JP2002138031A - Bathing agent - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a bathing agent capable of enhancing refreshing feeling while lowering sticky feeling after bathing, exhibiting an antiinflammatory effects due to a calcium silicate contained in a freez-dried salt, and exhibiting also a curing effect on atopic dermatitis, or the like. SOLUTION: This bathing agent is that incorporating lyophilized salts 9 from sea water as the new material. The bathing agent stands on the basis that it exhibits an antiinflammatory action due to a calcium silicate contained in the lyophilized salts 9 by incorporating the salts 9 from sea water as the raw material into a liquid. As the liquid, one or plural kinds of original deep ocean sea water, its condensate, city water, mineral spring water are used. Those lyophilized salts obtained from deep ocean sea water are used for the above lyophilized salts 9 to be incorporates into the liquid.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001] The present invention relates to a bath preparation, and in particular, by incorporating a lyophilized salt from seawater as a raw material in the bath preparation, effectively inhibits the inflammation-suppressing action of the calcium silicate salt contained in the lyophilized salt. It relates to the bath salt used in the above.

[0002]

2. Description of the Related Art Conventionally, bathing methods using shobu-to or yuzu-to have been widely used in households. Recently, health-conscious or medicinal effects, relaxing effects for relieving stress, and relief of skin irritation by Sara-to have been used. Various bathing agents for the purpose are commercially available. These conventionally known ordinary bath preparations are generally produced by blending a crude drug extract, an oil component, a flavoring agent, a coloring agent, etc. with inorganic salts collected from a hot spring component and then subjecting them to a drying process. , Powdery, granular or liquid. Granular bath preparations are mainly foamed products that generate carbon dioxide gas in hot water. In addition, the powdered bathing agent is used by enclosing a herb or a component extracted from the hot spring in a porous bag with a fragrance and a coloring agent, and immersing the bag in a bathtub and rubbing it out. There is a type to do.

[0003]

However, these conventional bath preparations have no inhibitory action on inflammation that occurs in the human body and contain a water-insoluble substance as a humectant, so that they have a sticky feeling. There is a drawback that exhilaration is lacking. Inflammation in particular occurs as a biological reaction when foreign substances come into contact with or invade the living body, such as when being stuck by a bee or an ant. Cannot suppress inflammation. Further, conventional bath preparations do not naturally have a healing effect on skin disorders such as atopic dermatitis.

[0004] Therefore, the present invention is different from such conventional bath preparations in that the main component is a mineral component of seawater, thereby eliminating the sticky feeling at the time of bathing and enhancing the refreshing feeling.
The purpose of the present invention is to provide a bath preparation which exerts an inhibitory effect of inflammation caused by a calcium silicate salt contained in a lyophilized salt and has a healing effect on skin disorders such as atopic dermatitis. is there.

[0005]

In order to achieve the above object, the present invention provides a bath preparation comprising a seawater-based lyophilized salt and a liquid comprising a seawater-based lyophilized salt. Thus, the basic means is a bathing agent which has a human body inflammation suppressing effect by the calcium silicate salt contained in the freeze-dried salt. As the liquid, any one or a plurality of liquids of raw water of deep ocean water, concentrated seawater of deep ocean water, tap water or mineral spring water is used.

[0006] The mixing ratio of the lyophilized salt to the liquid is 0.04% to 20%. Further, a coloring agent is added to a bath preparation obtained by blending a lyophilized salt using seawater as a raw material in a liquid. 0.001% to 10%
And Then, as the freeze-dried salt to be blended, a freeze-dried salt using deep sea water as a raw material is used.

[0007] A specific production means is to put one or more liquids of raw water of deep ocean water, concentrated seawater, tap water or mineral spring water into a stirring and mixing tank, and further freeze-dried salt. After the freeze-dried salt is put into the storage tank and mixed with stirring, it is separated into salt water and a bath additive, and a coloring agent is added to the obtained bath agent from the colorant storage tank to complete the bath.

According to such a bath additive, there is no water-insoluble substance as a moisturizing agent contained in the conventional bath additive, and since it is mainly composed of a mineral component of seawater, the feeling of freshness at the time of bathing is eliminated and the refreshing feeling is enhanced. In addition, a bath preparation is provided which exhibits an inflammation-suppressing action of calcium silicate contained in the lyophilized salt and has a healing effect on skin disorders such as atopic dermatitis.

