JP2001009029A - Method for washing dialysis apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To make it possible to wash approximately the entire area of a water supply passage which cannot heretofore be washed. SOLUTION: At the time of washing of the dialysis apparatus 1, stop valves V1 and V3 are closed and a stop valve V10 is opened and further, three-way selector valves V5 to V8 are positioned to prescribed changeover positions. As a result, both recovering chambers 9 and 9' are made to communicate with each other and simultaneously both supply chambers 7 and 7' are made to communicate with each other via a liquid feed passage 12, a bypass passage 35 and a water supply passage 11. As a result, the washing routes (shown by bold lines) through which both supply chambers 7 and 7' communicate with each other are formed. The washing liquid interposed in the washing routes is passed by operating a pump P1 in this state.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for cleaning a dialysis device.

[0002]

2. Description of the Related Art Conventionally, the following method is known as a method for cleaning a dialysis device. That is, a first chamber for supplying and collecting a dialysate to a dialyzer with a supply chamber and a recovery chamber is provided.
Processing means, a second processing means having a supply chamber and a recovery chamber for supplying and collecting dialysate to the dialyzer, and connected to the supply chambers of the first processing means and the second processing means to supply fresh dialysate. A water supply passage for supplying water for production from a supply source, a pump provided in the water supply passage to supply water of the supply source to each of the supply chambers, a pump and a supply source in the water supply passage; An on-off valve provided between the first and second processing units, for opening and closing a water supply passage; a fresh dialysate supply passage for communicating the supply chambers of the first and second processing units with the dialyzer;
A drainage passage for the processed dialysate, which communicates the dialyzer with the collection chambers of the first processing means and the second processing means, is connected to the collection chambers of the first processing means and the second processing means, and is connected to the collection chamber. A discharge passage for discharging the treated dialysate to the outside,
With the end of the liquid supply passage connected to the dialyzer and the end of the drain passage connected to the dialyzer being in communication with each other, the washing liquid supplied to the supply chambers of both the processing means is sequentially discharged. A method of cleaning a dialysis device which is circulated through a liquid supply passage to wash the inside of the circulated passage is known (for example, Japanese Patent Publication No. 6-11314). In such a conventional method for cleaning a dialysis device, when cleaning the dialysis device, the cleaning solution is circulated in the same passage as the dialysis solution flows during dialysis, and the inside of those passages is washed. ing.

[0003]

In the above-described conventional cleaning apparatus, one end of the cleaning passage is connected to a position between the pump and each supply chamber in the water supply passage. The cleaning liquid is introduced into each supply chamber via a water supply passage between the supply chamber and each supply chamber, and the cleaning liquid is further circulated from each supply chamber into the liquid supply passage. Therefore, in the conventional washing method, the inside of the water supply passage from the point where one end of the washing passage in the water supply passage is connected to the water supply source is not washed. Therefore, an object of the present invention is to provide a cleaning method capable of cleaning the inside of a water supply passage that has not been cleaned by the conventional cleaning method.

[0004]

That is, according to the present invention, in the above-mentioned method for cleaning a dialysis device, a bypass for communicating a water supply passage located between the on-off valve and the pump with the liquid supply passage or the drainage passage is provided. A water passage provided between the open / close valve and the pump by a bypass passage, wherein the open / close valve is closed when necessary, and a communication passage for communicating the collection chambers of the first and second processing units with each other is provided. The passage and the liquid supply passage or the drain passage, and
Operating the pump in a state where the collection chambers of the first processing means and the second processing means are communicated with each other by the communication path,
The method includes a washing step of circulating the washing liquid from the supply chamber to the water supply passage to wash the inside thereof.

[0005]

According to the above-described structure, the inside of the water supply passage, which cannot be cleaned by the conventional cleaning method, can be cleaned with the cleaning liquid.

