JP2002060334A - After-sunburn sheet - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an after-sunburn sheet having excellent suppressing effect on inflammation of the sun-burnt skin and decreasing the pigmentation. SOLUTION: This after-sunburn sheet is composed of a transparent or translucent water-containing gel. A woven, knit or nonwoven cloth having a sufficiently large open area ratio is included in the sheet in the direction of thickness.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a sheet-like preparation having an excellent effect of suppressing hot flashes after sunburn. More specifically, the present invention relates to a sheet for aftersun, which is excellent in the effect of calming skin inflammation after sunburn and relieving pigmentation by using a sheet-like preparation excellent in cooling effect and replenishing ability of moisture and humectant.

[0002]

2. Description of the Related Art Sunburn is a kind of burn. As a countermeasure, the affected part is cooled with water or ice, or an anti-inflammatory agent is applied. Tanned skin loses its barrier ability, so it loses not only its defense against bacteria and immunity against various components, but also its ability to retain water, and water is rapidly lost from the skin. State. Furthermore, when applying cosmetics containing oils to tanned skin, the components may be absorbed percutaneously, and even components that do not cause problems without being absorbed percutaneously in normal skin may cause problems in tanned skin. The possibility of occurrence cannot be denied. For this reason, it is a fact that the practice is not to use cosmetics for sunburned skin.

[0003]

SUMMARY OF THE INVENTION There is a need for a preparation which is excellent in the effects of supplementing moisturizing ingredients, suppressing moisture transpiration and protecting the skin from bacteria while safely cooling tanned skin. I was

[0004]

Means for Solving the Problems The present inventors provide a sheet-like preparation comprising a hydrogel having a transparent or translucent appearance, and a woven or nonwoven fabric having a sufficiently large opening ratio inside the sheet. Focusing on the fact that the sheet-form preparation, which is characterized in that it is embedded in the thickness direction, is excellent in cooling effect and has a transparent appearance, so that the skin condition can be easily understood, and studies for improving the symptoms of sunburn are considered. Done. As a result, they found that the sheet suppressed moisture evaporation of the skin to maintain skin moisture and suppressed inflammation by a strong cooling effect. Furthermore, by using a dosage form in which a moisture layer is formed on the surface of the sheet during use, the sheet is fixed to the skin by adhesion due to the surface tension of water, instead of using an adhesive as in existing sheet-like preparations As a result, it has been found that the burden on the damaged skin can be reduced, and the present invention has been completed.

That is, a first aspect of the present invention is a sheet preparation comprising a hydrogel having a transparent or translucent appearance,
A sheet for after sun, characterized in that a woven or nonwoven fabric having a sufficiently large aperture ratio is provided inside the sheet in the thickness direction.

According to a second aspect of the present invention, there is provided the after-sun sheet, wherein the sheet contains a moisturizing component.

According to a third aspect of the present invention, there is provided the after-sun sheet, wherein the sheet contains an anti-inflammatory component and / or an antibacterial component.

[0008] A fourth aspect of the present invention is the above after-sun sheet, characterized in that the sheet contains a whitening component and / or a radical scavenger component.

According to a fifth aspect of the present invention, there is provided the after-sun sheet, wherein the surface of the sheet is covered with a liquid component containing water.

According to a sixth aspect of the present invention, there is provided the after-sun sheet, wherein the surface of the sheet is covered with a liquid component containing water at the time of use.

[0011]

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the present invention will be described in detail. The after-sun sheet of the present invention is a sheet preparation comprising a transparent or translucent hydrated gel body in appearance,
A woven or nonwoven fabric having a sufficiently large aperture ratio is provided inside the sheet in the thickness direction.
By being transparent or translucent, there is a characteristic that a feeling of strangeness at the time of use is eliminated and a change in skin condition can be observed through the sheet.

The term "transparent or translucent" as used herein means that when the sheet for aftersun is pasted on a white paper on which a black line (2 mm in width) is drawn, the black line can be clearly recognized by the naked eye. Judgment is made based on the criteria that vaguely recognizable objects are translucent and unrecognizable objects are opaque. A knitted woven fabric or nonwoven fabric having a sufficiently large aperture ratio as described above means that the woven fabric or nonwoven fabric can be passed through the woven fabric or nonwoven fabric.
It has a wide aperture ratio (transparency is maintained) so that the black print of the point can be read with the naked eye. For example, a mesh made of nylon or polyester is preferably used.

[0013] The after-sun sheet of the present invention preferably contains a moisturizing component. The moisturizing component has a high effect of suppressing abnormal moisture evaporation of the skin. Examples of the moisturizing component in the present invention include polyhydric alcohols, sugars, sugar alcohols, sugar derivatives, and plant extracts. For example,
Ethylene glycol, propylene glycol, butylene glycol, diethylene glycol, triethylene glycol, dipropylene glycol, glycerin, diglycerin, sorbitol, malbitol, trehalose,
Raffinose, xylitol, mannitol, cyclodextrin, polyethylene glycol, polyglycerin, glycols such as hyaluronic acid and salts thereof, polyhydric alcohols and polysaccharides; trehalose ester,
Various sugar derivatives such as a raffinose ester and a raffinose ether are exemplified. These can be used alone or 2
It is preferable to use a mixture of two or more species. The amount of the moisturizing component is preferably 0.01 to 80% by mass, more preferably 0 to 80% by mass in terms of the solid content of the moisturizing component with respect to the mass of the hydrogel portion of the sheet excluding the internal support, protective sheet and the like. 0.1 to 60% by mass.

