JP2002045678A - Ejecting tool and communicating device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an ejecting tool and a communicating device which can divide a prescribed amount of a liquid from a vessel of one side and can easily eject the liquid while preventing pollution with microorganism. SOLUTION: The ejecting tool 1 is provided with a hollow needle 7 and a regulation section 9. The hollow needle 7 has a liquid ejection section 3 at one end side and a transfixion section 5 with which a stopper body 16 of a first vessel 10 can be pierced at another end side and further has an ejecting opening 4 and a piercing opening 6 which are communicated with the liquid ejection section 3 and the transfixion section 5 through a communicative path 8. The regulation section 9 regulates piercing quantity of the transfixion section 5 to the stopper body 16 of the first vessel 10 by being fixedly provided at the hollow needle 7 and being restrained by a restraining section 15 in a piercing direction. When the regulation section 9 is restrained by the restraining section 15, the piercing opening 6 is made to be away from a bottom part at the time of ejecting the liquid in a housing chamber 12 of the first vessel 10.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a discharge tool for dividing and discharging a part of a liquid contained in a first container, and more particularly to a method for disassembling a sterile liquid contained in a first container into plural parts. The present invention relates to a discharge tool suitable for dividing and discharging a second container, and a communication device using the same.

[0002]

2. Description of the Related Art Some liquids, such as pharmaceuticals and foods, which are liable to be contaminated by microorganisms when exposed to outside air, may be used by mixing a plurality of such liquids as necessary. For example, in the case of pharmaceuticals, if the drug efficacy is reduced if they are mixed in advance, or if an appropriate amount is mixed and administered depending on the patient, a plurality of drugs are mixed at the time of use. Such liquids are stored in separate sealed containers before use, and when used, the contents are weighed from some containers and transferred to other containers for mixing, It is used by communicating between the accommodation chambers using a discharge tool, transferring the contents of some containers to another container, and mixing. When the content of some containers is powder, the solution is used by dissolving the solution in a container containing the powder and then mixing the solution with the liquid to be mixed in another container. ing. As a container for such an infusion solution or the like, a vial or a flexible bag whose storage chamber is sealed with a plug through which a hollow needle can be pierced is used. Syringes are often used to transfer. Further, instead of using a syringe, a combination of a discharge device and a container is also used. Examples of such a discharge device include a hollow needle connected to one container and a double-ended needle disposed between the containers. Is used. Further, in recent years, a multi-chamber container having a multi-chamber partitioned by an openable partition wall has been used. In such containers and ejectors that have been used in the past, prevention of microbial contamination has been considered as a priority, so each container usually holds a single use amount, The whole amount is mixed by using. However, there is a case where the content is used less than the content of each container at the time of mixing. . Therefore, it is necessary to weigh correctly at the time of mixing, so that the mixing work is troublesome, and if a weighing error occurs, an improper amount is administered to the patient, which is likely to cause a medical error. However, there is a problem in that it is liable to be contaminated by microorganisms during the mixing operation because it is taken out of the container and transferred to another container.

[0003] When used in this way, the residual liquid is usually disposed of because there is a risk of microbial contamination if it is used again. However, if the sterility can be ensured until the next use after one use, or if the use interval is short and there is little risk of contamination by microorganisms, the contents of one container should be It is possible to use it separately. As such a substance that may be divided and used, for example, a vitamin preparation and the like can be mentioned. The vitamin may be administered alone to the patient, or may be administered in an appropriate amount depending on the patient, mixed with a high-calorie infusion or other drug solution. Conventionally, high-calorie infusions were mixed with multivitamin preparations before administration, but the use of excess vitamin preparations was temporarily mixed, and the Ministry of Health and Welfare restricted their use. However, in recent years, it has been found that acidosis is likely to occur unless vitamin B1 and other vitamins are mixed with high-calorie infusion, and vitamins are now mixed in an amount suitable for high-calorie infusion therapy. High-calorie infusions are usually given to patients twice daily after surgery, but the currently approved and widely used volume of vitamins is about half the amount of vitamins contained in the container. It is also used by mixing with a high calorie infusion and mixing the remaining fluid with an infusion to be administered next time. Even when divided and used in this way, the entire amount of the prescribed amount of vitamin preparation contained in the container is administered. However, in order to divide and use a drug solution using a currently commercially available container, the operation is complicated as described above because of using a syringe and the like, and there is a high possibility of contamination by microorganisms. Further, the container is used after the first use. Since the remaining amount is different every time, if a wrong container is used at the time of the second mixing, there is a high possibility that a medical error such as the inability to administer a predetermined amount in two times will occur.
In recent years, in medical containers, systems for minimizing medical errors have advanced, and technologies such as so-called double bags have been established as systems to prevent medical errors in mixing high-calorie infusions. A system to prevent medical mistakes when mixing with an infusion has not yet been established.

[0004]

SUMMARY OF THE INVENTION The present invention has been made to solve the above-mentioned conventional problems, and it is intended to easily discharge a predetermined amount of liquid from one container while preventing contamination by microorganisms. It is an object of the present invention to provide a discharge device and a communication device that can perform the discharge.

[0005]

According to a first aspect of the present invention, there is provided an ejector for accommodating a liquid, the liquid being supplied from a storage chamber of a first container having an opening sealed by a pierceable plug. A discharge device for discharging, comprising a liquid discharge portion on one end side and a piercing portion capable of piercing the plug of the first container on the other end side, A hollow needle having a discharge opening and a piercing opening communicating with the communicating portion by a communication passage, respectively, and the first container provided fixed to the hollow needle and locked in a piercing direction by a locked portion. A regulating portion for regulating an amount of the piercing portion penetrated into the stopper body, wherein the piercing opening is formed in the first chamber when the regulating portion is locked by the locked portion. The discharge chamber is separated from the bottom at the time of discharge, and the volume of the storage chamber from the piercing opening to the bottom at the time of discharge becomes a predetermined amount. Characterized in that it is arranged at a position.

