JP2001321126A - Food composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a food composition for a diet allowing effectively losing the weight by a small intake. SOLUTION: This food composition for the diet is obtained by including an extract of a pericarp of Garcinia cambogia and citrus. Much effective diet effects can be expected than the cases of using each single composition by synergistic effects of the extract of the pericarp of Garcinia cambogia and the citrus in the composition.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a diet food composition.

[0002]

2. Description of the Related Art It is well known that obesity and overweight, which have been increasing in recent years, not only cause various diseases such as diabetes, but also cause great burdens and losses on social and economic aspects. However, dieting requires a significant change in the current lifestyle and involves difficulties. Therefore, low-calorie alternative foods, materials that inhibit fat absorption, suppress appetite, inhibit fat accumulation, and promote metabolism are desired. Although such preparations as pharmaceuticals exist, daily use in foods is prohibited by the Food Sanitation Law, and natural substances that can be used as foods instead of these pharmaceuticals are desired.

Hitherto, gymnema sylvester, which inhibits sugar absorption, chitosan, which inhibits lipid absorption, and Garcinia cambodia, which inhibits fat synthesis, have been known. Dietary supplements using these have also been known. I have. Garcinia cambodia, also known as malavar tamarind, which is known as a material that suppresses the production of fatty acids that cause obesity, contains (-)-hydroxycitric acid. This substance is a citric acid derivative, which inhibits the production of fatty acids by inhibiting ATP citrate lyase, which is an enzyme that converts citric acid generated from glucose into acetyl-CoA in the fatty acid synthesis pathway in the body. It has been shown to suppress accumulation.
At this time, the remaining glucose is accumulated as glycogen, so that it gives a feeling of fullness and alleviates the feeling of fatigue. Garcinia Cambodia is known as a kind of spice native to India, and is currently used as a diet material in many foods.

[0004] To decompose fat accumulated in adipose tissue, the sympathetic nerve is stimulated to induce noradrenaline,
It is necessary to stimulate the release of adrenaline and thereby stimulate adipose tissue. Amphetamine, ephedrine, and the like are known as substances that stimulate the sympathetic nerve, but they have high abuse properties, are rarely used, and are not suitable for use in foods. On the other hand, synephrine contained in citrus is a substance synthesized as a sympathomimetics in the 1930s, and it has been revealed that it is contained in citrus (The Journal of Biologic).
al Chemistry 239 3 930-932 1964) (Lloydia 3
Vol. 3, No. 2, pp. 244-254 1970). It is also known that these components stimulate mammalian adipocytes and promote lipolysis (C RAcad Sci III, Vol. 316, No. 5, pp. 519-523, 1993).

[0005]

The treatment and prevention of obesity requires various efforts such as dietary restriction and exercise.
It was hard to do. However, if it is possible to treat and prevent obesity without changing lifestyle by taking certain natural products at the same time, it will provide an effective means for treating and preventing obesity without considering the diet be able to. However, Garcinia Cambodia extract, which is used in many diet foods, is poorly soluble in water and has little effect by oral ingestion, so it consumes a large amount and the effective ingredient (-)-hydroxycitric acid is effective. It is difficult to ingest the amount, and it is desired to reduce the amount in terms of production cost. In recent years, a water-soluble Garcinia cambodia peel extract has been developed (Journal of the Japan Oil Chemists' Society Vol. 46 No. 12 1
467-28, 1997). However, although the Garcinia Cambodia peel extract alone consumes 2500 mg or more per day, the effect of weight loss is not sufficient.
On the other hand, when citrus fruits are used, the daily intake is 50 g or more in terms of dry weight, making it impossible to use them for foods.

[0006]

Means for Solving the Problems In order to solve these problems, the present inventor studied the enhancing effect of other substances on the diet effect of Garcinia Cambodia peel extract,
The present inventors have found that a diet effect is exhibited at a lower dose when used in combination with citrus fruits, and have accomplished the present invention. That is, the present invention is a diet food composition containing a Garcinia Cambodia peel extract and citrus fruits. More preferably, it is a diet food composition containing a water-soluble Garcinia cambodia peel extract and citrus fruits as active ingredients.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the present invention will be described in detail. The Garcinia Cambodia peel extract, which is a component used in the present invention, was extracted from Garcinia Cambodia peel with water or a solvent, etc., and was appropriately separated and concentrated if necessary. Things. As the solvent, water or a low-boiling organic solvent such as a lower alcohol, or a mixed solvent thereof can be used. After extraction with these solvents, if necessary, concentration, purification, sterilization, drying, etc. are performed as needed. Is done. The Garcinia Cambodia peel extract is preferably water-soluble. The water-soluble Garcinia cambodia peel extract is an extract that is completely dissolved in water and has an aqueous solution free from insoluble matter. In addition, the insoluble Garcinia cambodia peel extract is an extract that is not completely dissolved in water and insoluble matter is observed.