The after-sun sheet of the present invention preferably contains an anti-inflammatory component and / or an antibacterial component. The anti-inflammatory component is effective in suppressing skin inflammation synergistically with the cooling effect of the sheet, and the antimicrobial component is effective in protecting the skin, which has weakened defense and is easily infected, from bacteria. Examples of these components include anti-inflammatory agents and antibacterial components such as synthetic medicinal components and plant-based crude drugs. For example, tea extract, hinokitiol, apple extract, wasabi extract, mugwort extract, sasa extract, sagebrush extract, ε-aminocaproic acid, glycyrrhizic acid, β-
Glycyrrhetinic acid, lysozyme chloride, ethanol, guaiazulene, hydrocortisone, benzoic acid, sodium benzoate, undecylenic acid, salicylic acid, sorbic acid,
Potassium sorbate, dehydroacetic acid, sodium dehydroacetate, paraoxybenzoate, paraoxybenzoate, isopropylmethylphenol, chlorhexidine gluconate, cresol, chlorothymol, chlorophenesin, chloroxylenol, chlorocresol, dichloroxylenol, dichloro Benzyl alcohol, thiobischlorophenol, thymol, triclocarban, triclosan, sodium phenoxide, parachlorophenol, halocarban, phenylethyl alcohol, phenylphenol, sodium phenylphenol, phenoxyethanol, phenol,
Hexachlorophen, benzyl alcohol, stearyl dimethyl benzyl ammonium chloride, stearyl trimethyl ammonium chloride, cetyl trimethyl ammonium chloride, cetyl pyridinium chloride, benzalkonium chloride, benzethonium chloride, methyl benzethonium chloride,
Lauryl trimethyl ammonium chloride, lauryl pyridinium chloride, lauroyl colaminoformyl methyl pyridinium chloride, alkyl isoquinolinium bromide solution, cetyl trimethyl ammonium bromide, domiphen bromide, lauryl trimethyl ammonium bromide, cetyl trimethyl ammonium saccharin, alkyl diamino hydrochloride Ethyl glycine solution, Platonin, Pionin, Luminex, Photosensitizer N
K143, glutaral, chloramine T, chlorhexidine, dibromopropamidine diisethionate, zinc pyrithione, sodium pyrithione, 5-bromo-5-nitro-1,3-dioxane, furfural and the like. It is preferable that the compounding amount is in accordance with the effect manifestation concentration of each component, but the compounding amount (extracts, extracts, etc., in terms of dry residue) is 0.001 to 0.001 to the sheet preparation composed of a hydrogel. 10% by mass is preferred. For example, if the mugwort extract is 0.3 wt.
About mass% is preferable.

The sheet of the present invention preferably contains a whitening component and / or a radical scavenger component. A whitening component and a radical scavenger have an effect of suppressing the deposition of a pigment due to ultraviolet rays. As these components, various plant extract components, synthetic components, and microbial components are preferable.
As a component having a whitening effect, for example, arbutin,
Ellagic acid, Kojic acid, Placenta extract, Ascorbic acid, Sodium ascorbate, Magnesium ascorbate phosphate, Ascorbic acid fatty acid ester, Ascorbic acid glucoside, Other ascorbic acid derivatives, Lucinol, Glutathione, Linoleic acid, Linolenic acid, Lactic acid, Lactic acid, Tranexamic acid, biphenyl compounds,
Pantethein-calcium S-sulfonate, sulfur, oil-soluble licorice extract (grabridine), raspberry ketone glucoside, awaurushi extract, licorice extract, almond extract, aloe extract, ginkgo extract, ibukitorano extract, age extract extract, ogre extract, spinach extract, hypericum Extracts, lycopodium extract, seaweed extract, chamomile extract, cuckoo (waste) extract, yellowfin extract, gardenia extract, clara (kujin) extract, cranberry extract, chlorella extract, brown sugar extract, mulberry (sour bud) extract, gentianiana extract, black tea Extract, gobyshi extract, wheat extract, rice germ oil, rice bran extract, saishin extract, sansho extract, perilla extract, peony extract, honeysuckle extract, sage extract Sen Ryukyu extract, soybean extract, green tea extract, Japanese angelica root extract, Toukinsenkaekisu, Tounin'ekisu, Houttuynia cordata extract, garlic extract, witch hazel extract, Biwaekisu, safflower extract,
Button extract, matsuhod extract, marronnier extract, melissa extract, yokuinin (adlay) extract, saxifrage extract, waremokou (ju) extract, mugwort extract,
Fire thorn extract, hibiscus extract and the like. Among them, in particular, placenta extract, ascorbic acid, sodium ascorbate, magnesium ascorbate phosphate, fatty acid ester of ascorbate, ascorbic acid glucoside, oil-soluble licorice extract, and plant extract are preferable because of their versatility and stability. Examples of the radical scavenger component include tocopherols (vitamin E), nordihydroguaiaretinic acid, butylhydroxyanisole, dibutylhydroxytoluene, propyl gallate, sodium bisulfite, erythorbic acid, sodium erysorbate, and thiodipropione. Dilauryl acid, torilbiguanide, p-hydroxyanisole,
Octyl gallate, anhydrous sodium sulfite, tea extract,
Ascorbyl palmitate, ascorbyl stearate, apple extract, dehydrodicresol, apple polyphenol, lycopene, rosemary extract, mothra extract, hibiscus extract, cranberry extract, seaweed extract, ascorbic acid, clove extract, melissa extract, spinach extract, Licorice extract, oil-soluble licorice extract, hamamelis extract, fennel extract, loquat extract, fire spike, superoxide dismutase, malonie extract, deoxyribonucleic acid and its salts, carotenoid, flavonoid, tannin, lignan, saponin, phytic acid, and the like. The blending amount of the whitening component and / or the radical scavenger component (extracts and extracts, other than pure products, in terms of dry residue) is 0.001 to 10% by mass based on the sheet preparation comprising the hydrogel. preferable.

In the after-sun sheet of the present invention, a method is employed in which the surface of the sheet is previously covered with a liquid component containing water, or the surface of the sheet is covered with a liquid component containing water at the time of use. Is preferred. Since the surface of the sheet is covered with the liquid component containing water at the time of use, there is an advantage that physical stimulation of the gel on the damaged skin is suppressed and a cooling effect by the liquid water is effectively obtained.

In the after-sun sheet of the present invention, it is preferable that a component which promotes cell growth is blended together with the above-mentioned components. Examples of components that promote cell proliferation include:
Known components include, for example, soluble eggshell membranes, oolong tea extract, deoxyribonucleic acid, collagen, elastin, allantoin, bovine spleen extract, calf thymus extract,
Examples include milk protein digest, bovine blood digest, yeast extract, lactic acid bacterium extract, fermented milk extract, and reishi extract, and the soluble eggshell membrane is particularly preferred because of its high effect.

The details of the production example of the aftersun sheet of the present invention are shown below. The sheet for after sun of the present invention,
It is preferably composed of a synthetic polymer having at least a network structure and a solvent containing water, or is preferably a gel composed of a tackifier, preferably colorless, or colored transparent or translucent, and It is characterized by having shape retention. The structure of the after-sun sheet may be a single layer or may have two or more layers.
When using a thickener, carrageenan, gellan gum,
Conventionally known thickeners such as xanthan gum, macrohomosis gum, agar, and gelatin can be used. The amount of the synthetic polymer having a network structure and the amount of the adhesive is determined with respect to the cosmetic portion (hereinafter referred to as a gel body) in the acne treatment sheet.
It is preferably from 1 to 50% by mass.

The proportion of water in the gel body is 1 to 99% by mass.
It is preferred that If the proportion of water in the gel body is less than 1% by mass, there is a possibility that various additives such as medicinal ingredients and the like to be blended in the gel body cannot be easily dissolved. Conversely, if the proportion of water in the gel body exceeds 99% by mass, the stiffness of the gel body becomes weak, and it is difficult to stably maintain additives such as solvents and medicinal ingredients contained in the gel body. Could be. The proportion of water in the gel body is particularly preferably 5 to 95% by mass, more preferably 10 to 85% by mass in the above range.

