JP2001520878A - エリスロポエチン媒介神経発生 - Google Patents
エリスロポエチン媒介神経発生Info
- Publication number
- JP2001520878A JP2001520878A JP2000518058A JP2000518058A JP2001520878A JP 2001520878 A JP2001520878 A JP 2001520878A JP 2000518058 A JP2000518058 A JP 2000518058A JP 2000518058 A JP2000518058 A JP 2000518058A JP 2001520878 A JP2001520878 A JP 2001520878A
- Authority
- JP
- Japan
- Prior art keywords
- cells
- neurons
- neural stem
- stem cells
- erythropoietin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/14—Erythropoietin [EPO]
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- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6304097P | 1997-10-24 | 1997-10-24 | |
| US60/063,040 | 1997-10-24 | ||
| PCT/CA1998/000991 WO1999021966A1 (en) | 1997-10-24 | 1998-10-23 | Erythropoietin-mediated neurogenesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001520878A true JP2001520878A (ja) | 2001-11-06 |
| JP2001520878A5 JP2001520878A5 (enExample) | 2006-01-05 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000518058A Pending JP2001520878A (ja) | 1997-10-24 | 1998-10-23 | エリスロポエチン媒介神経発生 |
Country Status (5)
| Country | Link |
|---|---|
| US (7) | US6165783A (enExample) |
| JP (1) | JP2001520878A (enExample) |
| AU (1) | AU9617398A (enExample) |
| CA (1) | CA2307017C (enExample) |
| WO (1) | WO1999021966A1 (enExample) |
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| US6165783A (en) * | 1997-10-24 | 2000-12-26 | Neuro Spheres Holdings Ltd. | Erythropoietin-mediated neurogenesis |
| US6610540B1 (en) * | 1998-11-18 | 2003-08-26 | California Institute Of Technology | Low oxygen culturing of central nervous system progenitor cells |
| DE19857609A1 (de) | 1998-12-14 | 2000-06-15 | Hannelore Ehrenreich | Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen |
| US7410941B1 (en) | 1999-04-13 | 2008-08-12 | The Kenneth S. Warren Institute, Inc. | Methods for treatment of neurodegenerative conditions by peripherally administered erythropoietin |
| US7345019B1 (en) * | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| DE19928210B4 (de) * | 1999-06-19 | 2005-08-18 | Neuroprogen Gmbh Leipzig | Neuronales Zellmaterial und Verfahren zu dessen Herstellung |
| AU784303B2 (en) | 1999-07-16 | 2006-03-09 | Prescient Neuropharma Inc. | Methods for producing and preparing cells for cell therapy |
| AU3499801A (en) * | 2000-02-11 | 2001-08-20 | Schepens Eye Res Inst | Isolation and transplantation of retinal stem cells |
| CN1318084C (zh) * | 2000-05-26 | 2007-05-30 | 奥索-麦克尼尔药品公司 | 神经保护肽 |
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| JP5053499B2 (ja) * | 2000-06-30 | 2012-10-17 | 地方独立行政法人東京都健康長寿医療センター | 脱髄疾患の予防及び治療薬 |
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| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| US7767643B2 (en) * | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| US6908902B2 (en) | 2001-02-02 | 2005-06-21 | Ortho-Mcneil Pharmaceutical, Inc. | Treatment of neurological dysfunction comprising fructopyranose sulfamates and erythropoietin |
| US7838292B1 (en) * | 2001-03-29 | 2010-11-23 | University Of Louisville Research Foundation, Inc. | Methods for obtaining adult human olfactory progenitor cells |
| AU2002325712C1 (en) * | 2001-08-30 | 2008-07-31 | Stem Cell Therapeutics Inc. | Differentiation of neural stem cells and therapeutic use theeof |
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| ATE541921T1 (de) * | 2001-09-14 | 2012-02-15 | Stem Cell Therapeutics Inc | Prolaktin-induzierte zunahme an neuronalen stammzellen und dessen therapeutische anwendung |
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| WO2003060085A2 (en) * | 2002-01-14 | 2003-07-24 | The Board Of Trustees Of The University Of Illinois | Mammalian neural stem cells, compositions and uses thereof |
| AU2003218045A1 (en) * | 2002-03-11 | 2003-09-29 | Ortho Mcneil Pharmaceutical, Inc | Methods for shp1 mediated neuroprotection |
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| EP1550715A1 (de) * | 2003-12-30 | 2005-07-06 | Bionethos Holding Gmbh | Verfahren zur Regenation von Gewebe |
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| CN101495078B (zh) * | 2006-02-08 | 2013-02-13 | Cvac系统有限公司 | 组合压力疗法 |
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| EP2785378B1 (en) | 2011-12-02 | 2020-05-13 | Armagen, Inc. | Methods and compositions for increasing arylsulfatase a activity in the cns |
| EP2814947B1 (en) | 2012-02-17 | 2018-11-21 | Schepens Eye Research Institute | Phenotype profile of human retinal progenitor cells |
| US10538589B2 (en) | 2015-01-14 | 2020-01-21 | Armagen Inc. | Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the CNS using a fusion antibody comprising an anti-human insulin receptor antibody and NAGLU |
| KR102056447B1 (ko) * | 2018-03-16 | 2019-12-16 | (주)메디노 | 신경줄기세포를 이용한 혈관형성 유도 방법 |
| CN110713982A (zh) * | 2019-11-25 | 2020-01-21 | 深圳科学之门生物工程有限公司 | 一种用于神经干细胞快速扩增的培养基 |
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| EP0594669B9 (en) * | 1991-07-08 | 2008-03-19 | NeuroSpheres Holdings Ltd. | Growth factor-responsive neural progenitor cells which can be proliferated in vitro. |
| US5750376A (en) * | 1991-07-08 | 1998-05-12 | Neurospheres Holdings Ltd. | In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny |
| ES2194016T5 (es) * | 1992-10-28 | 2007-11-16 | Neurospheres Holdings Ltd. | Factores biologicos y celulas germinales neurales. |
| US5700909A (en) * | 1993-07-30 | 1997-12-23 | The Regents Of The University Of California | Prosaposin and cytokine-derived peptides |
| CN1141058A (zh) * | 1993-11-09 | 1997-01-22 | 纽罗斯菲里斯控股有限公司 | 中枢神经系统干细胞的原位修饰和处理 |
| EP0792350A1 (en) * | 1994-11-14 | 1997-09-03 | Neurospheres Holdings Ltd. | Regulation of neural stem cell proliferation |
| US6165783A (en) * | 1997-10-24 | 2000-12-26 | Neuro Spheres Holdings Ltd. | Erythropoietin-mediated neurogenesis |
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| US6924142B2 (en) | 2005-08-02 |
| US20020094571A1 (en) | 2002-07-18 |
| US20050026136A1 (en) | 2005-02-03 |
| US20030104619A1 (en) | 2003-06-05 |
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