[0009]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Specific embodiments of a bath agent according to the present invention will be described below with reference to the drawings. A major feature of the present invention is that a freeze-dried salt made from seawater is blended in a liquid, and accordingly, the inflammation-suppressing action of calcium silicate contained in the freeze-dried salt is effectively utilized. can do.

The inventor of the present invention has found that calcium silicate has an inflammation-suppressing effect and is effective when added to a bath preparation, and that the calcium silicate is not contained in naturally dried salts and is freeze-dried. It was found that it was contained only in salt. Furthermore, it was confirmed that the calcium silicate salt was contained about 4.7 times more in the freeze-dried salt using the deep sea water as the raw material than the freeze-dried salt using the normal surface ocean water as the raw material. .

As the liquid containing the freeze-dried salt, raw water of deep sea water or concentrated sea water of deep sea water is suitable, but ordinary tap water or mineral spring water may be used. It is also effective to add a coloring agent to enhance the commercial value as a bathing agent. Further, when commercializing as a bath additive, water may be removed to form a powder.

FIG. 1 is a block diagram showing a production process of concentrated seawater suitable for blending freeze-dried salt, wherein 1 is a storage tank for deep sea water, 2 is a simple filtration device, 3 is a high-pressure pump, 4 is It is a reverse osmosis membrane module. Then, a predetermined amount, for example, 15 tons of deep sea water is stored in the storage tank 1, and the deep sea water is filtered by the simple filtration device 2 and then sent to the reverse osmosis membrane module 4 using the high-pressure pump 3, where Demineralized water 5 and concentrated seawater 6 are obtained. Demineralized water 5
Is used for soft drinks and the like, and the concentrated seawater 6 is used for the bath agent of the present invention.

FIG. 2 is a block diagram showing a process for producing a lyophilized salt to be mixed with the concentrated seawater 6 obtained as described above.
7 is a storage tank for deep sea water, and 8 is a programmable freeze dryer. Then, a predetermined amount, for example, 24 liters of deep sea water is sent from the storage tank 7 to the single-chamber programmable freeze dryer 8, the trap cooling temperature is -56 ° C, the dehumidification amount is Max 24 kg (water), and the pre-freezing tank temperature is-. By freeze-drying at 48 ° C., a freeze-dried salt 9 is obtained. 800g lyophilized salt per day
Can produce 200 bottles per liter.

FIG. 3 is a block diagram showing a manufacturing process of the bath salt according to the present embodiment, wherein 10 is a lyophilized salt storage tank, 11 is a concentrated seawater storage tank, 12 is a stirring and mixing tank, and 13 is a colorant storage tank. is there. At the time of manufacturing the bath salt, the cock 10a of the freeze-dried salt storage tank 10 and the cock 11a of the concentrated seawater storage tank 11 are opened and closed,
The 0.2% -0.8% lyophilized salt 9 and 200 liters of concentrated seawater 6 are put into the stirring and mixing tank 12 and sufficiently stirred and mixed, and the food-added salt water 14 is opened and closed by opening and closing the cocks 12a and 12b. And bath agent 15. The food-added salt water 14 is sterilized in step 16 and then bottled into a product, and the bath agent 15 is stored in the colorant storage tank 13 from the colorant storage tank 13 by opening and closing the cock 13a as necessary.
cc blue No. 205 colorant is added to complete the bath, sterilized in step 17 and bottled to produce a product.

Instead of the concentrated seawater 6, a liquid such as raw deep sea water, ordinary tap water or mineral spring water can be used. The mixing ratio of freeze-dried salt to these liquids is 0.1%.
04% to 20% is suitable. Further, the mixing ratio of the colorant is preferably set to 0.001% to 10%, and the optimum amount is 0.01% to 10%.
1% to 1%. Examples of the form of the bathing agent include a bottled liquid bathing agent, a bathing agent-containing spray, and a powdered bathing agent with a measuring cup.

The following experiment confirmed that the above-mentioned calcium silicate salt was not contained in naturally dried salt, but was contained only in freeze-dried salt. FIG. 4 is a spectrum diagram showing a pattern of a registered substance of naturally dried salt obtained from deep sea water by X-ray diffraction, and FIG. 5 is a search result collation diagram. FIG. 5 shows no calcium silicate salt.

