JP2002501484A5 - - Google Patents
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- Publication number
- JP2002501484A5 JP2002501484A5 JP1998538801A JP53880198A JP2002501484A5 JP 2002501484 A5 JP2002501484 A5 JP 2002501484A5 JP 1998538801 A JP1998538801 A JP 1998538801A JP 53880198 A JP53880198 A JP 53880198A JP 2002501484 A5 JP2002501484 A5 JP 2002501484A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3998797P | 1997-03-05 | 1997-03-05 | |
| US60/039,987 | 1997-03-05 | ||
| PCT/US1998/004303 WO1998039363A2 (en) | 1997-03-05 | 1998-03-05 | Immunotoxins and methods of inducing immune tolerance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002501484A JP2002501484A (ja) | 2002-01-15 |
| JP2002501484A5 true JP2002501484A5 (https=) | 2005-11-10 |
Family
ID=21908461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53880198A Ceased JP2002501484A (ja) | 1997-03-05 | 1998-03-05 | 免疫毒素および免疫寛容を誘導する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6632928B1 (https=) |
| EP (1) | EP1015496B1 (https=) |
| JP (1) | JP2002501484A (https=) |
| AT (1) | ATE433998T1 (https=) |
| AU (1) | AU733898B2 (https=) |
| CA (1) | CA2284079C (https=) |
| DE (1) | DE69840913D1 (https=) |
| WO (1) | WO1998039363A2 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7288254B2 (en) | 1995-10-30 | 2007-10-30 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services, Nih | Use of immunotoxins to induce immune tolerance to pancreatic islet transplantation |
| US7696338B2 (en) | 1995-10-30 | 2010-04-13 | The United States Of America As Represented By The Department Of Health And Human Services | Immunotoxin fusion proteins and means for expression thereof |
| US7517527B2 (en) | 1995-10-30 | 2009-04-14 | The United States Of America As Represented By The Department Of Health And Human Services | Immunotoxin with in vivo T cell suppressant activity and methods of use |
| US7125553B1 (en) | 1996-04-15 | 2006-10-24 | The United States of America as represented by the Department of Health and Human Services c/o Centers for Disease Control and Prevention | Methods of inducing immune tolerance using immunotoxins |
| EP1015496B1 (en) | 1997-03-05 | 2009-06-17 | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Divalent anti-t cells immunotoxins and use thereof |
| EP1144010B1 (en) * | 1999-01-08 | 2007-04-18 | Wisconsin Alumni Research Foundation | Prevention of chronic graft rejection by a combination of immunotoxins and costimulation blockers |
| US20020142000A1 (en) * | 1999-01-15 | 2002-10-03 | Digan Mary Ellen | Anti-CD3 immunotoxins and therapeutic uses therefor |
| AU781547B2 (en) * | 1999-04-14 | 2005-05-26 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Compositions containing immunotoxins and agents that inhibit dendritic cell maturation for inducing immune tolerance to a graft |
| AU783250B2 (en) * | 1999-06-17 | 2005-10-06 | Dartmouth College | Autologous adoptive immunotherapy with primed antigen-specific T cells or B cells |
| US6492498B1 (en) | 1999-11-15 | 2002-12-10 | Regents Of The University Of Minnesota | Multimeric immunotoxins |
| CA2409746C (en) * | 2000-05-18 | 2014-11-25 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Immunotoxin fusion proteins and means for expression thereof |
| CN101812133A (zh) * | 2001-07-24 | 2010-08-25 | 德拜奥维森公司 | 受体、其应用以及小鼠抗体 |
| US20050069549A1 (en) | 2002-01-14 | 2005-03-31 | William Herman | Targeted ligands |
| US7105347B2 (en) | 2002-07-30 | 2006-09-12 | Corning Incorporated | Method and device for protein delivery into cells |
| US7691580B2 (en) * | 2003-01-29 | 2010-04-06 | Corning Incorporated | Reverse protein delivery into cells on coded microparticles |
| US20090029460A1 (en) * | 2004-01-26 | 2009-01-29 | Peter Vollmers | Neoplasm-specific polypeptides and their uses |
| WO2008020827A2 (en) * | 2005-08-01 | 2008-02-21 | Biogen Idec Ma Inc. | Altered polypeptides, immunoconjugates thereof, and methods related thereto |
| CA2626547A1 (en) * | 2005-10-21 | 2007-05-03 | Medical College Of Georgia Research Institute, Inc. | The induction of indoleamine 2,3-dioxygenase in dendritic cells by tlr ligands and uses thereof |
| PE20081140A1 (es) | 2006-10-25 | 2008-09-22 | Amgen Inc | Agentes terapeuticos a base de peptidos derivados de toxinas |
| EP2162540A2 (en) | 2007-05-22 | 2010-03-17 | Amgen Inc. | Compositions and methods for producing bioactive fusion proteins |
| PL2197903T3 (pl) * | 2007-09-04 | 2015-03-31 | Us Gov Health & Human Services | Delecje w domenie ii egzotoksyny a psuedomonas zmniejszające toksyczność niespecyficzną |
| ES2534085T3 (es) | 2009-08-17 | 2015-04-17 | Roche Glycart Ag | Inmunoconjugados dirigidos |