[0006]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below with reference to the illustrated embodiment. In FIGS. 1 to 7, a dialysis apparatus 1 includes a dialyzer 2 for performing dialysis, A first dialysate container 3 and a second dialysate container 4 are provided as processing means for collecting a liquid. The dialyzer 2 is conventionally known, and introduces blood, which is a liquid to be treated, into the dialyzer 2 through a supply path 5 and discharges the blood to the outside through a discharge path 6. The first dialysate container 3 and the second dialysate container 4 as processing means are arranged side by side with respect to the dialyzer 2, and the dialysate containers 3 and 4 alternately enter the dialysate container 2. The dialysate is supplied and the processed dialysate is collected from the dialyzer 2. The configuration of each of these dialysate containers 3, 4 is also conventionally known. The inside of both dialysis fluid containers 3 and 4 is provided with a supply chamber 7 (7 ′) and a variable volume chamber 8 by a pair of left and right diaphragms.
(8 ') and a collection chamber 9 (9'). The dialysis device 1 includes a water supply passage 11, and an upstream end 11a of the water supply passage 11 is connected to a water supply source (not shown). Further, the portion near the dialysate containers 3, 4 on the downstream side of the water supply passage 11 is branched into two, and the two downstream end portions 11b, 1
1b 'is supplied to the supply chamber 7 (7') of each of the dialysate containers 3, 4 described above.
Connected to Water is supplied into the supply chamber 7 (7 ') of each of the dialysate containers 3, 4 via the water supply passage 11.

An on-off valve V1 is provided on the upstream side of the water supply passage 11, and a pump P1 for supplying water downstream of the on-off valve V1 is provided.
Thus, water is supplied to the supply chambers 7, 7 'of the respective dialysate containers 3, 4. Further, an on-off valve V2 is provided downstream of the pump P1. A three-way switching valve V5 is provided in the water supply passage 11 between the downstream branch point in the water supply passage 11 and the supply chamber 7 of the first dialysate container 3.
And a water supply passage 1 between the branch point of the water supply passage 11 and the supply chamber 7 ′ of the second dialysate container 4.
1 is provided with a three-way switching valve V7. The on-off valves V1, V
2. The operations of the two three-way switching valves V5 and V7 and the pump P1 are controlled by a control device (not shown). Further, the dialysis device 1 is provided with a liquid supply passage 12 so that the supply chambers 7, 7 'of the respective dialysate containers 3, 4 can communicate with the dialyzer 2. That is, the upstream side of the liquid supply passage 12 is branched into two, one of these two upstream end portions 12b is connected to the three-way switching valve V5, and the two branched upstream sides are connected. The other end 12b 'is connected to the three-way switching valve V7. The downstream end 12 a of the liquid supply passage 12 is detachably connected to the dialyzer 2. The downstream end 12a of the liquid supply passage 12 is connected to an upstream end 13a of a drainage passage 13 described later by a conventionally known connection plug 14 when the dialysis device 1 is washed. I have. The configuration of the connection plug 14 is described in, for example,
It is already known in US Pat.

A three-way switching valve V9 is provided downstream of the liquid supply passage 12. One end of the bypass passage 15 is connected to one port of the three-way switching valve V 9, and the other end of the bypass passage 15 is connected to the drain passage 13. The operation of the three-way switching valve V9 is controlled by a control device (not shown).
When located at the switching position, the upstream liquid supply passage 12 communicates with the downstream end 12a. When the switching valve V9 is located at the second switching position, the upstream liquid supply passage 12 communicates with the bypass passage 15. It has become. Next, when the three-way switching valves V5 and V7 of the water supply passage 11 are located at the first switching position, the water supply source communicates with the supply chambers 7 and 7 'via the water supply passage 11. At the same time, communication between the supply chambers 7, 7 'and the liquid supply passage 12 is prevented. On the other hand, when the three-way switching valves V5 and V7 are located at the second switching position, communication between the water supply source and each of the supply chambers 7 and 7 'is prevented, and at the same time, the supply chamber is supplied via the liquid supply passage 12. 7, 7 ′ and the dialyzer 2 communicate with each other. Further, the dialysis device 1 includes a stock solution passage 16 and a stock solution passage 17, and one ends 16a and 17a of both the passages 16 and 17 are connected to the water supply passage 11 downstream of the on-off valve V2. The other end 16b of the undiluted solution passage 16 is connected to A
The other end 17b of the stock solution passage 17 is adapted to be connected to a tank storing the B solution which constitutes the dialysate. Stock solution passage 1
The operations of the on-off valves V13 and V14 for opening and closing the valves 6 and 17 are controlled by a control device. When the three-way switching valves V5 and V7 are located at the first switching position and the on-off valves V13 and V14 are open, water is supplied into the supply chambers 7 and 7 'via the water supply passage 11. At the same time, the liquid A and the liquid B are supplied into the supply chambers 7 and 7 ′ through the water supply passage 11 and the undiluted liquid passage 16 and the undiluted liquid passage 17 connected thereto, and the fresh dialysate is supplied into the supply chambers 7 and 7 ′. It is being manufactured. On the other hand, the three-way switching valves V5 and V
When 7 is in the second switching position, the supply chamber 7,
Fresh dialysate produced in 7 ′ is supplied to the dialyzer 2 through the liquid supply passage 12. The control device is
The three-way switching valves V5 and V7 are operated synchronously, but when one is located at the first switching position, the other is located at the second switching position, and when one is located at the second switching position, the other is at the first switching position. It is controlled alternately so that it is located at the position.