On the other hand, FIG. 6 is a spectrum diagram showing a pattern of a registered substance of a lyophilized salt using deep ocean water as a raw material by X-ray diffraction, and FIG. 7 is a search result collation diagram. From FIG. 7, the calcium silicate salt Ca ₃ (SiO ₄ ) O can be confirmed as a silicate tetrahedral three-dimensional structure.

As described above, calcium silicate salt having an inflammation-suppressing action is not contained in naturally dried salts, but is contained only in freeze-dried salts. When a fresh blood cell freshness test was performed,
This mixture was found to produce a strong reducing atmosphere, prevent fish from oxidizing, and maintain freshness. It was also found that when the lyophilized salt 9 added to the bath agent was dissolved in a solvent to form an aqueous solution, the pH value increased. This is presumed to be due to the calcium silicate salt contained in the freeze-dried salt 9.

Table 1 shows the results of a hemolysis test of erythrocytes of fish with a mixed solution of alkaline water and seawater. After 3 days, the mixing ratio of alkaline water and seawater was sequentially changed from 10: 0 to 0:10. After 14 days, the hemolytic state after 14 days and the mutation in the nucleus of red blood cells after 13 days were measured.

[0020]

[Table 1]

According to Table 1, when the alkalinity is strong, red blood cell membrane destruction occurs and hemoglobin is eluted. The cell membrane is composed of fat, and it is presumed that alkaline water causes fatty degeneration. Seawater causes nuclear degeneration, but the nucleus is a basic salt. It is presumed that the alkaline water corresponds to a lyophilized salt, and that the action as a bathing agent varies depending on the blending ratio with seawater. The blending ratio of the lyophilized salt to concentrated seawater is 0.4% at an appropriate ratio. Yes, it can suppress the activity of inflammatory substances.

Freeze-dried salt 9 obtained from deep ocean water
The assumed chemical formula of is shown in FIG. Ca ₃ (SiO ₄ ) O + 3H ₂ O → (CaOH) ₃ (SiO ₄ ) OH + 2H (1) When a calcium silicate salt contained in a lyophilized salt is converted to an aqueous solution, it shows a high pH value and has a reducing property. Reason,
(1) It is thought to be due to two hydrogen atoms in the formula.

On the other hand, inflammation occurs as a biological reaction when a foreign substance outside the living body comes into contact with or invades the living body. When inflammation occurs when a bee or ant is stuck, a primary site is generated by a poison that causes inflammation, red histamine secretion is caused by mast cells around it, and eicosanoid, a late-onset inflammatory substance, is also surrounded by it. appear. Usually, → is immediate flame and is within 1 hour, → is late flame and is about 8 hours.

On the other hand, it has been reported that electrolytically reduced water has an effect on the signal transduction pathway that suppresses cancer cell growth, and this indicates that the reducing action of the bath agent 15 affects the inside of the cell. Can be considered. Silicate forms a complex with alum sulfate to provide a strong catalytic action, and the anti-inflammatory action is an oxidation-reduction reaction. The calcium silicate salt in the freeze-dried salt is also an aqua complex salt [Mg (H
₂ O) ₆ ] SO ₄ .H ₂ O to form a complex and participate in the oxidation-reduction reaction. Since phospholipase A ₂ and more initiator of inflammation are oxidized bond (-S-S-), which calming inflammation phospholipase A ₂ and inactivated as -HS-SH- by reducing action it is conceivable that.

The above phospholipase A₂Is lecithinase
A, also known as phosphatidase and phosphatidlipase
Glycerophospholipid sn-2 which is a main component of biological membrane
Hydrolyze the ester bond at the lysophospholipid and fatty acid
PLA is a generic term for a group of enzymes that release ₂Abbreviated as prokaryotic cell
To mammals. High motion to date
PLA isolated from a product₂Are all soluble and
Secretory phospholipase A having a molecular weight of 14,000
₂(SPLA₂) And 85,000 molecular weight cytoplasmic phospho
Lipase A₂(CPLA₂)are categorized. PLA₂Is
Arachidonic acid, in addition to its important role in membrane lipid rearrangement
Platelet activity derived from eicosanoids and lysophospholipids
Activity in response to stimuli, such as activating factors and lysophosphatidic acid
In recent years, it has attracted attention as a rate-limiting enzyme for lipid production.