According to the present invention, the discharge opening at one end is set in a discharge state, and the piercing portion at the other end is pierced through the plug of the first container and fixed to the hollow needle. By locking the restricting portion to the stabbed portion, the piercing opening of the hollow needle is disposed at the discharge position in the storage chamber of the first container, and the liquid in the storage chamber of the first container is discharged. At this time, the puncturing opening of the hollow needle is disposed at a predetermined discharge position separated from the bottom of the storage chamber of the first container when the container is used by locking the restricting portion to the locked portion. Since the volume of the storage chamber from the position to the bottom at the time of discharge is a predetermined amount, when the liquid in the storage chamber of the first container is discharged, the liquid from the initial liquid level to the discharge position is discharged, An amount of liquid can be left in the first container. Therefore, a predetermined amount of liquid can be discharged by discharging the liquid remaining in the first container from the bottom at the time of use next time, and the liquid in the storage chamber of the first container is divided and discharged. Can be. In addition, in each of the above-described discharging operations, the liquid can be discharged from the first container without using other members, and the liquid and the discharging tool can be exposed to the outside air because the housing is always sealed by the stopper. Can be minimized. Therefore, since no special operation such as weighing is performed, the liquid in the storage chamber of the first container can be easily divided and discharged equally or unequally, and there is a danger of being contaminated by outside air. Since the amount is small, the liquid can be easily aseptically discharged.

According to a fourth aspect of the present invention, there is provided a communication apparatus for accommodating a liquid and accommodating a first container accommodating a liquid and having an opening sealed by a pierceable plug. And a plurality of discharge tools for discharging the liquid in the first container to the second container by communicating with the second container. A discharge opening having a liquid discharge portion communicating with the chamber, having a piercing portion on the other end side through which the plug of the first container can be pierced, and communicating with the liquid discharging portion and the piercing portion through a communication passage; And a hollow needle having a piercing opening, respectively, and the piercing portion of the piercing portion is provided fixed to the hollow needle, and is locked in the piercing direction by the locked portion. With a regulation unit that regulates the amount of piercing,
When the restricting portions of the plurality of discharging tools are locked to the locked portions, the piercing openings are respectively arranged at different discharging positions in the piercing direction in the second container, and at least one discharging position is in the second position. The first container is separated from the bottom portion at the time of discharge, and the volume of the storage chamber of the first container between the different discharge positions is a predetermined amount.

[0008] According to this communication device, since the plurality of discharge tools include the same discharge tool as the discharge tool of the first aspect, the liquid discharge section at one end is connected to the accommodating chamber of the second container. If the storage chamber of the first container and the storage chamber of the second container are communicated with each other, the liquid in the storage chamber of the first container is discharged to the storage chamber of the second container in the same manner as the discharger. be able to. Moreover, in this communication device, when the restricting portions of the plurality of discharging tools are locked to the locked portions, the piercing openings are respectively arranged at different discharging positions in the piercing direction in the second container, and at least one piercing opening is provided. The two discharge positions are separated from the bottom of the first container at the time of discharge, and the volume of the storage chamber of the first container between the different discharge positions is a predetermined amount. When the liquid in the storage chamber of the first container is discharged to the second container by using the discharge tool whose position is the highest position in the first storage chamber, from the liquid level at the time of discharge to the discharge position of this discharge tool The amount of liquid corresponding to the volume of the first container can be discharged to the second container, and the remaining liquid can remain in the storage chamber of the first container. Then, after releasing the communication state between the first container and the second container by the discharging device having the highest discharging position, the discharging position is different from the discharging device, and the first container is accommodated between the discharging positions. Using another discharging tool having a predetermined volume of the chamber, the first container is communicated with another second container in the same manner as described above, and the liquid in the storage chamber of the first container is discharged. Then, the predetermined amount of liquid can be discharged to another second container. Therefore, since a special operation such as weighing is not performed, the liquid in the storage chamber of the first container can be easily divided into equal or unequal portions and discharged into the storage chambers of the plurality of second containers. Since it is possible and the risk of contamination by outside air is small, the liquid can be easily aseptically discharged and distributed to the plurality of second containers.

In the communication device according to a sixth aspect of the present invention, the storage chamber for the first container and the storage chamber for the second container, each of which contains a liquid and whose opening is closed by a pierceable plug, are provided. And a discharge device for discharging the liquid in the first container to the second container by communicating with a liquid discharge unit that communicates with the storage chamber of the second container on one end side. A hollow having a piercing portion on the other end side through which a plug of the first container can be pierced, and having a discharge opening and a piercing opening respectively connected to the liquid discharging portion and the piercing portion by a communication passage; A needle, and a restricting portion fixed to the hollow needle and configured to lock the locked portion in the piercing direction to control the amount of the piercing portion penetrated into the plug of the first container. And a piercing opening different from the piercing direction when the regulating portion is locked to the locked portion. Displacing means for disposing at least one discharge position at a discharge position and separating at least one discharge position from a bottom portion of the first container at the time of discharge, wherein the volume of the accommodation chamber of the first container between the different discharge positions is a predetermined amount. It is characterized by becoming.

