JP2001503413A5 - - Google Patents

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Publication number
JP2001503413A5
JP2001503413A5 JP1998520729A JP52072998A JP2001503413A5 JP 2001503413 A5 JP2001503413 A5 JP 2001503413A5 JP 1998520729 A JP1998520729 A JP 1998520729A JP 52072998 A JP52072998 A JP 52072998A JP 2001503413 A5 JP2001503413 A5 JP 2001503413A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP1998520729A
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English (en)
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JP2001503413A (ja
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Priority claimed from PCT/US1997/019648 external-priority patent/WO1998018476A1/en
Publication of JP2001503413A publication Critical patent/JP2001503413A/ja
Publication of JP2001503413A5 publication Critical patent/JP2001503413A5/ja
Withdrawn legal-status Critical Current

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Figure 2001503413
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Figure 2001503413
JP52072998A 1996-10-31 1997-10-29 不整脈を治療または予防する方法 Withdrawn JP2001503413A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2934996P 1996-10-31 1996-10-31
US60/029,349 1996-10-31
PCT/US1997/019648 WO1998018476A1 (en) 1996-10-31 1997-10-29 Methods of treating or preventing cardiac arrhythmia

Publications (2)

Publication Number Publication Date
JP2001503413A JP2001503413A (ja) 2001-03-13
JP2001503413A5 true JP2001503413A5 (ja) 2005-03-10

Family

ID=21848595

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52072998A Withdrawn JP2001503413A (ja) 1996-10-31 1997-10-29 不整脈を治療または予防する方法

Country Status (8)

Country Link
US (3) US5935945A (ja)
EP (1) EP0946183B1 (ja)
JP (1) JP2001503413A (ja)
AT (1) ATE361078T1 (ja)
AU (1) AU727391B2 (ja)
CA (1) CA2268922C (ja)
DE (1) DE69737689T2 (ja)
WO (1) WO1998018476A1 (ja)