As a clinical test, the bath agent 15 according to the present invention was immersed in absorbent cotton and applied to the affected area for 30 minutes at the time when the eicosanoid, which is a late-onset inflammatory substance, occurred. The swelling has disappeared. This proved that Bath Agent 15 was effective for late-onset inflammation.

Late-onset inflammatory substances include eicosanoids (leukotoluenes and prostaglandins), which are said to cause late-onset allergies. The snake, bee venom has been included in the large amount of phospholipase A _2, to induce a delayed-inflammatory substances. Secreted phospholipase A ₂ (s
PLA ₂ ) is correlated with inflammation, and when injected into a living body, inflammation occurs. The phospholipase A ₂ to the primary site by poisoning described is injected is estimated that inflammation has progressed.

[0028] Phospholipase _{A 2} has got -S-S- (disulfide bond), phospholipase _{A 2} is inactivated by the site by reducing action of bath agent 15 of the present invention and -HS-SH- . This reducing action involves a complex of calcium silicate and alum sulfate. Therefore, the reducing action of the bath agent 15 can promote the calming and disappearance of inflammation.

Here, the deep sea water used in the present invention will be described. As described above, it has been found that the freeze-dried salt made from deep ocean water contains about 4.7 times as much calcium silicate salt as the freeze-dried salt made from ordinary surface ocean water. did. In recent years, the cleanliness and abundant mineral components of deep ocean water have attracted the attention of consumers and have caused a boom, and the water obtained by desalinating the deep ocean water has entered the field of drinking water. Deep ocean water is currently being used practically only at three locations around the world: off the coast of Norway, off the coast of Hawaii, and off the coast of Cape Muroto in Kochi Prefecture. Seawater in an environment where there is no accompanying convection and mixing, and is not affected by marine pollution caused by harmful substances such as various oils, chemicals, and pesticides used on the ground. It has the characteristic of very little dissolved organic matter and is extremely clean from a microbial point of view. Water temperature is as low as 13 ° C. or less on average every year, and contains many natural elements required by the human body.

Table 2 is a table showing the results of analysis on various items of the ocean surface water and the deep sea water. Looking at the general items, the average water temperature is 21 ° C. for the ocean surface water and 13 cm for the deep ocean water. PH was as low as 8.87 ° C for 7.19 and DO was 7.28 for 8.33 mg / L.
mg / L, TOC is 0.98 for 1.60 mg / L.
mg / L, both of which are lower in deep sea water, but the viable cell count is 10 ³ to 10 ⁴ for deep sea water,
² , the number of viable bacteria in deep ocean water is one order of magnitude or less compared to that in surface water, and it contains almost no pathogenic organisms. There is no fear at all.

[0031]

[Table 2]

In the item of nutrients as mineral components, NO ₃ -N contained 1.49 μg-at / L in ocean surface water, 25.9 μg-at / L in deep ocean water, and PO ₄ -N.
P is 1.65 μg-a against 0.34 μg-at / L.
t / L and SiO ₂ -Si are 13.6 μg-at / L and 64.2 μg-at / L, which is much larger in deep ocean water. Analysis results have also been obtained that the content of deep ocean water is higher than that of ocean surface water for other trace element items.

The desalinated water of deep sea water was analyzed by atomic absorption spectroscopy. As a result, calcium was 0.4 mg / L,
It was found that magnesium was contained at 1.0 mg / L. Furthermore, the concentrated water of the deep ocean water was similarly analyzed by atomic absorption spectrometry, and as a result, it was found that calcium contained 560 mg / L and magnesium contained 1700 mg / L.

Table 3 shows the results of measuring data comparing the pH, the electric conductivity, and the contained elemental components for the raw water, the concentrated water, and the desalinated water, respectively, of the deep ocean water.