The dialysis apparatus 1 further includes a washing passage 18, one end 18a of the washing passage 18 is connected to the water supply passage 11 immediately upstream of the on-off valve V2, and the other end is divided into two. It has branched. One of the ends of the two branch passages 18C is connected to the other end 1 of the stock solution passage 16.
6b, and can be connected to the other end 17b of the stock solution passage 17 at the other end of the two branch passages 18C. Further, an on-off valve V11 is provided on the upstream side of the washing passage 18, and
A draw-in passage is provided between the on-off valve V11 and the branch passage 18c, and an on-off valve V12 is provided in the draw-in passage, and a tank storing the undiluted washing liquid can be connected to the end 18b. The operation of these on-off valves V11 and V12 is also controlled by a control device, and the control device closes these on-off valves V11 and V12 when dialysis is performed by the dialyzer 2. In addition, this washing passage 1
Numeral 8 is for supplying the cleaning liquid to the water supply passage 11 via the raw liquid passages 16 and 17, and a section from one end 18a to the drawing-in passage is provided in the raw liquid passages 16 and 17 in the rinsing step in the cleaning operation. Water is supplied from the water supply passage 11 to wash out the cleaning liquid. A filter 21 for filtering water, a pressure reducing valve 22 for reducing the pressure of water, and a pressure gauge 23 for measuring water pressure are provided upstream of the on-off valve V1 in the water supply passage 11. Downstream of the on-off valve V1 in the water supply passage 11, a temperature sensor 24 for measuring water temperature, a flow control valve 25 for adjusting the flow rate of water in the water supply passage 11, and a heat exchanger 26 are provided. And a heater 2 for heating water further downstream thereof
7. A buffer tank 28 is sequentially provided. Further, a deaeration tank 31 for bleeding air from the water in the water supply passage 11 is provided immediately downstream of the pump P1 in the water supply passage 11, and the deaeration tank 31 is connected via a deaeration passage 55. And is communicated with a discharge passage 47 to be described later. The downstream side of the pump P1 in the water supply passage 11 and the buffer tank 28
Are connected by a bypass passage 32. Further, a portion of the water supply passage 11 on the downstream side of the deaeration tank 31 and a portion on the upstream side of the temperature sensor 24 are communicated by another bypass passage 33. A relief valve 34 is provided in the bypass passage 33.

Next, the three-way switching valve V in the liquid supply passage 12
9 is provided with a pressure sensor 36 for detecting the pressure of the fresh dialysate flowing through the liquid supply passage 12, and the flow rate of the fresh dialysate flowing through the liquid supply passage 12 is provided upstream of the pressure sensor 36. A flow sensor 37 for detection is provided, and a flow regulating valve 38 is further provided upstream thereof. Further, a sample port 41 for extracting a fresh dialysate in the liquid supply passage 12 as a sample is provided upstream of the flow control valve 38 in the liquid supply passage 12, and a fresh dialysate is further upstream thereof. Are provided, and the detection results of these sensors 42 and 43 are always transmitted to the control device. Further, buffer tanks 44 and 45 are sequentially provided upstream of the concentration sensor 43 in the liquid supply passage 12. Next, the dialysis device 1 is provided with a drainage passage 13 so that the dialyzer 2 can communicate with the collection chambers 9 and 9 ′ of the dialysate containers 3 and 4. That is, the drainage passage 13
Is connected to the dialyzer 2 detachably. The downstream side of the drainage passage 13 is branched into two, and one of the two branched downstream ends 13b is connected to the collection chamber 9 of the first dialysate container 3. The other downstream end 13b '
Is connected to the recovery chamber 9 ′ of the second dialysate container 3. A pump P2 is provided in the middle of the drainage passage 13, and the pump P2 supplies fresh dialysate in the supply chambers 7 and 7 'of the dialysate containers 3 and 4 to the dialyzer 2 while treating the dialyser 2. Can be collected in the collection chambers 9 and 9 '. Further, a check valve 51 is provided in the middle of the drainage passage 13 on the upstream side of this. The operation of the pump P2 is controlled by a control device. A three-way switching valve V is provided at a location in the drainage passage 13 between the downstream branch point and the collection chamber 9.
6 is provided, and a three-way switching valve V8 is provided at a position between the branch point in the drainage passage 13 and the recovery chamber 9 '.