The solvent constituting the above gel body is not water and does not cause phase separation with water. Conventionally, it has been used for transdermal applications in the fields of cosmetics, pharmaceuticals, quasi-drugs, sanitary materials, sundries and the like. Any solvent may be used as long as it is used. Examples of such a solvent include monoalcohols such as ethyl alcohol, glycols such as 1,3-butylene glycol, and polyhydric alcohols such as glycerin.
These can be used alone or in combination of two or more.

The proportion of the solvent other than water in the gel body is 98
It is preferable that the content is not more than mass%. When the proportion exceeds 98% by mass, there is a possibility that various additives and the like blended in the gel body cannot be easily dissolved. Furthermore, the stiffness of the gel body may be weakened, and it may be difficult to stably maintain additives such as a solvent and a medicinal component contained in the gel body.

The synthetic polymer having a network structure constituting the gel body has an affinity for water and has at least 6
The gel structure is retained even after storage at 0 ° C for one month, and it is particularly limited except that it is conventionally used as a transdermal application in the fields of cosmetics, pharmaceuticals, quasi-drugs, sanitary materials, sundries, etc. Instead, various synthetic polymers can be used.

Among them, from the viewpoint of easy manufacture,
(A) a copolymer of one or more polymerizable unsaturated monomers and a crosslinkable unsaturated monomer, or (b) a carboxyl group, a sulfonic acid group, a hydroxyl group, an amide group, A hydrophilic synthetic polymer obtained by polymerizing one or more polymerizable unsaturated monomers having at least one functional group selected from the group consisting of amino groups, and a polyvalent metal ion compound; A crosslinked structure obtained by reacting with at least one crosslinking factor selected from the group consisting of polycarboxylic acids, polyhydric alcohols, polyfunctional epoxides and dialdehydes is preferably used.

Examples of the hydrophilic synthetic polymer having a carboxyl group in the side chain include poly (meth) acrylic acid and those obtained by neutralizing a part or all of the carboxyl group with an alkali such as sodium hydroxide. Examples of the hydrophilic synthetic polymer having a sulfonic acid group in the side chain include poly-t-butylacrylamide sulfonic acid and those obtained by neutralizing a part or all of the sulfonic acid group with an alkali such as sodium hydroxide. Examples of the hydrophilic synthetic polymer having a hydroxyl group in a side chain include polyvinyl alcohol obtained by polymerizing and hydrolyzing a vinyl acetate monomer. Examples of hydrophilic synthetic polymers having an amide group in a side chain include poly (meth) acrylamide, polyN, N′-dimethyl (meth) acrylamide, polyvinylpyrrolidone, and polyN-
Vinylacetamide and the like. Examples of the hydrophilic synthetic polymer having an amino group in the side chain include polyallylamine, one in which some or all of the amino groups are neutralized with an acid such as hydrochloric acid, and polymethacryloyltrimethyloxyethylammonium chloride.

The monomer constituting the above-mentioned hydrophilic synthetic polymer may have, in addition to a carboxyl group, a sulfonic acid group, a hydroxyl group, an amide group and an amino group, a functional group obtained by modifying these groups. For example, a treatment for esterifying about 40% of the hydroxyl groups or carboxyl groups in the hydrophilic synthetic polymer to make it lipophilic may be performed for the purpose of improving the adhesion to the skin. Further, when there is a long saturated hydrocarbon portion in the side chain, for the purpose of imparting hydrophilicity to the portion,
Further, a carboxyl group, a sulfonic acid group, a hydroxyl group, an amide group, an amino group or the like may be introduced, or treatment with a reagent such as an acid or an alkali may be performed. These treatments may be performed before the polymerization of the monomer or after the polymerization.

Examples of the polymerizable unsaturated monomer include (meth) acrylic acid (and its salt); t-butylacrylamide sulfonic acid (and its salt), N, N'-dimethylacrylamide, dimethylaminopropyl methacrylamide and the like. (Meth) acrylamide derivative; vinylpyrrolidone and the like are preferably used from the viewpoint of easy production. The polymerizable unsaturated monomer may be used alone or
A mixture of more than one species is used.

As the crosslinkable unsaturated monomer, for example, N,
N'-methylenebisacrylamide, N, N'-methylenebismethacrylamide, N, N'-ethylenebisacrylamide, N, N'-ethylenebismethacrylamide, 1,2-diacrylamideethylene glycol and the like.

As described above, the crosslinking factor may be a polyvalent metal ion compound, a polyvalent carboxylic acid, a polyhydric alcohol,
Examples include polyfunctional epoxides and dialdehydes. Among them, examples of the polyvalent metal ion compound include an aluminum compound, a calcium compound, and a magnesium compound. Among them, from the viewpoint of crosslinking efficiency, aluminum hydroxide and a salt thereof, synthetic aluminum silicate, magnesium aluminate metasilicate, magnesium aluminum oxide, aluminum oxide, dihydroxyaluminum amino acetate, magnesium aluminum hydroxide carbonate hydrate,
Compounds containing trivalent aluminum ions such as aluminum hydroxide sodium carbonate coprecipitate are preferred, and those having an amorphous structure are more preferred. Examples of the polycarboxylic acid include succinic acid, fumaric acid, phthalic acid, citric acid, malic acid and the like. Examples of the polyhydric alcohol include ethylene glycol, propylene glycol, butanediol, glycerin, diethylene glycol, diglycerin and the like. As the polyfunctional epoxide, for example, ethylene glycol diglycidyl ether, polyethylene glycol diglycidyl ether, propylene glycol diglycidyl ether, polypropylene glycol diglycidyl ether, polytetramethylene glycol diglycidyl ether, glycerol polyglycidyl ether, polyglycerol polyglycidyl ether, Sorbitol polyglycidyl ether, sorbitan polyglycidyl ether, trimethylolpropane polyglycidyl ether, pentaerythritol polyglycidyl ether, resorcin diglycidyl ether, neopentyl glycol diglycidyl ether,
1,6-hexanediol diglycidyl ether and the like. Examples of dialdehydes include glyoxal, terephthalaldehyde, glutaraldehyde and the like.

In the single synthetic polymer gel for forming the after-sun sheet of the present invention, the amount of the synthetic polymer having a network structure constituting the gel is 1 to 50% by mass relative to the gel. %. If the compounding amount of the synthetic polymer is less than 1% by mass, the stiffness of the gel body is weakened, and it may be difficult to stably maintain additives such as a solvent and a medicinal component contained in the gel body. . Conversely, if it exceeds 50% by mass, the gel strength is increased, but the polymer structure of the gel body becomes too dense, and the amount of the solvent, medicinal component and the like that can be retained in the gel body may be too small. . The compounding amount of the synthetic polymer is particularly preferably 3 to 30% by mass, more preferably 5 to 25% by mass in the above range.