[0010] According to this communication device, since the same discharge device as that of the first aspect is included, the liquid discharge portion at one end is connected to the accommodating chamber of the second container so that the first container is connected to the first container. If the storage chamber of the first container is communicated with the storage chamber of the second container, the liquid in the storage chamber of the first container can be discharged to the storage chamber of the second container in the same manner as in the discharge tool. Moreover, in this communication device, when the restricting portion is locked to the locked portion, the piercing opening is arranged at a different discharging position in the piercing direction, and at least one discharging position is set at the time of discharging the first container. It has a displacement means for separating from the bottom, and the volume of the storage chamber of the first container between the different discharge positions is a predetermined amount, so that the discharge position becomes the highest position in the first storage chamber at the time of discharge. Thus, the liquid in the storage chamber of the first container is
When the liquid is discharged to the second container, an amount of liquid corresponding to the volume of the first container from the liquid level at the time of discharge to the discharge position of the discharging tool can be discharged to the second container, and the remaining liquid is discharged to the second container. It can remain in the accommodation room of one container. Then, after releasing the communication state between the first container and the second container where the discharge position is the highest position at the time of discharge, the discharge position is different from the position by the displacement means, and the first position between the discharge positions is changed.
Using the same or different discharge tools whose discharge positions are displaced so that the volume of the storage chamber of the container becomes a predetermined amount, the first container and another second container are communicated in the same manner as described above. ,
If the liquid in the storage chamber of the first container is discharged, the predetermined amount of liquid can be discharged to the second container. Therefore, since a special operation such as weighing is not performed, the liquid in the storage chamber of the first container can be easily divided into equal or unequal portions and discharged into the storage chambers of the plurality of second containers. Since it is possible and the risk of contamination by outside air is small, the liquid can be easily aseptically discharged and distributed to the plurality of second containers.

In this communication device, the displacement means may include a plurality of pierceable plugs for sealing a plurality of openings provided in the first container.
Since different plugs are used when discharging separately, each plug can be kept in an aseptic condition until use, and even if the hollow needle is pierced, the plug contaminated by microorganisms can be removed. Microbial contamination of the piercing portion due to contact does not occur, and microbial contamination of the liquid stored in the first container through contamination of the piercing portion can be prevented. Further, in this communication device, when the displacement means includes a spacer interposed between the locked portion and the regulating portion, the discharge position of the discharge tool can be easily adjusted by adjusting one or more spacers. It is adjustable and the amount of liquid discharged from the first container is easily adjusted.

[0012]

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is an exploded perspective view of a discharge device according to the present invention. FIGS. 1A and 1B are cross-sectional views showing a state of discharging a liquid according to an embodiment of the discharging device of the present invention. In the drawing, reference numeral 1 denotes a discharge tool of this embodiment, which is a member for discharging the liquid in the storage chamber 12 of the first container 10. The first container 10 is a soft container such as a resin bag, a hard container such as a glass bottle, and the like. The accommodation room 12 accommodates a liquid that may be contaminated by microorganisms, for example, a chemical solution such as a vitamin solution. ing. The liquid medicine may be stored in advance, but powder such as a freeze-dried product is stored in advance, and when used, a solution or a liquid in another container is injected to dissolve or disperse the liquid. May be used. The container opening 14 of the first container 10 can be pierced with a sharp needle, and when the needle is pulled out, it is sealed by a plug 16 such as a rubber stopper made of a material capable of closing the piercing hole by its own elasticity. It is fixed to the container opening 14 by being covered with an aluminum cap 17 or the like. Therefore, the inside of the accommodation room 12 is maintained in a sterile state, and the outer surface is also maintained in a sterile state before use. The discharging device 1 includes a hollow hollow needle 7 having a liquid discharging portion 3 on one end side and a piercing portion 5 which can pierce the stopper 16 of the first container 10 on the other end side. I have. The hollow needle may be made of metal or resin, but is preferably made of resin because disposal after use is easy. A communication passage 8 is formed inside the hollow needle 7 in the longitudinal direction, and a discharge opening 4 is formed in the liquid discharge portion 3 as both ends of the communication passage 8.
However, the piercing portion 5 is provided with a piercing opening 6, and both are communicated by the communication passage 8. On the outer periphery of the intermediate portion of the hollow needle 7,
A locked portion 15 formed of the top of the first container 10 and a locking portion 9 that can be locked are fixedly provided. This regulation part 9
May be formed integrally with the hollow needle 7,
It may be attached immovably by engaging means such as welding or bonding. The restricting portion 9 has an end surface 9 on the piercing portion 5 side.
When a contacts the top surface 15 in the piercing direction, the amount of piercing that penetrates the piercing portion 5 into the stopper 16 of the first container 10 and enters the housing chamber 12 is regulated.

Here, the locked portion 15 is not particularly limited as long as it can be locked by moving the restricting portion 9 in the piercing direction. May be a part of another member attached to the first container, or a part of a member provided in another container connected to the first container. In addition, before use, the first container 10 and the discharging device 1 are kits that combine the discharging device 1 and the first container 10 or other containers even if they are independent members. It may be. further,
For the purpose of improving workability when piercing the hollow needle 7 into the plug 16 of the first container 10 and preventing the occurrence of coring at the time of piercing, the hollow needle 7 is discharged at the time of piercing the hollow needle 7. A guide for guiding the relative movement between the tool 1 and the first container 10 in a predetermined direction may be provided. In this case, for example, the first container 1 or a member directly or indirectly fixed to the first container, and the discharging tool 1 or a member directly or indirectly fixed to the discharging tool 1,
The hollow needle can be slid so as to linearly move relative to the orientation direction.