Further, the dialysis apparatus 1 is provided with a discharge passage 47, and a downstream end 47a of the discharge passage 47 is connected to a drainage recovery tank (not shown). Discharge passage 47
Is branched into two, one of the branched ends 47b is connected to the three-way switching valve V6, and the other branched end 47b 'is connected to the three-way switching valve V8. Connected to An on-off valve V3 is provided in the middle of the discharge passage 47, and a blood leak sensor 48 is provided downstream thereof. When detecting that the processed dialysate in the discharge passage 47 contains blood, the blood leak sensor 48 transmits the fact to the control device. The operation of the two three-way switching valves V6, V8 and the opening / closing valve V3 is controlled by a control device. Three-way switching valve V
When V6 and V8 are located at the first switching position, communication between the collection chambers 9 and 9 'and the drain passage 13 is prevented, and at the same time, communication between the collection chambers 9 and 9' and the discharge passage 47. I do.
Therefore, in this state, the processed dialysate in the collection chambers 9 and 9 ′ can be discharged to the drain collection tank via the discharge passage 47. On the other hand, the three-way switching valves V6 and V8
When located in the switching position, each collection chamber 9, 9 '
And the drain passage 13 communicate with each other, and at the same time, each of the collecting chambers 9 and 9 ′
Communication with the discharge passage 47 is prevented. Therefore, in this state, the collection chambers 9 and 9 ′ communicate with the dialyzer 2 through the drainage passage 13, and the dialysate in the dialyzer 2 through the drainage passage 13 is treated. , 9 '. In addition,
The control device operates the three-way switching valves V6 and V8 in synchronization with each other. When one of the three-way switching valves V6 and V8 is located in the first switching position, the other is located in the second switching position, and when the one is located in the second switching position, the other is located. Are alternately controlled so as to be located at the first switching position. The switching between the three-way switching valves V6 and V8 and the three-way switching valves V5 and V7 is performed each time the flow rate sensor 37 detects that the flow of the liquid in the liquid supply passage 12 has stopped.

A deaeration tank 52 is provided in the drain passage 13 immediately downstream of the pump P2.
It communicates with the discharge passage 47 via the deaeration passage 53.
An opening / closing valve V4 is provided in the deaeration passage 53. The operation of the on-off valve V4 is also controlled by the control device. A bypass passage 56 is provided in the drain passage 13 on the upstream side of the pump 51 and on the downstream side of the deaeration tank 52, and a relief valve 57 is provided in the bypass passage 56. Further, one end of the bypass passage 35 is connected to a position further upstream of the connection end of the bypass passage 56 on the upstream side of the pump P2 in the drainage passage 13, and the other end is connected to the water supply passage 11.
The water supply passage 11 and the drain passage 13 are connected between the connection end of the bypass passage 33 on the upstream side and the on-off valve V1.
And the communication. The on-off valve V1 is provided in the bypass passage 35.
0 is provided, and when bleeding air from the deaeration tank 52 in the preparation stage of the dialysis operation, the on-off valve V10 is opened to send water from the water supply passage 11 to the drain passage 13 so as to open and close. The valve V4 is opened, the pump P2 is operated, and the water supplied through the bypass passage 35 supplies water to the deaeration tank 52.
The air accumulated inside is pushed out to the discharge passage 47 through the deaeration passage 53. Thus, when the on-off valve V4 is opened, the volume balance between the supply chamber 7 (7 ') and the recovery chamber 9 (9') is lost, and the supply chamber 7 (7 '), the liquid supply passage 12,
The closed system formed by the drain passage 13 and the collection chamber 9 (9 ') is prevented from becoming negative pressure. In addition, the bypass passage 3
The connection of one end of 5 may be the liquid supply passage 12 upstream of the discharge passage 13 instead of the discharge passage 13. Next, silicone oil is sealed in the variable volume chambers 8 and 8 'of each of the dialysate containers 3 and 4, and a pair of left and right diaphragms in each of the dialysate containers 3 and 4 are moved in association with each other. Like that. That is,
When the volume of the supply chamber 7 (7 ') of each of the dialysate containers 3, 4 is increased, the volume of the recovery chamber 9 (9') is reduced in conjunction therewith. 7 (7 ')
When the volume of the collection chamber 9 decreases,
The volume of (9 ') is expanded.