When the copolymer (a) is used as the synthetic polymer having a network structure, the amount of the crosslinkable unsaturated monomer is 0.005 to 0.5% by mass based on the gel. Preferably it is. If the amount is less than 0.005% by mass, it is difficult to obtain a gel having sufficient waist strength, and it may be difficult to stably maintain additives such as a solvent and a medicinal component contained in the gel. is there. Conversely, if the compounding amount exceeds 0.5% by mass, the brittleness of the obtained gel body increases, and there is a possibility that cutting or breaking may easily occur due to tensile stress or compressive stress.

On the other hand, when the crosslinked structure (b) in which the crosslinking factor is a polyvalent metal ion compound is used as the synthetic polymer having a network structure, the compounding amount of the polyvalent metal ion compound depends on the gel. It is preferably 0.1 to 10% by mass. When the crosslinking factor is a polycarboxylic acid or a polyhydric alcohol, the blending amount of the polycarboxylic acid or the polyhydric alcohol is 0.1 to
It is preferably 5% by mass. When the crosslinkable factor is a polyfunctional epoxide or dialdehyde, the amount of the polyfunctional epoxide or dialdehyde is preferably 0.01 to 3% by mass based on the gel.

If the amount of the crosslinkable factor such as a polyvalent metal ion compound is less than the above range, the resulting synthetic polymer gel body has a low stiffness, and additives such as a solvent and a medicinal component encapsulated in the gel body. May be difficult to keep stable. Conversely, if the compounding amount exceeds the above range, the brittleness of the gel body increases, and there is a possibility that cutting or breaking may easily occur due to tensile stress or compressive stress.

The after-sun sheet may or may not have tackiness, but one surface of the sheet has weak tackiness and one surface is non-tacky, It is preferred that both surfaces have different degrees of adhesion. By treating one surface with a non-adhesive agent, it is possible to prevent the after-sun sheet from sticking to the hand during use, or to prevent the sheet from sticking to the tip of the finger and becoming entangled with the finger. As a method of non-adhesive treatment, for example,
It contains a cross-linking factor that increases the cross-linking density of the gel body by reacting with the synthetic polymer gel body. The surface of the treated body (hereinafter referred to as a non-adhesive surface) is not treated. A method of applying a material that can be reduced as compared with the other surface (hereinafter, referred to as an adhesive surface) (hereinafter, referred to as a non-adhesive treatment agent) may be used. Since the non-adhesive treating agent is characterized in that the cross-linking factor of the non-adhesive treating agent reacts with the gel to increase the crosslink density of the gel, the gel has a non-adhesive treating agent. A synthetic polymer capable of causing a crosslinking reaction with a crosslinking factor is required. Such a synthetic polymer may itself be a synthetic polymer having a network structure constituting a gel body, or separately from a synthetic polymer having a network structure constituting a gel body, its solvent may be contained in a gel body. In addition, an uncrosslinked synthetic polymer included in the gel body may be used.

As the combination of the above non-adhesive treating agent and the gel body, (c) polyvalent cations, polycarboxylic acids, polyhydric alcohols, The synthetic polymer comprising at least one crosslinking factor selected from the group consisting of functional epoxides and dialdehydes, and (d) a synthetic polymer having a network structure constituting a gel, comprises a carboxyl group, a sulfonic acid, Group having at least one functional group selected from the group consisting of a group, a hydroxyl group, an amide group, and an amino group;
A combination of a hydrophilic synthetic polymer obtained by polymerizing at least one kind of polymerizable unsaturated monomer (ie, a synthetic polymer capable of causing a cross-linking reaction with the cross-linking factor of the above (c)) is preferable. .

In the above (d), one or two or more polymerizable unsaturated monomers having at least one functional group selected from the group consisting of a carboxyl group, a sulfonic acid group, a hydroxyl group, an amide group and an amino group. The method in which the hydrophilic synthetic polymer obtained by polymerizing the monomer has a network structure includes, for example, (e)
A method of producing the copolymerizable unsaturated monomer together with a crosslinkable unsaturated monomer in addition to the polymerizable unsaturated monomer, and (f) a method of polymerizing the polymerizable unsaturated monomer and then preparing a polyvalent metal ion compound. ,
A method of producing a crosslinked structure by reacting with at least one type of crosslinkable factor selected from the group consisting of polyvalent carboxylic acids, polyhydric alcohols, polyfunctional epoxides and dialdehydes.

As described above, as the hydrophilic synthetic polymer having a carboxyl group in the side chain as described in the above (d), poly (meth) acrylic acid or a part or all of the carboxyl group may be sodium hydroxide or the like. And the like neutralized with an alkali. Examples of the hydrophilic synthetic polymer having a sulfonic acid group in the side chain include poly-t-butylacrylamide sulfonic acid and those obtained by neutralizing a part or all of the sulfonic acid group with an alkali such as sodium hydroxide.
Examples of the hydrophilic synthetic polymer having a hydroxyl group in a side chain include polyvinyl alcohol obtained by polymerizing and hydrolyzing a vinyl acetate monomer. Examples of the hydrophilic synthetic polymer having an amide group in a side chain include poly (meth) acrylamide, polyN, N′-dimethyl (meth) acrylamide, polyvinylpyrrolidone, and polyN-vinylacetamide. Examples of the hydrophilic synthetic polymer having an amino group in the side chain include polyallylamine, one in which some or all of the amino groups are neutralized with an acid such as hydrochloric acid, and polymethacryloyltrimethyloxyethylammonium chloride.

As described above, the monomers constituting the hydrophilic synthetic polymer include a carboxyl group, a sulfonic group,
In addition to a hydroxyl group, an amide group, and an amino group, it may have a functional group modified from these groups. For example, a treatment for esterifying about 40% of the hydroxyl groups or carboxyl groups in the hydrophilic synthetic polymer to make it lipophilic may be performed for the purpose of improving the adhesion to the skin. Further, when there is a long saturated hydrocarbon portion in the side chain, for the purpose of imparting hydrophilicity to the portion, further carboxyl group, sulfonic acid group,
You may introduce | transduce a hydroxyl group, an amide group, an amino group, etc., and may process with reagents, such as an acid and an alkali. These treatments may be performed before the polymerization of the monomer or after the polymerization.

As described above, the polymerizable unsaturated monomer described in (d) above includes (meth) acrylic acid (and its salt); t-butylacrylamide sulfonic acid (and its salt); Derivatives of (meth) acrylamide such as N, N'-dimethylacrylamide and dimethylaminopropylmethacrylamide; vinylpyrrolidone and the like;
It is suitably used from the viewpoint of easy production. The polymerizable unsaturated monomers may be used alone or as a mixture of two or more.

