|
US6184344B1
(en)
*
|
1995-05-04 |
2001-02-06 |
The Scripps Research Institute |
Synthesis of proteins by native chemical ligation
|
|
US6849428B1
(en)
*
|
1997-03-05 |
2005-02-01 |
New England Biolabs, Inc. |
Intein-mediated protein ligation of expressed proteins
|
|
EP1001968B1
(en)
*
|
1997-06-13 |
2004-12-22 |
Gryphon Therapeutics, Inc. |
Solid phase native chemical ligation of unprotected or n-terminal cysteine protected peptides in aqueous solution
|
|
WO1999011655A1
(en)
*
|
1997-09-04 |
1999-03-11 |
Gryphon Sciences |
Modular protein libraries and methods of preparation
|
|
AUPP589598A0
(en)
|
1998-09-14 |
1998-10-08 |
University Of Queensland, The |
Novel peptides
|
|
US7001745B1
(en)
*
|
1998-09-30 |
2006-02-21 |
New England Biolabs, Inc. |
Intein mediated peptide ligation
|
|
AU768118B2
(en)
*
|
1999-03-11 |
2003-12-04 |
Gryphon Sciences |
Chemical synthesis and use of soluble membrane protein receptor domains
|
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
AU2001284853A1
(en)
*
|
2000-08-11 |
2002-02-25 |
Invitrogen Corporation |
Highly homogeneous molecular markers for electrophoresis
|
|
US20040014082A1
(en)
*
|
2000-08-11 |
2004-01-22 |
Invitrogen Corporation |
Highly homogeneous molecular markers for electrophoresis
|
|
JP2004507557A
(ja)
*
|
2000-09-01 |
2004-03-11 |
グリフォン セラピューティクス，インコーポレーテッド |
求核物質に対して安定なチオエステル生成化合物、製造および使用の方法
|
|
CA2435394C
(en)
*
|
2001-01-22 |
2018-01-09 |
Sangamo Biosciences, Inc. |
Modified zinc finger binding proteins
|
|
DE60216468T2
(de)
*
|
2001-03-09 |
2007-09-27 |
Boston Probes, Inc., Bedford |
Kombinationsoligomere betreffende verfahren, kits und zusammensetzungen
|
|
GB0113657D0
(en)
*
|
2001-06-05 |
2001-07-25 |
Geneprot Inc |
Improved native chemical ligation with three or more components
|
|
EP2042196B1
(en)
|
2001-10-10 |
2016-07-13 |
ratiopharm GmbH |
Remodelling and glycoconjugation of Granulocyte Colony Stimulating Factor (G-CSF)
|
|
WO2003106615A2
(en)
*
|
2002-06-10 |
2003-12-24 |
Geneprot, Inc. |
Post-cleavage sulfur deprotection for convergent protein synthesis by chemical ligation
|
|
AU2002328824A1
(en)
*
|
2002-06-29 |
2004-01-19 |
Aquanova German Solubilisate Technologies (Agt) Gmbh |
Isoflavone concentrate and method for production thereof
|
|
US7166574B2
(en)
*
|
2002-08-20 |
2007-01-23 |
Biosurface Engineering Technologies, Inc. |
Synthetic heparin-binding growth factor analogs
|
|
US7598224B2
(en)
*
|
2002-08-20 |
2009-10-06 |
Biosurface Engineering Technologies, Inc. |
Dual chain synthetic heparin-binding growth factor analogs
|
|
US8227411B2
(en)
|
2002-08-20 |
2012-07-24 |
BioSurface Engineering Technologies, Incle |
FGF growth factor analogs
|
|
US7981862B2
(en)
|
2003-08-19 |
2011-07-19 |
Biosurface Engineering Technologies, Inc. |
Composition comprising BMP-2 amplifier/co-activator for enhancement of osteogenesis
|
|
AU2003300859A1
(en)
*
|
2002-12-11 |
2004-06-30 |
New England Biolabs, Inc. |
Carrier-ligand fusions and uses thereof
|
|
WO2004061094A1
(en)
|
2002-12-30 |
2004-07-22 |
Gryphon Therapeutics, Inc. |
Water-soluble thioester and selenoester compounds and methods for making and using the same
|
|
NZ542586A
(en)
|
2003-04-09 |
2009-11-27 |
Biogenerix Ag |
Method of forming a covalent conjugate between a G-CSF peptide and PEG
|
|
ES2333598T5
(es)
*
|
2003-05-06 |
2013-09-04 |
Biogen Idec Hemophilia Inc |
Proteinas quimericas del factor de coagulacion fc para tratar la hemofilia.
