JP2001515060A5 - - Google Patents
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- Publication number
- JP2001515060A5 JP2001515060A5 JP2000509683A JP2000509683A JP2001515060A5 JP 2001515060 A5 JP2001515060 A5 JP 2001515060A5 JP 2000509683 A JP2000509683 A JP 2000509683A JP 2000509683 A JP2000509683 A JP 2000509683A JP 2001515060 A5 JP2001515060 A5 JP 2001515060A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- embedded image
- lipid
- lipids
- liposome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19735125 | 1997-08-13 | ||
| DE19834683A DE19834683A1 (de) | 1997-08-13 | 1998-07-31 | Neue Lipopolyamine, deren Darstellung und Anwendung |
| DE19834683.2 | 1998-07-31 | ||
| DE19735125.5 | 1998-07-31 | ||
| PCT/EP1998/005156 WO1999008997A1 (de) | 1997-08-13 | 1998-08-13 | Neue lipopolyamine, deren darstellung und anwendung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001515060A JP2001515060A (ja) | 2001-09-18 |
| JP2001515060A5 true JP2001515060A5 (https=) | 2010-05-06 |
| JP4504559B2 JP4504559B2 (ja) | 2010-07-14 |
Family
ID=26039111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000509683A Expired - Fee Related JP4504559B2 (ja) | 1997-08-13 | 1998-08-13 | 新リポポリアミン、その調製および適用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6281371B1 (https=) |
| EP (1) | EP1003711B1 (https=) |
| JP (1) | JP4504559B2 (https=) |
| AT (1) | ATE208369T1 (https=) |
| AU (1) | AU745958B2 (https=) |
| CA (1) | CA2299429C (https=) |
| ES (1) | ES2167939T3 (https=) |
| WO (1) | WO1999008997A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999052858A2 (en) * | 1998-04-08 | 1999-10-21 | Celltech Therapeutics Limited | Lipids |
| US6852334B1 (en) * | 1999-04-20 | 2005-02-08 | The University Of British Columbia | Cationic peg-lipids and methods of use |
| WO2000064858A1 (en) * | 1999-04-26 | 2000-11-02 | Celltech R&D Limited | Bipolar lipids and their use for the delivery of bioactive substances |
| WO2001043778A1 (en) * | 1999-12-17 | 2001-06-21 | Gene Therapy Systems, Inc. | Use of cationic lipids for intracellular protein delivery |
| US7189705B2 (en) | 2000-04-20 | 2007-03-13 | The University Of British Columbia | Methods of enhancing SPLP-mediated transfection using endosomal membrane destabilizers |
| US7294511B2 (en) * | 2001-03-22 | 2007-11-13 | Chromos Molecular Systems, Inc. | Methods for delivering nucleic acid molecules into cells and assessment thereof |
| US7001925B1 (en) | 2002-09-27 | 2006-02-21 | University Of Central Florida Research Foundation, Inc. | Compounds and method for enhancing the efficacy of anti-cancer drugs |
| US7906122B2 (en) * | 2003-06-18 | 2011-03-15 | Yissum Research Development Company Of The Hebrew University Of Jersusalem | Sphingoid polyalkylamine conjugates for Hepatitis B virus vaccination |
| EP1638919B1 (en) * | 2003-06-18 | 2012-09-26 | Biolab Ltd. | Sphingolipids polyalkylamines conjugates |
| US20110045001A1 (en) * | 2008-03-28 | 2011-02-24 | Biontex Laboratories Gmbh | Transfection results of non-viral gene delivery systems by influencing of the innate immune system |
| WO2013016058A1 (en) * | 2011-07-22 | 2013-01-31 | Merck Sharp & Dohme Corp. | Novel bis-nitrogen containing cationic lipids for oligonucleotide delivery |
| WO2016075154A1 (en) | 2014-11-10 | 2016-05-19 | Ethris Gmbh | Induction of osteogenesis by delivering bmp encoding rna |
| HUE065017T2 (hu) | 2019-02-14 | 2024-04-28 | Ethris Gmbh | Poliribonukleotid ciliogenezisre gyakorolt hatásának elemzése |
| WO2022096582A1 (en) | 2020-11-04 | 2022-05-12 | Ethris Gmbh | Use of ifn-lambda mrna for treating viral infections |
