JP2001001389A - Container for liquid agent and production of stretch blow molded bottle for liquid agent - Google Patents

Abstract

PROBLEM TO BE SOLVED: To prevent the deterioration of the appearance of a bottle caused by the generation of the non-uniform peeled part between the inner and outer layers of the bottle while employing a laminated bottle in order to suppress the reduction in the transmission amt. of steam and the adsorption of a medicinal component. SOLUTION: A container comprises a bottle 4 having a body portion and a mouth portion 2 and the cap 6 attached to the mouth portion 2 of the bottle 3 in a freely detachable manner. The bottle 4 is formed by laminating inner and outer synthetic resin layers 8 made of different materials and the inner and outer synthetic resin layers 8, 9 of the body portion 3 of the bottle are preliminarily peeled over the entire periphery of the body portion in a production line.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a container for a liquid preparation which can be suitably used as a container for eye drops, and a method for producing a bottle which is a main component of the container by a stretch blow molding method. .

[0002]

2. Description of the Related Art As a bottle for a drug solution such as an eye drop, for example, a stretch blow-molded product made of a high-molecular synthetic resin material has been widely used, and an injection-molded bottle has also been used. In particular, since chemical solutions such as eye drops are applied to the human body, sufficient water vapor barrier properties and gas barrier properties are required so that the liquid properties do not change as much as possible during long-term storage, and sufficient consideration is given to material selection. I have.

[0003] For example, molding materials for bottles for eye drops include PP, LDPE, HDPE and COP (Circle Ole).
Transparent olefin materials such as fin Polymer) have been used. Olefin-based materials are high in chemical resistance and excellent in water vapor barrier properties. Therefore, in the field of chemical liquid containers as described above, they are preferable materials from the viewpoint of preventing a change in a medicinal component due to loss of water vapor transmission. further,
Since the olefin-based material is a relatively flexible material, there is little restriction on the bottle shape, and sufficient squeezability (compression deformation by pressing) can be obtained even when the olefin-based material is molded into a simple bottomed cylindrical bottle shape. If the bottle has a bottomed cylindrical shape, a bottle transport path with guide rails can be formed in the production line where the bottle is filled with a chemical solution after blow molding. It has the advantage that it can be built.

[0004]

However, some of the medicinal components and preservatives are adsorbed, absorbed, or sorbed by the olefin resin material. Such medicinal ingredients include, for example, vitamin E (PL-α-tocopherol) and the like.
-Phenylethyl alcohol (β-PEA), benzalkonium chloride (BKC) and the like. As a container for such a drug containing a medicinal ingredient or a preservative, a polyester-based transparent resin material to which the medicinal ingredient or the preservative is not adsorbed is used. Since polyester-based resins such as PET and PEN have relatively high water vapor permeability, pillow packaging or the like is applied to prevent a change in a medicinal component due to a decrease in water vapor transmission. On the other hand, there are also agents that dislike contact with polyester. In this case, a polyolefin-based material is used. However, since the O ₂ barrier function is insufficient, pillow packaging and an oxygen absorber are also used in this case. Is done.

[0005] Since the polyester-based material is a relatively hard material, it must be designed in a bottle shape having a flat cross section in order to provide a certain degree of water vapor barrier property and gas barrier property while providing the necessary squeezing properties as an eye drop bottle. Inevitably, the production line needs to be remodeled significantly in accordance with the change in the shape of the container. Therefore, in order to use an existing production line, the fact is that the chemicals that can be produced as a result are limited.

SUMMARY OF THE INVENTION The present invention provides a liquid container capable of using a production line having a high degree of freedom in mass production while increasing the degree of freedom of the bottle shape while reducing both the adsorptivity of the medicinal component and the water vapor permeability. Another object of the present invention is to provide a method for producing a stretch blow-molded bottle.