|
|
US7348004B2
(en)
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
|
WO2004105685A2
(en)
*
|
2003-05-22 |
2004-12-09 |
Gryphon Therapeutics, Inc. |
Displaceable linker solid phase chemical ligation
|
|
US7414028B1
(en)
|
2004-02-04 |
2008-08-19 |
Biosurface Engineering Technologies, Inc. |
Growth factor analogs
|
|
US7528105B1
(en)
|
2004-02-10 |
2009-05-05 |
Biosurface Engineering Technologies |
Heterodimeric chain synthetic heparin-binding growth factor analogs
|
|
US20080227696A1
(en)
|
2005-02-22 |
2008-09-18 |
Biosurface Engineering Technologies, Inc. |
Single branch heparin-binding growth factor analogs
|
|
US7671012B2
(en)
|
2004-02-10 |
2010-03-02 |
Biosurface Engineering Technologies, Inc. |
Formulations and methods for delivery of growth factor analogs
|
|
US20060024347A1
(en)
*
|
2004-02-10 |
2006-02-02 |
Biosurface Engineering Technologies, Inc. |
Bioactive peptide coatings
|
|
DE602005023714D1
(de)
|
2004-02-20 |
2010-11-04 |
Biosurface Eng Tech Inc |
Positiver modulator des knochenmorphogenetisches protein-2 (bmp-2)
|
|
UA88008C2
(en)
|
2004-04-09 |
2009-09-10 |
Чугей Сейяку Кабусики Кайся |
Water-soluble prodrugs
|
|
EP1749022A2
(en)
*
|
2004-05-24 |
2007-02-07 |
Rigel Pharmaceuticals, Inc. |
Methods for cyclizing synthetic polymers
|
|
US7671023B2
(en)
|
2005-03-31 |
2010-03-02 |
Amylin Pharmaceuticals, Inc. |
Amylin agonist for treating depression, anxiety disorder and schizophrenia
|
|
TW200744603A
(en)
|
2005-08-22 |
2007-12-16 |
Chugai Pharmaceutical Co Ltd |
Novel anticancer concomitant drug
|
|
US7674881B2
(en)
*
|
2005-10-07 |
2010-03-09 |
The University Of Chicago |
Convergent synthesis of proteins by kinetically controlled ligation
|
|
KR20080066039A
(ko)
*
|
2005-10-19 |
2008-07-15 |
추가이 세이야쿠 가부시키가이샤 |
신규 수용성 프로드러그를 함유하는 췌장암, 난소암 또는 간암의 예방 또는 치료제
|
|
US7820172B1
(en)
|
2006-06-01 |
2010-10-26 |
Biosurface Engineering Technologies, Inc. |
Laminin-derived multi-domain peptides
|
|
WO2008097536A2
(en)
|
2007-02-05 |
2008-08-14 |
Amylin Pharmaceuticals, Inc. |
Compositions and methods for treating psychiatric diseases and disorders
|
|
US8404804B2
(en)
*
|
2007-08-28 |
2013-03-26 |
Ipsen Pharma S.A.S. |
Methods and intermediates for chemical synthesis of polypeptides and proteins
|
|
WO2011103409A1
(en)
*
|
2010-02-18 |
2011-08-25 |
Advanced Proteome Therapeutics Inc. |
Site-specific modification of proteins through chemical modification enabling protein conjugates, protein dimer formation, and stapled peptides
|
|
EA201390450A1
(ru)
|
2010-09-28 |
2013-07-30 |
Амилин Фармасьютикалс, Ллк. |
Полипептиды с увеличенной продолжительностью действия
|
|
JP2014502252A
(ja)
|
2010-09-28 |
2014-01-30 |
アミリン・ファーマシューティカルズ，リミテッド・ライアビリティ・カンパニー |
作用持続時間が増した改変ポリペプチド
|
|
JP6006309B2
(ja)
|
2011-07-08 |
2016-10-12 |
アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc |
作用持続期間が増大し、免疫原性が減少した操作されたポリペプチド
|
|
ES2732475T3
(es)
|
2011-07-08 |
2019-11-22 |
Aegerion Pharmaceuticals Inc |
Polipéptidos modificados por ingeniería genética que tienen una duración potenciada de la acción y una inmunogenicidad reducida
|
|
FR2981352B1
(fr)
*
|
2011-10-17 |
2015-07-03 |
Centre Nat Rech Scient |
Procede de synthese de proteines
|
|
JP6290187B2
(ja)
|
2012-05-11 |
2018-03-07 |
クランツ，アレクサンダー |
癌の処置のためのタンパク質の部位特異的標識及び標的送達
|
|
JP2015519344A
(ja)
|
2012-05-21 |
2015-07-09 |
マサチューセッツ インスティテュート オブ テクノロジー |
炭疽菌防御抗原ポアを通しての非天然化学実体のトランスロケーション
|
|
TWI828269B
(zh)
|
2013-03-15 |
2024-01-01 |
美商百歐維拉提夫治療公司 |
因子ix多肽調配物
|
|
US11273176B2
(en)
|
2016-03-02 |
2022-03-15 |
The Brigham And Women's Hospital, Inc. |
Use of PLA2G5-deficient suppressive macrophages in suppression of inflammation
|
|
JP7067798B2
(ja)
*
|
2017-03-02 |
2022-05-16 |
株式会社糖鎖工学研究所 |
アミノ酸ポリマーの製造方法
|
|
WO2020070587A1
(en)
|
2018-10-01 |
2020-04-09 |
Université De Genève |
Methods for producing a plurality of polypeptide variants suitable for biological analysis
|
|
WO2020110330A1
(ja)
*
|
2018-11-30 |
2020-06-04 |
株式会社糖鎖工学研究所 |
ペプチドチオエステル、ペプチドの新規製造方法
|
|
AU2020361681A1
(en)
|
2019-10-10 |
2022-05-05 |
1859, Inc. |
Methods and systems for microfluidic screening
|
|
EP3838913A4
(en)
*
|
2019-10-23 |
2021-11-03 |
MabPlex International Co., Ltd. |
OLIGOPEPTIDE LINKER INTERMEDIATE AND MANUFACTURING PROCESS FOR IT
|
|
WO2022266467A2
(en)
|
2021-06-17 |
2022-12-22 |
Dana-Farber Cancer Institute, Inc. |
Recombinant histone polypeptide and uses thereof
|
|
WO2024146707A1
(en)
|
2023-01-06 |
2024-07-11 |
Université De Genève |
Variant ligand conjugates for payload delivery
|