The crosslinkable unsaturated monomers described in the above (e) include, for example, N, N'-methylenebisacrylamide, N, N'-methylenebismethacrylamide, N, N ' -Ethylenebisacrylamide, N, N'-ethylenebismethacrylamide, 1,
2-diacrylamide ethylene glycol and the like.

As described above, examples of the crosslinkable factor (f) include polyvalent metal ion compounds, polyvalent carboxylic acids, polyhydric alcohols, polyfunctional epoxides, and dialdehydes.

Of these, as described above, examples of the polyvalent metal ion compound include an aluminum compound, a calcium compound, and a magnesium compound. Among them,
From the viewpoint of crosslinking efficiency, aluminum hydroxide and salts thereof, synthetic aluminum silicate, magnesium aluminate metasilicate, magnesium aluminum oxide, aluminum oxide, dihydroxyaluminum amino acetate, magnesium aluminum hydroxide carbonate hydrate, aluminum hydroxide carbonate Compounds containing trivalent aluminum ions such as sodium coprecipitate are preferred, and those having an amorphous structure are more preferred. Examples of the polycarboxylic acid include succinic acid, fumaric acid, phthalic acid, citric acid, malic acid and the like. Examples of the polyhydric alcohol include ethylene glycol, propylene glycol, butanediol, glycerin, diethylene glycol, diglycerin and the like. As the polyfunctional epoxide, for example, ethylene glycol diglycidyl ether, polyethylene glycol diglycidyl ether, propylene glycol diglycidyl ether, polypropylene glycol diglycidyl ether, polytetramethylene glycol diglycidyl ether, glycerol polyglycidyl ether, polyglycerol polyglycidyl ether, Examples include sorbitol polyglycidyl ether, sorbitan polyglycidyl ether, trimethylolpropane polyglycidyl ether, pentaerythritol polyglycidyl ether, resorcin diglycidyl ether, neopentyl glycol diglycidyl ether, and 1,6-hexanediol diglycidyl ether. Examples of dialdehydes include glyoxal, terephthalaldehyde, glutaraldehyde and the like.

In the case of producing by a copolymerization method (e) as a method having a network structure, the compounding amount of the crosslinkable unsaturated monomer is 0.005 to 0.5% by mass based on the gel body. Is preferred. If the amount is less than 0.005% by mass, it is difficult to obtain a gel having sufficient waist strength, and it may be difficult to stably maintain additives such as a solvent and a medicinal component contained in the gel. is there. Conversely, if the blending amount is 0.
If it exceeds 5% by mass, the brittleness of the obtained gel body increases,
Cutting or destruction may easily occur due to tensile stress or compressive stress.

On the other hand, as a method having a network structure, when the cross-linking factor is a polyvalent metal ion compound and the crosslinked structure (f) is produced, the compounding amount of the polyvalent metal ion compound is based on the gel body. It is preferably 0.1 to 10% by mass. When the crosslinking factor is a polycarboxylic acid or a polyhydric alcohol, the blending amount of the polycarboxylic acid or the polyhydric alcohol is preferably 0.1 to 5% by mass based on the gel body. When the crosslinkable factor is a polyfunctional epoxide or dialdehyde, the amount of the polyfunctional epoxide or dialdehyde is preferably 0.01 to 3% by mass based on the gel.

If the amount of the crosslinkable factor such as a polyvalent metal ion compound is less than the above range, the resultant synthetic polymer gel body has a low stiffness, and additives such as a solvent and a medicinal component encapsulated in the gel body. May be difficult to keep stable. Conversely, if the compounding amount exceeds the above range, the brittleness of the gel body increases, and there is a possibility that cutting or breaking may easily occur due to tensile stress or compressive stress.

The crosslinking factor described in (c) above includes, in addition to the polyvalent cations described below, polyvalent carboxylic acids, polyhydric alcohols, polyfunctional epoxides, and dialdehydes. Examples of the polycarboxylic acid include succinic acid, fumaric acid, phthalic acid, citric acid, malic acid and the like. Examples of the polyhydric alcohol include ethylene glycol, propylene glycol, butanediol, glycerin, diethylene glycol, diglycerin and the like. Examples of the polyfunctional epoxide include ethylene glycol diglycidyl ether, polyethylene glycol diglycidyl ether, propylene glycol diglycidyl ether, polypropylene glycol diglycidyl ether, polytetramethylene glycol diglycidyl ether, glycerol polyglycidyl ether,
Polyglycerol polyglycidyl ether, sorbitol polyglycidyl ether, sorbitan polyglycidyl ether, trimethylolpropane polyglycidyl ether, pentaerythritol polyglycidyl ether,
Examples include resorcin diglycidyl ether, neopentyl glycol diglycidyl ether, 1,6-hexanediol diglycidyl ether, and the like. Examples of dialdehydes include glyoxal, terephthalaldehyde, glutaraldehyde and the like.

Further, the hydrophilic synthetic polymer described in the above (d) and the above (c) for the non-adhesive treatment to be applied to one surface of a single synthetic polymer gel body for forming an after-sun sheet.
A preferred combination of the crosslinkable factors described above is obtained by polymerizing a polymerizable unsaturated monomer having at least an anionic functional group as such a hydrophilic synthetic polymer from the viewpoint that production is easier. Made of hydrophilic synthetic polymer,
In addition, a combination of those having at least a polyvalent cation is preferable as such a crosslinking factor.

The above-mentioned anionic functional groups are all functional groups capable of chemically bonding to cations in water. From the viewpoint of easy production, -COOH, -COOX
A carboxyl group represented by (X; counter ion) is preferred.

The above-mentioned polyvalent cations are all cations having two or more valencies, and for example, A
Trivalent or higher ions such as l ³⁺ , Fe ³⁺ , Ti ³⁺ , In ³⁺ , Zr ⁴⁺ , and Ta ⁵⁺ are preferable.

The form of the polyvalent cation may be a salt which is soluble in water such as aluminum chloride or a salt which is hardly soluble in water such as synthetic aluminum silicate. I don't care. The selection of the solubility / poor solubility of these salts selects the one most suitable for the production method. That is, if the purpose of such non-adhesive treatment is to be carried out immediately, it may be selected in the form of a salt which is soluble in the solvent contained in the selected non-adhesive treating agent or gel at that time. When the treatment is intended to be performed for, for example, one hour or more, a salt form that is hardly soluble in the solvent contained in the non-adhesive treatment agent or gel selected at that time may be selected.

The non-adhesive treating agent for treating one surface of a single synthetic polymer gel for forming an after-sun sheet may contain a solvent in addition to the above-mentioned crosslinkable factor. And monoalcohols such as ethyl alcohol, glycols such as 1,3-butylene glycol, and polyhydric alcohols such as glycerin. As described above, the crosslinking agent may be dissolved in such a solvent or may not be dissolved as in a slurry. Further, the non-adhesive treating agent may contain various additives as necessary.