[0007]

In order to achieve the above object, the present applicant has a bottle having a body and a mouth, and a cap detachably attached to the mouth of the bottle. We have invented a liquid container in which a bottle is formed by laminating synthetic resin layers of different materials inside and outside. According to this, for example, the resin material forming the inner synthetic resin layer of the wall portion of the bottle body is a saturated polyester having a low adsorptivity of a medicinal component, while the resin material forming the outer synthetic resin layer has water vapor. By using a polyolefin with high barrier properties, the drawbacks of both can be mutually covered, a low-absorbency of the medicinal component and a container for a medicinal solution with a high water vapor barrier property can be provided, and the medicinal component changes even after long-term storage. Can be prevented. Further, since the saturated polyester of the inner synthetic resin layer only has to function as a protective layer for the medicinal component, the relatively hard saturated polyester layer can be made as thin as possible to easily obtain a desired squeezing property, Since the degree of freedom in shape design is increased and the bottle can be configured as a cylindrical bottle with a bottom, a production line with high mass productivity can be used, and mass productivity and cost reduction can be achieved.

Although the liquid medicine container using the above-mentioned laminated bottle has the above-mentioned advantages, the experiment by the inventor of the present application has revealed that the following problem occurs according to the above-mentioned laminated bottle. did. That is, immediately after the bottle is molded, the inner synthetic resin layer and the outer synthetic resin layer are in close contact with each other due to the adhesiveness of these constituent resin materials, but the saturated polyester of the inner synthetic resin layer is The inner synthetic resin layer and the outer synthetic resin layer are partially peeled off due to the pressure of water vapor passing through the inner synthetic resin layer because the water vapor permeability is higher than the polyolefin of the layer, and the wall of the bottle body In the form of a bubble. When such a phenomenon occurs, the bottle is often discarded for safety even if there is no deterioration in quality as a medicine due to deterioration of its appearance, and it is necessary to improve the bottle structure and the like.

[0009] It is considered that the formation of a bubble-like exfoliated portion at the interface between the inner synthetic resin layer and the outer synthetic resin layer in the above-mentioned laminated bottle is due to the low adhesiveness of the polyolefin. In order to prevent the appearance of a bubble-like pattern, the inner synthetic resin layer and the outer synthetic resin layer must be separated from each other in advance, or the adhesive strength between the inner synthetic resin layer and the outer synthetic resin layer. Should be strengthened.

[0010] The solution container of the present invention based on such knowledge is provided with a bottle having a body and a mouth, and a cap detachably attached to the mouth of the bottle. A synthetic resin layer is formed by laminating the inner and outer layers, wherein the inner synthetic resin layer and the outer synthetic resin layer of the bottle body have no mutual adhesiveness. According to this, immediately after the bottle is molded, the inner synthetic resin layer and the outer synthetic resin layer adhere to each other due to a bonding force between molecules generated by thermoforming. The layer and the outer synthetic resin layer are peeled off in advance so that their mutual adhesiveness is eliminated, so that even when stored for a long period of time, a bubble-like pattern does not appear on the body, and a good appearance is maintained. Can be. The inner synthetic resin layer and the outer synthetic resin layer may be peeled off at the mouth and the bottom of the bottle in advance, but the inner synthetic resin layer and the outer synthetic resin layer are prevented from relatively rotating. To this end, it is preferable to bond the inner synthetic resin layer and the outer synthetic resin layer at the mouth and bottom of the bottle, which do not significantly affect the appearance.

The liquid medicine container of the present invention comprises a bottle having a body and a mouth, and a cap detachably attached to the mouth of the bottle, wherein the bottle is made of a synthetic resin of a different material. An additive material which is formed by laminating the inside and outside, and which enhances the adhesiveness between the inner synthetic resin layer and the outer synthetic resin layer of the wall of the bottle body, comprises synthetic resin and / or Alternatively, it is mixed in the synthetic resin constituting the outer synthetic resin layer. According to this, since the adhesive force between the inner synthetic resin layer and the outer synthetic resin layer of the bottle is increased by mixing the additive materials, the inner synthetic resin layer and the outer synthetic resin layer are less likely to be separated, and The appearance of a bubble-like pattern is prevented.

The laminated bottle can be molded by an appropriate molding method such as an injection molding method, a direct blow molding method, or an injection blow molding method.
In consideration of cost, it is preferable to form by stretch blow molding using a laminated parison in which different kinds of synthetic resins are laminated inside and outside.

