JP2001527572A5 - - Google Patents
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- Publication number
- JP2001527572A5 JP2001527572A5 JP1998550360A JP55036098A JP2001527572A5 JP 2001527572 A5 JP2001527572 A5 JP 2001527572A5 JP 1998550360 A JP1998550360 A JP 1998550360A JP 55036098 A JP55036098 A JP 55036098A JP 2001527572 A5 JP2001527572 A5 JP 2001527572A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Description
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/859,931 US5945510A (en) | 1997-05-21 | 1997-05-21 | Substantially pure zonulin, a physiological modulator of mammalian tight junctions |
US08/859,931 | 1997-05-21 | ||
PCT/US1998/007636 WO1998052415A1 (en) | 1997-05-21 | 1998-04-28 | Substantially pure zonulin, a physiological modulator of mammalian tight junctions |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005130614A Division JP2005290008A (ja) | 1997-05-21 | 2005-04-27 | 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2001527572A JP2001527572A (ja) | 2001-12-25 |
JP2001527572A5 true JP2001527572A5 (ja) | 2005-12-08 |
Family
ID=25332088
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55036098A Ceased JP2001527572A (ja) | 1997-05-21 | 1998-04-28 | 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子 |
JP2005130614A Withdrawn JP2005290008A (ja) | 1997-05-21 | 2005-04-27 | 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005130614A Withdrawn JP2005290008A (ja) | 1997-05-21 | 2005-04-27 | 実質的に純粋なゾヌリン(zonulin)、哺乳動物密着結合の生理学的な調節因子 |
Country Status (10)
Country | Link |
---|---|
US (1) | US5945510A (ja) |
EP (1) | EP0982988B1 (ja) |
JP (2) | JP2001527572A (ja) |
AT (1) | ATE250625T1 (ja) |
AU (1) | AU7249198A (ja) |
CA (1) | CA2290459A1 (ja) |
DE (1) | DE69818450T2 (ja) |
DK (1) | DK0982988T3 (ja) |
ES (1) | ES2209133T3 (ja) |
WO (1) | WO1998052415A1 (ja) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5908825A (en) * | 1997-01-09 | 1999-06-01 | University Of Maryland At Baltimore | Dosage composition for nasal delivery and method of use of the same |
US6458925B1 (en) * | 1998-08-03 | 2002-10-01 | University Of Maryland, Baltimore | Peptide antagonists of zonulin and methods for use of the same |
US6733762B1 (en) | 1998-09-14 | 2004-05-11 | University Of Maryland, Baltimore | Method of using Zot to inhibit lymphocyte proliferation in an antigen-specific manner |
JP2002524531A (ja) * | 1998-09-14 | 2002-08-06 | ユニバーシティ・オブ・メリーランド, ボルティモア | 抗原特異的様式でリンパ球増殖を阻害するための、Zotまたはゾヌリンを使用する方法 |
EP1221975B1 (en) | 1999-10-04 | 2006-12-06 | Nektar Therapeutics Al, Corporation | Polymer stabilized neuropeptides |
JP2003534287A (ja) * | 2000-05-19 | 2003-11-18 | ユニバーシティ・オブ・メリーランド, ボルティモア | 糖尿病発症を予防または遅延させるためのゾヌリンのペプチドアンタゴニストの使用方法 |
US7034036B2 (en) * | 2000-10-30 | 2006-04-25 | Pain Therapeutics, Inc. | Inhibitors of ABC drug transporters at the blood-brain barrier |
EP1384469A1 (de) * | 2002-07-25 | 2004-01-28 | Cognis France S.A. | Verfahren zum Schutz und zur Modulation von Tight Junctions |
EP1384468A1 (de) * | 2002-07-25 | 2004-01-28 | Cognis France S.A. | Verfahren zum Schutz und zur Modulation von Tight Junctions |