[0008] The other citrus fruits used in the present invention include daidai (Citrus Aurantium L.), unshiu mandarin (Citrus unshiu Marcov) and ponkan (Citrus reti).
culata Blanco), incense circle (Citrus wilsonii Tanaka),
Orange (Citrus sinensis Osbeck), Lemon (Citrus me
yeri Y. Tanaka), Cleopatra mandarin (Citrus re
shni Hort.), Kabuyao (Citrus macroptera Mon)
t.), Tahitium lime (Citruslatiforia Tanaka), Sweet lemon (Citrus limetta Risso), Kinukawa (Citr
us glaberrima Hort.ex Tanaka)
trus tangerina Hort.ex Tanaka), Hassaku (Citrus)
hassaku Hort.ex Tanaka), Sanpoukan (Citrus sul)
cate Hort.ex Takahashi), Covenimican (Citrus eryt)
hrosahiu Marcov), Citrus citrus (Citrus kinokuni H)
ort.ex Tanaka), Yatsushiro (Citrus yatsushiro Hort.ex)
Tanaka), Keraj (Citrus keraji Hort.ex Tanaka),
Tachibana (Citrus tachibana Tanaka), Sankitsu (Cit
rus sunki Hort.ex Tanaka), Shiikuwasha (Citrus)
deprssa Hayata), Koji (Citrus leiocarpa Hort.e)
xTanaka), Yuzu (Citrus junos Sieb.ex Tanaka), Bergamot (Citrus bergamia Risso et Poit), Iyokan (Citrus iyo Hort.ex Tanaka), Hyuganatsu (C
itrus tamurana Hort.ex Tanaka), Shunkokan (Ci
trus shunkokan Hort.ex Tanaka), Toukinkan (Citr
us madurensis Lour.), Sudachi (Citrus sudachi Hor)
t.ex Shirai), Kabos (Citrus sphaerocarpa Hort.ex)
Tanaka), Natsumikan (Citrus natsudaidai Hayata)
There is no particular limitation so long as it contains a sympathomimetics such as synephrine. Among these, a die is particularly preferable.

[0009] The citrus fruits of the present invention include mature or immature fruits, peels, seeds and the like of the above-mentioned citrus fruits.
Extracts extracted with leaves, petiole, branches, roots, flowers, etc., squeezed, dried powders or solvents, and separated or concentrated extracts or liquids or dried products are used. Preferably, the extract is extracted from fruits, peels, leaves or their raw, squeezed, dried powder or solvent, and particularly preferably is a liquid product or a dried product obtained by separating and concentrating these extracts. As the solvent in the case of extraction, a low-boiling organic solvent such as water or lower alcohol, or a mixed solvent thereof can be exemplified. After extraction with these solvents, if necessary, concentration, purification, sterilization, and drying are performed as appropriate. And used.

In the present invention, the amounts of the Garcinia Cambodia peel extract and the citrus fruits are calculated on a dry basis.
It is desirable that citrus fruits be contained in an amount of 0.1 to 2 parts by mass relative to 1 part by mass of the Garcinia Cambodia peel extract. If the amount of citrus is less than 0.1 part by mass, the desired effect of the present invention is not always sufficient, and if it exceeds 2 parts by mass, further improvement of the effect cannot be expected.

In the present invention, if necessary, a crude drug component,
Vitamins, stabilizers, preservatives, antioxidants, coloring agents, flavors, juices, sugars, starch, cellulose, cellulose derivatives, dextrins, and other excipients, adsorbents, and the like can be used as additives.

In order to produce a food composition of the present product, for example, in the case of tablets, the extract of Garcinia cambodia peel, citrus fruits and, if necessary, the above-mentioned additives are mixed,
Add a lubricant as needed to the dried and crushed one,
Tablet compression is sufficient. The food composition of the present invention can be used not only for tablets but also for any foods such as capsule foods, granular foods, general drinks, baked goods, breads and the like by a conventional method.
As shown in the following Examples and Comparative Examples, the food composition according to the present invention exerts a diet effect far more effectively than when Garcinia Cambodia peel extract and citrus are taken alone.

[0013]

The present invention will be described in detail with reference to the following examples, but the technical scope of the present invention is not limited thereto.

Examples 1, 2 and Comparative Examples 1-4 Garcinia cambodia used was obtained by separating, concentrating and drying an extract extracted from Garcinia cambodia peel with water. As the citrus, an extract extracted with a solvent from dried and shredded daidai was used. After mixing and granulating the raw materials according to the formulation shown in Table 1, the dried one was tableted to give a triangular tablet having a mass of 220 mg. Example 1 is a tablet containing a water-soluble Garcinia cambodia skin extract and citrus fruits, and Example 2 is a tablet containing an insoluble Garcinia cambodia skin extract and citrus fruits. Comparative Example 1 contains only the water-soluble Garcinia Cambodia peel extract, Comparative Example 2 contains only the insoluble Garcinia Cambodia peel extract, Comparative Example 3 contains only the citrus fruits, and Comparative Example 4 contains both the Garcinia Cambodia peel extract and the citrus fruits. It was not done.

