JP2001500475A5 - - Google Patents

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Publication number
JP2001500475A5
JP2001500475A5 JP1998505472A JP50547298A JP2001500475A5 JP 2001500475 A5 JP2001500475 A5 JP 2001500475A5 JP 1998505472 A JP1998505472 A JP 1998505472A JP 50547298 A JP50547298 A JP 50547298A JP 2001500475 A5 JP2001500475 A5 JP 2001500475A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1998505472A
Other languages
English (en)
Japanese (ja)
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JP2001500475A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA1997/000489 external-priority patent/WO1998002452A2/en
Publication of JP2001500475A publication Critical patent/JP2001500475A/ja
Publication of JP2001500475A5 publication Critical patent/JP2001500475A5/ja
Pending legal-status Critical Current

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JP10505472A 1996-07-12 1997-07-11 細胞接着を調節するための化合物および方法 Pending JP2001500475A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2161296P 1996-07-12 1996-07-12
US60/021,612 1996-07-12
PCT/CA1997/000489 WO1998002452A2 (en) 1996-07-12 1997-07-11 Compounds and methods for modulating cell adhesion

Publications (2)

Publication Number Publication Date
JP2001500475A JP2001500475A (ja) 2001-01-16
JP2001500475A5 true JP2001500475A5 (https=) 2005-03-10

Family

ID=21805187

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10505472A Pending JP2001500475A (ja) 1996-07-12 1997-07-11 細胞接着を調節するための化合物および方法

Country Status (8)