The amount of the non-adhesive treating agent to be applied to the surface of the gel body is 1 × 10 ⁻¹⁰ equivalent / cm ² to 1 × 10 ^{−2 in} terms of the crosslinking equivalent of the crosslinking factor per square centimeter of the gel body surface.
It is preferably equivalent / cm ² . Processing amount is 1 × 10 ^-10
If it is smaller than the equivalent weight / cm ^2, the difference in adhesion between the non-adhesive surface and the adhesive surface does not appear remarkably, and handling during use becomes poor. When the processing amount is larger than 1 × 10 ^-2 equivalent / cm ² , the non-adhesive treatment of the non-adhesive surface is sufficiently performed,
It does not work any more. Here, the cross-linking equivalent of the cross-linking factor refers to the amount of the cross-linking points of the cross-linking factor expressed in moles.

When a non-adhesive treating agent is applied to one surface of a single synthetic polymer gel for forming an after-sun sheet,
Such a surface may be treated on one side with a uniform treatment amount, or the treatment amount may be partially non-uniform. Therefore, the surface may be non-uniformly treated within the above-mentioned preferable treatment amount.

Regarding the thickness of the sheet used in the present invention,
The thickness may be set appropriately according to the use condition, and may be uniform throughout or partially different in thickness.
It is preferably in the range of 1 to 10 mm, more preferably 0.5 to 5 mm. If the thickness of the entire sheet is less than 0.1 mm, the strength of the aftersun sheet becomes weak, and the cooling effect becomes weak. On the other hand, if it exceeds 10 mm, the weight of the sheet becomes too large, and there is a problem that the sheet does not adhere to the skin.

In the after-sun sheet used in the present invention, the after-sun sheet is provided inside the gel body for the purpose of improving the tear strength and handleability thereof without impairing the transparency of the after-sun sheet. A knitted or nonwoven fabric having a sufficiently large opening ratio is included in the thickness direction. The term “inherited” as used herein means, besides the one that is present in the substantially intermediate layer in the thickness direction of the gel body, the one that is impregnated in the surface layer of the gel body.

The knitted woven fabric or nonwoven fabric having a sufficiently large opening ratio means a material having a wide opening ratio (maintaining transparency) so that 10-point black print can be read through the woven fabric or nonwoven fabric. Say.

In the present invention, in addition to the above-mentioned system using the synthetic polymer, conventionally known viscosities such as carrageenan, xanthan gum, gellan gum, agar, gelatin, kuzu, macrohomosis gum, hydroxyethylcellulose and carboxymethylcellulose can be used. It is also possible to carry out formulation using the agent alone or in combination with a synthetic polymer. In this case, an aqueous solution of these adhesives is prepared by heating or using a microwave oven, and is applied to a transparent resin film or the like, or is applied to a woven or nonwoven fabric having a sufficiently large opening ratio, or Impregnation to form a film. At this time, the use of the blister has an advantage that the production can be facilitated.

The after-sun sheet of the present invention can contain various additives in addition to the above-mentioned various components. For example, a thickener, a fragrance, a colorant, a stabilizer, an antioxidant, an ultraviolet absorber, a tackifier, a pH adjuster, a chelating agent, a surfactant and the like can be mentioned.

As the thickening agent, those having a relatively small amount and a certain viscosity of the mixed liquid are preferable, and examples thereof include water-soluble polymers such as polyethylene oxide and hydroxyethyl cellulose.

In the present invention, it is preferable to provide a liquid layer containing the above-mentioned various components, particularly water or water and a humectant, on the surface of the sheet. The liquid layer may be provided by a post-treatment of applying or spraying a liquid component on the sheet, or after forming a gel, applying a salt of the non-adhesive treating agent to the sheet surface,
The liquid component may be provided by bleeding from the inside. Further, a liquid layer may be formed by applying or spraying water or a liquid containing water and a humectant on the sheet surface when the sheet is used. The former two have the merit that there is a great degree of freedom when preparing a formulation, but the problem is that the manufacturing process becomes longer, and the latter has the merit that the manufacturing is easy, but the problem that the degree of freedom in the formulation is reduced. Yes, it is preferable to appropriately select these steps while checking the characteristics and size of the preparation.
Further, the liquid layer may contain a tackifier and an adhesive component which can be used in cosmetics. By providing a liquid layer on the surface of the sheet preparation in this way, a cool feeling can be felt more strongly.

The following is an example of the method for producing the aftersun sheet of the present invention. In the after-sun sheet, the synthetic polymer having a network structure constituting the gel body is (a) a copolymer of one or more polymerizable unsaturated monomers and a cross-linkable unsaturated monomer. Or (b) having at least one functional group selected from the group consisting of a carboxyl group, a sulfonic group, a hydroxyl group, an amide group, and an amino group on the side chain;
From a hydrophilic synthetic polymer obtained by polymerizing one or more polymerizable unsaturated monomers and a polyvalent metal ion compound, a polycarboxylic acid, a polyhydric alcohol, a polyfunctional epoxide and a dialdehyde At least one selected from the group consisting of
It is preferably a crosslinked structure obtained by reacting with a kind of crosslinking factor.

When the copolymer of the polymerizable unsaturated monomer and the crosslinkable unsaturated monomer (a) is used as a synthetic polymer having a network structure, a method for producing a gel is as follows. For example, a method in which a polymerizable unsaturated monomer, a crosslinkable unsaturated monomer, and a polymerization initiator are added to a solvent constituting a gel to carry out polymerization. For the polymerization, a system in which the polymerization is started by heating or light irradiation or by adding a polymerization initiator may be selected.

On the other hand, when the crosslinked structure obtained by reacting the hydrophilic synthetic polymer of (b) with a crosslinkable factor is used as a synthetic polymer having a network structure, a method for producing a gel body includes the following: For example, there is a method in which a hydrophilic synthetic polymer polymerized in advance in the same manner as described above is dissolved, and a crosslinking reaction is performed by adding a crosslinking factor to the solution. The cross-linking reaction may be started by heating or may be started by adding a reaction initiator. Alternatively, a system in which a crosslinking reaction starts immediately upon addition of a crosslinking factor may be selected.

In the case where a gel is obtained by polymerizing the unsaturated monomer in the above (a), when thermal polymerization is carried out using a solution containing the above-mentioned monomer and solvent, azobiscyanovaleric acid or Azo-based polymerization initiators such as azobisaminopropane dihydrochloride, or reducing agents such as ferrous sulfate, dithionite, pyrosulfite and hydrogen peroxide, t-butyl hydroperoxide, peroxodisulfate The polymerization can be carried out by adding a redox polymerization initiator comprising a peroxide such as These azo-based polymerization initiators and redox-based polymerization initiators may be used alone or in combination as needed. In the case where a redox polymerization initiator is used, a system in which polymerization is initiated only by adding it without heating may be used. In the case of photopolymerization, photo-radical polymerization initiators such as acetophenone-based, benzoin ether-based, phosphorus-based, benzophenone-based, thioxanthone-based, and azo-based, and photocationic polymerization such as diazonium salts, diallyliodonium salts, and triarylsulfonium salts. Polymerization can be carried out by adding an initiator or the like.