In order to discharge the liquid in the storage chamber 12 of the first container 10 by using such a discharging tool 1, the piercing portion 5 is pierced through the plug 16 of the first container 10. When the hollow needle 7 penetrates into the first container 10 to a predetermined depth, the regulating portion 9 fixed to the hollow needle 7 abuts on the stabbed portion 15 and is locked. Thereby, the piercing opening 6 of the hollow needle 7 can be arranged at the predetermined discharge position S inside the first container 10. In this state, when the stopper 16 is turned downward and the discharge opening 6 at one end of the discharge tool 1 is set in the discharge state, the liquid in the storage chamber of the first container can be discharged. When the liquid in the storage chamber 12 of the first container 10 is discharged in this manner, the puncturing opening 6 of the hollow needle 7 is locked in the first container 10 by locking the regulating portion 9 to the locked portion 15. The discharge position S which is separated from the position of the stopper 16 serving as the bottom when the storage chamber 12 is used.
And from the discharge position S to the plug 1
Since the volume of the storage chamber 12 up to the position 6 is a predetermined amount, the liquid from the initial liquid level H to the discharge position S is discharged to leave a predetermined amount of liquid in the first container 10. be able to.

Then, the plug 16 of the first container 10 is
By discharging the chemical liquid remaining in the first container 10 from the vicinity of the inner wall surface 16a of the plug body 16 in the same manner as in the related art, such as another discharging tool or a syringe with the side down, a predetermined amount of the chemical liquid can be discharged. The liquid in the storage chamber 12 of the first container 10 can be divided and discharged. When drained in this way,
If a predetermined amount is set in advance, the discharge amount of the liquid for the first time or the next time can be adjusted, and therefore, the storage chamber 12 of the first container 10 can be adjusted without performing a special operation such as measurement.
The liquid in the inside can be easily divided and discharged equally or unequally. Even if the liquid in the first container 10 is divided and discharged, the amount of the total liquid discharged is the amount contained in the first container 10, and therefore, for example, the chemical liquid is divided into a plurality of times and the whole amount is administered. In such a case, if a predetermined amount is contained in the first container 10, the entire amount can be administered to the patient. In each of the above-described discharge operations, a predetermined amount can be discharged from the first container 10 without using another member.
6, it is possible to minimize the possibility of exposing the liquid and the discharging tool to the outside air, and easily discharge the liquid aseptically.

Next, an embodiment of the communication device of the present invention will be described with reference to the drawings. FIGS. 2A and 2B are cross-sectional views showing a liquid discharge state using the communication device of this embodiment.
The communication device 30 of this embodiment includes a plurality of discharge tools 1 for sequentially communicating the first container 10 and the plurality of second containers 20, and in this embodiment, a set of two discharge tools 1. is there. Here, the second container 20 is, for example, a soft container such as a resin bag, a hard container such as a vial bottle or another glass bottle, a syringe, or the like. In this embodiment, it is a flexible bag containing an infusion solution. This second
The container 20 is provided with an outlet 24, and this outlet 24
A communication part 26 as a part communicating with the first container 10 is provided at a position different from that of the first container 10. This contact site 26
Is sealed by a stopper 27 similar to that of the first container. The first container has the same configuration as that of the above embodiment, and is a vial here. In the first container, a drug solution to be mixed with the infusion solution in the second container 20 before administration is contained in a plurality of second containers, in this embodiment, in two containers. The discharge tools 1a and 1b have, on one end, a liquid discharge section 3 that communicates with the storage chamber 22 at a connection portion 26 of the second container 20, and a plug of the first container 10 on the other end. A hollow needle 7 having a piercing portion 5 through which the body 16 can be pierced is provided. The liquid discharge section 3 is capable of penetrating the plug 27 of the second container 20 and has a so-called double-ended needle shape. Further, the two discharge tools 1a and 1b have different lengths L from the restricting portion 9 to the piercing opening 6. Others are the same as the above embodiment. Further, the holder 32 that slidably holds the outer surface of the first container 10 is provided in the second container 20.
The discharge tools 1a and 1b are provided in the holder 32 between the plug 16 of the first container 10 and the second container 20 in the piercing direction. It is slidably housed. In the holder 32, the first container 10 is pressed toward the second container 20 and slid, so that the stopper 16 of the first container 10 and the stopper 27 of the second container 20 are respectively provided. The piercing portion 5 and the liquid discharging portion 3 are configured to be pierced.

In order to communicate the storage chamber 12 of the first container 10 with the storage chamber 22 of the second container 20 using such a communication device 30, the holder 32 is slid so that the hollow needle 7 to the storage chamber 2 of the second container 20.
2 and the piercing portion 5 is pierced through the plug 16 of the first container 10. And like the above embodiment,
The restricting portion 9 fixedly provided on the hollow needle 7 is
, The piercing opening 6 of the hollow needle 7 is disposed at the discharge position S1 in the storage chamber 12 of the first container 10 according to the length L from the regulating portion 9 to the piercing opening 6. . Thereby, the accommodation room 12 of the first container 10 and the second container 20
Of the hollow needle 7 is communicated with the storage chamber 22 of the hollow needle 7.