In each of the above liquid agent containers, the inner and outer synthetic resin layers can be fitted to each other at the mouth of the bottle. For example, using an injection molding machine, first, a PET parison having a vertical rib and a horizontal rib on the outer periphery of the mouth is molded, and this PET parison is inserted into another injection molding die, and the outer periphery is formed of PP. Are laminated by injection molding, whereby a structure is obtained in which the PET of the inner synthetic resin layer and the PP of the outer synthetic resin layer are fitted into the mouth in an uneven manner. According to this, when the inner synthetic resin layer and the outer synthetic resin layer are separated in advance at the bottle body, a strong bond is obtained between the inner synthetic resin layer and the outer synthetic resin layer at the mouth. Even in the case of a cylindrical bottle, the inner synthetic resin layer and the outer synthetic resin layer do not relatively rotate, and the operability of the cap screwed to the bottle mouth is improved, and the cap is The airtightness at the time of mounting is improved. In addition, in the case where the adhesiveness between the inner synthetic resin layer and the outer synthetic resin layer of the bottle is increased, a strong connection between the inner synthetic resin layer and the outer synthetic resin layer can be obtained at the mouth, so that the cap is repeatedly attached and detached. Even if it is performed, it is possible to prevent stress from acting on the interface between the inner synthetic resin layer and the outer synthetic resin layer of the bottle body, and prevent them from peeling off.

The present invention is suitably carried out when the bottle is a cylindrical ophthalmic bottle having a bottom and a squeezing property on its body. Further, a saturated polyester such as PET (polyethylene terephthalate) or PEN (polyethylene naphthalate) is used for the inner synthetic resin layer material of the bottle, and PP (polypropylene), PE (polyethylene) or COP ( Circle Olefi
It is preferable to use a polyolefin such as n Polymer). Conversely, when polyolefin is used for the inner synthetic resin layer material of the bottle and saturated polyester is used for the outer synthetic resin layer material, the oxygen barrier function is ensured and the effect of preventing the diffusion of gas components such as content flavoring agents is improved. In this case, it is also possible to prevent bubbles from being generated between the inner and outer layers.

In the above-mentioned liquid container, in order to further reduce the water vapor transmission loss, the cap is attached to the mouth so as to cover the outer peripheral side of the mouth of the bottle, and the lower edge of the cap has a lower peripheral edge. The structure can be in airtight contact with the outer surface of the bottle. According to this, a flange portion extending outward is formed at the upper end (opening end) of the inner synthetic resin layer due to the structure of the molding machine and the necessity of the molding step, and the outer synthetic resin layer is formed below the flange portion. In such a case that a laminate is formed, a small amount of water vapor may leak into the space between the cap and the bottle mouth via the flange portion of the inner synthetic resin layer having relatively high water vapor permeability. However, by keeping the lower peripheral edge of the cap in airtight contact with the outer surface of the bottle, water vapor can be prevented from leaking out of the cap, and water vapor leakage from the lower end of the cap during long-term storage can be eliminated. In addition, as a constituent material of the cap,
Of course, it is preferable to use a material having a high water vapor barrier property (eg, polyolefin, metal, etc.).

The bottle in which the inner synthetic resin layer and the outer synthetic resin layer have been peeled in advance can be manufactured by the following method. That is, the method for producing a stretch blow-molded bottle of the present invention comprises the steps of producing a laminated parison by laminating different synthetic resins inside and outside, and stretching and blow molding the laminated parison in a blow mold to form a trunk and a mouth. And a step of separating the inner synthetic resin layer and the outer synthetic resin layer of the wall of the bottle body from each other. In the production of the laminated parison, the inner synthetic resin layer and the outer synthetic resin layer may be injection-molded using different injection molding dies, respectively, or may be formed by a two-layer extruder, and other suitable It can be manufactured by means of

In the above manufacturing method, preferably, the inner synthetic resin layer material is a saturated polyester and the outer synthetic resin layer material is a polyolefin. In addition, the inner synthetic resin layer and the outer synthetic resin layer can be peeled off by pressing the bottle body from the outer peripheral side to be elastically deformed, and can be peeled off by other appropriate means.

