JP2001281197A - Biosensor measuring apparatus - Google Patents

Biosensor measuring apparatus

Info

Publication number
JP2001281197A
JP2001281197A JP2000093178A JP2000093178A JP2001281197A JP 2001281197 A JP2001281197 A JP 2001281197A JP 2000093178 A JP2000093178 A JP 2000093178A JP 2000093178 A JP2000093178 A JP 2000093178A JP 2001281197 A JP2001281197 A JP 2001281197A
Authority
JP
Japan
Prior art keywords
sensor chip
measuring device
sensor
terminals
connection terminals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000093178A
Other languages
Japanese (ja)
Other versions
JP2001281197A5 (en
Inventor
Yoshinobu Tokuno
吉宣 徳野
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Panasonic Holdings Corp
Original Assignee
Matsushita Electric Industrial Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matsushita Electric Industrial Co Ltd filed Critical Matsushita Electric Industrial Co Ltd
Priority to JP2000093178A priority Critical patent/JP2001281197A/en
Priority to PCT/JP2001/002733 priority patent/WO2001073420A1/en
Publication of JP2001281197A publication Critical patent/JP2001281197A/en
Publication of JP2001281197A5 publication Critical patent/JP2001281197A5/ja
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/4875Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
    • G01N33/48771Coding of information, e.g. calibration data, lot number
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Food Science & Technology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

PROBLEM TO BE SOLVED: To automatically change the operation of a measuring instrument according to the difference of a reagent to be supported on a disposable sensor chip and the difference of calibration curve correction for correcting an output value obtained, relating to the electrochemical measurement of a component in a liquid sample such as blood by attaching a disposable the sensor chip to the measuring instrument. SOLUTION: The sensor chip 1 has electrode terminals 5 and 6 formed in different positions depending on the difference of a calibration curve correcting method due to the differences of a reagent to be carried and a manufacturing lot. The measuring instrument 2 has connecting terminals 8, 9, 10 and 11 formed to correspond to the plural kinds of electrode forming positions of the sensor chip 1. The measuring instrument 2 identifies the kind of the sensor chip by changing switches 12, 13, 14 and 15 in sequence, and determining which of the connecting terminals will conduct.

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【発明の属する技術分野】本発明は、液体試料をセンサ
チップに採取して測定器に接続し、その特定成分の濃度
など電気化学的に測定しうるバイオセンサ測定装置に関
するものである。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a biosensor measuring device which collects a liquid sample on a sensor chip, connects it to a measuring instrument, and electrochemically measures the concentration of a specific component.