The thickness of the after-sun sheet is adjusted by, for example, using an extruder or a doctor blade or the like to spread the gel-forming composition before the curing of the gel body, or by adjusting the thickness to a predetermined thickness. This is performed by filling a container having the composition, for example, a blister container.

In the latter method of filling a container having a predetermined thickness, if the shape of the concave portion of the container is formed according to the shape of the after-sun sheet at the time of use, the in-line manufacturing process becomes easy, This is preferable in the manufacturing process. Furthermore, compared with the method of forming a long belt-like gel body and punching it into the intended shape at the time of use, the amount of gel to be discarded is reduced, and since there is no contact between the gel body and the punching blade, sanitary It is also preferable from the viewpoint of being appropriate.

As a method of treating one surface of the after-sun sheet with the above non-adhesive treating agent, (i) after the curing of the gel body is completed, treating the surface with the non-adhesive treating agent. Before the curing of the gel body (j), the surface thereof may be treated with a non-adhesive treating agent. In addition, "the completion of the curing of the gel body" in the present invention means that the compound before gelation has undergone a gelling reaction and is in a state having shape retention.

The manufacturing method in the case of the above (i) is as follows. One surface of the cured gel body is coated with, for example, a coater,
A method of applying a non-adhesive treatment agent by a method such as coating using a printing machine, brush or the like, or spraying using a spray or the like is preferable.

In the case of the above-mentioned method (j), a method for preparing a gel-forming composition before the completion of curing, the thickness of which has been adjusted by the above-described method, may be applied, for example, by using a coater, printing machine,
A method of applying a non-adhesive treatment agent by a method such as coating using a brush or spraying using a spray or the like is preferable.

However, as the production condition in the case of the above (j), the gel-forming composition when one of the surfaces of the gel-forming composition before the curing is treated with a non-adhesive treating agent is not less than a certain amount. It is desirable to have a viscosity. The viscosity is preferably 1,000 centipoise or more. That is, when the viscosity of the gel-forming composition when treated with the non-adhesive treating agent is smaller than 1,000 centipoise, the gel-forming composition and the non-adhesive treating agent are mixed,
The effect of the non-adhesive treating agent acts on the other surface that has not been treated, and as a result, there is a possibility that there is no difference in the degree of adhesion between both surfaces of the manufactured aftersun sheet.

As a manufacturing method in the case of the above (j),
When adjusting the thickness of the gel-forming compound before the end of curing,
By applying a non-adhesive treating agent to such a gel-forming composition, it is possible to cause a difference in the degree of adhesion between both surfaces of the manufactured aftersun sheet. That is, when adjusting the thickness of the gel-forming composition before the completion of curing, a sheet capable of interposing a non-adhesive treating agent (hereinafter, referred to as an interposed sheet), interposing the non-adhesive treating agent on one surface, After placing the intervening sheet on the gel-forming composition before the completion of the curing, the thickness of the gel-forming composition before the completion of the curing is adjusted using a doctor blade, a squeegee, or the like. As a result, the non-adhesive treating agent held by the interposed sheet can be transferred to the gel-forming composition, and this is allowed to stand until the completion of the curing of the gel body, whereby the desired adhesion of both surfaces is achieved. Aftersun sheets of different degrees can be obtained.

In the case of such a production method, the viscosity of the gel-forming composition immediately before the thickness adjustment is performed is 10,000 to 2,000.
Preferably, it is 0.000 centipoise. That is, if it is smaller than 10,000 centipoise, the gel-forming composition and the non-adhesive treating agent mix, and the effect of the non-adhesive treating agent acts on the other untreated surface. There is a possibility that no difference occurs in the degree of adhesion between both surfaces of the after-sun sheet.
Also, if it is larger than 2,000,000 centipoise,
It becomes difficult to adjust the thickness of the gel-forming composition itself.

The interposed sheet may be any sheet as long as the non-adhesive treating agent can be interposed on one side, and examples thereof include a plastic sheet, a sponge sheet, paper, a woven fabric, and a nonwoven fabric. The intervening sheet is
To peel off the after-sun sheet before use,
A plastic sheet or the like that is easy to peel off is preferable.

In order to make the non-adhesive processing agent easily intervene in the interposed sheet, a thickener can be added to the non-adhesive processing agent.

Until the sheet for after sun is used, at least the plastic film such as polyethylene, polypropylene, polyethylene terephthalate or the like is left as it is on the adhesive side, or the surface of the plastic film is released from the mold such as silicone resin. It is necessary to paste it as release paper with the agent applied or baked
Sanitary preferred. In addition, it is preferable to adhere the release paper to the non-adhesive side from the viewpoint of preventing drying of the after-sun sheet and hygiene considerations.

It is preferable to peel off the release paper that has been pasted when it is used, because the release paper is not flexible enough to follow the movement of the fingertip. If the release paper is used with the release paper adhered to the non-adhesive surface, the release paper will peel off from the after-sun sheet during use, making it difficult to handle. The release paper may be used as an underlay or a surface material during the gel production process of the after-sun sheet, or may be attached after the production of the after-sun sheet is completed.

The shape of the after-sun sheet of the present invention is not particularly limited, but may be a rectangle, a rectangle having a rounded corner, a circle, an ellipse, or a shape along the surface of a nose. A rectangle is preferable because it has less waste during molding.

As a method of using the after-sun sheet of the present invention, first, the affected part is thoroughly washed with running water to remove dirt such as sand, then the water is lightly pushed out, and the sheet is adhered from above. No. This sheet is preferably designed so that when the gel loses its water-holding power and loses its cooling effect, it loses its adhesion to the skin and peels from itself. In this case, there is an advantage that the damaged skin can be removed without imposing a load. Furthermore, if the T-shirt or the like is brought into direct contact with the tanned skin, rubbing or the like may occur on the affected area and the inflammation may worsen. If this sheet is used, wear the T-shirt or the like from above. Also, the cushioning properties of the seat have the effect of minimizing the stimulation of the affected area.

[0078]

The present invention will be described in more detail with reference to the following Examples and Comparative Examples. The evaluation methods used in the examples and comparative examples are as follows.