Each of the variable volume chambers 8, 8 'is communicated with the cylinder chamber of each of the cylinder devices 46, 46', and the control device causes the pistons of the cylinder devices 46, 46 'to move forward and backward. I have. by this,
By adjusting the amount of silicone oil in each of the variable volume chambers 8 and 8 ', the volume can be adjusted. The cylinder devices 46 and 46 'are controlled so that the volumes of the variable volume chambers 8 and 8' are reduced when the pair of left and right diaphragms goes right. As a result, the collection rooms 9 and 9 '
Is larger than the volume fluctuation in the supply chambers 7 and 7 'by the volume fluctuation of the variable volume chamber 8 caused by the cylinder devices 46 and 46'. Therefore, a larger amount of the processed dialysate than the fresh dialysate supplied to the dialyzer 2 from the supply chambers 7 and 7 'by the amount corresponding to the above-mentioned volume fluctuation is collected in the collection chambers 9 and 9'.
Can be collected in the dialysis machine 2
And the amount of ultrafiltration. The above configuration is already known from Japanese Patent Publication No. 6-11314.

In the above construction, the dialyser 2 is supplied with fresh dialysate while producing fresh dialysate in the supply chambers 7 and 7 'of the dialysis containers 3 and 4, and dialyzed, and Are collected in the collection chambers 9 and 9 'and discharged. That is, the control device controls the on-off valves V11, V12, V
13, V14 is closed while on-off valves V1, V2, V3
Are opened, the three-way switching valves V5 and V6 are located at the first switching position, and the three-way switching valves V7 and V8 are located at the second switching position. In this state, water is supplied to the supply chamber 7 of the first dialysate container 3 through the water supply passage 11 by the operation of the pump P1. Thereafter, the on-off valve V2 is closed once to stop the supply of water, the on-off valve V3 is closed to stop the discharge of the treated dialysate from the collection chamber 9, and the on-off valve V13 is opened. , Cylinder device 4
6, the volume of the variable volume chamber 8 is reduced. As a result, a predetermined amount of the liquid A is supplied to the supply chamber 7 through the raw liquid passage 16 and the water supply passage 11. Thereafter, the on-off valve V2,
V3 is opened and the on-off valve V13 is closed. Thereby, water is further supplied to the supply chamber 7 of the first dialysate container 3 via the water supply passage 11. Then, thereafter, the on-off valves V2 and V3 are closed again, the on-off valve 14 is further opened, and the volume of the variable volume chamber 8 is reduced by the cylinder device 46. As a result, a predetermined amount of the B liquid is supplied to the supply chamber 7 via the raw liquid passage 17 and the water supply passage 11. Thereafter, the on-off valves V2 and V3 are opened and the on-off valve V14 is closed to supply water to the supply chamber 7 through the water supply passage 11, and the variable volume chamber 8 moves to the left end in FIG. Continue the water supply until In this manner, fresh dialysate can be produced in the supply chamber 7 of the first dialysate container 3, and the treated dialysate in the collection chamber 9 can be discharged through the discharge passage 47. . Further, in the same manner, fresh dialysate can be produced in the supply chamber 7 'of the second dialysate container 4, and the treated dialysate can be discharged from the recovery chamber 9'. Next, the control device switches the three-way switching valves V5 and V6 to the second switching position. In this state, by operating the pump P2, fresh dialysate in the supply chamber 7 of the first dialysate container 3 is supplied to the dialyzer 2 via the liquid supply passage 12, and the processed dialysate in the dialyzer 2 is processed. The liquid is supplied to the collection chamber 9 of the first dialysate container 3 via the drain passage 13. As a result, the volume of the recovery chamber 9 increases, and accordingly, the pair of diaphragms of the first dialysate container 3 move rightward, and the volume of the supply chamber 7 decreases. Further, at the same time, by reducing the volume of the variable volume chamber 8 by the cylinder device 46, the volume of the recovery chamber 9 is further expanded, and an amount corresponding to the volume fluctuation is removed from the blood in the dialyzer 2 ( Ultrafiltration).

