JP2001318095A5 - - Google Patents

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Publication number
JP2001318095A5
JP2001318095A5 JP2000135043A JP2000135043A JP2001318095A5 JP 2001318095 A5 JP2001318095 A5 JP 2001318095A5 JP 2000135043 A JP2000135043 A JP 2000135043A JP 2000135043 A JP2000135043 A JP 2000135043A JP 2001318095 A5 JP2001318095 A5 JP 2001318095A5
Authority
JP
Japan
Prior art keywords
opioid
disease
pruritus
measured
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000135043A
Other languages
English (en)
Other versions
JP4370683B2 (ja
JP2001318095A (ja
Filing date
Publication date
Application filed filed Critical
Priority to JP2000135043A priority Critical patent/JP4370683B2/ja
Priority claimed from JP2000135043A external-priority patent/JP4370683B2/ja
Priority to US09/704,319 priority patent/US6984493B1/en
Priority to CA002324982A priority patent/CA2324982A1/en
Publication of JP2001318095A publication Critical patent/JP2001318095A/ja
Publication of JP2001318095A5 publication Critical patent/JP2001318095A5/ja
Application granted granted Critical
Publication of JP4370683B2 publication Critical patent/JP4370683B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Description

【特許請求の範囲】
【請求項１】
血球、体液、または組織中の複数のオピオイドペプチド濃度を測定し、濃度比を求めるこ
とによってそう痒に対するオピオイドの関与を判定することを特徴とするそう痒疾患の検
査方法。
【請求項２】
測定するオピオイドペプチドがμオピオイドペプチドおよびκオピオイドペプチドである
請求項１記載の方法。
【請求項３】
測定するオピオイドペプチドがβエンドルフィンおよびダイノルフィンＡである請求項１
記載の方法。
【請求項４】
血球、体液、または組織中の複数のオピオイド受容体の発現程度を測定し、その発現程度
を比較することによってそう痒に対するオピオイドの関与を判定することを特徴とするそ
う痒疾患の検査方法。
【請求項５】
測定するオピオイド受容体がμオピオイド受容体およびκオピオイド受容体である請求項
４記載の方法。
【請求項６】
そう痒疾患が悪性腫瘍、糖尿病、肝疾患、腎不全、血液透析、腹膜透析、痛風、甲状腺
疾患、血液疾患、鉄欠乏、皮膚疾患、妊娠、寄生虫感染のいずれかに伴うそう痒である請
求項1から5のいずれかに記載の方法。
【請求項７】
そう痒疾患が薬剤性または心因性のそう痒である請求項1から5のいずれかに記載の方法
。
JP2000135043A 2000-05-08 2000-05-08 そう痒疾患の検査方法 Expired - Fee Related JP4370683B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2000135043A JP4370683B2 (ja) 2000-05-08 2000-05-08 そう痒疾患の検査方法
US09/704,319 US6984493B1 (en) 2000-05-08 2000-11-02 Method for examining the involvement of opioid peptides in prurtis
CA002324982A CA2324982A1 (en) 2000-05-08 2000-11-02 Method for examining disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000135043A JP4370683B2 (ja) 2000-05-08 2000-05-08 そう痒疾患の検査方法

Publications (3)

Publication Number Publication Date
JP2001318095A JP2001318095A (ja) 2001-11-16
JP2001318095A5 true JP2001318095A5 (ja) 2007-10-18
JP4370683B2 JP4370683B2 (ja) 2009-11-25

Family

ID=18643206

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000135043A Expired - Fee Related JP4370683B2 (ja) 2000-05-08 2000-05-08 そう痒疾患の検査方法

Country Status (3)

Country Link
US (1) US6984493B1 (ja)
JP (1) JP4370683B2 (ja)
CA (1) CA2324982A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200533355A (en) * 2004-03-30 2005-10-16 Toray Industries Antipruritic agent
KR101334401B1 (ko) 2006-04-11 2013-11-29 한국생명공학연구원 아토피 피부 질환의 기전을 모니터링 할 수 있는 아토피피부 질환의 진단 또는 치료용 마커 단백질
KR101257307B1 (ko) 2006-05-22 2013-04-23 한국생명공학연구원 인간 혈청 프로테옴에서 발굴한 아토피 피부 질환의 기전을모니터링 할 수 있는 아토피 피부 질환의 진단 또는치료용 마커 단백질
WO2011049433A1 (en) * 2009-10-23 2011-04-28 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Diagnosis and treatment of pruritis
US20140066475A1 (en) 2012-09-04 2014-03-06 Euro-Celtique S.A. Method For Treating Pruritus
US8637538B1 (en) 2012-12-14 2014-01-28 Trevi Therapeutics, Inc. Methods for treatment of pruritis
US20140179727A1 (en) 2012-12-14 2014-06-26 Trevi Therapeutics, Inc. Methods for treating pruritus
US8987289B2 (en) 2012-12-14 2015-03-24 Trevi Therapeutics, Inc. Methods for treating pruritus
KR20150003059A (ko) * 2013-06-28 2015-01-08 김종배 뇨 중 글리아돌핀(Gliadorphin) 농도 측정을 위한 면역분석법
CA3091752A1 (en) 2018-03-08 2019-09-12 Victoria Link Ltd Treatment of demyelinating diseases
SG11202100580UA (en) 2018-07-23 2021-02-25 Trevi Therapeutics Inc Treatment of chronic cough, breathlessness and dyspnea

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