JP2001527572A5 - - Google Patents

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Publication number
JP2001527572A5
JP2001527572A5 JP1998550360A JP55036098A JP2001527572A5 JP 2001527572 A5 JP2001527572 A5 JP 2001527572A5 JP 1998550360 A JP1998550360 A JP 1998550360A JP 55036098 A JP55036098 A JP 55036098A JP 2001527572 A5 JP2001527572 A5 JP 2001527572A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998550360A
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English (en)
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JP2001527572A (ja
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Publication date
Priority claimed from US08/859,931 external-priority patent/US5945510A/en
Application filed filed Critical
Publication of JP2001527572A publication Critical patent/JP2001527572A/ja
Publication of JP2001527572A5 publication Critical patent/JP2001527572A5/ja
Ceased legal-status Critical Current

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Figure 2001527572
Figure 2001527572
Figure 2001527572
Figure 2001527572
Figure 2001527572
Figure 2001527572
Figure 2001527572
Figure 2001527572
Figure 2001527572
Figure 2001527572
Figure 2001527572
Figure 2001527572
JP55036098A 1997-05-21 1998-04-28 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子 Ceased JP2001527572A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/859,931 US5945510A (en) 1997-05-21 1997-05-21 Substantially pure zonulin, a physiological modulator of mammalian tight junctions
US08/859,931 1997-05-21
PCT/US1998/007636 WO1998052415A1 (en) 1997-05-21 1998-04-28 Substantially pure zonulin, a physiological modulator of mammalian tight junctions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2005130614A Division JP2005290008A (ja) 1997-05-21 2005-04-27 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子

Publications (2)

Publication Number Publication Date
JP2001527572A JP2001527572A (ja) 2001-12-25
JP2001527572A5 true JP2001527572A5 (ja) 2005-12-08

Family

ID=25332088

Family Applications (2)

Application Number Title Priority Date Filing Date
JP55036098A Ceased JP2001527572A (ja) 1997-05-21 1998-04-28 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子
JP2005130614A Withdrawn JP2005290008A (ja) 1997-05-21 2005-04-27 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2005130614A Withdrawn JP2005290008A (ja) 1997-05-21 2005-04-27 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子

Country Status (10)

Country Link
US (1) US5945510A (ja)
EP (1) EP0982988B1 (ja)
JP (2) JP2001527572A (ja)
AT (1) ATE250625T1 (ja)
AU (1) AU7249198A (ja)
CA (1) CA2290459A1 (ja)
DE (1) DE69818450T2 (ja)
DK (1) DK0982988T3 (ja)
ES (1) ES2209133T3 (ja)
WO (1) WO1998052415A1 (ja)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908825A (en) * 1997-01-09 1999-06-01 University Of Maryland At Baltimore Dosage composition for nasal delivery and method of use of the same
US6458925B1 (en) * 1998-08-03 2002-10-01 University Of Maryland, Baltimore Peptide antagonists of zonulin and methods for use of the same
US6733762B1 (en) 1998-09-14 2004-05-11 University Of Maryland, Baltimore Method of using Zot to inhibit lymphocyte proliferation in an antigen-specific manner
JP2002524531A (ja) * 1998-09-14 2002-08-06 ユニバーシティ・オブ・メリーランド, ボルティモア 抗原特異的様式でリンパ球増殖を阻害するための、Zotまたはゾヌリンを使用する方法
EP1221975B1 (en) 1999-10-04 2006-12-06 Nektar Therapeutics Al, Corporation Polymer stabilized neuropeptides
JP2003534287A (ja) * 2000-05-19 2003-11-18 ユニバーシティ・オブ・メリーランド, ボルティモア 糖尿病発症を予防または遅延させるためのゾヌリンのペプチドアンタゴニストの使用方法
US7034036B2 (en) * 2000-10-30 2006-04-25 Pain Therapeutics, Inc. Inhibitors of ABC drug transporters at the blood-brain barrier
EP1384469A1 (de) * 2002-07-25 2004-01-28 Cognis France S.A. Verfahren zum Schutz und zur Modulation von Tight Junctions
EP1384468A1 (de) * 2002-07-25 2004-01-28 Cognis France S.A. Verfahren zum Schutz und zur Modulation von Tight Junctions
EP1648917A4 (en) * 2003-07-15 2008-11-12 Univ Maryland AGONISTPOLYPEPTIDE OF THE RECEPTOR FOR ZOT AND ZONULIN
US20080038843A1 (en) * 2006-08-11 2008-02-14 University Of Maryland - Baltimore Method of diagnosing celiac disease
AR053661A1 (es) * 2005-01-14 2007-05-16 Univ Maryland Peptido para entregar vacunas via mucosas
AR057058A1 (es) * 2005-06-09 2007-11-14 Alba Therapeutics Corp Metodo para usar antagonistas de zonulina para prevenir la perdida o para regenerar celulas pancreaticas
CA2838399C (en) 2006-02-09 2017-03-07 Alba Therapeutics Corporation Formulations for a tight junction effector
US20070239520A1 (en) * 2006-03-31 2007-10-11 Devin Collins Motivational apparatus and method of motivation
US20090069247A1 (en) * 2006-10-06 2009-03-12 Blake Paterson Use of tight junction antagonists to treat inflammatory bowel disease
US8034776B2 (en) * 2006-10-26 2011-10-11 Alba Therapeutics Corporation Materials and methods for the treatment of celiac disease
US20100144646A1 (en) * 2006-11-03 2010-06-10 Blake Paterson Method of diagnosing and treating asthma
US8728491B2 (en) * 2007-05-07 2014-05-20 Alba Therapeutics Corporation Transcutaneous delivery of therapeutic agents
US20110201543A1 (en) * 2007-06-29 2011-08-18 Blake Paterson Use of tight junction antagonists in the treatment of acute lung injury and acute respiratory distress
US8198233B2 (en) 2007-07-26 2012-06-12 Alba Therapeutics Corporation Synthetic peptides that enhance tight junction permeability
CN104507309B (zh) 2012-03-19 2017-05-03 奇达拉治疗公司 用于棘白菌素类化合物的给药方案
WO2016190310A1 (ja) * 2015-05-26 2016-12-01 国立大学法人名古屋大学 タイトジャンクションの緩和剤、該緩和剤を含む薬剤吸収補助剤、及び該緩和剤を含む医薬組成物
CA3052975A1 (en) 2017-02-10 2018-08-16 Innovate Biopharmaceuticals, Inc. Compositions and methods for treating disease associated with permeability of intestinal epithelium
EP3755315A4 (en) 2018-02-23 2022-01-05 9 Meters Biopharma, Inc. COMPOUNDS AND METHODS OF TREATING THE PERMEABILITY OF SEALED CONNECTIONS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665389A (en) * 1995-05-24 1997-09-09 University Of Maryland At Baltimore Oral dosage composition for intestinal delivery and method of treating diabetes

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