【従来の技術】従来のバイオセンサ測定装置として、人
体からごく微量の血液等の体液を、使い捨てのセンサチ
ップ内に採取して、このセンサチップに担持した特定の
試薬との反応により生じる電流値を、センサチップを接
続した測定器で読み取り、血糖、コレステロール、乳酸
などの値を測定するものがある。このような使い捨ての
センサチップは、体液を採取するためのケーシング、電
極および試薬から構成されるが、センサチップに担持す
る試薬以外の部分は共用することが可能である。また測
定器においても、本質的には、検出した電流値を各濃度
に対応する値に変換する算出式を変えれば、ハードウエ
アの部分は共用することができる。しかしながら共用す
る場合には、例えば、血糖測定用のセンサチップを、コ
レステロール測定用の測定器に接続すると、正常な測定
動作を行うことができない問題があるため、従来は、セ
ンサチップの外形形状や、測定器の接続部の形状を変え
ることにより、異種のセンサチップと測定器との誤接続
を防止していた。また、センサチップ上に試薬を形成す
る製造工程において、各ロット毎の性能のばらつきを避
けることができないため、測定器では、実際に検出した
電流値に対して、この製造時のばらつきを補正して、血
糖値やコレステロール値などを表示することが必要であ
る。このため従来は、測定器にセンサチップの出力値の
ばらつきを補正するための検量線補正式を設定してお
き、また、センサチップには各ロット毎に検量線補正式
の切換用チップを付属させていた。そして使用者は、測
定に先だって切換用チップを測定器にセットして、セン
サチップに合った検量線補正式の設定を行い測定を行っ
ていた。
2. Description of the Related Art As a conventional biosensor measuring device, a very small amount of body fluid such as blood is collected from a human body into a disposable sensor chip, and a current value generated by a reaction with a specific reagent carried on the sensor chip is measured. Is read by a measuring device to which a sensor chip is connected, and the values of blood sugar, cholesterol, lactic acid, and the like are measured. Such a disposable sensor chip is composed of a casing for collecting body fluid, an electrode and a reagent, but portions other than the reagent carried on the sensor chip can be shared. Also, in the measuring instrument, the hardware can be used in common if the calculation formula for converting the detected current value into a value corresponding to each concentration is changed. However, in the case of common use, for example, when a sensor chip for measuring blood glucose is connected to a measuring device for measuring cholesterol, there is a problem that a normal measuring operation cannot be performed. In addition, by changing the shape of the connecting portion of the measuring device, erroneous connection between different types of sensor chips and the measuring device has been prevented. Also, in the manufacturing process of forming the reagent on the sensor chip, it is inevitable that the performance of each lot varies, so the measuring instrument corrects this variation in the manufacturing for the actually detected current value. It is necessary to display blood sugar level, cholesterol level and the like. For this reason, conventionally, a calibration curve correction formula for compensating for variations in the output values of the sensor chip has been set in the measuring instrument, and a switch for calibration curve correction formula switching is attached to each sensor chip. I was letting it. Prior to the measurement, the user sets the switching chip in the measuring instrument, sets the calibration curve correction formula suitable for the sensor chip, and performs the measurement.

【発明が解決しようとする課題】上記従来の構成で示し
たもののうち、試薬以外の部分を共用する場合において
は、各測定目的に応じて、センサチップの外形形状や、
測定器の接続部の形状を変えているため、各目的毎に金
型をはじめ生産設備の変更を余儀なくされており、コス
ト高となるため、共用化が充分に図れてはいなかった。
また検量線の補正を行うものについては、ユーザーが切
換用チップを用いて設定する必要があり、目の不自由な
人や老人、子どもには操作が困難で煩わしかったり、ま
た、検量線の切り換えの設定を忘れたときには正確な値
が表示されなかったりするという問題があった。
In the above-described conventional configuration, when a portion other than the reagent is used in common, the outer shape of the sensor chip and the outer shape of the sensor chip are determined in accordance with each measurement purpose.
Since the shape of the connecting portion of the measuring instrument was changed, the production equipment including the mold had to be changed for each purpose, and the cost was high, so that the common use was not sufficiently achieved.
In addition, the calibration curve correction must be set by the user using the switching chip, and it is difficult and troublesome for visually impaired people, the elderly, and children. If the user forgets to change the setting, there is a problem that an accurate value is not displayed.

【課題を解決するための手段】そこで上記課題を解決す
るために、本発明のバイオセンサ測定装置は、試薬や検
量線補正式等の種別の違いに応じて、センサチップに形
成する一対の電極端子を互いに異なる位置に形成したも
のであり、測定器については、複数種のセンサチップの
電極端子位置に対応して、それぞれ接続端子を備えてお
り、センサチップが測定器に装着されたときに、電極端
子との導通が得られる接続端子がいずれの接続端子かを
検出することにより、センサチップの種別を判別し、動
作条件の制御や、検量線の補正式を切換ることを特徴と
したものである。
In order to solve the above-mentioned problems, a biosensor measuring apparatus according to the present invention comprises a pair of electrodes formed on a sensor chip in accordance with the type of reagent or calibration curve correction type. The terminals are formed at positions different from each other, and the measuring device has connection terminals corresponding to the electrode terminal positions of a plurality of types of sensor chips, respectively, when the sensor chip is mounted on the measuring device. By detecting which connection terminal is a connection terminal that can be electrically connected to the electrode terminal, the type of the sensor chip is determined, the operating condition is controlled, and the correction equation of the calibration curve is switched. Things.

