|
US5932579A
(en)
|
1996-06-18 |
1999-08-03 |
Affymax Technologies N.V. |
Collagenase-1 and stromelysin-1 inhibitors, pharmaceutical compositions comprising same and methods of their use
|
|
US5830869A
(en)
*
|
1996-06-21 |
1998-11-03 |
Mitchell; Mark Allen |
Thiadiazole amide MMP inhibitors
|
|
EP0929519B1
(en)
*
|
1996-09-27 |
2005-02-23 |
PHARMACIA & UPJOHN COMPANY |
Beta-sulfonyl hydroxamic acids as matrix metalloproteinases inhibitors
|
|
GB9702088D0
(en)
|
1997-01-31 |
1997-03-19 |
Pharmacia & Upjohn Spa |
Matrix metalloproteinase inhibitors
|
|
WO1998039326A1
(en)
*
|
1997-03-04 |
1998-09-11 |
Monsanto Company |
Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds
|
|
US6566373B2
(en)
|
1997-05-06 |
2003-05-20 |
Smithkline Beecham Corporation |
Protease inhibitors
|
|
AR013079A1
(es)
*
|
1997-05-06 |
2000-12-13 |
Smithkline Beecham Corp |
Derivados sustituidos de tetrahidrofurano-3-onas, de tetrahidropirano-3- onas y tetrahidrotiofen-3-onas, un procedimiento para su preparacion unacomposicion farmaceutica de un medicamento util como inhibidores de proteasas e intermediarios
|
|
US5883131A
(en)
*
|
1997-07-09 |
1999-03-16 |
Pfizer Inc. |
Cyclic sulfone derivatives
|
|
CA2298617A1
(en)
|
1997-07-31 |
1999-02-11 |
Yetunde Olabisi Taiwo |
Acyclic metalloprotease inhibitors
|
|
DE19741235A1
(de)
*
|
1997-09-18 |
1999-03-25 |
Hoechst Marion Roussel De Gmbh |
Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
|
|
ZA988967B
(en)
*
|
1997-10-03 |
2000-04-03 |
Du Pont Pharm Co |
Lactam metalloprotease inhibitors.
|
|
US6403632B1
(en)
|
2000-03-01 |
2002-06-11 |
Bristol Myers Squibb Pharma Co |
Lactam metalloprotease inhibitors
|
|
EP1024134A4
(en)
*
|
1997-10-09 |
2003-05-14 |
Ono Pharmaceutical Co |
DERIVATIVES OF AMINOBUTANIC ACID
|
|
DK1004578T3
(da)
*
|
1998-11-05 |
2004-06-28 |
Pfizer Prod Inc |
5-oxo-pyrrolidin-2-carboxylsyrehydroxamidderivater
|
|
GB9825988D0
(en)
*
|
1998-11-27 |
1999-01-20 |
Pfizer Ltd |
Indole derivatives
|
|
US20040122011A1
(en)
*
|
1998-12-23 |
2004-06-24 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
|
|
RU2001126721A
(ru)
|
1999-03-03 |
2004-02-20 |
Дзе Проктер Энд Гэмбл Компани (US) |
Алкенил-и алкинилсодержащие ингибиторы металлопротезы
|
|
RU2001126719A
(ru)
|
1999-03-03 |
2004-02-20 |
Дзе Проктер Энд Гэмбл Компани (US) |
Дигетерозамещенные ингибиторы металлопротеазы
|
|
CA2361848A1
(en)
*
|
1999-04-02 |
2000-10-12 |
Dupont Pharmaceuticals Company |
Novel lactam inhibitors of matrix metalloproteinases, tnf-.alpha., and aggrecanase
|
|
US6797820B2
(en)
|
1999-12-17 |
2004-09-28 |
Vicuron Pharmaceuticals Inc. |
Succinate compounds, compositions and methods of use and preparation
|
|
WO2002028829A2
(en)
*
|
2000-09-25 |
2002-04-11 |
Questcor Pharmaceuticals, Inc. |
Peptide deformylase inhibitors
|
|
CA2434205A1
(en)
|
2001-01-11 |
2002-07-18 |
Dupont Pharmaceuticals Company |
1,1-disubstituted cyclic inhibitors of matrix metalloprotease and tnf-.alpha.
