JP2001122746A - Tooth paste composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a tooth paste composition that manifests sufficient stain- removing effect without abrasion of teeth, particularly dentine. SOLUTION: This tooth paste composition includes 2 or more kinds of precipitated silica having >=20 RDA values where the RDA value is <=60, the PCR value is <=50 and the ratio of PCR/RDA is >=1.2 as the total composition.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a dentifrice composition. More specifically, the present invention relates to a dentifrice composition having a low abrasive power while maintaining a high stain removal effect.

[0002]

2. Description of the Related Art Stain is a pigmentary deposit on teeth which is thought to be caused by fungicides such as chlorhexidine, tannin-based substances contained in tea, and metals such as iron. It is. As a method for removing stains, a method is generally used in which an oral composition such as a dentifrice containing an abrasive is contained in the mouth via a toothbrush and brushed. Regarding the removal of colored stains by this method, stains are mainly removed by the action of an abrasive, and it is said that the use of an abrasive having a high abrasive force has a higher stain removing effect. However, the use of an abrasive having a high abrasive power may cause the teeth, particularly the dentin of the teeth, to be worn out more than necessary. Therefore, the development of an abrasive and a dentifrice having a high cleaning power but a low abrasive power has been required. Have been tried.

[0003] Abrasives and dentifrices which try to keep the cleaning power low while keeping the cleaning power high are disclosed in Japanese Patent Application Laid-Open No. 11-5 / 1991.
04918, JP-A-11-504919, JP-A-11-504920, JP-A-11-
1994456, JP-A-10-175834, JP-A-10-31647, JP-T-10
-511684, JP-A-8-165108, JP-A-2514157, JP-A-6-2
No. 39722, and the like. However, the abrasive power of the oral composition described therein which has a sufficient stain removing effect mainly has an RDA value of more than 60, and is used for teeth, especially dentin. Is not sufficiently low. Therefore, there has been a demand for an oral composition which has a sufficiently low abrasive power so as not to abrade teeth or dentin and maintains a sufficient stain removing effect.

[0004]

SUMMARY OF THE INVENTION It is an object of the present invention to provide a dentifrice composition in which damage to or abrasion of teeth, particularly dentin, is sufficiently reduced while keeping the effect of removing stains high.

[0005]

Means for Solving the Problems The present inventors have conducted intensive studies in view of such a current situation, and as a result, blended two (in some cases, two or more) precipitated silicas having different characteristic values. Thereby, it is possible to provide a dentifrice composition capable of suppressing the polishing force to an intermediate level between both silicas, while maintaining the same stain removal effect as when only one of the silicas having a higher stain removal effect is blended. And completed the present invention.

That is, the present invention relates to a dentifrice composition comprising two or more precipitated silicas having a radioactive dentin abrasion (RDA) value of 20 or more, and comprising a total of the composition. RDA value is less than or equal to 60 and Pellicle Cleaning Rati
o (PCR) is 50 or more
A dentifrice composition having an RDA ratio of at least 1.2.

According to the dentifrice composition of the present invention, there is provided a dentifrice composition having a high stain removing effect without abrading teeth, particularly dentin of the teeth.

[0008]

DETAILED DESCRIPTION OF THE INVENTION The abrasive used in the dentifrice composition of the present invention is two or more precipitated silicas having different RDA values of not less than 20, and when formulated, the abrasive of the dentifrice composition of the present invention.
The RDA value is 60 or less, the PCR value is 50 or more, and the ratio of PCR / RDA is 1.2 or more. Such precipitated silica has a weight average particle size of 5 to 15 μm and an oil absorption of 110 ml / 100 g to 135 ml / 100 g.
g, precipitated silica having an RDA value of 30 to 70 (hereinafter referred to as “precipitated silica A”), a weight average particle size of 5 μm to 15 μm, and an oil absorption of 100 ml / 100 g.
~ 130ml / 100g, RDA value is 70 ~ 13
0 (precipitated silica B)
Is preferred.

These precipitated silica A and precipitated silica B
Is a ratio of 90:10 to 50:50, preferably 8
0:20 to 60:40 ratio, most preferably 7
The dentifrice composition of the present invention can be mixed in a ratio of 5:25, and the total amount of the dentifrice composition of the present invention is 1 in the above range.
The dentifrice composition of the present invention may be contained in a dosage form such as toothpaste or the like in an amount of 7 to 30% by weight, and in a powdered toothpaste dosage form of 9 to 30% by weight.
It can be blended at a high level of about 5% by weight. When the ratio of precipitated silica A to precipitated silica B is more than 90:10, the polishing power is sufficiently low, but the stain removal effect is not sufficiently high. Although the stain removal effect is sufficiently high, it is not preferable because the polishing power is not sufficiently low.