The weight and body fat were evaluated as follows.
BMI of 25 or more (value obtained by dividing weight (kg) by the square of height (m). If this value is 25 or more, it is determined that the subject is obese) or 25% or more by body fat measurement by the impedance method ( For men and men who are 30% or more (female) who are obese, the tablets of Examples 1-2 and Comparative Examples 1-4 are divided into 15 tablets three times a day for 30 meals.
The test was carried out six minutes before the intake for 6 weeks (5 persons / group), and the body weight and body fat were measured.

[0016]

[Table 1]

[0017]

[Table 2]

As is clear from Table 2, in the groups using the test tablets of Examples 1 and 2 containing Garcinia Cambodia peel extract and citrus, the body weight and body fat were compared with those of Comparative Examples 1-4. It was confirmed that it was significantly reduced in comparison. Further, in the group using the test tablet of Example 1 containing a water-soluble Garcinia Cambodia peel extract and citrus fruits, body weight, body fat and other examples,
Compared with the group using the comparative example, it was confirmed that it was significantly reduced, and it was confirmed that there was a diet effect.

[0019]

Industrial Applicability The composition of the present invention contains a Garcinia Cambodia peel extract and citrus as active ingredients, more preferably a water-soluble Garcinia Cambodia peel extract and citrus as active ingredients, and comprises a Garcinia Cambodia peel Due to the synergistic effect of the extract and citrus, the purpose of the diet can be achieved much more effectively than when each is taken alone.

Continuing from the front page (72) Inventor Tomoko Tsuji 12-13, Eshinano, Totsuka-ku, Yokohama-shi, Kanagawa Prefecture Inside the FANCL Central Research Laboratory (72) Inventor Nobuyuki Matsushima 12-13, Eshinano, Totsuka-ku, Yokohama-shi, Kanagawa Prefecture F-term in FANCL Central Research Laboratory (reference) 4B018 MD52 ME01 MF01

Claims (4)

[Claims] 1. A diet food composition comprising a Garcinia Cambodia peel extract and citrus fruits. 2. The food composition according to claim 1, wherein the Garcinia Cambodia peel extract is water-soluble. 3. Citrus is a daisy (Citrus Aurantium)
L.), Citrus unshiu Marcov, Ponkan (Citrus reticulata Blanco), Incense Circle (Citrus w
ilsonii Tanaka), orange (Citrus sinensis Osbec)
k), Lemon (Citrus meyeri Y. Tanaka), Cleopatra mandarin (Citrus reshni Hort.), Kabuyao (Citru)
s macroptera Mont.), Tahitian lime (Citrus latifor)
ia Tanaka), Sweet Lemon (Citrus limetta Riss)
o), Kinukawa (Citrus glaberrimaHort.ex Tanaka),
Red citrus (Citrus tangerina Hort.ex Tanak
a), Hassaku (Citrus hassaku Hort.ex Tanaka), Sampoucan (Citrus sulcate Hort.ex Takahashi), Coverus mandarin (Citrus erythrosahiu Marcov), Kiss mandarin (Citrus kinokuni Hort.ex Tanaka), Yatsushiro (Cit)
rus yatsushiro Hort.exTanaka), Keraj (Citrus kera
ji Hort.ex Tanaka), Tachibana (Citrus tachibana Ta)
naka), Sanki (Citrus sunki Hort.ex Tanaka),
Shiikuwasha (Citrus deprssa Hayata), Koji (C
itrus leiocarpa Hort.ex Tanaka), Yuzu (Citrus jun
os Sieb.ex Tanaka), Bergamot (Citrus bergamia)
Risso etPoit), Iyokan (Citrus iyo Hort.ex Tana)
ka), Hyuganatsu (Citrus tamurana Hort.ex Tanak)
a), Citrus shunkokan Hort.ex Tanak
a), Kumquat (Citrus madurensis Lour.), Sudachi (Citrus sudachi Hort. exShirai), Kabos (Citrus)
sphaerocarpa Hort.ex Tanaka) and Natsumikan (Ci
trus natsudaidai Hayata), wherein the food composition is one or more fruits, peels, seeds, leaves, petiole, branches, roots, flowers or extracts thereof, and contains synephrine. . 4. The food composition according to claim 1, wherein the food composition contains 0.1 to 2 parts by mass of citrus fruits on a dry mass basis relative to 1 part by mass of the Garcinia Cambodia peel extract.