【発明の実施の形態】(実施の形態1)以下に、本発明
の一実施の形態について、図1及び図2を参照して説明
する。図1は、本実施の形態におけるバイオセンサ測定
装置を示す概略図であり、測定器については、センサチ
ップとの接続部分の構成のみを模式的に表している。図
1において、1は液体試料を添加するためのセンサチッ
プであり、2はセンサチップが装着される測定器2のう
ち接続部を拡大して示している。センサチップ1は、ポ
リエチレン樹脂等のシートをプレス打抜き等で得られる
基材3上に、添加された液体試料と反応する酵素試薬4
と、酵素反応によって作用電極と対電極とで得られる反
応電流を、測定器2により検出するための電極端子5,
6を形成している。測定器2の接続部は、センサチップ
の外形と係合するよう樹脂成形されたコネクタ7には、
4つの接続端子8,9,10,11を形成しており、セ
ンサチップ1の電極端子5に対して、接続端子8,9の
いずれか一方が、電極端子6に対しては接続端子10,
11のいずれか一方が接続するよう構成している。1
2,13,14,15はスイッチであり、スイッチを接
続することにより、図示しない測定器2内部の電気回路
に接続された信号線16,17と接続端子8,9,1
0,11とを選択的に接続可能にしている。スイッチを
接続する組合せは、スイッチ12とスイッチ15、スイ
ッチ12とスイッチ14、スイッチ13とスイッチ1
5、スイッチ13とスイッチ14の組み合わせで、その
組み合わせのスイッチのみを閉じるよう順次切り換えを
行う。センサチップ1は、具体的に図2に示すように、
外形が全く同じではあるものの、試薬または、製造ロッ
トの相違によって、電極端子5,6を異なる位置に形成
した(a)、(b)、(c)、(d)の4つの種類があ
る。すなわち、試薬を異なるものにする場合は、(a)
は血糖用、(b)はコレステロール用、(c)は乳酸
用、(c)は尿酸用という具合にする。また製造ロット
の相違に伴う検量線補正式については、電極端子位置と
適用する検量線補正式とを対応させている。このような
センサチップ1を測定器2に装着したときには、測定器
2は、直ちにスイッチ12,13,14,15を下記の
ように順次切り換えて、電極端子5,6との導通の得ら
れる接続端子を検出する。まずはスイッチ13とスイッ
チ14のみを閉じ、応答が得られると、センサチップ1
は図2の(a)と特定できる。応答が得られない場合
は、スイッチ13とスイッチ15のみを閉じる。このと
き応答が得られれば、センサチップは図2の(b)と特
定できる。これでも応答がえられない場合は、スイッチ
12とスイッチ14のみを閉じ、応答が得られればセン
サチップは図2の(c)と特定できる。上記の動作で応
答が得られなければ、最後にスイッチ12とスイッチ1
5を閉じ、導通を検出することにより、センサチップは
図2の(d)と特定できる。なお、測定器2のスイッチ
を切り換える動作は、センサチップ1の4つの種類に対
応した全ての切り換え動作を行う必要はなく、導通する
電極端子を検出できた時点で切り換え動作を終えること
ができる。以上により、センサの種別が特定できること
となり、測定器は、センサチップに担持された試薬に応
じた測定や、得られる測定値に対して検量線補正の設定
等を自動で行うことになる。なお上記の例では、測定器
2に、2対の接続端子を設けたが、それ以上増やすこと
も可能である。N対(Nは2以上の整数)とした場合
は、2N種類のセンサチップを判別することができるこ
ととなる。 (実施の形態2)以下に、本発明の実施の形態2につい
て、図3、4を参照して説明する。図3において、21
は液体試料を添加するためのセンサチップであり、22
はセンサチップが装着される測定器22のうち装着部を
拡大して示している。センサチップ21は、ポリエチレ
ン樹脂等のシートをプレス打抜き等で得られる基材23
上に、添加された液体試料と反応する試薬24と、試薬
との反応で得られる反応電流を検出するための電極端子
25,26をそれぞれ形成している。センサチップ21
は、具体的に図4に示すように、外形が全く同じではあ
るものの、試薬または、製造ロットの相違に伴う検量線
補正式の違いによって(a)、(b)、(c)の3つの
種類がある。上述の実施の形態1と異なるところは、セ
ンサチップの一対の電極端子のうち、一方の電極端子2
5を同じ位置に形成したことと、測定器22の接続端子
についても、電極端子25に対応する端子を共通の接続
端子28とし、他方の3つの接続端子29,30,31
を順次切り換えるようにしたことである。測定器22の
装着部は、センサチップの外形と係合するよう樹脂成形
されたコネクタ27に、センサチップ21の電極端子2
5,26と接続可能なように、4つの接続端子28,2
9,30,31を形成している。32,33,34はス
イッチであり、スイッチを接続することにより、図示し
ない測定器22内部の電気回路に接続された信号線37
と接続端子29,30,31とを選択的に接続可能にし
ている。ここで例えば、センサチップ21を測定器22
に接続し、スイッチの順次切り換えを行う。スイッチ3
2を接続したとき応答が得られた場合、センサチップは
図4の(a)と特定できる。スイッチ33を接続したと
き応答が得られた場合、センサチップは図4の(b)と
特定できる。スイッチ34を接続したとき応答が得られ
た場合、センサチップは図4の(c)と特定できる。こ
の例の場合も、センサチップの電極端子と導通する接続
端子を検出できた時点で、スイッチの切り換え動作を終
えることができる。また、共通としない、他方の接続端
子の数Nだけ、センサの種別を判別することができる。
以上により、センサの種別が特定できることとなり、測
定器は、センサチップに担持された試薬に応じた測定
や、得られる測定値に対して検量線補正の設定等を自動
で行うことになる。
(Embodiment 1) An embodiment of the present invention will be described below with reference to FIGS. FIG. 1 is a schematic diagram illustrating a biosensor measurement device according to the present embodiment, and the measurement device schematically illustrates only a configuration of a connection portion with a sensor chip. In FIG. 1, reference numeral 1 denotes a sensor chip for adding a liquid sample, and reference numeral 2 denotes an enlarged connection portion of a measuring device 2 to which the sensor chip is attached. The sensor chip 1 has an enzyme reagent 4 that reacts with a liquid sample added on a base material 3 obtained by stamping a sheet of polyethylene resin or the like.