Here, the weight average particle size of the precipitated silica is a value measured according to the method described in JP-A-5-208808. In addition, radioactive dentin polishing (RD
A) Value refers to the Journal of Dental R by Hefferren et al.
esearch, 55: 563-573, 1976; U.S. Pat.
It is measured according to the method described in U.S. Pat. No. 5,583, 4,420,312 and 4,421,527. In addition, pericardial wash ratio (PCR) values were determined by Stooky et al. In the Journal of Dental Research,
61: 1236-1239, 1982. Further, the oil absorption is determined by the ASTM spatula kneading method (American Society of Test Mat).
erial Standards D. 281).

The precipitated silicas A and B according to the present invention may be, for example, an alkali or alkaline earth metal salt,
A prepolymerization is carried out by adding the solution to an alkali metal silicate such as sodium silicate.The reaction is carried out by heating to a certain temperature range under a certain pH range, and then an acidifying agent is added to precipitate the silica. It can be manufactured by filtering, washing with water and drying. Here, various reaction parameters, in particular, the rate of addition of the reactants, the concentration of the reactants, the reaction p
H, physical properties of precipitated silicas A and B can be changed by changing the reaction temperature (Japanese Patent Laid-Open No. 49-94).
712, JP-A-50-64198 and JP-A-50-65497).

The dentifrice composition of the present invention can be adjusted to a dosage form such as toothpaste, liquid dentifrice, lubricating dentifrice, powdered dentifrice, etc. by a conventional method. The following suitable components commonly used can be blended, for example, bases such as abrasives, binders, pH adjusters, surfactants, wetting agents, sweeteners, flavors, preservatives and the like other than those described above. Further, various active ingredients can be blended within a range that does not impair the effects of the present invention.

For example, in dentifrices, as abrasives other than the above-mentioned abrasives, dibasic calcium phosphate dihydrate and anhydrate, calcium phosphate, tertiary calcium phosphate,
Calcium carbonate, calcium pyrophosphate, aluminum hydroxide, alumina, silicic acid anhydride, silica gel, aluminum silicate, insoluble sodium metaphosphate, tribasic magnesium phosphate, magnesium carbonate, calcium sulfate, polymethyl methacrylate, bentonite, zirconium silicate, Hydroxyapatite, synthetic resin and the like can be used. These abrasives may be used alone or in combination of two or more, and the amount of the abrasive is different from that of the precipitated silica and the amount of the dentifrice relative to the total amount of the dentifrice composition of the present invention. In the case, it is 5% to 90% by weight, and in the case of toothpaste, it is 5% to 50% by weight.

Examples of the foaming agent include mainly anionic surfactants. For example, the alkyl group such as sodium lauryl sulfate and sodium myristyl sulfate has 8- to 8-carbon atoms.
18, higher alkyl sulfate salts, N-long chain acyl amino acid salts, α-olefin sulfonate salts, higher fatty acid sodium monoglyceride monosulfate, N
-Methyl-N-palmitoyl tauride salt and the like can be blended. Many of these anionic surfactants have a high stain removing effect by chemical dissolution, and it is particularly preferable to add sodium lauryl sulfate since the stain removing effect is synergistically enhanced. These anionic surfactants may be used alone or in combination of two or more, and the amount thereof is usually from 0.001% by weight to 5% by weight based on the total amount of the dentifrice composition of the present invention. % By weight, preferably 0.01% to 2% by weight.

The dentifrice composition of the present invention may further comprise a cationic surfactant, a nonionic surfactant or a zwitterionic surfactant which is generally used in an oral composition in addition to the above-mentioned anionic surfactant. May be used alone or two or more of them may be used in combination. The compounding amount is usually 0.001% by weight to 5% by weight based on the total amount of the dentifrice composition of the present invention.
Preferably it is 0.01% to 2% by weight.

