JP2002517228A - 異種ｇタンパク質共役受容体を発現する形質転換細胞株 - Google Patents

異種ｇタンパク質共役受容体を発現する形質転換細胞株

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Publication number
JP2002517228A
JP2002517228A JP2000553557A JP2000553557A JP2002517228A JP 2002517228 A JP2002517228 A JP 2002517228A JP 2000553557 A JP2000553557 A JP 2000553557A JP 2000553557 A JP2000553557 A JP 2000553557A JP 2002517228 A JP2002517228 A JP 2002517228A
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JP
Japan
Prior art keywords
receptor
gene
gpc
heterologous
cell line
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000553557A
Other languages
English (en)
Japanese (ja)
Inventor
ケッスマン，ヘルムート
ディーレンバーガー，フランツ
Original Assignee
ディスカバリー・テクノロジーズ・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by ディスカバリー・テクノロジーズ・リミテッド filed Critical ディスカバリー・テクノロジーズ・リミテッド
Publication of JP2002517228A publication Critical patent/JP2002517228A/ja
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2000553557A 1998-06-05 1999-06-04 異種ｇタンパク質共役受容体を発現する形質転換細胞株 Withdrawn JP2002517228A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH1226/98 1998-06-05
CH122698 1998-06-05
PCT/CH1999/000246 WO1999064567A1 (de) 1998-06-05 1999-06-04 Transformierte zell-linien, die heterologe g-protein-gekoppelte rezeptoren exprimieren

Publications (1)

Publication Number Publication Date
JP2002517228A true JP2002517228A (ja) 2002-06-18

Family

ID=4205446

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000553557A Withdrawn JP2002517228A (ja) 1998-06-05 1999-06-04 異種ｇタンパク質共役受容体を発現する形質転換細胞株

Country Status (5)

Country Link
EP (1) EP1084231A1 (de)
JP (1) JP2002517228A (de)
AU (1) AU4028199A (de)
CA (1) CA2334215A1 (de)
WO (1) WO1999064567A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1141397A1 (de) * 1998-12-22 2001-10-10 Isis Innovation Limited Verfahren für sequenz identifizierung
AU2012267241B2 (en) * 2011-06-10 2017-04-06 Temasek Life Sciences Laboratory Limited Genetic manipulation and expression systems for Pucciniomycotina and Ustilaginomycotina subphyla
CN113444724B (zh) * 2021-05-10 2023-03-17 西南大学 一种启动子及重组载体和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2628750B1 (fr) * 1988-03-21 1991-11-08 Pasteur Institut Vecteur modifie par une sequence codant pour une sequence d'acides amines contenue dans une proteine de mammifere ayant une activite biologique de recepteur membranaire
US5462856A (en) * 1990-07-19 1995-10-31 Bunsen Rush Laboratories, Inc. Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins
IE20020110A1 (en) * 1990-09-13 2003-05-28 Univ Duke Expression of G Protein Coupled Receptors in Yeast
CA2275465A1 (en) * 1996-12-27 1998-07-09 Merck & Co., Inc. Galanin receptor galr2 and nucleotides encoding same

Also Published As

Publication number Publication date
CA2334215A1 (en) 1999-12-16
AU4028199A (en) 1999-12-30
WO1999064567A1 (de) 1999-12-16
EP1084231A1 (de) 2001-03-21

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Effective date: 20060905