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US5935945A (en) * 1996-10-31 1999-08-10 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia
TR200002796T2 (tr) * 1998-04-01 2000-12-21 Nortran Pharmaceuticals Inc. Aminosikloheksil eter bileşikleri ve bunların kullanımları.
US7507545B2 (en) 1999-03-31 2009-03-24 Cardiome Pharma Corp. Ion channel modulating activity method
US6531495B1 (en) 1999-10-02 2003-03-11 Aventis Pharma Deutschland Gmbh 2′-Substituted 1,1′-biphenyl-2-carboxamides, processes for their preparation, their use as medicaments, and pharmaceutical preparations comprising them
MY125533A (en) 1999-12-06 2006-08-30 Bristol Myers Squibb Co Heterocyclic dihydropyrimidine compounds
US7057053B2 (en) * 2000-10-06 2006-06-06 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7524879B2 (en) * 2000-10-06 2009-04-28 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
DE10059418A1 (de) 2000-11-30 2002-06-20 Aventis Pharma Gmbh Ortho, meta-substituierte Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
DE10060807A1 (de) 2000-12-07 2002-06-20 Aventis Pharma Gmbh Ortho, ortho-substituierte stickstoffhaltige Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
DE10061876A1 (de) 2000-12-12 2002-06-20 Aventis Pharma Gmbh Arylierte Furan- und Thiophencarbonsäureamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
DE10121003A1 (de) 2001-04-28 2002-12-19 Aventis Pharma Gmbh Anthranilsäureamide, Verfahren zur Herstellung, ihrer Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
US6783979B2 (en) 2001-06-06 2004-08-31 The Trustees Of Columbia University In The City Of New York Research Foundation Of State University Of New York Vectors encoding HCN channels and MiRP1
WO2002098287A2 (en) * 2001-06-06 2002-12-12 The Trustees Of Columbia University In The City Of New York A high throughput biological heart rate monitor that is molecularly determined
DE10128331A1 (de) 2001-06-12 2002-12-19 Aventis Pharma Gmbh Anthranilsäureamide mit Heteroarylsulfonyl-Seitenkette, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
US20090041841A1 (en) * 2003-05-02 2009-02-12 Cardiome Pharma Corp. Controlled release tablet formulations for the prevention of arrhythmias
SG167670A1 (en) * 2003-05-02 2011-01-28 Cardiome Pharma Corp Aminocyclohexyl ether compounds and uses thereof
US7345086B2 (en) 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
GB0315950D0 (en) 2003-06-11 2003-08-13 Xention Discovery Ltd Compounds
US7674820B2 (en) * 2003-08-07 2010-03-09 Cardiome Pharma Corp. Ion channel modulating activity I
US7345087B2 (en) * 2003-10-31 2008-03-18 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
DE102004009931A1 (de) * 2004-02-26 2005-09-15 Aventis Pharma Deutschland Gmbh Kv1.5-Blocker zur selektiven Steigerung der Vorhofkontraktilität und Behandlung der Herzinsuffizienz
CA2557085A1 (en) * 2004-02-26 2005-09-09 Merck & Co., Inc. Biological assay
US8058304B2 (en) * 2004-04-01 2011-11-15 Cardiome Pharma Corp. Merged ion channel modulating compounds and uses thereof
US7977373B2 (en) 2004-04-01 2011-07-12 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
US7772232B2 (en) 2004-04-15 2010-08-10 Bristol-Myers Squibb Company Quinazolinyl compounds as inhibitors of potassium channel function
GB0412986D0 (en) 2004-06-10 2004-07-14 Xention Discovery Ltd Compounds
ES2483940T3 (es) * 2004-11-08 2014-08-08 Cardiome Pharma Corp. Un nuevo régimen de dosificación para compuestos moduladores del canal iónico para el tratamiento de la fibrilación auricular aguda en un ser humano
US7576212B2 (en) 2004-12-09 2009-08-18 Xention Limited Thieno[2,3-B] pyridines as potassium channel inhibitors
US20060252830A1 (en) * 2005-05-06 2006-11-09 Brandon Stephen F Method for the treatment of magnesium and potassium deficiencies
US20060252831A1 (en) * 2005-05-06 2006-11-09 Christopher Offen Method for the treatment of magnesium and potassium deficiencies
GB0525164D0 (en) 2005-12-09 2006-01-18 Xention Discovery Ltd Compounds
GB0815782D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815781D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815784D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB201105659D0 (en) 2011-04-01 2011-05-18 Xention Ltd Compounds
NO3175985T3 (ja) 2011-07-01 2018-04-28
WO2013112932A1 (en) 2012-01-27 2013-08-01 Gilead Sciences, Inc. Combination therapies using late sodium ion channel blockers and potassium ion channel blockers
EP3206702A1 (en) * 2014-10-16 2017-08-23 Academisch Medisch Centrum Nk3 agonist for use in the treatment of a patient suffering from atrial arrhythmia or fibrillation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8412864D0 (en) * 1984-05-19 1984-06-27 Smith Kline French Lab Chemical compounds
GB8722776D0 (en) * 1987-09-28 1987-11-04 Smith Kline French Lab Chemical compounds
NZ234087A (en) * 1989-06-19 1991-08-27 Teikoku Hormone Mfg Co Ltd 2-(3-aryloxy(2-hydroxy-propylamino))-2-methylpropyl- aminophenyl pyridazine derivatives
US5428031A (en) * 1991-12-03 1995-06-27 Merck & Co., Inc. Methods of treating cardiac arrhythmia
HU214320B (hu) * 1991-12-20 1998-03-02 EGIS Gyógyszergyár Rt. Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására
US5506228A (en) * 1995-02-23 1996-04-09 Merck & Co., Inc. 2,6-diaryl pyridazinones with immunosuppressant activity
US5670504A (en) * 1995-02-23 1997-09-23 Merck & Co. Inc. 2,6-diaryl pyridazinones with immunosuppressant activity
US5935945A (en) * 1996-10-31 1999-08-10 Merck & Co., Inc. Methods of treating or preventing cardiac arrhythmia

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