Using the communication device 30, the first container 10
In order to discharge the liquid in the second container 20 by dividing it into a plurality of second containers 20, first, a liquid having a long length L from the regulating portion 9 to the piercing opening 6 is used as the first container 10 as described above. And the second container 20 are communicated. After the communication, the second container 20 is placed below the first container 10 and the plug 16 of the first container 10 is placed.
Is placed in a discharge position S1 which is lower than the liquid level H of the storage chamber 12 of the first container 10 and is separated from the plug 16 which is a bottom portion in the use state when the container is in a state of use with the container facing downward. Is done. Then, in this state, the liquid in the storage chamber 12 of the first container 10 can be discharged by an internal pressure difference or gravity between the first container and the second container, and further by a pumping operation. At this time, the liquid corresponding to the volume from the liquid level H to the discharge position S1 is discharged to the second container 20 and mixed with the liquid in the second container 20. This amount of liquid is a necessary and sufficient amount to be mixed and used in another second container 20. At the same time, the remaining liquid can remain in the storage chamber 12 of the first container 10.

Next, the first container 10 and another second container 20 are communicated with each other by using a discharging tool 1b having a shorter length L from the discharging tool 1a to the piercing opening 6 from the regulating portion 9; Regulatory Department 9
Is brought into contact with the engaged portion 15, so that the piercing opening 6 is disposed at the discharge position S2 lower than the discharge position S1, and the first container 10 is stored in the storage chamber 22 of another second container 20. The liquid in the chamber 12 is discharged. At this time, since the liquid has been discharged by the discharger 1a, the liquid level of the liquid is D at the start. Then, when the liquid is discharged by the discharging tool 1b, the discharging tool 1b is placed in the second container 20 from the liquid level D.
The amount corresponding to the volume of the storage chamber 12 of the first container 10 up to the discharge position S2 is discharged to the second container 20. This amount of liquid is a necessary and sufficient amount to be mixed and used in another second container 20.

In this manner, the storage chamber 1 of the first container 10
When the two liquids are divided and discharged into the storage chambers of the plurality of second containers 20, the piercing openings 6 of the respective discharge tools 1a and 1b are disposed at different discharging positions S1 and S2 in the piercing direction, respectively. The accommodation room 1 of the first container 10 between the positions S1 and S2
Since the volume of the second container 2 is a predetermined amount, when discharging the liquid for the first time, the liquid of the amount corresponding to the volume of the first container 10 from the liquid level H to the discharge position S1 is discharged as in the above-described embodiment. The liquid can be discharged to the second container 20, and a predetermined amount of liquid corresponding to the volume of the storage chamber 12 of the first container 10 between the discharge positions S1 and S2 can be discharged to the second container 20. Therefore, it is possible to easily prevent microbial contamination and discharge a predetermined amount of the liquid in the first container 10 without performing operations such as weighing, etc., and to a different second container 20 depending on each discharge position. It can be distributed equally or unequally. In particular, the volume of the first container 10 from the liquid level H to the discharge position S1 and the first container 1 between the discharge positions S1 and S2
By setting the volume of the storage chamber 12 equal to 0, the first container can be easily divided equally.

In the above-described embodiment, as the plurality of discharge tools 1, a plurality of discharge tools having different lengths from the restricting portion 9 to the piercing opening 6 of the piercing portion 5 are combined as one set. However, when a so-called double-ended needle-shaped discharge tool is used, as shown in FIG. 3, common protruding portions 35 and 36 having openings 33 and 34 communicating with the communication passage 8 on both sides of the regulating portion 9 are used. The discharging tool 31 may be used. In this common ejector 31, one sharp projection 3
5 is longer and the other sharp projecting portion 36 is shorter, so that the length from the regulating portion 9 to the openings 33 and 34 is different. Therefore, when the first container and the second container are first communicated with each other, the sharp projecting portion 35 having the longer length L from the restricting portion 9 is used as the piercing portion, and the first container is used as described above. The first container 10 is communicated with the second container 20 by communicating the first container 10 with the second container 20.
Can be discharged to the second container 20. Next, in order to discharge the liquid remaining in the first container 10 to another second container 20, the common discharge tool 31 is inverted, and the sharp projection 34 on the shorter side of the length L from the regulating portion 9 is set. Is used as the piercing portion 5, and the accommodation chamber 12 of the first container 10 is
The liquid can be discharged from the first container 10 to the second container 20 by making the container communicate with the storage chamber 22 of the second container 20. At this time, the volume of the first container 10 corresponding to the difference in the length L between the sharp projections 34 and 35 is discharged. As described above, even when the common ejection tool 31 is used, the same effects as those of the ejection tool are obtained. The discharging device used for the first communication and the discharging device used for the next communication may be the same, but it is preferable to use different discharging devices in order to prevent microbial contamination. Further, in the above embodiment, two discharge tools are combined, but three or more discharge tools may be combined. In this case, the liquid can be divided and discharged into a large number of second containers.

To manufacture a discharge device having different lengths from the restricting portion 9 to the piercing opening 6 of the piercing portion 5 as in the above-mentioned embodiment, there is no particular limitation. You can do it. First, as shown in FIG. 4A, a hollow needle 7 having a communication passage 8 and having a discharge opening and a piercing opening communicated by the communication passage 8 is manufactured using a resin. At this time, preferably, step portions 9a having slightly different diameters from other portions are formed at a plurality of locations in the longitudinal direction of the outer surface of the hollow needle 7. The steps 9a have different distances to the adjacent ends of the hollow needles 7, respectively. In addition, as shown in FIG. 4B, separately from the hollow needle 7, a regulating portion forming member 9b having a through hole with a slit is manufactured. Then, if the hollow needle 7 is passed through the through hole of the regulating portion forming portion 9b, and is preferably fixed to the stepped portion 9a by engaging with an engaging method such as screwing, bonding, fitting, or the like, the regulating portion 9 is moved to the distal end portion. Dispensers with different lengths on both sides can be manufactured. At this time, by changing the engaging portion in the longitudinal direction of the hollow needle 7 to, for example, a different step portion 9a, the length from the restricting portion 9 of the obtained ejector 1 to the piercing opening 6 can be changed. In addition, it is possible to easily manufacture ejectors having different piercing portions using the same member. Although the length of the liquid discharge portion is different in inverse proportion to the length of the piercing portion, it is on the discharge side, and the position of the discharge opening is the second position.
The amount of liquid stored in the storage chamber of the container is large,
Since it is arranged in the liquid in the storage chamber of the second container, there is no particular problem.