In this manner, fresh dialysate can be supplied from the supply chamber 7 of the first dialysate container 3 to the dialyzer 2 and the treated dialysate can be collected in the collection chamber 9. Similarly, fresh dialysate can be supplied to the dialyzer 2 from the supply chamber 7 'of the second dialysate container 4, and the treated dialysate can be collected in the collection chamber 9'. it can. The above dialysis operation is performed in the first dialysate container 3 and the second dialysate container 4 in the opposite manner, that is, fresh dialysate is supplied to the dialyzer 2 alternately from each of the supply chambers 7 and 7 'and collected. Dialysis can be performed continuously. Next, after the dialysis is performed as described above, it is necessary to clean the inside of each passage and each component constituting the dialysis apparatus 1. Therefore, in this embodiment, A
The cleaning liquid is supplied to the supply chambers 7 and 7 'instead of the liquid and the B liquid, and the cleaning liquid is diluted to a predetermined concentration with water in the supply chambers 7 and 7' by the same process as the dialysis operation described above. Then, the washing liquid supplied to the supply chambers 7 and 7 'is successively circulated from the liquid supply passage 12 into each passage in the same manner as in the above-described dialysis work, and the inside of the circulating passage is washed. The cleaning liquid is circulated in the passage in which the cleaning liquid did not circulate in the cleaning after the switching. That is, first, before the washing operation is started, the end portion 12 a of the liquid supply passage 12 and the end portion 1
3a is removed, the end 12a of the liquid supply passage 12 is connected to one end of the connection plug 14, and the end 13a of the drain passage 13 is connected to the other end of the connection plug 14. The end 16b of the stock solution passage 16 is connected to the branch passage 18 on the side of the washing solution passage 18.
Connected to one end of C
The end 17b of the undiluted liquid passage 17 is connected to the other end of the washing liquid passage 18, and the on-off valve 12 is closed with the on-off valve V11 closed.
The cleaning liquid can be supplied to the undiluted liquid passages 16 and 17 by opening.

In this state, the control device controls the operation of the three-way switching valves V5 to V8 and the on-off valves V2, V3, V13, and V14 in the same manner as in the case of performing the dialysis described above. Thereby, as shown by thick lines in FIGS. 5 and 6, both the stock solution passages 16 and 17 and the water supply passages 11, the supply chambers 7 and 7 ′, the liquid supply passages 12, the connection plugs 14, and the bypass passages on the downstream side thereof The cleaning liquid flows through the drain passage 13, the bypass passage 56, the collection chambers 9, 9 ', and the discharge passage 47, and the insides of these passages and the like are washed. In addition, connection plug 1
The cleaning liquid is caused to flow to the bypass passage 4 and the bypass passage 15 by periodically switching the three-way switching valve V9. As described above, the components of the dialysis apparatus 1 are operated by the control device in the same manner as in the dialysis operation using the cleaning liquid instead of the solution A and the solution B in the dialysis operation, thereby cleaning the inside of each of the above passages and the like. However, if the cleaning is completed at this time, the cleaning liquid does not flow through each of the passages shown by the thick lines in FIG. 7, and the portion is not cleaned. More specifically, the bypass passage 35, the inside of the water supply passage 11 from the on-off valve V1 to the position where the undiluted liquid passage 17 is connected, the two bypass passages 32, 33, and the cleaning liquid passage 18 on the on-off valve V11 side are provided. , The washing liquid will not flow and therefore their interior will not be washed. In particular, the position where the undiluted solution passage 17 is connected from the on-off valve V1 is a portion through which water flows during normal dialysis and needs to be washed.