In another aspect of the present invention, there is provided a method for producing a stretch blow-molded bottle, comprising a step of laminating an inner synthetic resin layer made of a saturated polyester and an outer synthetic resin layer made of a polyolefin mixed with an α-olefin. The method includes a step of manufacturing a parison and a step of forming a bottle having a body and a mouth by stretch-blowing the laminated parison in a blow mold. According to this, since the α-olefin that increases the adhesiveness is added to and mixed with the polyolefin, good adhesiveness is obtained between the inner synthetic resin layer and the outer synthetic resin layer after blow molding,
The appearance of a bubble-like pattern is prevented.

[0019]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The embodiments of the present invention will be described below with reference to the drawings.

[First Embodiment] FIG. 1 schematically shows an ophthalmic solution container 1 which is a container for a liquid agent according to a first embodiment of the present invention. And a bottle 4 having a body 3, a nozzle 5 attached to the mouth 2 of the bottle 4, and a cap 6 detachably attached to the mouth 2.

The bottle 4 is a cylindrical ophthalmic bottle with a bottom having a squeezing property. Therefore,
The cap 4 is removed from the mouth 2 and the bottle 4 is turned upside down. The body 3 is elastically deformed inward in the radial direction by pressing the body 3 with a finger or the like from the outer peripheral side.
It is possible to instill the drug solution inside. In addition, bottle 4
The opening 2 has an opening on the upper side, and a helical screw portion 7 for attaching a cap is provided on the outer periphery.

The bottle 4 is formed by laminating synthetic resin layers 8, 9 of different materials inside and outside. Such a laminated bottle 4 can be formed using a conventionally known appropriate method such as an injection molding method, a direct blow molding method, or an injection blow molding method. A characteristic part of the bottle 4 according to the present embodiment is that the inner synthetic resin layer 8 and the outer synthetic resin layer 9 of the bottle body 3 are peeled over the entire circumference. That is, when the bottle 4 having the inner and outer synthetic resin layers 8 and 9 is formed by injection molding or stretch blow molding, the resin is heated to the extent that the resin is plasticized during molding. Shows adhesiveness. In the present embodiment, after the bottle is cooled and solidified, the inner layer 8 and the outer layer 9 of the bottle body 3 are separated by an appropriate means.

Such peeling can be performed, for example, by disposing a rubber roller 10 in the middle of the production line as shown in FIG. 2, and pressing the bottle body 3 from the outside in the radial direction by the roller 10. . In the illustrated example, a plurality of pressing rollers 10 are disposed in the conveying direction on both sides in the width direction of the guide rail 11 in the middle of the production line, and each of the rollers 10 is driven to rotate. Are configured so that the peripheral wall of the body 3 can be compressed and deformed radially inward while rotating the bottle 4. The present invention is not limited to such a peeling method, and the inner layer 8 and the outer layer 9 can be peeled by an appropriate method. Since the adhesion between the inner layer 8 and the outer layer 9 immediately after the bottle molding is due to the weak bonding force between the molecules constituting these layers, the layers 8 and 9 come into contact with each other after the above-described peeling step. And there is no adhesion between them.

As a constituent material of the inner synthetic resin layer 8, a polyester synthetic resin material can be used. Polyester is a polymer material synthesized by condensation polymerization. Condensation polymerization is a sequential polymerization reaction in which low molecules such as water and alcohol are removed from two molecules in a high-temperature, vacuum atmosphere, and the molecular weight gradually increases. Since this polyester has a polar group called an ester bond, Van der Waals force acting between molecules is strong, and is generally known as a relatively hard polymer material. As polyester-based synthetic resin materials, saturated polyesters such as PET (polyethylene terephthalate) and PEN (polyethylene naphthalate) are known in addition to polyester.

PET has the properties of being colorless, transparent, glossy, odorless, and excellent in gas barrier properties. When PET is used for the inner layer 8 of the injection blow-molded bottle, for example, solid-state polymerized PET resin having an IV of 0.8 or more can be used as a raw material. This P
Injection molding of a bottomed cylindrical parison using ET resin,
An outer synthetic resin layer 9 to be described later is provided on the outer peripheral side of the PET parison.
Are laminated to produce a laminated parison 12 shown in FIG. 3, and the laminated parison 12 is inserted into a blow mold (not shown) and stretch blow-molded to obtain the laminated bottle 4 described above. It is.