Next, a communication device according to another embodiment is shown in FIG.
This will be described with reference to FIG. FIGS. 5A to 5C are cross-sectional views each showing a state where the first container and the second container are communicated with each other by using the ejector of this embodiment. This communication device 40
Basically has a discharge tool 41 having the same configuration as the discharge tool 31, but the distance from the regulating portion 9 to the piercing opening 6 is constant. The first container 10 and the second container 20 are the same as those in the above-described embodiment, but the illustration of the second container is omitted. The discharge tool 41 has a liquid discharge part 3 on one end side which communicates with the storage chamber 22 of the second container 20 and a piercing part which can pierce the stopper 16 of the first container 10 on the other end side. 5 and a discharge opening 4 and a piercing opening 6 communicating with the liquid discharging portion 3 and the piercing portion 5 by a communication passage 8.
, A restricting portion 9 fixed to the hollow needle 7, and an outer cylinder 42 connected to the restricting portion 9 and slidably disposed in a holder (not shown).
And a so-called double-ended needle shape. In addition, when the restricting portion 9 is locked to the locked portion 15, the communication device 40 causes the piercing opening 6 to move in a different discharging position S in the piercing direction.
Has a spacer 43 as a displacing means to be disposed at the position. The spacer 43 has, on one side, engaging means 44 for engaging the outside of the container opening 14 of the first container 10, and has, on the other side, a contact portion 45 for contacting the regulating portion 9. are doing. Note that the outer diameter of the contact portion 45 has the outer diameter of the container opening 14 of the first container 10 so that the outer cylinder 42 can move in the piercing direction until the contact portion 45 and the restricting portion 9 contact. A small diameter portion 46 having substantially the same diameter is formed. By mounting the spacer 43 near the top of the first container 10, the discharge position S1 can be displaced in the lower direction as compared to before the restricting portion 9 is mounted on the locked portion 15, and the discharge position S1 can be displaced. , S2, the volume of the storage chamber 12 of the first container 10 is a predetermined amount.

In order to divide the liquid in the first container 10 into a plurality of second containers 20 and discharge the liquid in the first container 10 using the communication device 40 having such a configuration, first, the spacer 43 is attached to the first container 10.
2 and the container 41 of the first container 10 and the second container 2 in the same manner as the discharge devices 1a and 1b of FIG.
0 is connected to the accommodation room 22. Then, after the communication, the second container 20 is arranged below the first container 10 and the plug 16 of the first container 10 is turned downward.
Discharge position S1 lower than the liquid level H of the storage chamber 12 of the container 10 of FIG.
Placed in In this state, due to the internal pressure difference or gravity between the first container 10 and the second container 20, and furthermore, a pumping operation or the like, it corresponds to the volume from the liquid level H in the storage chamber 12 of the first container 10 to the discharge position S1. The discharged liquid is discharged to the second container and can be mixed with the liquid in the second container 20. At the same time, the remaining liquid can remain in the storage chamber 12 of the first container 10. After the liquid is divided and discharged into one second container in this manner, the discharging tool 41 is removed from the plug 16 and the spacer 43 is attached to the first container 1.
0 and is fitted to the container opening 14. Next, the piercing portion 5 is pierced through the plug 16 of the first container 10 using the same or different discharging tool 41 as described above until the restricting portion 9 contacts the contact portion 45 of the spacer 41. Then, when the regulating portion 9 contacts the contact portion 45, the piercing opening 6 is disposed at a discharge position S2 different from the discharge position S1 in the storage chamber 12 of the first container 10. At this time, the liquid discharge part 4 is also pierced through the plug 27 of the second container (not shown). In this state, when the liquid remaining in the storage chamber 12 of the first container 10 is discharged to the second container 20 as described above, the volume of the storage chamber 1 corresponding to the difference between the discharge positions S1 and S2 is reduced. Only a corresponding predetermined amount of liquid can be drained into the second container. Therefore, the microorganisms can be easily prevented from being contaminated, and a predetermined amount of the liquid in the first container 10 can be transferred and distributed to the different second containers 20 without performing operations such as measurement. Moreover, since the displacement means is a spacer interposed between the locked portion and the restricting portion, the discharge position can be easily adjusted by adjusting one or a plurality of spacers, and the displacement is performed from the first container. Adjustment of the liquid amount is easy.

In this embodiment, the spacer 4
1 is provided with a cap 50 which can be attached and detached by a pull tab as shown in FIG. 5 (C). After the liquid in the first container 10 is discharged and the discharging tool 41 is removed, the spacer 4 is removed.
3 and the cap 50, so that the plug 1 can be inserted until the piercing portion 5 of the ejector 41 is pierced next time.
6 to prevent contamination by outside air. In particular, in this example, at the tip of the cap 50, for example, a sterilizing member 51 obtained by impregnating an elastically deformable member with a sterilizing agent is attached. The sterilizing member 51 is pressed against the outer surface to maintain a sterilized state. Therefore, the piercing portion 5 of the discharging tool 41 is next connected to the plug 1
6, since the outer surface of the plug 16 is not contaminated by microorganisms, the piercing portion 5 is contaminated by microorganisms and the liquid in the storage chamber 12 of the first container 10 is contaminated by microorganisms. Can be prevented. Therefore, microbial contamination does not easily occur even when the liquid contained in the first container 10 is divided and used a plurality of times. In this embodiment, an extension member 47 as a spacer having an extended contact portion 48 and a small diameter portion 49 as shown in FIG.
The small diameter portion 46 of the contact portion 45 can be fitted and mounted. According to the extension member 47, the position where the restricting portion 9 is restricted can be set to a position further away from the first container 10. This makes it possible to set the discharge positions of the piercing openings 6 where the restricting portions 9 are disposed in contact with the extended contact portions 48 in three or more stages.