And an electrode terminal 5 for detecting a reaction current obtained between the working electrode and the counter electrode by the enzymatic reaction with the measuring device 2.
6 are formed. The connecting portion of the measuring device 2 has a connector 7 which is resin-molded so as to engage with the outer shape of the sensor chip.
Four connection terminals 8, 9, 10, 11 are formed. One of the connection terminals 8, 9 is provided for the electrode terminal 5 of the sensor chip 1, and the connection terminals 10, 9 are provided for the electrode terminal 6.
11 are connected. 1
Reference numerals 2, 13, 14, and 15 denote switches. By connecting the switches, signal lines 16, 17 connected to an electric circuit inside the measuring instrument 2 (not shown) and connection terminals 8, 9, 1 are connected.
0 and 11 can be selectively connected. The combinations for connecting the switches are: switch 12 and switch 15, switch 12 and switch 14, switch 13 and switch 1
5. The combination of the switch 13 and the switch 14 is sequentially switched so that only the switch of the combination is closed. The sensor chip 1, as shown in FIG.
Although the external shapes are exactly the same, there are four types (a), (b), (c), and (d) in which the electrode terminals 5, 6 are formed at different positions depending on the reagent or the production lot. That is, when different reagents are used, (a)
Is for blood sugar, (b) is for cholesterol, (c) is for lactic acid, and (c) is for uric acid. In addition, the calibration curve correction formulas corresponding to the manufacturing lots are made to correspond to the electrode terminal positions and the calibration curve correction formulas to be applied. When such a sensor chip 1 is mounted on the measuring device 2, the measuring device 2 immediately switches the switches 12, 13, 14, and 15 sequentially as described below, and establishes connection with the electrode terminals 5 and 6 so that conduction can be obtained. Detect the terminal. First, only the switches 13 and 14 are closed, and when a response is obtained, the sensor chip 1 is closed.
Can be specified as (a) in FIG. If no response is obtained, only the switches 13 and 15 are closed. At this time, if a response is obtained, the sensor chip can be identified as (b) in FIG. If a response is still not obtained, only the switches 12 and 14 are closed, and if a response is obtained, the sensor chip can be identified as (c) in FIG. If no response is obtained by the above operation, finally, the switch 12 and the switch 1
By closing 5 and detecting conduction, the sensor chip can be identified as (d) in FIG. It is not necessary to perform all the switching operations corresponding to the four types of the sensor chip 1 for the operation of switching the switches of the measuring device 2, and the switching operation can be completed when a conductive electrode terminal can be detected. As described above, the type of the sensor can be specified, and the measuring device automatically performs the measurement