Therefore, the present embodiment is provided with a washing step for washing the portions which have not been washed conventionally as shown by the thick line in FIG. I have. In this case, the cleaning liquid remaining in one of the supply chambers 7, 7 'and the liquid supply passage 12 at the time of the previous cleaning is used. First, the on-off valve V1 is closed, the on-off valve V10 is opened, and the pump P2 is stopped, so that the water supply passage 11 is supplied from the supply chamber 7 (7 ') via the bypass passage 35.
A flow path for the cleaning liquid to the cleaning liquid is formed. However, even if the pump P1 is operated in this state, if the operation is the same as the dialysis operation, the cleaning liquid does not flow into the recovery chamber 9 (9 '), so that the pressure in the recovery chamber 9 (9') becomes negative. The balance between the volumes of the collection chamber 9 (9 ') and the supply chamber 7 (7') is lost, and the supply of the cleaning liquid from the supply chamber 7 (7 ') stops. Therefore, as shown in FIG. 1, the control device positions the three-way switching valve V5 at the first switching position and positions the three-way switching valve V6 at the first switching position.
With the three-way switching valve V7 located at the second switching position, the three-way switching valve V8 is located at the first switching position, that is, the collection chamber 9 is disposed via the discharge passage 47 between the three-way switching valves V6 and V8. In a state in which a communication path that allows the and the recovery chamber 9 'to communicate with each other is formed, the on-off valve V3 is closed and the pump P1 is operated. Thus, the flow path of the cleaning liquid shown in FIG. 1 is formed, and the cleaning liquid can flow inside the flow path. That is, the water remaining in the water supply passage 11 and the bypass passage 35 and the subsequent washing liquid are supplied to the supply chamber 7 of the first dialysate container 3 by the pump P1, and the inside of the supply chamber 7 has its maximum volume. To expand. In this process, since the two three-way switching valves V6 and V8 communicate with each other through the discharge passage 47, the volume of the recovery chamber 9 is reduced in conjunction with the expansion of the supply chamber 7 of the first dialysate container 3. And the second
The volume of the recovery chamber 9 'of the dialysate container 4 is increased, and at the same time, the supply chamber 7' of the second dialysate container 4 is reduced from the maximum volume to the minimum volume, and remains inside it by the previous washing operation. The cleaning liquid that has passed through the liquid supply passage 12
The water is sent out to the water supply passage 11. When the supply chamber 7 of the first dialysate container 3 is expanded to the maximum limit, the detection result of the flow rate by the flow rate sensor 37 becomes zero.
As shown in (5), the three-way switching valve V5 is switched to the second switching position, and the three-way switching valve V7 is switched to the first switching position. Then, the flow path of the cleaning liquid indicated by the thick line in FIG. 2 is formed. Then, the cleaning liquid in the water supply passage 11 and the bypass passage 35 is supplied to the supply chamber 7 'of the second dialysate container 4 by the pump P1, and the supply chamber 7'
Inside expands to its maximum volume. Two-way switching valve V
6 and V8 communicate with each other through the discharge passage 47, so that the volume of the recovery chamber 9 'is reduced in conjunction with the expansion of the supply chamber 7' of the second dialysate container 4, and the first dialysate is discharged. The volume of the collection chamber 9 of the container 3 increases, and at the same time, the first dialysate container 3
Of the supply chamber 7 is reduced from the maximum volume to the minimum volume, and the cleaning liquid in the supply chamber 7 is sent out to the bypass passage 35 and the water supply passage 11 via the liquid supply passage 12.

Thus, the bypass passage 35 and the water supply passage 11 from the place where the bypass passage 35 is connected to the supply chambers 7 and 7 'are provided.
, Both bypass passages 32 and 33 are cleaned by the cleaning liquid. When the detection result of the flow rate by the flow rate sensor 37 becomes zero, the control device switches the three-way switching valve V5 to the first switching position and switches the three-way switching valve V7 to the second switching position as shown in FIG. On-off valve V2
, While the on-off valves V11 and V14 are opened.
As a result, a flow path of the cleaning liquid indicated by a thick line in FIG. 3 is formed. Next, the flow sensor 37
When the detection result of the flow rate becomes zero, the control device switches the three-way switching valve V5 to the second switching position, switches the three-way switching valve V7 to the first switching position, and switches the on-off valve V1.
4 is closed and the on-off valve V13 is opened, so that another flow path for the washing liquid is formed as shown in FIG. Thereby, the bypass passage 35, the water supply passage 11 and the washing passage 18 from the place where the bypass passage 35 is connected, and the stock solution passage 1
6, 17, the two bypass passages 32, 33 are cleaned by the cleaning liquid. Further, by repeatedly switching the three-way switching valves V5 and V7, the cleaning liquid is alternately supplied to and discharged from the supply chambers 7 and 7 ', whereby the cleaning liquid circulates in the flow path of the cleaning liquid. It is.

