JP2001521489A5 - - Google Patents
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- Publication number
- JP2001521489A5 JP2001521489A5 JP1998513758A JP51375898A JP2001521489A5 JP 2001521489 A5 JP2001521489 A5 JP 2001521489A5 JP 1998513758 A JP1998513758 A JP 1998513758A JP 51375898 A JP51375898 A JP 51375898A JP 2001521489 A5 JP2001521489 A5 JP 2001521489A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71298996A | 1996-09-13 | 1996-09-13 | |
| US08/712,989 | 1996-09-13 | ||
| US87740097A | 1997-06-17 | 1997-06-17 | |
| US08/877,400 | 1997-06-17 | ||
| PCT/US1997/015899 WO1998011092A1 (en) | 1996-09-13 | 1997-09-11 | Tricyclic antitumor compounds being farnesyl protein transferase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001521489A JP2001521489A (ja) | 2001-11-06 |
| JP2001521489A5 true JP2001521489A5 (enExample) | 2005-05-12 |
Family
ID=27108923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51375898A Ceased JP2001521489A (ja) | 1996-09-13 | 1997-09-11 | ファルネシルタンパク質トランスフェラーゼインヒビターである三環式抗腫瘍性化合物 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0929544B1 (enExample) |
| JP (1) | JP2001521489A (enExample) |
| KR (1) | KR20000036111A (enExample) |
| CN (1) | CN1238770A (enExample) |
| AT (1) | ATE282036T1 (enExample) |
| AU (1) | AU4801197A (enExample) |
| CA (1) | CA2266015C (enExample) |
| DE (1) | DE69731544T2 (enExample) |
| ES (1) | ES2229340T3 (enExample) |
| HU (1) | HUP0001109A2 (enExample) |
| IL (1) | IL128931A0 (enExample) |
| WO (1) | WO1998011092A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5852034A (en) * | 1997-06-17 | 1998-12-22 | Schering Corporation | Benzo(5,6)cycloheptapyridine cyclic ureas and lactams useful as farnesyl protein transferase inhibitors |
| US6211193B1 (en) | 1997-06-17 | 2001-04-03 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| US5925639A (en) * | 1997-06-17 | 1999-07-20 | Schering Corporation | Keto amide derivatives useful as farnesyl protein transferase inhibitors |
| US6228865B1 (en) | 1997-06-17 | 2001-05-08 | Schering Corporation | Compounds useful for inhibition of farnesyl protein transferase |
| AU8253298A (en) * | 1997-06-17 | 1999-01-04 | Schering Corporation | Benzo(5,6)cyclohepta(1,2-b)pyridine derivatives useful for inhibition of farnesyl protein transferase |
| JP2002504143A (ja) * | 1997-06-17 | 2002-02-05 | シェーリング コーポレイション | ファルネシルタンパク質トランスフェラーゼの阻害に有用な化合物 |
| US6218401B1 (en) | 1997-06-17 | 2001-04-17 | Schering Corporation | Phenyl-substituted tricyclic inhibitors of farnesyl-protein transferase |
| AU2335699A (en) | 1998-01-21 | 1999-08-09 | Kyowa Hakko Kogyo Co. Ltd. | Chemokine receptor antagonists and methods of use therefor |
| US6613905B1 (en) | 1998-01-21 | 2003-09-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6509346B2 (en) | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| CN1289336A (zh) | 1998-01-21 | 2001-03-28 | 千禧药品公司 | 趋化因子受体拮抗剂和其使用方法 |
| DE69919720D1 (de) * | 1998-07-24 | 2004-09-30 | Russinsky Ltd | Verfahren zur herstellung von benzocycloheptapyridin-11-one |
| US6503926B2 (en) | 1998-09-04 | 2003-01-07 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6288083B1 (en) | 1998-09-04 | 2001-09-11 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7271176B2 (en) | 1998-09-04 | 2007-09-18 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use thereof |