according to the reagent carried on the sensor chip, the setting of the calibration curve correction for the obtained measured value, and the like. In the above example, the measuring device 2 is provided with two pairs of connection terminals. However, the number of connection terminals can be increased. If there are N pairs (N is an integer of 2 or more), 2 N types of sensor chips can be determined. (Embodiment 2) Hereinafter, Embodiment 2 of the present invention will be described with reference to FIGS. In FIG.
Is a sensor chip for adding a liquid sample;
Indicates an enlarged view of a mounting portion of the measuring device 22 to which the sensor chip is mounted. The sensor chip 21 is made of a base material 23 obtained by press-punching a sheet of polyethylene resin or the like.
A reagent 24 reacting with the added liquid sample and electrode terminals 25 and 26 for detecting a reaction current obtained by the reaction with the reagent are formed on the upper part. Sensor chip 21
As shown in FIG. 4, although the external shape is exactly the same, the three types of (a), (b), and (c) are caused by differences in the calibration curve correction formulas due to differences in reagents or manufacturing lots. There are types. The difference from the first embodiment is that one electrode terminal 2 of the pair of electrode terminals of the sensor chip is used.
5 is formed at the same position, and the connection terminal of the measuring instrument 22 is also a common connection terminal 28 corresponding to the electrode terminal 25, and the other three connection terminals 29, 30, 31.
Are sequentially switched. The mounting portion of the measuring device 22 is provided with a connector 27 formed of resin so as to engage with the outer shape of the sensor chip.
5 and 26 so that four connection terminals 28 and 2 can be connected.
9, 30, 31 are formed. Reference numerals 32, 33, and 34 denote switches, and by connecting the switches, signal lines 37 connected to an electric circuit inside the measuring instrument 22 (not shown).
And the connection terminals 29, 30, and 31 can be selectively connected. Here, for example, the sensor chip 21 is
And switches the switches sequentially. Switch 3
If a response is obtained when 2 is connected, the sensor chip can be identified as (a) in FIG. When a response is obtained when the switch 33 is connected, the sensor chip can be identified as (b) in FIG. When a response is obtained when the switch 34 is connected, the sensor chip can be identified as (c) in FIG. Also in the case of this example, the switching operation of the switch can be completed when the connection terminal that is electrically connected to the electrode terminal of the sensor chip can be detected. Further, the type of the sensor can be determined by the number N of the other connection terminals that are not common.
As described above, the type of the sensor can be specified, and the measuring device automatically performs the measurement according to the reagent carried on the sensor chip, the setting of the calibration curve correction for the obtained measured value, and the like.