Country Link
US (3) US6031072A (https=)
EP (1) EP0937103B1 (https=)
JP (1) JP2001500475A (https=)
AU (1) AU722985B2 (https=)
CA (1) CA2259966A1 (https=)
DE (1) DE69738326T2 (https=)
ES (1) ES2297861T3 (https=)
WO (1) WO1998002452A2 (https=)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465427B1 (en) 1996-07-12 2002-10-15 Mcgill University Compounds and methods for modulating cell adhesion
US7122623B2 (en) 1996-07-12 2006-10-17 Adherex Technologies, Inc. Compounds and methods for modulating cell adhesion
US6610821B1 (en) * 1996-07-12 2003-08-26 Mcgill University Compounds and methods for modulating endothelial cell adhesion
US20040006011A1 (en) * 1996-07-12 2004-01-08 Gour Barbara J. Peptidomimetic modulators of cell adhesion
US6207639B1 (en) * 1996-07-12 2001-03-27 Mcgill University Compounds and methods for modulating neurite outgrowth
US6169071B1 (en) * 1996-07-12 2001-01-02 Mcgill University Compounds and methods for modulating cell adhesion
US6417325B1 (en) * 1996-07-12 2002-07-09 Mcgill University Compounds and methods for cancer therapy
US20020168761A1 (en) 2000-01-24 2002-11-14 Gour Barbara J. Peptidomimetic modulators of cell adhesion
US6562786B1 (en) 1996-07-12 2003-05-13 Mcgill University Compounds and methods for modulating apoptosis
AU722985B2 (en) 1996-07-12 2000-08-17 Mcgill University Compounds and methods for modulating cell adhesion
US6333307B1 (en) * 1996-07-12 2001-12-25 Mcgill University Compounds and method for modulating neurite outgrowth
US6346512B1 (en) * 1996-07-12 2002-02-12 Mcgill University Compounds and methods for modulating cell adhesion
US6551994B1 (en) 1997-04-10 2003-04-22 Mcgill University Compounds and methods for inhibiting the interaction between α-catenin and β-catenin
US7481999B2 (en) 1998-05-05 2009-01-27 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin-mediated function
EP1075494A2 (en) 1998-05-05 2001-02-14 Adherex Technologies, Inc. Compounds and methods for modulating nonclassical cadherin-mediated functions
US20050203025A1 (en) * 1998-05-05 2005-09-15 Adherex Technologies, Inc. Compounds and methods for modulating nonclassical cadherin-mediated functions
US6472367B1 (en) 1998-05-05 2002-10-29 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin mediated cell adhesion
US6638911B1 (en) * 1998-05-05 2003-10-28 Adherex Technologies Inc. Compounds and methods for modulating desmosomal cadherin-mediated functions
US6680175B2 (en) 1998-05-05 2004-01-20 Adherex Technologies, Inc. Methods for diagnosing and evaluating cancer
EP1091762A1 (en) 1998-07-02 2001-04-18 Genzyme Corporation Transgene expression in polarized cells
US6277824B1 (en) 1998-07-10 2001-08-21 Adherex Technologies Compounds and methods for modulating adhesion molecule function
AU4417000A (en) * 1999-04-15 2000-11-02 Glaxo Group Limited Novel pharmaceutical composition suitable for gene therapy
US20040254099A1 (en) * 1999-04-21 2004-12-16 Adherex Technologies, Inc. Compounds and methods for modulating beta-catenin mediated gene expression
US6303576B1 (en) * 1999-04-21 2001-10-16 Adherex Technologies Inc. Compounds and methods for modulating β-catenin mediated gene expression
US6391855B1 (en) * 1999-06-02 2002-05-21 Adherex Technologies, Inc. Compounds and methods for modulating junctional adhesion molecule-mediated functions
US6787136B1 (en) 1999-09-03 2004-09-07 The Brigham And Women's Hospital, Inc. Methods and compositions for treatment of inflammatory disease using cadherin-11 modulating agents
AU2002226075A1 (en) * 2000-10-23 2002-05-06 University Of Kansas Cadherin peptides for drug delivery and inhibition of tumor metastasis/invasion
US6815426B2 (en) * 2001-02-16 2004-11-09 E. I. Du Pont De Nemours And Company Angiogenesis-inhibitory tripeptides, compositions and their methods of use
US20020192206A1 (en) * 2001-05-05 2002-12-19 Kozarov Emil V. Methods and compositions for angioproliferative disorder treatment
US20030105025A1 (en) * 2001-10-31 2003-06-05 Fortuna Haviv Tri-and tetrapeptides having antiangiogenic activity
US7175990B2 (en) * 2002-02-26 2007-02-13 The Regents Of The University Of California Method of determining endometrial receptivity
CA2504768A1 (en) * 2002-11-14 2004-05-27 Adherex Technologies, Inc. Compounds and methods for modulating functions of classical cadherins
AU2003298475A1 (en) * 2002-11-14 2004-06-18 Adherex Technologies, Inc. Compounds and methods for modulating desmosomal and atypical cadherin-mediated cell adhesion
US7196061B2 (en) 2003-09-10 2007-03-27 Wyeth Compounds that modulate neuronal growth and their uses
WO2005039506A2 (en) * 2003-10-24 2005-05-06 Exelixis, Inc. P70s6 kinase modulators and method of use
US20080139560A1 (en) * 2004-03-08 2008-06-12 Scion Pharmaceuticals, Inc. Ion Channel Modulators
US7169756B2 (en) * 2004-04-16 2007-01-30 Mcmaster University Streptogramin antibiotics
CA2763671A1 (en) * 2005-04-26 2006-11-02 Pfizer Inc. P-cadherin antibodies
CA2623565A1 (en) 2005-09-28 2007-04-05 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
US20110123535A1 (en) * 2006-05-15 2011-05-26 Biogen Idec Ma Inc. Use of Nogo Receptor-1 (NGR1) for Promoting Oligodendrocyte Survival
WO2008039525A2 (en) * 2006-09-27 2008-04-03 Adherex Technologies, Inc. Cadherin antagonists in combination with anticancer agents for use in cancer treatment
EP2997973A1 (en) 2006-11-15 2016-03-23 Dana-Farber Cancer Institute, Inc. Stabalized maml peptides and uses thereof
US20090291967A1 (en) * 2008-03-05 2009-11-26 Adherex Technologies, Inc. Small molecule modulators of cell adhesion
US9599603B2 (en) * 2008-07-16 2017-03-21 Case Western Reserve University Methods and compositions for modulating adhesion and migration of cadherin expressing cells
US9175047B2 (en) 2009-01-14 2015-11-03 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
US8680150B2 (en) 2009-05-28 2014-03-25 Ligand Pharmaceuticals, Inc. Small molecule hematopoietic growth factor mimetic compounds that activate hematopoietic growth factor receptors
CN102712675A (zh) * 2009-09-22 2012-10-03 爱勒让治疗公司 拟肽大环化合物
US8877188B2 (en) 2010-05-04 2014-11-04 The Brigham And Women's Hospital, Inc. Detection and treatment of non-dermal fibrosis
FR2980741B1 (fr) 2011-09-30 2014-03-14 Saint Gobain Procede d'assemblage par collage d'un vitrage sur un support avec interposition d'une cale d'ecartement, vitrage muni d'une cale d'ecartement, cale, cordon profile et ensemble de cales.
US8633158B1 (en) 2012-10-02 2014-01-21 Tarix Pharmaceuticals Ltd. Angiotensin in treating brain conditions
RU2015147241A (ru) 2013-05-24 2017-06-29 Терикс Фармасьютикалз Лтд. Пептиды ангиотензина при лечении синдрома марфана и связанных с ним нарушений
KR20160065969A (ko) 2013-10-11 2016-06-09 타릭스 파마슈티컬스 엘티디. 신규 펩티드 조성물
US9133241B2 (en) 2013-10-11 2015-09-15 Tarix Pharmaceuticals Ltd. Peptide compositions
EP3074417A4 (en) 2013-11-25 2017-05-03 Unm.Stc Cxcr antagonistic peptides and uses thereof
US9333233B2 (en) 2014-02-25 2016-05-10 Tarix Pharmaceuticals Ltd. Methods and compositions for the delayed treatment of stroke
WO2016001810A1 (en) 2014-07-01 2016-01-07 Pfizer Inc. Bispecific heterodimeric diabodies and uses thereof
US11097005B2 (en) 2014-12-15 2021-08-24 The Brigham And Women's Hospital, Inc. Use of cadherin-11 antagonists to treat metabolic disorders and/or increase insulin sensitivity
GB2538947A (en) * 2014-12-19 2016-12-07 Neuro-Bio Ltd Cancer
WO2016097753A1 (en) * 2014-12-19 2016-06-23 Neuro-Bio Ltd Cyclic acetylcholinesterase c-terminal peptide in the treatment or prevention of cancer or metastasis
US10059741B2 (en) 2015-07-01 2018-08-28 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
WO2017066552A1 (en) 2015-10-14 2017-04-20 Tarix Pharmaceuticals Ltd. Methods and compositions for the treatment of epidermolysis bullosa
KR102167755B1 (ko) * 2018-05-23 2020-10-19 주식회사 큐어바이오 단편화된 grs 폴리펩타이드, 이의 변이체 및 이들의 용도
JP2022544640A (ja) * 2019-06-21 2022-10-20 ユニバーシティ オブ カンザス 脳疾患の治療に有用な組成物および方法
WO2021183863A1 (en) 2020-03-13 2021-09-16 Constant Therapeutics Llc Methods and compositions for treatment of coronavirus infection
KR102911194B1 (ko) * 2020-11-05 2026-01-13 한국생명공학연구원 항염 및 조직 재생작용을 갖는 신규 펩타이드
CN116535406B (zh) * 2022-01-25 2025-06-24 中国科学院大连化学物理研究所 一种多萜衍生物的对映选择性合成方法及多萜衍生物
CN116535281B (zh) * 2022-01-25 2025-06-24 中国科学院大连化学物理研究所 一种手性环状单萜衍生物及其合成方法
WO2025122594A1 (en) 2023-12-04 2025-06-12 Constant Therapeutics, Llc Improved methods and compositions for the treatment of pemphigus or pemphigoid disease
WO2025137668A1 (en) 2023-12-21 2025-06-26 Constant Therapeutics, Llc Methods and compositions for the treatment of optic neuropathy