| US6262216B1 (en) | 1998-10-13 | 2001-07-17 | Affymetrix, Inc. | Functionalized silicon compounds and methods for their synthesis and use |
| EP1296949A2 (en) | 2000-06-21 | 2003-04-02 | Bristol-Myers Squibb Pharma Company | Piperidine amides as modulators of chemokine receptor activity |
| US7342016B2 (en) | 2000-08-30 | 2008-03-11 | Schering Corporation | Farnesyl protein transferase inhibitors as antitumor agents |
| US7541365B2 (en) | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| DK1556358T3 (da) * | 2002-10-03 | 2007-09-10 | Schering Corp | Enantioselektiv alkylering af tricykliske forbindelser |
| TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
| CL2003002356A1 (es) * | 2002-11-18 | 2005-02-11 | Schering Corp | Compuestos derivados de 1-(1-acetil-piperidin-4-il)-(ester o amida)-4-(bencidrilo sustituido)-2-tert-butil-piperazina, composicion farmaceutica, y su uso en la inhibicion de 17b-hidroxiesteroide deshidrogenasa de tipo 3 y de enfermedades que dependen |
| WO2005017160A2 (en) | 2003-08-13 | 2005-02-24 | Children's Hospital Medical Center | Mobilization of hematopoietic cells |
| EP1695961A4 (en) * | 2003-12-17 | 2007-10-24 | Takeda Pharmaceutical | UREA DERIVATIVE, METHOD FOR THE PRODUCTION AND THEIR USE |
| WO2005089496A2 (en) * | 2004-03-18 | 2005-09-29 | The Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies |
| CN113549072B (zh) * | 2020-04-23 | 2024-12-06 | 鲁南制药集团股份有限公司 | 一种托法替布杂质ⅰ的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| JPH0676403B2 (ja) * | 1991-01-18 | 1994-09-28 | エスエス製薬株式会社 | 新規なベンゾ［５，６ シクロヘプタ［１，２−ｂ ピリジン誘導体及びこれを含有する抗アレルギー剤 |
| ATE210652T1 (de) * | 1993-10-15 | 2001-12-15 | Schering Corp | Tricyclische carbamat-derivate zur inhibierung der g-protein funktion und für die behandlung von proliferativen erkrankungen |
| US5721236A (en) * | 1993-10-15 | 1998-02-24 | Schering Corporation | Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| US5700806A (en) * | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| IL117798A (en) * | 1995-04-07 | 2001-11-25 | Schering Plough Corp | Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them |
| US5712280A (en) * | 1995-04-07 | 1998-01-27 | Schering Corporation | Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| MY119007A (en) * | 1995-12-22 | 2005-03-31 | Schering Corp | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases. |
-
1997
- 1997-09-11 KR KR1019997002134A patent/KR20000036111A/ko not_active Withdrawn
- 1997-09-11 CN CN97199602A patent/CN1238770A/zh active Pending
- 1997-09-11 JP JP51375898A patent/JP2001521489A/ja not_active Ceased
- 1997-09-11 DE DE69731544T patent/DE69731544T2/de not_active Expired - Fee Related
- 1997-09-11 AT AT97910710T patent/ATE282036T1/de not_active IP Right Cessation
- 1997-09-11 AU AU48011/97A patent/AU4801197A/en not_active Abandoned
- 1997-09-11 ES ES97910710T patent/ES2229340T3/es not_active Expired - Lifetime
- 1997-09-11 CA CA002266015A patent/CA2266015C/en not_active Expired - Fee Related
- 1997-09-11 EP EP97910710A patent/EP0929544B1/en not_active Expired - Lifetime
- 1997-09-11 WO PCT/US1997/015899 patent/WO1998011092A1/en not_active Ceased
- 1997-09-11 IL IL12893197A patent/IL128931A0/xx unknown
- 1997-09-11 HU HU0001109A patent/HUP0001109A2/hu unknown