Examples of the binder include cellulose derivatives such as carboxymethyl cellulose, alkali metal alginate such as sodium alginate, propylene glycol alginate, xanthan gum, tragacanth gum, gum karaya, gum arabic, gum gum such as carrageenan, polyvinyl alcohol, polyalcohol and the like. A synthetic binder such as sodium acrylate, carboxyvinyl polymer, polyvinylpyrrolidone or the like may be used alone or
More than one kind may be used in combination, and the compounding amount is usually 0.3% by weight to 5% by weight based on the total amount of the dentifrice composition of the present invention, alone or as a total of two or more kinds.

Further, as a flavoring agent, menthol, carvone, anethole, eugenol, methyl salicylate, limonene, ocimene, n-decyl alcohol, citronellol, α-terpineol, methyl acetate,
Citronellyl acetate, methyl eugenol, cineol, linalool, ethyl linalool, crocodile, thymol, spearmint oil, peppermint oil, lemon oil, orange oil, sage oil, rosemary oil, cinnamon oil, pimento oil, diatom oil, perilla oil, winter Green oil, clove oil, eucalyptus oil and the like. These flavoring agents may be used alone or in combination of two or more kinds, and the compounding amount thereof is 0.05% by weight based on the total weight of the dentifrice composition of the present invention, alone or as a total amount of two or more kinds. % To 10% by weight, preferably 0.1%
% To 5% by weight.

Examples of sweeteners include saccharin sodium, acesulfame K, stevioside, glycyrrhizin, perillartin, thaumatin, aspartyl phenylalanine methyl ester, sucralose, xylitol, palatinose, palatinit, erythritol,
Maltitol and the like. These sweeteners may be used alone or in combination of two or more, and the compounding amount thereof may be 0.01 or more as a total amount of one or more of the total amount of the dentifrice composition of the present invention. % To 5% by weight.

The wetting agents include sorbitol, glycerin, ethylene glycol, propylene glycol,
Examples include 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylit, maltitol, lactit, and the like. These humectants
The dentifrice composition of the present invention may be used singly or in combination of two or more kinds. .

Further, pH adjusters such as sodium hydrogen phosphate, citric acid and sodium citrate; bactericides such as chlorhexidine gluconate, cetylpyridinium chloride and triclosan; dextranase, amylase, protease, mutanase, lysozyme, lytic enzyme (Litec enzyme), etc., alkali metal monofluorophosphates such as sodium monofluorophosphate and potassium monofluorophosphate, fluorides such as sodium fluoride and stannous fluoride, tranexamic acid and epsilon aminocaproic acid , Aluminum chlorohydroxy allantoin, dihydrocholesterol, vitamin E
Active ingredients such as derivatives, glycyrrhizinates, glycyrrhetinic acid, glycerophosphate, chlorophyll, sodium chloride, caropeptides, and water-soluble inorganic phosphate compounds may be used alone or in combination of two or more.

[0021]

EXAMPLES The present invention will be described in more detail with reference to Test Examples and Examples below, but the present invention is not limited thereto. Unless otherwise specified, [%] indicates [% by weight].

The dentifrice compositions of Example 1-2 and Comparative Example 1-2 shown in Table 1 below were prepared and evaluated as follows. Example 1-2 is a dentifrice composition of the present invention,
Comparative Example 1 was prepared by mixing only precipitated silica belonging to precipitated silica A as an abrasive, and Comparative Example 2 was prepared by mixing only precipitated silica belonging to precipitated silica B as an abrasive,
In each case, the total content of the abrasive was adjusted to be constant.

Test Example 1 Evaluation of Polishing Characteristics Evaluation of the polishing characteristics of dentifrices and abrasives was carried out according to the article by Hepharen et al. (Hefferren et.al., Journal of Dental Research).
55: 563-573, 1976) by measuring the RDA (Radioactive Dentine Abrasion) value. This method is an authorized method for measuring the polishing amount of a dentifrice or an abrasive, and detailed procedures and the like are described in JP-A-62-87507. For typical dentifrices, the RDA value is 60
To about 120.

Test Example 2 Stain Removal Effect The stain removal effect of dentifrices and abrasives was determined by the article by Stooky et al., Journal of Dental Rese.
arch, 61: 1236-1239, 1982) by measuring the PCR (Pellicle Cleaning Ratio) value based on the method described in the above. This method is an authorized method for measuring the polishing amount of a dentifrice or an abrasive, and detailed procedures and the like are described in JP-A-6-239722. For a typical dentifrice, the PCR value is in the range of about 60 to 100.