Inner layer 8 of direct blow molded laminated bottle
When PET is used, the viscosity of the molten PET resin must be high in order to extrude it into a tube,
Since the bottle is not stretched, the physical properties of PET itself must be high. For this reason, a solid-state polymerized PET resin having an IV of 1.0 or more is usually used for compact direct blow bottle molding.

PEN (polyethylene naphthalate) is
It is a polyester obtained by condensation polymerization of 2,6 naphthalene dicarboxylic acid and ethylene glycol. This PEN
Also have relatively high heat resistance, gas barrier properties, and strength, and can be handled almost in the same manner as PET.

As the constituent material of the outer synthetic resin layer 9, an olefin-based synthetic resin material can be used. Preferably, a polyolefin such as PP (polypropylene), PE (polyethylene) or COP (Circle Orefin Polymer) is used. .

PE is roughly classified into LDPE (low-density polyethylene) and HDPE (high-density polyethylene), and any of these can be used as the bottle constituting material of the present invention.

Returning to the description of the bottle structure, the inner synthetic resin layer 8 and the outer synthetic resin layer 9 in the bottle mouth portion 2 are fitted to each other so as to regulate relative movement in the axial and circumferential directions of the bottle. are doing. More specifically, as shown in FIGS. 4 to 6, a pair of upper and lower flange-like horizontal ribs 13 are formed on the outer periphery of the mouth of the inner layer 8 over the entire circumference in the circumferential direction. A plurality of vertical ribs 14 are formed at intervals in the circumferential direction. By injection molding the outer layer 9 on the outer surface side of the inner layer 8, the inner and outer layers 8,
Nine uneven fittings can be obtained. When the bottle 4 is molded by the blow molding method, as shown in FIG. 3, the laminated parison 12 is molded by the injection molding method, and the mouth portion 2 is attached to a lip mold (not shown) to blow mold. The parison 12 is inserted into the mold and stretch blow molded.
In the illustrated embodiment, an outwardly extending flange portion 8a is formed at the upper end of the inner layer 8 due to the mold structure, and an outer layer 9 is laminated below the flange portion 8a.

Further, in an embodiment in which the bottle 4 is manufactured by the injection blow molding method, for example, first, a PET preform constituting the inner layer 8 is molded and stocked by using an injection molding machine. The PET preform is inserted into another mold, and PP constituting the outer layer 9 is injection-molded on the outer surface of the preform to obtain a laminated parison 12.
The laminated parison 12 is heated and blown using a cold parison stretch blow molding machine to form a bottle 4 having the above structure.
Can be obtained. The injection molding step is a step of molding a cold parison. However, two injection molding machines may be used, or a two-color molding machine may be used. It is also possible to use a molding machine that performs this. In the manufacturing method of this embodiment, even if the parison is heated only by external heating before blow molding, it is possible to perform stable blow molding by supporting the PET of the inner layer with PP. In general, PP rather than PET
In the method (1), the blow temperature is high, and a cold parison of PP cannot be stably blow-molded due to drawdown or deformation. However, good blow-molding can be performed by using a laminated parison.

The nozzle 5 has a substantially cylindrical shape as a whole, and is provided with a flange portion 5a which comes into contact with the inner-layer flange portion 8a at an intermediate portion in the vertical direction. The portion below the flange portion 5a has a slightly tapered cylindrical shape, and is inserted into the opening of the bottle inner layer 8. This nozzle 5
Although various materials can be used as the constituent material, those having high water vapor barrier properties, gas barrier properties, and chemical resistance are preferable. For example, polyolefin can be used.

The cap 6 is attached to the mouth 2 so as to cover the outer peripheral side and the upper portion of the bottle mouth 2, and has a peripheral wall 6a and a canopy 6b. Surrounding wall 6a
On the inner surface, a protrusion 15 that engages with the screw portion 7 of the mouth portion 2 is provided at an appropriate location, and the cap 6 is attached and detached by rotating the cap 6 relative to the mouth portion 2. . On the inner surface of the canopy portion 6b, a concave portion 16 for sealing the opening at the tip of the nozzle 5 is provided.
By screwing the nozzle 5 into the nozzle 5, the tip of the nozzle 5 is brought into close contact with the recess 16 so that leakage of the chemical solution from the opening of the tip of the nozzle 5 and permeation of water vapor can be prevented.