EP1648917A4 (en) * | 2003-07-15 | 2008-11-12 | Univ Maryland | AGONISTPOLYPEPTIDE OF THE RECEPTOR FOR ZOT AND ZONULIN |
US20080038843A1 (en) * | 2006-08-11 | 2008-02-14 | University Of Maryland - Baltimore | Method of diagnosing celiac disease |
AR053661A1 (es) * | 2005-01-14 | 2007-05-16 | Univ Maryland | Peptido para entregar vacunas via mucosas |
AR057058A1 (es) * | 2005-06-09 | 2007-11-14 | Alba Therapeutics Corp | Metodo para usar antagonistas de zonulina para prevenir la perdida o para regenerar celulas pancreaticas |
CA2838399C (en) | 2006-02-09 | 2017-03-07 | Alba Therapeutics Corporation | Formulations for a tight junction effector |
US20070239520A1 (en) * | 2006-03-31 | 2007-10-11 | Devin Collins | Motivational apparatus and method of motivation |
US20090069247A1 (en) * | 2006-10-06 | 2009-03-12 | Blake Paterson | Use of tight junction antagonists to treat inflammatory bowel disease |
US8034776B2 (en) * | 2006-10-26 | 2011-10-11 | Alba Therapeutics Corporation | Materials and methods for the treatment of celiac disease |
US20100144646A1 (en) * | 2006-11-03 | 2010-06-10 | Blake Paterson | Method of diagnosing and treating asthma |
US8728491B2 (en) * | 2007-05-07 | 2014-05-20 | Alba Therapeutics Corporation | Transcutaneous delivery of therapeutic agents |
US20110201543A1 (en) * | 2007-06-29 | 2011-08-18 | Blake Paterson | Use of tight junction antagonists in the treatment of acute lung injury and acute respiratory distress |
US8198233B2 (en) | 2007-07-26 | 2012-06-12 | Alba Therapeutics Corporation | Synthetic peptides that enhance tight junction permeability |
CN104507309B (zh) | 2012-03-19 | 2017-05-03 | 奇达拉治疗公司 | 用于棘白菌素类化合物的给药方案 |
WO2016190310A1 (ja) * | 2015-05-26 | 2016-12-01 | 国立大学法人名古屋大学 | タイトジャンクションの緩和剤、該緩和剤を含む薬剤吸収補助剤、及び該緩和剤を含む医薬組成物 |
CA3052975A1 (en) | 2017-02-10 | 2018-08-16 | Innovate Biopharmaceuticals, Inc. | Compositions and methods for treating disease associated with permeability of intestinal epithelium |
EP3755315A4 (en) | 2018-02-23 | 2022-01-05 | 9 Meters Biopharma, Inc. | COMPOUNDS AND METHODS OF TREATING THE PERMEABILITY OF SEALED CONNECTIONS |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5665389A (en) * | 1995-05-24 | 1997-09-09 | University Of Maryland At Baltimore | Oral dosage composition for intestinal delivery and method of treating diabetes |
-
1997
- 1997-05-21 US US08/859,931 patent/US5945510A/en not_active Expired - Lifetime
-
1998
- 1998-04-28 EP EP98919778A patent/EP0982988B1/en not_active Expired - Lifetime
- 1998-04-28 AT AT98919778T patent/ATE250625T1/de not_active IP Right Cessation
- 1998-04-28 CA CA002290459A patent/CA2290459A1/en not_active Abandoned
- 1998-04-28 ES ES98919778T patent/ES2209133T3/es not_active Expired - Lifetime
- 1998-04-28 JP JP55036098A patent/JP2001527572A/ja not_active Ceased
- 1998-04-28 WO PCT/US1998/007636 patent/WO1998052415A1/en active IP Right Grant
- 1998-04-28 AU AU72491/98A patent/AU7249198A/en not_active Abandoned
- 1998-04-28 DK DK98919778T patent/DK0982988T3/da active
- 1998-04-28 DE DE69818450T patent/DE69818450T2/de not_active Expired - Lifetime
-
2005
- 2005-04-27 JP JP2005130614A patent/JP2005290008A/ja not_active Withdrawn