【発明の効果】以上のように、本発明のバイオセンサ測
定装置によれば、センサチップに形成する一対の電極端
子の形成位置を変え、また測定器側では電極端子の形成
位置の違いからセンサチップの種別を判別することによ
り、センサチップのケーシングなどの部材を共用した
り、その外形形状も共通にすることができ、コストの低
減を図ることができる。また検量線の補正式の設定につ
いても、特別に切り換え用チップ等を使った使用者の手
作業によらなくともよくなり、操作性の向上を図ること
が出来る。
As described above, according to the biosensor measuring apparatus of the present invention, the position of the pair of electrode terminals formed on the sensor chip is changed, and the sensor side is changed on the measuring instrument side due to the difference in the position of the electrode terminals. By discriminating the type of the chip, members such as the casing of the sensor chip can be shared, and the external shape can be made common, so that the cost can be reduced. Also, the setting of the correction formula of the calibration curve does not need to be manually performed by a user using a special tip for switching or the like, and operability can be improved.

【図面の簡単な説明】[Brief description of the drawings]

【図1】本発明の実施の形態1におけるバイオセンサ測
定装置を示す概略構成図
FIG. 1 is a schematic configuration diagram showing a biosensor measurement device according to a first embodiment of the present invention.

【図2】同バイオセンサ測定装置に使用するセンサチッ
プの平面図
FIG. 2 is a plan view of a sensor chip used in the biosensor measurement device.

【図3】本発明の実施の形態2におけるバイオセンサ測
定装置を示す概略構成図
FIG. 3 is a schematic configuration diagram illustrating a biosensor measurement device according to a second embodiment of the present invention.

【図4】同バイオセンサ測定装置に使用するセンサチッ
プの平面図
FIG. 4 is a plan view of a sensor chip used in the biosensor measurement device.

【符号の説明】[Explanation of symbols]

1,21 センサチップ 2,22 測定器 3,23 基材 4,24 試薬 5,6,25,26 電極端子 7,27 コネクタ 8,9,10,11、28,29,30,31 接続端
子 12,13,14,15,32,33,34 スイッチ 16,17,36,37 信号線
1,21 Sensor chip 2,22 Measuring device 3,23 Base material 4,24 Reagent 5,6,25,26 Electrode terminal 7,27 Connector 8,9,10,11,28,29,30,31 Connection terminal 12 , 13,14,15,32,33,34 Switch 16,17,36,37 Signal line

Claims (7)