Further, when the cap 6 is attached to the mouth 2, that is, when the tip of the nozzle 5 is brought into close contact with the recess 16, the lower peripheral edge of the cap 6 is simultaneously attached to the outer surface of the bottle 4 (in the illustrated example). , The shoulder of the bottle 4). According to this, even if a very small amount of water vapor permeates from the flange portion 8 a of the inner layer 8, the water vapor is prevented from leaking outward from the lower end of the cap 6 by contact between the cap 6 and the bottle 4. By saturating water vapor in the space inside the cap 6, further reduction in water vapor transmission can be prevented, and the long-term storage property can be further improved.

[Second Embodiment] Hereinafter, a second embodiment of the present invention will be described. However, since most of the structure is the same as that of the first embodiment, the same reference numerals are given and the detailed description is omitted.
The different configurations, functions and effects will be described.

In the first embodiment, after the bottle 4 is formed, the inner layer 8 and the outer layer 9 are peeled off at the bottle body before filling with the liquid agent (chemical solution). It is also possible to improve the adhesiveness of these layers without peeling off both layers 8 and 9. The liquid medicine container according to the present embodiment includes a bottle 4 having a body 3 and a mouth 2.
And a cap 6 detachably attached to the mouth 2 of the bottle 4. The bottle 4 is formed by laminating synthetic resin layers 8, 9 of different materials inside and outside. An additive material for improving the adhesiveness between the inner synthetic resin layer 8 and the outer synthetic resin layer 9 of the part 3 is mixed with the synthetic resin forming the inner synthetic resin layer 8 and / or the synthetic resin forming the outer synthetic resin layer 9. Is what is being done.

The additive material is appropriately selected according to the synthetic resin material constituting the inner layer 8 and the outer layer 9. For example, when a saturated polyester is used as the inner synthetic resin material and a polyolefin is used as the outer synthetic resin material, a material obtained by adding and mixing a small amount of an α-olefin (for example, 1-hexane or the like) to the polyolefin is used. Layer 9
Is formed on the outer peripheral side of the inner synthetic resin layer 8 by injection molding. Thereby, the adhesiveness between the inner layer 8 and the outer layer 9 is improved, and the separation between the inner layer 8 and the outer layer 9 is prevented.

As a method for producing such a bottle 4 by stretch blow molding, for example, a method of laminating an inner synthetic resin layer made of a saturated polyester and an outer synthetic resin layer made of a polyolefin mixed with an α-olefin is used. The method includes a step of manufacturing a parison by an injection molding method, and a step of forming a bottle having a body and a mouth by stretch-blowing the laminated parison in a blow mold. Needless to say, the bottle 4 can be manufactured by another appropriate method. The present invention is not limited to the above embodiments, and it is needless to say that the design can be appropriately changed. For example, when a polyolefin is used as the inner layer material and a saturated polyester is used as the outer layer material, it can be suitably used as a container for a liquid agent which dislikes contact with the polyester, and has an improved oxygen barrier property and a content flavoring agent. It is possible to prevent the diffusion of gas components such as.

[0039]

According to the liquid medicine container of the present invention, since a laminated bottle in which synthetic resin materials of different materials are laminated inside and outside is used, reduction of adsorption of a medicinal component, elimination of loss of water vapor transmission, etc. can be achieved at once. In addition, no bubbles are generated between the inner and outer layers of the bottle even after long-term storage, and even when the outer layer has a higher water vapor barrier property, the occurrence of a bubble-like peeling phenomenon in the body is eliminated.

[Brief description of the drawings]

FIG. 1 is a semi-longitudinal cross-sectional front view of a liquid agent container according to an embodiment of the present invention.

FIG. 2 is a simplified plan view in the middle of a production line, showing a method of separating an inner synthetic resin layer and an outer synthetic resin layer of a bottle of the liquid agent container.

