JP2002515043A5 - - Google Patents

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Publication number
JP2002515043A5
JP2002515043A5 JP1998508986A JP50898698A JP2002515043A5 JP 2002515043 A5 JP2002515043 A5 JP 2002515043A5 JP 1998508986 A JP1998508986 A JP 1998508986A JP 50898698 A JP50898698 A JP 50898698A JP 2002515043 A5 JP2002515043 A5 JP 2002515043A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998508986A
Other languages
English (en)
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JP2002515043A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/013008 external-priority patent/WO1998004913A1/en
Publication of JP2002515043A publication Critical patent/JP2002515043A/ja
Publication of JP2002515043A5 publication Critical patent/JP2002515043A5/ja
Ceased legal-status Critical Current

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Description

Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
Figure 2002515043
JP50898698A 1996-07-25 1997-07-24 Vla―4インヒビターのための分子モデル Ceased JP2002515043A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US2289096P 1996-07-25 1996-07-25
US60/022,890 1996-07-25
US3278696P 1996-12-06 1996-12-06
US60/032,786 1996-12-06
US5700297P 1997-06-30 1997-06-30
US60/057,002 1997-06-30
PCT/US1997/013008 WO1998004913A1 (en) 1996-07-25 1997-07-24 Molecular model for vla-4 inhibitors

Publications (2)

Publication Number Publication Date
JP2002515043A JP2002515043A (ja) 2002-05-21
JP2002515043A5 true JP2002515043A5 (ja) 2005-04-07

Family

ID=27361965

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50898698A Ceased JP2002515043A (ja) 1996-07-25 1997-07-24 Vla―4インヒビターのための分子モデル

Country Status (9)

Country Link
US (1) US6552216B1 (ja)
EP (1) EP0914605B1 (ja)
JP (1) JP2002515043A (ja)
AT (1) ATE363658T1 (ja)
CA (1) CA2261974A1 (ja)
DE (1) DE69737769T2 (ja)
DK (1) DK0914605T3 (ja)
ES (1) ES2285735T3 (ja)
HK (1) HK1020211A1 (ja)

Families Citing this family (10)

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Publication number Priority date Publication date Assignee Title
US6306840B1 (en) * 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
US6489300B1 (en) * 1997-07-31 2002-12-03 Eugene D. Thorsett Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4
US6939855B2 (en) * 1997-07-31 2005-09-06 Elan Pharmaceuticals, Inc. Anti-inflammatory compositions and method
JP4555468B2 (ja) * 1997-10-31 2010-09-29 アベンテイス・フアルマ・リミテツド 置換アニリド
US6407066B1 (en) 1999-01-26 2002-06-18 Elan Pharmaceuticals, Inc. Pyroglutamic acid derivatives and related compounds which inhibit leukocyte adhesion mediated by VLA-4
AU2002258794A1 (en) * 2001-04-10 2003-10-20 Transtech Pharma, Inc. Probes, systems and methods for drug discovery
JP2012501654A (ja) * 2008-09-05 2012-01-26 アビラ セラピューティクス, インコーポレイテッド 不可逆的インヒビターの設計のためのアルゴリズム
WO2011034907A2 (en) * 2009-09-16 2011-03-24 Avila Therapeutics, Inc. Protein kinase conjugates and inhibitors
CA2785738A1 (en) 2009-12-30 2011-07-07 Avila Therapeutics, Inc. Ligand-directed covalent modification of protein
BR112014009144A8 (pt) 2011-10-17 2017-06-20 Univ Muenster Westfaelische Wilhelms avaliação do risco de pml e métodos com base na mesma

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1149971B (it) 1979-06-11 1986-12-10 Syntex Inc Derivati nonapeptide e decapeptide dell'ormone che rilascia l'ormone luteinizzante
US4725583A (en) 1985-01-23 1988-02-16 Abbott Laboratories Functionalized peptidylaminoalcohols
US4826815A (en) 1985-05-17 1989-05-02 Abbott Laboratories Renin inhibiting compounds
DK163689A (da) 1988-04-08 1989-10-30 Sandoz Ag Peptidderivater
US4908360A (en) 1988-11-14 1990-03-13 Hoechst-Roussel Pharmaceuticals Inc. 1-aminoalkyl-3-oxysubstituted-4-aryl-1,3,4,5-tetrahydro-2H-1,3-benzodiazepine-2-ones
WO1991009837A1 (en) 1989-12-22 1991-07-11 Commonwealth Scientific And Industrial Research Organisation Amino acids, peptides or derivatives thereof coupled to fats
CA2043741C (en) 1990-06-07 2003-04-01 Kiyofumi Ishikawa Endothelin antagonistic peptide derivatives
US5192746A (en) 1990-07-09 1993-03-09 Tanabe Seiyaku Co., Ltd. Cyclic cell adhesion modulation compounds
US5260277A (en) 1990-09-10 1993-11-09 Tanabe Seiyaku Co., Ltd. Guanidinyl and related cell adhesion modulation compounds
WO1992008464A1 (en) 1990-11-15 1992-05-29 Tanabe Seiyaku Co. Ltd. Substituted urea and related cell adhesion modulation compounds
EP0519748B1 (en) 1991-06-21 1998-09-02 Merck & Co. Inc. Peptidyl derivatives as inhibitors of interleukin-1B converting enzyme
US5250679A (en) 1991-10-18 1993-10-05 Genentech, Inc. Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
WO1993008823A1 (en) 1991-11-06 1993-05-13 Tanabe Seiyaku Co., Ltd. Guanidinyl and related cell adhesion modulation compounds
EP0617705B1 (en) 1991-11-22 1997-09-24 Yeda Research And Development Company, Ltd. Non-peptidic surrogates of the arg-gly-asp sequence and pharmaceutical compositions comprising them
AU3420693A (en) 1991-12-24 1993-07-28 Fred Hutchinson Cancer Research Center Competitive inhibition of high-avidity alpha4-beta1 receptor using tripeptide ldv
DE4212304A1 (de) 1992-04-13 1993-10-14 Cassella Ag Asparaginsäurederivate, ihre Herstellung und Verwendung
IL102646A (en) 1992-07-26 1996-05-14 Yeda Res & Dev Non-peptidic surrogates of the ldv sequence and pharmaceutical compositions comprising them
WO1994015958A2 (en) 1993-01-08 1994-07-21 Tanabe Seiyaku Co., Ltd. Peptide inhibitors of cell adhesion
US5314902A (en) 1993-01-27 1994-05-24 Monsanto Company Urea derivatives useful as platelet aggregation inhibitors
DE4309867A1 (de) 1993-03-26 1994-09-29 Cassella Ag Neue Harnstoffderivate, ihre Herstellung und Verwendung
KR960701633A (ko) 1993-04-09 1996-03-28 가쯔히꼬 나까노 면역조절제, 세포 접착 억제제, 및 자기면역 질병의 치료 및 예방제(immunomo-dulator, cell adhesion inhibitor, and agent for treating and preventing autoimmune diseases)
AU693143B2 (en) 1993-12-06 1998-06-25 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
US5770573A (en) 1993-12-06 1998-06-23 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
US5434188A (en) 1994-03-07 1995-07-18 Warner-Lambert Company 1-ether and 1-thioether-naphthalene-2-carboxamides as inhibitors of cell adhesion and as inhibitors of the activation of HIV
US6306840B1 (en) 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
US6239108B1 (en) 1996-07-11 2001-05-29 Biogen, Inc. Cell adhesion inhibitors

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