[Evaluation of Skin Utility] Ten expert panelists were prepared for each evaluation item (however, panelists may be duplicated depending on the item), and evaluation was performed according to the evaluation criteria shown in Table 1. The total score was used as the evaluation result. Therefore, the higher the score, the higher the usefulness for the evaluation item. (Score: 50 points) After the sample was tanned in the sea bath and pool in Okinawa and the Kanto region in June and July 2000, it was continuously applied to the shoulder for 3 days.
It was used a total of four times (twice on the first day), and evaluated on a questionnaire on the third day and one week later.

[Table 1] Reference points --------------------------------------- ------ The effect seems to be high 5 The effect is felt 4 The effect is slightly felt 3 The effect is slightly felt 2 The effect is not felt 1

Example 1 An after-sun sheet was produced by the following production method. Table 2 shows the compositions of the gel-forming compound and the non-adhesive treating agent of a single synthetic polymer gel to form an after-sun sheet. This after-sun sheet cools and sterilizes the affected area immediately after application by blending moisturizing and sterilizing components into the surface water, then evaporates the moisture of the gel, as well as the anti-inflammatory component, moisturizing component, and radical scavenger inside the gel. The skin lightening component and the cell growth active component are designed to diffuse gradually to the skin to exert a lasting effect.

[Table 2] Composition mass% -------------------------------------- ------------------------------ <Formation compound for gel formation> Polymerizable unsaturated monomer Acrylic acid 25.0 Crosslinking Unsaturated monomer N, N'-methylenebisacrylamide 0.1 Polymerization initiator 4% aqueous solution of ammonium persulfate 5.0 2% aqueous solution of potassium pyrosulfite 5.0 pH adjuster 10% aqueous solution of sodium hydroxide 40.0 Humidity Glycerin 10.0 Triethylene glycol 10.0 Antimicrobial agent Methyl parahydroxybenzoate 0.3 Active ingredient Soluble eggshell membrane 2.0 Anti-inflammatory agent Dipotassium glycyrrhizinate 0.1 Whitening agent / radical scavenger Placenta extract 0.1 Licorice Extract (water / ethanol extraction, dry residue 4.5%) 0.1 hinokitiol 0.1 camphor 0.1 l-menthol 0.2 purified water residue Amount Total 100.0 <Non-adhesive treating agent> Crosslinking factor Aluminum chloride hexahydrate (Al content: 11%) 1.0 Solvent Ethyl alcohol 50.0 Physiologically active ingredient Aloe extract (water / PG extraction, dried residue) 2.0 peach leaf extract (water, 1,3-BG extraction, dry residue 1.6%) 1.0 Purified water residue Total 100.0

The components excluding the polymerization initiator (4% aqueous ammonium persulfate solution and 2% aqueous potassium pyrosulfite solution) in the gel-forming composition shown in Table 2 were purified water and glycerin and triethylene glycol (humectant) as solvents. Then, the polymerization initiator was added, and the mixture was stirred well to obtain a gel-forming composition. Next, a spacer having a thickness of 1.9 mm is placed on a polyethylene terephthalate sheet (thickness: 50 μm) having a surface baked with a silicone resin (release agent), and the gel-forming composition is provided in a range surrounded by the spacer. Was poured. In addition, a 15-denier nylon tulle woven cloth (having a sufficiently large opening ratio) is provided on the middle layer in the thickness direction of the gel-forming composition.
Was immersed. Further, the surface of the compound is covered with a polyethylene terephthalate sheet (thickness: 100 μm) having a surface baked with a silicone resin (release agent), and heated at 70 ° C. for 5 minutes to perform polymerization, thereby forming a gel. The curing was terminated to form a synthetic polymer gel body.

From the above synthetic polymer gel, 100 μm thick
m polyethylene terephthalate sheet was peeled off, and a non-adhesive treating agent in which a crosslinking factor (aluminum chloride hexahydrate) shown in Table 2 was dissolved in a solvent (ethyl alcohol and purified water) was applied to the peeled gel body surface. The mixture with the active ingredient was uniformly applied using a brush and applied at 40 mg / cm ² (that is, 1 × 10 ⁻⁵ equivalent / cm ^{2 in} terms of crosslinking equivalent). By performing this treatment, it was confirmed by the wetness of the filter paper and the chemical analysis that water was squeezed out on the surface of the gel body. Further, a 50 μm-thick polypropylene sheet was placed on the surface of the gel body treated with the non-adhesive treating agent, and the gel body was punched into a 10 cm × 7.5 cm rectangle with rounded corners. Subsequently, the sheet was put into an aluminum sheet having high moisture impermeability to obtain an intended final product.

Comparative Example 1 A commercially available spray-type lotion for after sun was used as a comparative example.

Table 3 shows the evaluation results of the examples and the comparative examples.

[Table 3] Transparency Cool feeling Improvement of inflammation Less burden on skin Suppression of pigmentation ---------------------------- --------------------------------------- Example 1 Transparency 50 45 45 37 Comparative Example 1 −36 38 43 26

From the results shown in Table 3, it can be seen that the examples of the present invention are excellent in sustained cooling sensation, excellent in the effect of improving inflammation, less burden on the skin, and have the effect of suppressing pigmentation as compared with the comparative example. I understand. On the other hand, Comparative Example 1 is a commercially available spray-type lotion for after sun, but the cooling effect was weak and the inflammation was not easily felt. Moreover, the thing of Example 1 was popular because the external appearance was transparent and the feeling of incongruity at the time of use was small, and the state of the skin could be observed.

[0089]

From the above results, it can be seen that the present invention uses a sheet-form preparation excellent in cooling effect and replenishing ability of moisture and moisturizer, soothes skin inflammation after sunburn, and alleviates pigmentation. It is clear that the present invention provides an excellent after-sun sheet.

 ──────────────────────────────────────────────────続 き Continuing on the front page (72) Inventor Yasushi Yasushi 7-33, Oanji, Nara City, Nara Prefecture 4C076 AA72 BB31 CC04 CC18 CC31 DD23 DD30Z DD37 DD38 EE09 EE26 FF68 4C083 AA072 AA112 AB032 AB051 AB332 AC102 AC112 AC122 AC482 AD092 AD532 AD552 BB41 CC19 DD12 EE13 EE16 EE17

Claims (6)

[Claims] 1. A sheet-like preparation comprising a hydrogel having a transparent or translucent appearance, wherein a woven or nonwoven fabric having a sufficiently large opening ratio is provided inside the sheet in the thickness direction. Characteristic after-sun sheet. 2. The after-sun sheet according to claim 1, wherein the sheet contains a moisturizing component. 3. The after-sun sheet according to claim 1, wherein the sheet contains an anti-inflammatory component and / or an anti-bacterial component. 4. The after-sun sheet according to claim 1, wherein the sheet contains a whitening component and / or a radical scavenger component. 5. The after-sun sheet according to claim 1, wherein a surface of the sheet is covered with a liquid component containing water. 6. The after-sun sheet according to claim 1, wherein the surface of the sheet is covered with a liquid component containing water at the time of use.