JP2002515019A5 - - Google Patents
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- Publication number
- JP2002515019A5 JP2002515019A5 JP1997502307A JP50230797A JP2002515019A5 JP 2002515019 A5 JP2002515019 A5 JP 2002515019A5 JP 1997502307 A JP1997502307 A JP 1997502307A JP 50230797 A JP50230797 A JP 50230797A JP 2002515019 A5 JP2002515019 A5 JP 2002515019A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/487,443 | 1995-06-07 | ||
| US08/483,057 | 1995-06-07 | ||
| US08/479,455 | 1995-06-07 | ||
| US08/475,572 US5840936A (en) | 1995-06-07 | 1995-06-07 | Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE) |
| US08/483,059 | 1995-06-07 | ||
| US08/487,443 US5847172A (en) | 1995-06-07 | 1995-06-07 | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
| US08/476,855 | 1995-06-07 | ||
| US08/479,457 | 1995-06-07 | ||
| US08/475,572 | 1995-06-07 | ||
| US08/476,855 US5874597A (en) | 1995-06-07 | 1995-06-07 | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
| US08/483,057 US5795885A (en) | 1995-06-07 | 1995-06-07 | Method of inhibiting profileration of cells by administering an aminosterol compound |
| US08/483,059 US5840740A (en) | 1995-06-07 | 1995-06-07 | Aminosterol compounds and a method of treating infection using the aminosterol compounds |
| US08/479,455 US5994336A (en) | 1995-06-07 | 1995-06-07 | Method of inhibiting proliferation of cells by administering an aminosterol compound |
| US08/479,457 US5763430A (en) | 1995-06-07 | 1995-06-07 | Method of treating a viral infection by administering a steroid compound |
| PCT/US1996/010508 WO1996040728A2 (en) | 1995-06-07 | 1996-06-07 | Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (nhe), pharmaceutical methods and compositions employing such inhibitors, and processes for evaluating the nhe-inhibitory efficacy of compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007223309A Division JP2007314577A (ja) | 1995-06-07 | 2007-08-29 | ナトリウム／プロトン交換体（ｎｈｅ）の阻害剤として有用なアミノステロール化合物、同阻害剤を使用する薬学的方法および組成物、ならびに化合物のｎｈｅ阻害効果を評価する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002515019A JP2002515019A (ja) | 2002-05-21 |
| JP2002515019A5 true JP2002515019A5 (https=) | 2004-07-29 |
| JP4104164B2 JP4104164B2 (ja) | 2008-06-18 |
Family
ID=27569803
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50230797A Expired - Lifetime JP4104164B2 (ja) | 1995-06-07 | 1996-06-07 | ナトリウム／プロトン交換体（ｎｈｅ）の阻害剤として有用なアミノステロール化合物、同阻害剤を使用する薬学的方法および組成物、ならびに化合物のｎｈｅ阻害効果を評価する方法 |
| JP2007223309A Withdrawn JP2007314577A (ja) | 1995-06-07 | 2007-08-29 | ナトリウム／プロトン交換体（ｎｈｅ）の阻害剤として有用なアミノステロール化合物、同阻害剤を使用する薬学的方法および組成物、ならびに化合物のｎｈｅ阻害効果を評価する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007223309A Withdrawn JP2007314577A (ja) | 1995-06-07 | 2007-08-29 | ナトリウム／プロトン交換体（ｎｈｅ）の阻害剤として有用なアミノステロール化合物、同阻害剤を使用する薬学的方法および組成物、ならびに化合物のｎｈｅ阻害効果を評価する方法 |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP0832094B1 (https=) |
| JP (2) | JP4104164B2 (https=) |
| AT (1) | ATE259375T1 (https=) |
| AU (1) | AU723663C (https=) |
| CA (1) | CA2223910C (https=) |
| DE (1) | DE69631527T2 (https=) |
| DK (1) | DK0832094T3 (https=) |
| ES (1) | ES2216049T3 (https=) |
| PT (1) | PT832094E (https=) |
| WO (1) | WO1996040728A2 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5856535A (en) * | 1994-08-18 | 1999-01-05 | Magainin Pharmaceuticals, Inc. | Aminosterol ester compounds |
| US5792635A (en) * | 1995-06-07 | 1998-08-11 | Magainin Pharmaceuticals, Inc. | Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine |
| US6143738A (en) * | 1995-06-07 | 2000-11-07 | Magainin Pharmaceuticals, Inc. | Therapeutic uses for an aminosterol compound |
| ES2201296T3 (es) * | 1996-04-26 | 2004-03-16 | Genaera Corporation | Escualmina en combinacion con otros farmacos anticancerigenos para el tratamiento de tumores. |
| US6596712B2 (en) | 1996-04-26 | 2003-07-22 | Genaera Corporation | Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities |
| EP0923377A1 (en) * | 1996-05-17 | 1999-06-23 | Magainin Pharmaceuticals Inc. | Therapeutic uses for an aminosterol compound |
| US7410959B1 (en) * | 2000-07-13 | 2008-08-12 | Genaera Corporation | Therapeutic uses for aminosterol compounds |
| AU5194998A (en) * | 1996-11-01 | 1998-05-29 | Magainin Pharmaceuticals, Inc. | Certain aminosterol compounds and uses therefor |
| US6262283B1 (en) * | 1996-12-06 | 2001-07-17 | Magainin Pharmaceuticals Inc. | Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds |
| DE19737463A1 (de) * | 1997-08-28 | 1999-03-04 | Hoechst Marion Roussel De Gmbh | Verwendung von Inhibitoren des Natrium-Wasserstoff-Austauschers zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die durch Protozoen verursacht werden |