FIG. 3 is a longitudinal sectional view of a laminated parison when the bottle is manufactured by a stretch blow molding method.

FIG. 4 is an enlarged perspective view showing a mouth structure of an inner layer synthetic resin of the laminated parison.

FIG. 5 shows a mouth portion and a cap mounting structure of the liquid agent container, wherein the left half is a vertical sectional front view of a portion where no vertical rib is present, and the right half is a front view showing only the cap in cross section.

FIG. 6 is a longitudinal sectional view of a portion where a vertical rib exists, showing a mouth portion and a cap mounting structure of the liquid agent container.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Liquid container (eyedrop container) 2 Mouth 3 Body 4 Bottle (Eyedrop bottle) 5 Nozzle 6 Cap 8 Inner synthetic resin layer 9 Outer synthetic resin layer 12 Laminated parison 13 Horizontal rib 14 Vertical rib

Claims (10)

[Claims] A bottle (4) having a body (3) and a mouth (2), and a cap (6) detachably attached to the mouth (2) of the bottle (4), The bottle (4) is formed by laminating synthetic resin layers (8, 9) of different materials inside and outside, and the inner synthetic resin layer (8) and the outer synthetic resin of the bottle body (3). A container for a liquid agent, which has no mutual adhesiveness with the layer (9). 2. A bottle (4) having a body (3) and a mouth (2), and a cap (6) detachably attached to the mouth (2) of the bottle (4), The bottle (4) is formed by laminating synthetic resin layers (8, 9) of different materials inside and outside, and the inner synthetic resin layer (8) and the outer synthetic resin of the bottle body (3). An additive material for improving the adhesiveness with the layer (9) is mixed in the synthetic resin constituting the inner synthetic resin layer (8) and / or the synthetic resin constituting the outer synthetic resin layer (9). Liquid container. 3. A method according to claim 1, wherein the inner and outer synthetic resin layers (8, 9) are fitted into the bottle mouth (2) so as to restrict relative movement in the axial direction and the circumferential direction of the bottle. Item 3. The liquid container according to Item 1 or 2. 4. The liquid container according to claim 1, wherein the bottle (4) is a cylindrical ophthalmic bottle with a bottom having a squeezing property. 5. The bottle according to claim 1, wherein the material of the inner synthetic resin layer (8) of the bottle (4) is a saturated polyester and the material of the outer synthetic resin layer (9) is a polyolefin. A container for a liquid agent according to the above item. 6. The bottle according to claim 1, wherein the material of the inner synthetic resin layer of the bottle is polyolefin and the material of the outer synthetic resin layer is a saturated polyester. A container for a liquid agent according to the above item. 7. A cap (6) is attached to the mouth (2) so as to cover an outer peripheral side of the bottle mouth (2), and a lower peripheral edge of the cap (6) is attached to an outer surface of the bottle (4). The liquid container according to claim 5, wherein the container is in airtight contact with the container. 8. A process for producing a laminated parison (12) comprising different synthetic resins laminated inside and outside, and stretching and blow molding the laminated parison (12) in a blow mold to form a body (3) and a mouth. A step of molding a bottle (4) having a portion (2) and a step of peeling off the inner synthetic resin layer (8) and the outer synthetic resin layer (9) of the wall of the bottle body (3). A method for producing a stretch blow-molded bottle for a liquid agent, comprising: 9. The separation between the inner synthetic resin layer (8) and the outer synthetic resin layer (9), wherein the material of the inner synthetic resin layer (8) is a saturated polyester and the material of the outer synthetic resin layer (9) is a polyolefin. 9. The method for producing a stretch blow-molded bottle for a liquid agent according to claim 8, wherein the step (b) is performed by pressing the bottle body (3) from the outer peripheral side to elastically deform the bottle body. 10. A process for producing a laminated parison (12) in which an inner synthetic resin layer (8) made of a saturated polyester and an outer synthetic resin layer (9) made of a polyolefin mixed with an α-olefin are stacked. And a step of stretch-blowing the laminated parison (12) in a blow mold to form a bottle (4) having a body (3) and a mouth (2). For manufacturing stretch blow-molded bottles.