[0025]

[Table 1] * Precipitated silica 1 (precipitated silica belonging to precipitated silica A):
Weight average particle size 10μm, RDA value 50, oil absorption 120ml
/ 100 g ** precipitated silica 2 (precipitated silica belonging to precipitated silica B):
Weight average particle size 9 μm, RDA value 90, oil absorption 115 ml /
100g

From the results shown in Table 1, it is found that blending two kinds of precipitated silicas having different characteristic values as an abrasive is equivalent to blending only one of the precipitated silicas having a higher stain removing effect (precipitated silica A). It can be seen that the polishing force (RDA value) can be suppressed to a value between both of the settled silicas while maintaining the stain removal effect (PCR value). That is, the RDA value of 32 is sufficient in Comparative Example 2, but the PCR value is not sufficient of 48, whereas the PCR value of Example 1-2 is sufficient (the high stain removal effect is maintained). At the same time, note that the RDA values are 49 and 39, and the polishing power is kept low.

Example 3 Ingredients Compounding amount (% by weight) Precipitated silica 1 15.00 Precipitated silica 2 4.00 Thickening silica 2.00 Carboxymethylcellulose 1.00 70% solution of sorbitol 60.00 Sodium lauryl sulfate 1.20 Sodium saccharin 0.15 Titanium oxide 0.50 Fragrance 0.85 Sodium fluoride 0.20 Purified water balance Total 100.00 RDA value 36 PCR value 68

Example 4 Ingredients Compounding amount (% by weight) Precipitated silica 1 12.00 Precipitated silica 2 5.00 Thickening silica 2.00 Carboxymethylcellulose 1.00 70% solution of sorbitol 60.00 Sodium lauryl sulfate 1.20 Sodium saccharin 0.15 Titanium oxide 0.50 Fragrance 0.85 Sodium fluoride 0.20 Purified water balance Total 100.00 RDA value 37 PCR value 73

[0029]

According to the present invention, it is possible to provide a dentifrice composition exhibiting an excellent stain removing effect without abrading the teeth, particularly the dentin of the teeth.

Claims (8)

[Claims] 1. A dentifrice composition comprising two or more precipitated silicas having an RDA value of 20 or more, wherein the RDA value of the whole composition is 60 or less, and the PCR value is 50 or more and the PCR value is 50 or more. A dentifrice composition having a / RDA ratio of 1.2 or more. 2. The dentifrice composition according to claim 1, wherein the ratio of PCR / RDA is 1.5 or more. 3. The method according to claim 1, wherein at least one of the precipitated silica has a particle size of 5 μm.
m to 15 μm weight average particle size, 110 ml / 100
3. Precipitated silica having an oil absorption of g to 135 ml / 100 g and an RDA value of 30 to 70 (hereinafter referred to as precipitated silica A).
A dentifrice composition as described. 4. The method according to claim 1, wherein at least one of the precipitated silica is 5 μm.
m to 15 μm weight average particle size, 100 ml / 100
The dentifrice composition according to claim 1 or 2, wherein the dentifrice composition is precipitated silica having an oil absorption of from 0.1 g to 130 ml / 100 g and an RDA value of from 70 to 130 (hereinafter referred to as precipitated silica B). 5. The dentifrice composition according to claim 3, wherein the precipitated silica contains at least precipitated silica A and precipitated silica B. 6. The precipitated silica includes precipitated silica A and precipitated silica B, wherein the precipitated silica A and the precipitated silica B are in a ratio of 90:10 to 50:50 in a total amount of 5% by weight to 99% by weight. The dentifrice composition according to claim 5, wherein the RDA value of the composition as a whole is 25 to 60 and the PCR value is 50 to 100. 7. The dentifrice composition according to claim 6, comprising the precipitated silica A and the precipitated silica B in a total amount of 7 to 30% by weight. 8. When 20% by weight of the precipitated silica A alone is added to a toothpaste as an abrasive, the RDA value of the toothpaste is 20 to 50 and the PCR value of the toothpaste is 20 to 60. Precipitated silica A, wherein the precipitated silica B is used alone as an abrasive in a toothpaste in an amount of 20% by weight.
8. The dentifrice composition according to claim 7, wherein the toothpaste is precipitated silica B such that the RDA value of the toothpaste is 60 to 90 and the PCR value of the toothpaste is 60 to 100.