| WO2024121160A1 (en) | 2022-12-05 | 2024-06-13 | Ethris Gmbh | Regulator(s) of energy homeostasis-encoding rna molecule(s) with increased translation efficiency |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1963189A1 (de) | 1969-12-17 | 1971-06-24 | Bayer Ag | Verfahren zur Herstellung von flammfesten,Urethangruppen aufweisenden Schaumstoffen |
| US4339767A (en) | 1980-05-05 | 1982-07-13 | International Business Machines Corporation | High performance PNP and NPN transistor structure |
| CA2489769A1 (en) | 1989-03-21 | 1990-10-04 | Philip L. Felgner | Expression of exogenous polynucleotide sequences in a vertebrate |
| FR2645866B1 (fr) * | 1989-04-17 | 1991-07-05 | Centre Nat Rech Scient | Nouvelles lipopolyamines, leur preparation et leur emploi |
| US5538722A (en) | 1989-06-13 | 1996-07-23 | Stanford University | Isolation, growth, differentiation and genetic engineering of human muscle cells |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| IL103059A0 (en) | 1991-09-30 | 1993-02-21 | Boehringer Ingelheim Int | Conjugates for introducing nucleic acid into higher eucaryotic cells |
| DE4139001A1 (de) * | 1991-11-27 | 1993-06-03 | Boehringer Mannheim Gmbh | Verfahren zur einschleusung von nukleinsaeuren in zellen |
| US5972600A (en) | 1992-04-03 | 1999-10-26 | The Regents Of The University Of California | Separation of active complexes |
| US5334761A (en) * | 1992-08-28 | 1994-08-02 | Life Technologies, Inc. | Cationic lipids |
| GB9218762D0 (en) | 1992-09-04 | 1992-10-21 | Exxon Chemical Patents Inc | Esters |
| HUT73383A (en) | 1993-03-19 | 1996-07-29 | Boehringer Sohn Ingelheim | Process for preparing cancer vaccines |
| US5777153A (en) | 1994-07-08 | 1998-07-07 | Gilead Sciences, Inc. | Cationic lipids |
| US5939401A (en) | 1994-12-09 | 1999-08-17 | Genzyme Corporation | Cationic amphiphile compositions for intracellular delivery of therapeutic molecules |
| US5650096A (en) * | 1994-12-09 | 1997-07-22 | Genzyme Corporation | Cationic amphiphiles for intracellular delivery of therapeutic molecules |
| US6071890A (en) | 1994-12-09 | 2000-06-06 | Genzyme Corporation | Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy |
| WO1996040726A1 (en) | 1995-06-07 | 1996-12-19 | Genta Incorporated | Novel carbamate-based cationic lipids |
| AU707734B2 (en) | 1995-06-07 | 1999-07-15 | Regents Of The University Of California, The | Stabilization of polynucleotide complexes |
| US5811406A (en) | 1995-06-07 | 1998-09-22 | Regents Of The University Of California | Dry powder formulations of polynucleotide complexes |
| EP0840744A4 (en) | 1995-06-07 | 1999-03-10 | Genta Inc | CATIONIC LIPIDS BASED ON PHOSPHONIC ACID |
| DE19521412A1 (de) * | 1995-06-14 | 1996-12-19 | Boehringer Mannheim Gmbh | Neue kationische und polykationische Amphiphile, diese enthaltende Reagenzien und deren Verwendung |
| US6020526A (en) * | 1995-07-21 | 2000-02-01 | Genta, Incorporated | Amide-based cationic lipids |
| DE19607686A1 (de) | 1996-02-29 | 1997-09-04 | Chemicon Lab Gmbh | Neue metabolisierbare Lipopolyamine, deren Darstellung und Anwendung |
| US5747509A (en) | 1996-06-03 | 1998-05-05 | Schering Aktiengesellschaft | Method for lowering plasma levels of lipoprotein(a) |
-
1998
- 1998-08-13 CA CA2299429A patent/CA2299429C/en not_active Expired - Fee Related
- 1998-08-13 AT AT98946333T patent/ATE208369T1/de not_active IP Right Cessation
- 1998-08-13 EP EP98946333A patent/EP1003711B1/de not_active Expired - Lifetime
- 1998-08-13 WO PCT/EP1998/005156 patent/WO1999008997A1/de not_active Ceased
- 1998-08-13 ES ES98946333T patent/ES2167939T3/es not_active Expired - Lifetime
- 1998-08-13 JP JP2000509683A patent/JP4504559B2/ja not_active Expired - Fee Related
- 1998-08-13 AU AU93421/98A patent/AU745958B2/en not_active Ceased
- 1998-08-13 US US09/463,172 patent/US6281371B1/en not_active Expired - Lifetime
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