[0035]

[Table 3]

The deep ocean water employed in the present invention is seawater taken from a depth of 374 meters off Cape Muroto, and among the three forms of nitrogen contained in the deep water, ammonia nitrogen and nitrite nitrogen are extremely small. The effect on living organisms was slight, and the amount of nitrate nitrogen was very small in the surface layer. However, as the water depth increased, the concentration increased,
More than 95% of inorganic dissolved nitrogen in water at a depth of 0 meters or less is nitrate nitrogen at 24 μM. In addition, 1.7 μM of phosphoric acid phosphorus and 41 μM of silicate silicon are dissolved, and each has a nutrient concentration of 5 to 10 times or more that of the surface layer.

In the present invention, a freeze-dried salt made from the above-mentioned deep sea water is blended into one or more of the raw water of the deep sea water, the concentrated sea water, the tap water and the mineral water of the deep sea water. It is a major feature of the present invention to obtain a bath agent mainly composed of mineral components of seawater and having an inflammation inhibitory effect on the human body by a calcium silicate salt.

[0038]

As described above in detail, according to the present invention, the bath preparation does not contain a water-insoluble substance as a humectant, and is mainly composed of mineral components of seawater. Provides a bath preparation that enhances exhilaration by eliminating the feeling of sensation, and has the effect of inhibiting inflammation caused by calcium silicate contained in freeze-dried salt and also has the effect of curing skin disorders such as atopic dermatitis. can do.

In particular, inflammation of the human body occurs as a biological reaction when a foreign body comes into contact with or invades a living body, such as when being stuck by a bee or an ant. On the other hand, a calcium silicate salt, which is contained in a large amount in a freeze-dried salt using deep seawater as a raw material, can effectively act to exert an inflammation suppressing effect on the human body.

[Brief description of the drawings]

FIG. 1 is a block diagram showing a production process of concentrated seawater used in the present invention.

FIG. 2 is a block diagram showing a process for producing a freeze-dried salt to be mixed with concentrated seawater.

FIG. 3 is a block diagram showing a manufacturing process of the bath agent according to the present embodiment.

FIG. 4 is a spectrum diagram showing a pattern of a registered substance of naturally dried salt in deep sea water by X-ray diffraction.

FIG. 5 is a search result collation diagram of the registered substances of FIG. 4;

FIG. 6 is a spectrum diagram showing a pattern of a registered substance of lyophilized salt of deep sea water by X-ray diffraction.

FIG. 7 is a search result collation diagram of the registered substances in FIG. 6;

FIG. 8 is an assumed chemical formula of a lyophilized salt.

[Explanation of symbols]

 1,7 ... Deep sea water storage tank 2 ... Simple filtration device 3 ... High pressure pump 4 ... Reverse osmosis membrane module 5 ... Demineralized water 6 ... Concentrated seawater 8 ... Programmable freeze dryer 9 ... Freeze dried salt 10 ... Freeze dried salt storage Tank 11: concentrated seawater storage tank 12: stirring and mixing tank 13: colorant storage tank 14: food additive salt water 15: bath additive Reference number P3193

Claims (8)

[Claims] 1. A bath preparation comprising a freeze-dried salt made from seawater. 2. A lyophilized salt containing seawater as a raw material is incorporated into a liquid, so that calcium silicate contained in the lyophilized salt has an effect of suppressing inflammation of the human body. Bath salts to do. 3. The liquid according to claim 1, wherein the liquid is one of raw water of deep sea water, concentrated seawater of deep sea water, tap water and mineral spring water.
3. The bath preparation according to claim 2, wherein a seed or a plurality of liquids is used. 4. The bath preparation according to claim 2, wherein the mixing ratio of the lyophilized salt to the liquid is 0.04% to 20%. 5. A coloring agent is added to a bath preparation obtained by blending a freeze-dried salt made from seawater into a liquid.
The bath agent according to 3 or 4. 6. The mixing ratio of the colorant is 0.001% to 10%.
% Of the bath agent according to claim 5. 7. The bath preparation according to claim 1, wherein the freeze-dried salt is a freeze-dried salt obtained from deep ocean water. 8. The raw water of deep ocean water in the mixing tank.
Inject one or more liquids of concentrated seawater, tap water or mineral spring water from deep ocean water, further add lyophilized salt from a lyophilized salt storage tank and mix by stirring. A bath agent obtained by adding a colorant from a colorant storage tank to the obtained bath agent to obtain a bath agent.