FIG. 7 is a diagram showing an embodiment of the communication device according to still another aspect. In this embodiment, the first container 10
The container openings 14a and 14b are provided at one end and the other end, respectively, and the piercing portion 5 of the hollow needle 7 is sealed by pierceable plugs 16a and 16b. In addition, the discharging tool 61 has a first space between the hollow needle 7 and the outer cylinder 62.
The first restricting portion 63 that contacts and locks the locked portion 15a at one end of the container 10 and the second restricting portion that locks the locked portion 15b at the other end of the first container 10. A part 64 is provided. The first restricting portion 63 and the second restricting portion 64 are formed in a step shape. When the locked portion 15a at one end of the first container 10 comes into contact with the first restricting portion 63, the communication opening 6 of the hollow needle 7 closes the liquid chamber in the accommodation chamber 12 of the first container 10. The locked portion 15b at the other end of the first container 10 is disposed at the discharge position S1 lower than the surface H and separated from the plug 16a.
The first restricting portion 63 is arranged such that the communication opening 6 of the hollow needle 5 is disposed at the discharge position S2 near the bottom in the storage chamber 12 of the first container 10 when the abutment comes into contact with the second restricting portion 64. And a second regulating portion 64 are provided. According to such a communication device, when communicating the first container 10 and the second container 20, first, one end of the first container 10 is connected to the first restricting portion 63.
The hollow needle 7 is pierced through the plug 16a until it comes into contact with the second container 20 while the piercing opening 6 is disposed at the discharge position S1. When the liquid in the storage chamber 12 of the first container 10 is discharged into the second container 20 in this state, only the liquid from the liquid surface H to the discharge position S1 is discharged, and the rest is stored in the storage chamber 12. Can remain.

Next, in order to discharge the liquid into another second container 20, the first container 10 is turned over and the first container 1 is turned over.
The hollow needle 7 is pierced through the plug 16b until the locked portion 15b at the other end of the abutment 0 comes into contact with the second regulating portion 64, and the puncture opening 6 is formed.
Is disposed at the discharge position S2, and the liquid discharge unit 3 is connected to the next second container 20. In this state, if the liquid remaining in the storage chamber 12 of the first container 10 is discharged and transferred to the second container 20, the discharge positions S1, S
A predetermined amount of liquid corresponding to the volume of the storage chamber 12 corresponding to the difference between the two containers can be discharged to the second container 20, and the first containers 10 are stored in the plurality of second containers 20 as in the above-described embodiment.
Of liquid can be dispensed. According to such a container, since the displacement means is the plurality of pierceable plugs 16a and 16b that seal the plurality of openings 14a and 14b provided in the first container 10, the displacement means is divided. When discharging, different plugs can be used each time they are discharged, and if each plug is maintained in a sterile state until use,
Even if the hollow needle 7 is pierced and comes into contact with the stopper, the piercing portion 5 is not contaminated by microorganisms, and the liquid contained in the first container is contaminated via the piercing portion 5. Can be prevented.

Next, another embodiment of the communication device will be described. FIG. 8 is a cross-sectional view illustrating a state in which a discharge device of a communication device according to yet another embodiment is pierced into a first container.
Here, as in the above-described embodiment, the container opening 1 is provided at both ends.
A communication tool for applying to the first container 10 provided with 4a and 14b is provided. The discharging tool 61 used in this embodiment is the same discharging tool 61 as described above, but the outer cylinder 62 of the discharging tool 61 is provided with only one restricting portion 9 and the length of the piercing portion 5 is also reduced. It is constant. However, the container openings 14a and 14b have different lengths of the outer walls 67a and 67, respectively.
7b. Therefore, when the piercing portion 5 of the discharge tool 61 is made to enter the storage chamber 12 from the container opening portion 14a side until the regulating portion 9 contacts the engaged portion 15a, the piercing opening 6 of the piercing portion 5 is opened. It is located at a discharge position S1 lower than the liquid level H and separated from the plug 16a. In addition, container opening 1
When the piercing portion 5 of the ejection tool 61 is made to enter the accommodation room 12 from the 4b side until the regulating portion 9 contacts the engaged portion 15b,
The piercing opening 6 is disposed at the discharge position S2 at the bottom near the plug 16b. Therefore, even in such a container, the liquid in the storage chamber 12 of the first container 10 can be divided into a plurality of second containers and discharged in the same manner as described above. The effect is obtained.

The present invention is not limited to the above embodiments. For example, when a plurality of ejection tools having different lengths of piercing portions as shown in FIG.
Naturally, it is also possible to use a combination of the spacers as shown in the above, and it can be changed within the scope of the present invention.