【特許請求の範囲】[Claims] 【請求項1】 液体試料と試薬との反応により生じる電
気信号を検出するための一対の電極端子とを備えたセン
サチップ、及び前記センサチップ装着され、これらセン
サチップの電極端子と電気的接続をなす接続端子を備え
た測定器により、前記液体試料中の成分を電気化学的に
測定するバイオセンサ測定装置において、 前記センサチップの一対の電極端子は、前記センサチッ
プの種別毎に、互いに異なる位置に形成しており、前記
測定器の接続端子は、前記複数種のセンサチップのそれ
ぞれの電極端子に対応する位置に形成しており、これら
接続端子のうちのいずれの接続端子と前記センサチップ
の電極端子とが導通するかを測定器にて検出することに
より、前記センサチップの種別を判別するようにしたこ
とを特徴とするバイオセンサ測定装置。
1. A sensor chip having a pair of electrode terminals for detecting an electric signal generated by a reaction between a liquid sample and a reagent, and a sensor chip mounted on the sensor chip and electrically connecting the sensor chip to the electrode terminals. In a biosensor measuring device for electrochemically measuring a component in the liquid sample by a measuring device provided with a connecting terminal, a pair of electrode terminals of the sensor chip is located at different positions for each type of the sensor chip. The connection terminals of the measuring instrument are formed at positions corresponding to the respective electrode terminals of the plurality of types of sensor chips, and any of these connection terminals and the connection terminals of the sensor chip are formed. The biosensor measurement is characterized in that the type of the sensor chip is determined by detecting whether or not the electrode terminal is conductive with a measuring device. Apparatus.
【請求項2】 測定器は、複数の接続端子のうち、いず
れの接続端子とセンサチップの電極端子とが導通するか
を、前記複数の接続端子を順次切り換えることにより検
出するようにしたことを特徴とする請求項1に記載のバ
イオセンサ測定装置。
2. The method according to claim 1, wherein the measuring device detects which of the plurality of connection terminals is electrically connected to the electrode terminal of the sensor chip by sequentially switching the plurality of connection terminals. The biosensor measurement device according to claim 1, wherein
【請求項3】 測定器は、N(N>2以上の整数)対の
接続端子を備えており、最大で2N種類のセンサチップ
の種別を判別可能であることを特徴とする請求項2に記
載のバイオセンサ測定装置。
3. The measuring device has N (N> 2 or more integer) pairs of connection terminals, and is capable of discriminating a maximum of 2 N types of sensor chips. A biosensor measuring device according to item 1.
【請求項4】 センサチップの一対の電極端子のうち、
その一方を、センサチップの種別に関わらず同じ位置に
形成し、測定器の接続端子は、前記同じ位置に形成した
電極端子に対応する接続端子を、共通としたことを特徴
とする請求項1または2に記載のバイオセンサ測定装
置。
4. A pair of electrode terminals of the sensor chip,
2. One of the sensor chips is formed at the same position irrespective of the type of the sensor chip, and a connection terminal of the measuring device has a common connection terminal corresponding to the electrode terminal formed at the same position. Or the biosensor measurement device according to 2.
【請求項5】 測定器の接続端子のうち、共通としない
他方の接続端子をN個形成することにより、N種類のセ
ンサチップを判別可能にしたことを特徴とする請求項4
に記載のバイオセンサ測定装置。
5. The sensor device according to claim 4, wherein N of the other connection terminals that are not common among the connection terminals of the measuring device are formed so that N types of sensor chips can be identified.
A biosensor measuring device according to item 1.
【請求項6】 センサチップは、液体試料中の測定すべ
き成分に応じて、担持する試薬の種類及び電極端子の形
成位置を変えていることを特徴とする請求項1〜5のい
ずれかに記載のバイオセンサ測定装置。
6. The sensor chip according to claim 1, wherein the type of the reagent to be carried and the position of the electrode terminal are changed according to the component to be measured in the liquid sample. The biosensor measurement device according to claim 1.
【請求項7】 測定器にて得られる測定値をセンサチッ
プの出力特性に応じて補正するために、前記センサチッ
プの出力特性に応じて電極端子を異なる位置に形成して
いることを特徴とする請求項1〜5のいずれかに記載の
バイオセンサ測定装置。
7. An electrode terminal is formed at a different position according to an output characteristic of the sensor chip in order to correct a measurement value obtained by a measuring device according to an output characteristic of the sensor chip. The biosensor measurement device according to claim 1.
JP2000093178A 2000-03-30 2000-03-30 Biosensor measuring apparatus Pending JP2001281197A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2000093178A JP2001281197A (en) 2000-03-30 2000-03-30 Biosensor measuring apparatus
PCT/JP2001/002733 WO2001073420A1 (en) 2000-03-30 2001-03-30 Biosensor measuring device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000093178A JP2001281197A (en) 2000-03-30 2000-03-30 Biosensor measuring apparatus

Publications (2)

Publication Number Publication Date
JP2001281197A true JP2001281197A (en) 2001-10-10
JP2001281197A5 JP2001281197A5 (en) 2007-05-17

Family

ID=18608397

Family Applications (1)

Application Number Title Priority Date Filing Date
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Country Status (2)

Country Link
JP (1) JP2001281197A (en)
WO (1) WO2001073420A1 (en)

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