In this embodiment, through the above steps,
The inside of each passage and the like constituting the dialysis apparatus 1 is washed by circulating a washing liquid. In other words, in the present embodiment, by using the bypass passage 35 used in the dialysis preparation operation, the flow path of the cleaning liquid shown in FIGS. 1 to 4 is configured to flow the cleaning liquid therethrough. I have. Therefore, the water supply passage 1 in which the cleaning liquid has not been circulated until now.
1 and the bypass passage 35 and the washing passage 18 can be washed. In addition, in these newly provided cleaning steps, the cleaning liquid remaining in the supply chamber and the liquid supply passage in the conventional cleaning step performed earlier is used, and the amount of the cleaning liquid used is the same as that of the conventional cleaning step. does not change. Furthermore, since the cleaning liquid is circulated without passing through the recovery chamber that has already been cleaned, the cleaning time is reduced as compared with the case where the discharge passage and the water supply passage are connected and circulated in the same process as the dialysis operation. . In the above embodiment, each of the first dialysate container 3 and the second dialysate container 4 as the processing means has a supply chamber 7 (7 ') and a recovery chamber 9 (9') in a single container. In this case, the present invention is applied, but a supply chamber is formed in one of a pair of independent left and right containers as disclosed in FIG. 5 of Japanese Patent Publication No. 3-62107, and a collection chamber is formed in the other. The present invention can also be applied to a dialysis apparatus provided with two processing means as described above.

[0020]

As described above, according to the present invention, the effect that the inside of the water supply passage, which could not be cleaned by the conventional method, can be cleaned with the cleaning liquid can be obtained.

[Brief description of the drawings]

FIG. 1 is a configuration diagram showing one process at the time of cleaning in one embodiment of the present invention.

FIG. 2 is a configuration diagram showing one process at the time of cleaning in one embodiment of the present invention.

FIG. 3 is a configuration diagram showing one process at the time of cleaning in one embodiment of the present invention.

FIG. 4 is a configuration diagram showing one process at the time of cleaning in one embodiment of the present invention.

FIG. 5 shows a state during cleaning in a conventional method for cleaning a dialysis device.
The block diagram which shows a process.

FIG. 6 shows a state during cleaning in a conventional method for cleaning a dialysis device.
The block diagram which shows a process.

FIG. 7 is a configuration diagram showing a portion that could not be cleaned by a conventional method for cleaning a dialysis device.

[Explanation of symbols]

 Reference Signs List 1 dialyzer 2 dialyzer 3 first dialysate container (first processing means) 4 second dialysate container (second processing means) 7, 7 'supply chamber 9, 9' collection chamber 11 water supply passage 12 supply passage 13 drain passage 35 bypass passage 47 discharge passage V1 on-off valve P1 pump

 ──────────────────────────────────────────────────続 き Continued on the front page F term (reference) 3B116 AA13 AA47 AB51 BB03 CD22 CD41 4C077 AA05 BB01 CC02 DD02 DD14 DD17 DD26 DD27 EE03 GG13 KK09

Claims (1)

[Claims] 1. A first processing means comprising a supply chamber and a recovery chamber for supplying and recovering dialysate to a dialyzer, and a second processing means comprising a supply chamber and a recovery chamber for supplying and recovering dialysate to a dialyzer. Means, a water supply passage connected to the supply chambers of the first treatment means and the second treatment means, and supplying water for producing fresh dialysate from a supply source, and a water supply passage provided in the water supply passage. A pump for supplying water of the source to each of the supply chambers, an on-off valve provided between the pump and the supply source in the water supply passage to open and close the water supply passage, the first processing means and the second processing A fresh dialysis fluid supply passage for communicating each supply chamber of the means with the dialyzer, and a treated dialysis fluid drain passage for communicating the dialyzer with the collection chambers of the first processing means and the second processing means; Connected to the collection chambers of the first processing means and the second processing means. And a discharge passage for discharging the treated dialysate in the collection chamber to the outside. The end of the supply passage connected to the dialyzer and the end of the discharge passage connected to the dialyzer are connected to each other. In a state where the cleaning liquid is supplied to the supply chambers of the two processing means, the cleaning liquid is sequentially circulated from the liquid supply passage, and the dialysis device is cleaned in the flow path. A bypass passage communicating between the water supply passage located between the pumps and the liquid supply passage or the drainage passage,
A communication path for communicating the collection chambers of the first processing means and the second processing means with each other; closing the on-off valve when required, and supplying a water supply passage between the on-off valve and the pump by a bypass passage; The pump is operated in a state where the liquid passage or the drain passage is communicated, and the collection chambers of the first processing means and the second processing means are communicated with each other through the communication path, and the pump is operated from the supply chamber to the water supply passage. A method for cleaning a dialysis device, comprising a cleaning step of circulating a cleaning liquid to clean the inside thereof.