[0030]

As described in detail above, according to the present invention, a liquid discharge portion is provided on one end side, and a piercing portion capable of piercing the plug of the first container is provided on the other end side, And a hollow needle having a discharge opening and a piercing opening communicating with the liquid discharging portion and the piercing portion through a communication passage, respectively, fixedly provided on the hollow needle, and locked in the piercing direction by the locked portion. A restricting portion for restricting the amount of the piercing portion penetrated into the plug of the first container, wherein the piercing opening is formed in the first container when the restricting portion is locked by the locked portion. Since the discharge device that is separated from the bottom when the container is discharged is used, a part of the liquid can be discharged from the first container aseptically and easily, and such a discharge device can be used. Is combined with other discharging means and displacement means, so that the liquid in the storage chamber of the first container can be divided easily and finely. It can be discharged to a plurality of the second container to prevent contamination by things.

[Brief description of the drawings]

FIGS. 1A and 1B are cross-sectional views illustrating a method for discharging a liquid by a discharge tool according to an embodiment of the present invention.

FIGS. 2A and 2B are cross-sectional views illustrating a communication state of the communication device according to the embodiment of the present invention.

FIG. 3 is a sectional view showing a common ejection tool used in the communication device according to the embodiment of the present invention.

FIGS. 4A to 4C are diagrams illustrating a method of manufacturing a discharge tool used in the communication device according to the embodiment of the present invention.

FIGS. 5A to 5C are cross-sectional views showing a communication state of the communication device according to the embodiment of the present invention.

FIG. 6 is a cross-sectional view of a spacer used in the communication device according to the embodiment of the present invention.

FIGS. 7A and 7B are cross-sectional views showing a communication state of the communication device according to the embodiment of the present invention.

FIGS. 8A and 8B are cross-sectional views illustrating a communication state of the communication device according to the embodiment of the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Discharge tool 3 Liquid discharge part 4 Discharge opening 5 Penetration part 6 Penetration opening 7 Hollow needle 8 Communication path 9 Restriction part 10 First container 12 Storage chamber 15 Engagement part 16 Plug

Claims (10)

[Claims] 1. A discharging device for storing a liquid and discharging the liquid from a storage chamber of a first container whose opening is closed by a pierceable plug, wherein the liquid is discharged to one end side. And a first end on the other end side.
A hollow needle having a piercing portion through which the stopper of the container can be pierced, and having a discharge opening and a piercing opening respectively connected to the liquid discharging portion and the piercing portion by a communication path; and fixed to the hollow needle. And a restricting portion that restricts the amount of the piercing portion penetrated into the plug of the first container by being locked to the locked portion in the piercing direction. The piercing opening is separated from the bottom portion of the first container at the time of discharge when locked by the locked portion,
In addition, the discharge tool is arranged at a discharge position where the volume of the storage chamber from the piercing opening to the bottom at the time of discharge is a predetermined amount. 2. The discharge device according to claim 1, wherein the discharge opening of the liquid discharge portion communicates with the storage chamber of the second container. 3. The liquid container according to claim 1, wherein the first container contains liquid to be discharged into a plurality of the second containers, and the predetermined amount is a liquid amount to be discharged into one of the second containers. 3. The discharging device according to 2. 4. The first container, which stores a liquid and communicates with the storage chamber of the first container and the storage chamber of the second container whose opening is closed by a pierceable plug. A communication device having a plurality of discharge tools for discharging the liquid to the second container, wherein the plurality of discharge tools have a liquid discharge portion communicating with the storage chamber of the second container on one end side. And a hollow needle having, at the other end, a piercing portion through which the plug of the first container can be pierced, and a discharge opening and a piercing opening respectively connected to the liquid discharging portion and the piercing portion by a communication passage. A restricting portion fixedly provided to the hollow needle and restricting the amount of piercing of the piercing portion into the stopper of the first container by being locked in the piercing direction by the locked portion; The restricting portions of the plurality of ejectors are locked in the locked portions, and the piercing openings are respectively pierced in the second container in the piercing direction. And at least one of the discharge positions is separated from the bottom of the first container at the time of discharge, and the volume of the storage chamber of the first container between the different discharge positions is a predetermined amount. A communication device, characterized in that: 5. The communication device according to claim 4, further comprising a displacement means for displacing the piercing opening in the piercing direction. 6. The first container, which stores a liquid and communicates with the storage chamber of the first container and the storage chamber of the second container whose opening is closed by a pierceable plug. A discharge device for discharging the liquid to the second container, comprising a liquid discharge portion communicating with a storage chamber of the second container on one end side and a first discharge portion on the other end side. A hollow needle having a piercing portion through which the stopper of the container can be pierced, and having a discharge opening and a piercing opening respectively connected to the liquid discharging portion and the piercing portion by a communication passage; And a restricting portion for restricting the amount of the piercing portion penetrated into the stopper of the first container by being locked in the piercing direction with the locked portion. When the restricting portion is locked to the locked portion, the piercing opening is arranged at a different discharging position in the piercing direction, Displacement means for separating at least one discharge position from the bottom portion of the first container at the time of discharge is provided, and the volume of the storage chamber of the first container between the different discharge positions is a predetermined amount. Communication device. 7. The first container contains a liquid to be discharged into a plurality of second containers, and the predetermined amount is one second container.
The communication device according to claim 4, 5 or 6, wherein the amount of the liquid to be discharged to the container is. 8. The communication device according to claim 6, wherein the displacement means includes a plurality of pierceable plugs for sealing a plurality of openings provided in the first container. 9. The communication device according to claim 6, wherein the displacement means includes a spacer interposed between the locked portion and the restricting portion. 10. The displacing means includes a plurality of locking positions different in a piercing direction of the hollow needle provided on one or more of the restricting portion, the locked portion, and the spacer. Item 10. The communication device according to any one of Items 6 to 9.