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079600A (en) * 1987-03-06 1992-01-07 Schnur Joel M High resolution patterning on solid substrates
JP2945680B2 (ja) * 1988-09-09 1999-09-06 旭硝子株式会社 ペプチド誘導体およびその用途
US5231082A (en) * 1989-05-10 1993-07-27 Monsanto Company Cyclic peptide with anti-metastasis activity
JPH05500504A (ja) * 1989-09-27 1993-02-04 アテナ・ニュウロサイエンスィズ・インコーポレイテッド 細胞付着阻止のための組成物及び使用方法
EP0619841B1 (en) * 1990-10-30 1998-07-08 La Jolla Cancer Research Foundation T-cadherin adhesion molecule
US5352667A (en) * 1991-11-22 1994-10-04 Ofer Lider Non-peptidic surrogates of the Arg-Gly-Asp sequence and pharmaceutical compositions comprising them
US5646250A (en) 1992-04-17 1997-07-08 Doheny Eye Institute Cadherin polypeptides
WO1994011401A1 (en) 1992-11-17 1994-05-26 Yale University Human homolog of the e-cadherin gene and methods based thereon
US5591432A (en) * 1993-02-17 1997-01-07 Becton, Dickinson And Company Antibody to the neural cell adhesion molecule and methods of use
US5665590A (en) * 1994-07-29 1997-09-09 Systemix, Inc. Method for isolating and directly cloning genes which encode cell-surface and secreted proteins
WO1996040781A1 (en) * 1995-06-07 1996-12-19 Tanabe Seiyaku Co., Ltd. CYCLIC PEPTIDE INHIBITORS OF β1 AND β2 INTEGRIN-MEDIATED ADHESION
GB9517098D0 (en) * 1995-08-21 1995-10-25 Imperial College Receptor
AU722985B2 (en) 1996-07-12 2000-08-17 Mcgill University Compounds and methods for modulating cell adhesion
US6169071B1 (en) 1996-07-12 2001-01-02 Mcgill University Compounds and methods for modulating cell adhesion
US6551994B1 (en) 1997-04-10 2003-04-22 Mcgill University Compounds and methods for inhibiting the interaction between α-catenin and β-catenin

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