| PT1274718E (pt) | 2000-04-12 | 2007-01-31 | Genaera Corp | Processo para a preparação de esteróis 7. alfa-hidroxi 3- aminosubstítuidos utilizando intermediários com um grupo 7. alfa-hidroxilo desprotegido |
| WO2006119211A2 (en) * | 2005-05-02 | 2006-11-09 | Genaera Corporation | Methods and compositions for treating ocular disorders |
| US20080058300A1 (en) * | 2006-04-21 | 2008-03-06 | Mclane Michael | Induction of weight loss and the selective inhibition of PTP1B |
| JP2010538072A (ja) * | 2007-09-06 | 2010-12-09 | ジェナエラ コーポレイション | 糖尿病を治療する方法 |
| AU2009243749B2 (en) * | 2008-05-09 | 2013-11-21 | Merck Patent Gmbh | Pharmaceutical composition comprising rimeporide for treating diseases associated with insulin resistance and beta-cell dysfunction |
| BR112014003704A2 (pt) * | 2011-09-19 | 2017-03-07 | Eth Zuerich | moduladores ror gama |
| ES2736310T3 (es) * | 2012-04-20 | 2019-12-27 | Ohr Pharmaceutical Inc | Aminoesteroides para el tratamiento de una enfermedad asociada a PTP1B |
| WO2014151411A1 (en) | 2013-03-15 | 2014-09-25 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
| US11524015B2 (en) | 2013-03-15 | 2022-12-13 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
| EP2781217A1 (en) * | 2013-03-18 | 2014-09-24 | ETH Zurich | ROR gamma modulators |
| US10040817B2 (en) * | 2013-10-03 | 2018-08-07 | Enterin Laboratories, Inc. | Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same |
| US11690855B2 (en) | 2013-10-17 | 2023-07-04 | Brigham Young University | Methods for treating lung infections and inflammation |
| US20150203527A1 (en) | 2014-01-23 | 2015-07-23 | Brigham Young University | Cationic steroidal antimicrobials |
| US10441595B2 (en) * | 2014-06-26 | 2019-10-15 | Brigham Young University | Methods for treating fungal infections |
| FR3033563B1 (fr) * | 2015-03-12 | 2018-04-13 | Virbac | Composes analogues de la squalamine utiles comme agents antibacteriens |
| FR3055801B1 (fr) * | 2016-09-15 | 2020-10-30 | Virbac | Derives esters de squalamine pour le traitement des infections |
| MA50094A (fr) * | 2017-09-08 | 2020-07-15 | Enterin Inc | Méthodes de traitement des troubles du sommeil, des perturbations du sommeil et de symptômes associés à l'aide de compositions d'aminostérol |
| EP3829587A4 (en) * | 2018-08-03 | 2022-07-20 | Enterin, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF BRAIN AND GUESS DISORDERS |
| US11464789B2 (en) | 2018-08-03 | 2022-10-11 | Enterin, Inc. | Aminosterol compositions and methods of using the same for treating schizophrenia |
| US12186328B2 (en) | 2019-05-23 | 2025-01-07 | Brigham Young University | Use of CSA compounds to stimulate stem cells and hair growth |
| WO2021025974A1 (en) * | 2019-08-02 | 2021-02-11 | Enterin, Inc. | Human squalamine derivatives, related compositions comprising the same, and methods of using the same |
| EP4007764B1 (en) | 2019-08-02 | 2026-01-21 | Enterin, Inc. | Human aminosterol ent-03 compounds, related compositions comprising the same, and methods of using the same |
| CN112782300B (zh) * | 2020-12-25 | 2022-04-12 | 山东省食品药品检验研究院 | 一种胆烷酸的同分异构体及其检测方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192756A (en) * | 1992-03-18 | 1993-03-09 | The Children's Hospital Of Pennsylvania | Aminosterol antibiotic |
| WO1994019366A1 (en) * | 1993-02-26 | 1994-09-01 | Magainin Pharmaceuticals Inc. | Chemical synthesis of squalamine |
| DE69412596T2 (de) * | 1993-03-10 | 1999-03-04 | Magainin Pharmaceuticals Inc., Plymouth Meeting, Pa. | Steroidderivate, pharmazeutische zusammensetzungen die sie enthalten und ihre verwendung als antibiotika oder desinfektionsmittel |
-
1996
- 1996-06-07 AT AT96922490T patent/ATE259375T1/de not_active IP Right Cessation
- 1996-06-07 AU AU63349/96A patent/AU723663C/en not_active Ceased
- 1996-06-07 EP EP96922490A patent/EP0832094B1/en not_active Expired - Lifetime
- 1996-06-07 DE DE69631527T patent/DE69631527T2/de not_active Expired - Lifetime
- 1996-06-07 CA CA002223910A patent/CA2223910C/en not_active Expired - Lifetime
- 1996-06-07 DK DK96922490T patent/DK0832094T3/da active
- 1996-06-07 JP JP50230797A patent/JP4104164B2/ja not_active Expired - Lifetime
- 1996-06-07 ES ES96922490T patent/ES2216049T3/es not_active Expired - Lifetime
- 1996-06-07 PT PT96922490T patent/PT832094E/pt unknown
- 1996-06-07 WO PCT/US1996/010508 patent/WO1996040728A2/en not_active Ceased
- 1996-06-07 EP EP04002943A patent/EP1420027A3/en not_active Withdrawn
-
2007
- 2007-08-29 JP JP2007223309A patent/JP2007314577A/ja not_active Withdrawn