| EP2565667A1 (en) | 2011-08-31 | 2013-03-06 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Direction of arrival estimation using watermarked audio signals and microphone arrays |
| WO2025050404A1 (zh) * | 2023-09-08 | 2025-03-13 | 成都维瑾柏鳌生物医药科技有限公司 | 一种药物组合物及其应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4520226A (en) | 1982-07-19 | 1985-05-28 | The United States Of America As Represented By The Department Of Health And Human Services | Treatment of graft versus host disease using a mixture of T-lymphocyte specific monoclonal antibody: ricin conjugates |
| DE3689620T2 (de) | 1985-11-13 | 1994-06-16 | Univ Hospital Boston | Durch cys-kodon modifizierte dns. |
| US4981979A (en) | 1987-09-10 | 1991-01-01 | Neorx Corporation | Immunoconjugates joined by thioether bonds having reduced toxicity and improved selectivity |
| JPH03503887A (ja) | 1988-02-03 | 1991-08-29 | エクソウマ コーポレーション | 自己免疫疾患に対する抗ｔ細胞イムノトキシンの治療的使用 |
| IL89504A0 (en) | 1988-03-08 | 1989-09-10 | Univ Wyoming | Diphtheria toxin derivative,process for the preparation thereof and pharmaceutical composition containing the same |
| US5980896A (en) * | 1989-06-30 | 1999-11-09 | Bristol-Myers Squibb Company | Antibodies reactive with human carcinomas |
| EP0517751A4 (en) | 1990-02-26 | 1993-03-31 | Commonwealth Scientific & Industrial Research Organisation ( C.S.I.R.O. ) | Shuttle plasmid for escherichia coli and mycobacteria |
| US5725857A (en) | 1991-02-11 | 1998-03-10 | The United States Of America As Represented By The Department Of Health And Human Services | Immunotoxin with in vivo T cell suppressant activity and methods of use |
| US5167956A (en) | 1991-02-11 | 1992-12-01 | The United States Of America As Represented By The Department Of Health And Human Services | Immunotoxin with in-vivo t cell suppressant activity |
| WO1993015113A1 (en) | 1992-01-24 | 1993-08-05 | Tanox Biosystems, Inc. | An immunotoxin including a cytotoxin with an unpaired cysteine residue in or near its receptor-binding site |
| DK0616034T3 (da) | 1993-03-05 | 2005-02-21 | Wyeth Corp | Plasmid til fremstilling af CRM-protein og diphtheria toxin |
| US5917017A (en) | 1994-06-08 | 1999-06-29 | President And Fellows Of Harvard College | Diphtheria toxin vaccines bearing a mutated R domain |
| US5688781A (en) | 1994-08-19 | 1997-11-18 | Bristol-Myers Squibb Company | Method for treating vascular leak syndrome |
| CA2218166C (en) * | 1995-04-14 | 2012-08-14 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Methods of inducing immune tolerance using immunotoxins |
| US6103235A (en) | 1995-10-30 | 2000-08-15 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of inducing immune tolerance using immunotoxins |
| US5747474A (en) * | 1996-07-29 | 1998-05-05 | Immune Modulation, Inc. | Immunosuppression by administration of N6,N6 -disubstituted cAMP's, analogues thereof, and related nucleosides |
| EP1015496B1 (en) | 1997-03-05 | 2009-06-17 | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Divalent anti-t cells immunotoxins and use thereof |
| EP0968282A2 (en) | 1997-03-05 | 2000-01-05 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Vectors and methods for expression of mutant proteins |
| US5801193A (en) * | 1997-04-15 | 1998-09-01 | Immune Modulation, Inc. | Compositions and methods for immunosuppressing |
| AU3654499A (en) | 1998-04-22 | 1999-11-08 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Use of immunotoxins to induce immune tolerance to pancreatic islet transplantation |
| EP1144010B1 (en) | 1999-01-08 | 2007-04-18 | Wisconsin Alumni Research Foundation | Prevention of chronic graft rejection by a combination of immunotoxins and costimulation blockers |
| US20020142000A1 (en) | 1999-01-15 | 2002-10-03 | Digan Mary Ellen | Anti-CD3 immunotoxins and therapeutic uses therefor |
| AU781547B2 (en) | 1999-04-14 | 2005-05-26 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Compositions containing immunotoxins and agents that inhibit dendritic cell maturation for inducing immune tolerance to a graft |
-
1998
- 1998-03-05 EP EP98911483A patent/EP1015496B1/en not_active Expired - Lifetime
- 1998-03-05 US US09/380,484 patent/US6632928B1/en not_active Expired - Lifetime
- 1998-03-05 JP JP53880198A patent/JP2002501484A/ja not_active Ceased
- 1998-03-05 WO PCT/US1998/004303 patent/WO1998039363A2/en not_active Ceased
- 1998-03-05 CA CA002284079A patent/CA2284079C/en not_active Expired - Lifetime
- 1998-03-05 AU AU65426/98A patent/AU733898B2/en not_active Expired
- 1998-03-05 AT AT98911483T patent/ATE433998T1/de not_active IP Right Cessation
- 1998-03-05 DE DE69840913T patent/DE69840913D1/de not_active Expired - Lifetime
-
2003
- 2003-05-09 US US10/435,567 patent/US20030185825A1/en not_active Abandoned