24 | 抗血管形成タンパク質およびその使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1086129A1 (xx) |
| JP (3) | JP2002517999A (xx) |
| KR (1) | KR100682666B1 (xx) |
| CN (1) | CN1309663A (xx) |
| AU (1) | AU753249B2 (xx) |
| CA (1) | CA2331332A1 (xx) |
| IL (1) | IL140239A0 (xx) |
| WO (1) | WO1999065940A1 (xx) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6440729B1 (en) | 1995-06-30 | 2002-08-27 | University Of Kansas Medical Center | Treating angiogenesis-mediated diseases with the α2 monomer of type IV collagen |
| US6358735B1 (en) | 1995-06-30 | 2002-03-19 | University Of Kansas Medical Center | Method for inhibiting angiogenesis and tumors with the isolated NC1 α3 chain monomer of type IV collagen |
| US7387779B2 (en) | 1998-06-17 | 2008-06-17 | Beth Israel Deaconess Medical Center | Anti-angiogenic proteins and fragments and methods of use thereof |
| US6759047B1 (en) | 1998-06-17 | 2004-07-06 | Beth Israel Deaconess Hospital Corp. | Anti-angiogenic proteins and methods of use thereof |
| US6962974B1 (en) | 1998-06-17 | 2005-11-08 | Beth Israel Deaconess Medical Center | Anti-angiogenic proteins and fragments and methods of use thereof |
| US8128922B2 (en) | 1999-10-20 | 2012-03-06 | Johns Hopkins University | Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen |
| AU783662B2 (en) * | 2000-01-07 | 2005-11-24 | Beth Israel Deaconess Medical Center | Anti-angiogenic proteins and fragments and methods of use thereof |
| WO2001059112A1 (en) * | 2000-02-10 | 2001-08-16 | Zymogenetics, Inc. | Anti-angiogenic intestinal peptides, zdint5 |
| AU2001278117A1 (en) | 2000-08-03 | 2002-02-18 | Johns Hopkins University | Molecular vaccine linking an endoplasmic reticulum chaperone polypeptide to an antigen |
| US7175840B2 (en) | 2001-01-05 | 2007-02-13 | Viromed Co., Ltd. | Compositions for gene therapy of rheumatoid arthritis including a gene encoding an anti-angiogenic protein or parts thereof |
| BR0208880A (pt) * | 2001-04-13 | 2004-12-07 | Thompson Boyce Plant Res | Métodos para produzir um homogeneizado seco estável de uma planta transgênica que expressa uma proteìna heteróloga, para prevenir uma doença patogênica em um animal, para liberar uma proteìna transgênica a um animal, de contracepção e para induzir uma resposta imune mucosal, homogeneizado seco estável, composição farmacêutica, planta transgênica, célula de planta, vetor plasmìdico para transformar uma célula de planta, composição de alimento, e, alimento |
| CN100447155C (zh) * | 2001-05-23 | 2008-12-31 | 中国科学院上海上海生命科学研究院 | 具有抑制内皮细胞生长活性的重组人内皮生长抑制蛋白 |
| US7122517B2 (en) * | 2001-07-27 | 2006-10-17 | Kansas University Medical Center | Crystallized structure of type IV collagen NC1 domain hexamer |
| WO2004098526A2 (en) | 2003-05-05 | 2004-11-18 | Johns Hopkins University | Anti-cancer dna vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein |
| WO2006073970A2 (en) | 2005-01-06 | 2006-07-13 | The Johns Hopkins University | Rna interference that blocks expression of pro-apoptotic proteins potentiates immunity induced by dna and transfected dendritic cell vaccines |
| JP4843767B2 (ja) * | 2005-08-31 | 2011-12-21 | 国立大学法人 岡山大学 | がん細胞特異的遺伝子発現法を用いた血管新生阻害薬 |
| US9085638B2 (en) | 2007-03-07 | 2015-07-21 | The Johns Hopkins University | DNA vaccine enhancement with MHC class II activators |
| CN101962404A (zh) * | 2010-06-17 | 2011-02-02 | 中国热带农业科学院热带生物技术研究所 | 一种用于治疗血管瘤的蛋白质 |
| CN103998470A (zh) * | 2011-08-17 | 2014-08-20 | 科罗拉多大学董事会法人团体 | 运铁蛋白-肿瘤抑素融合蛋白质及其生成和使用方法 |
| ES2686968T3 (es) * | 2013-05-06 | 2018-10-23 | China Pharmaceutical University | Proteínas de fusión bifuncionales para inhibir la angiogénesis en el microambiente tumoral y para activar las respuestas inmunitarias adaptativas y los genes y usos de las mismas |
| CN111087477B (zh) * | 2020-01-03 | 2021-10-08 | 四川大学华西医院 | GBM-7S(α1)-NC1(α3)融合蛋白及其制备方法 |
| CN113735966B (zh) * | 2021-09-29 | 2022-11-01 | 陕西巨子生物技术有限公司 | 一种抗肿瘤重组胶原蛋白及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4876332A (en) * | 1987-10-08 | 1989-10-24 | Regents Of The Univeristy Of Minnesota | Polypeptides with type IV collagen activity |
| US5354690A (en) * | 1989-07-07 | 1994-10-11 | Karl Tryggvason | Immunological methods for the detection of the human type IV collagen α5 chain |
| US5114840A (en) * | 1989-07-07 | 1992-05-19 | Karl Tryggvason | Method for determining the nucleotide sequence of a novel α5(IV) chain of human type IV collagen |
| US5081031A (en) * | 1989-12-14 | 1992-01-14 | Regents Of The University Of Minnesota | Synthetic polypeptide with type iv collagen activity |
| US5082926A (en) * | 1989-12-14 | 1992-01-21 | Regents Of The University Of Minnesota | Polypeptide with type iv collagen cell adhesion, spreading and motility activity |
| US5424408A (en) * | 1990-11-30 | 1995-06-13 | Yale University | α-3 chain type IV collagen polynucleotides |
| US5731192A (en) * | 1993-08-27 | 1998-03-24 | Yale University | Collagen COL4A6: gene, protein and method of detecting collagen deficiency |
| US5567609A (en) * | 1994-06-30 | 1996-10-22 | University Of Kansas Medical Center | Use of isolated domains of type IV collagen to modify cell and tissue interactions |
-
1999
- 1999-06-17 IL IL14023999A patent/IL140239A0/xx unknown
- 1999-06-17 CN CN99808686A patent/CN1309663A/zh active Pending
- 1999-06-17 CA CA002331332A patent/CA2331332A1/en not_active Abandoned
- 1999-06-17 EP EP99928762A patent/EP1086129A1/en not_active Ceased
- 1999-06-17 AU AU45755/99A patent/AU753249B2/en not_active Ceased
- 1999-06-17 JP JP2000554765A patent/JP2002517999A/ja not_active Ceased
- 1999-06-17 WO PCT/US1999/013737 patent/WO1999065940A1/en active IP Right Grant
- 1999-06-17 KR KR1020007014426A patent/KR100682666B1/ko not_active IP Right Cessation
-
2007
- 2007-09-21 JP JP2007244618A patent/JP2008019271A/ja active Pending
-
2008
- 2008-06-24 JP JP2008164926A patent/JP2008301823A/ja active Pending