|
|
US6642255B2
(en)
|
2001-01-11 |
2003-11-04 |
Bristol-Myers Squibb Pharma Company |
1,2,-Disubstituted cyclic inhibitors of matrix metalloproteases and TNF-alpha
|
|
EP1363623B1
(en)
*
|
2001-03-01 |
2005-11-16 |
Smithkline Beecham Corporation |
Peptide deformylase inhibitors
|
|
AR036053A1
(es)
|
2001-06-15 |
2004-08-04 |
Versicor Inc |
Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas
|
|
EP1406893B1
(en)
*
|
2001-06-15 |
2007-04-18 |
Vicuron Pharmaceuticals, Inc. |
Pyrrolidine bicyclic compounds
|
|
PE20030701A1
(es)
|
2001-12-20 |
2003-08-21 |
Schering Corp |
Compuestos para el tratamiento de trastornos inflamatorios
|
|
TWI294778B
(en)
*
|
2002-03-13 |
2008-03-21 |
Smithkline Beecham Corp |
Peptide deformylase inhibitors
|
|
US7622117B2
(en)
*
|
2002-04-17 |
2009-11-24 |
Dynamis Therapeutics, Inc. |
3-deoxyglucosone and skin
|
|
PL374117A1
(en)
*
|
2002-05-29 |
2005-10-03 |
Merck & Co, Inc. |
Compounds useful in the treatment of anthrax and inhibiting lethal factor
|
|
US20050176686A1
(en)
*
|
2002-07-23 |
2005-08-11 |
4Sc Ag |
Novel compounds as histone deacetylase inhibitors
|
|
WO2004101523A1
(en)
*
|
2003-05-17 |
2004-11-25 |
Korea Research Institute Of Bioscience And Biotechnology |
Novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same
|
|
US7122560B2
(en)
|
2003-06-18 |
2006-10-17 |
Bristol-Myers Squibb Company |
Lactam derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme
|
|
EP1663201A4
(en)
*
|
2003-07-15 |
2009-10-28 |
Korea Res Inst Of Bioscience |
USE OF NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
|
|
RU2368390C2
(ru)
*
|
2003-07-23 |
2009-09-27 |
Новартис Аг |
Применение кальцитонина при остеоартрите
|
|
JP2007537256A
(ja)
*
|
2004-05-11 |
2007-12-20 |
メルク エンド カムパニー インコーポレーテッド |
N−スルホン化アミノ酸誘導体調製のためのプロセス
|
|
US20100003276A1
(en)
*
|
2004-12-07 |
2010-01-07 |
Hermes Jeffery D |
Methods for treating anthrax and inhibiting lethal factor
|
|
DE102004060229A1
(de)
*
|
2004-12-15 |
2006-06-29 |
Sanofi-Aventis Deutschland Gmbh |
Neue zyklische Harnstoffe als Inhibitoren von Metallproteasen
|
|
US20080287516A1
(en)
*
|
2005-01-28 |
2008-11-20 |
Irm Llc |
Phenyl-Substituted Pyrrolidones
|
|
GB0811643D0
(en)
|
2008-06-25 |
2008-07-30 |
Cancer Rec Tech Ltd |
New therapeutic agents
|
|
FR2947268B1
(fr)
*
|
2009-06-30 |
2011-08-26 |
Galderma Res & Dev |
Nouveaux composes benzene-sulfonamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique
|
|
WO2012031298A2
(en)
|
2010-09-03 |
2012-03-08 |
Duke University |
Ethynylbenzene derivatives
|
|
US20140081017A1
(en)
*
|
2012-09-14 |
2014-03-20 |
Methylgene Inc. |
Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents
|
|
US9908851B2
(en)
|
2013-08-16 |
2018-03-06 |
Duke University |
2-piperidinyl substituted N,3-dihydroxybutanamides
|
|
EP3041354A4
(en)
|
2013-08-16 |
2017-06-14 |
Duke University |
Substituted hydroxamic acid compounds
|
|
US10189786B2
(en)
|
2013-08-16 |
2019-01-29 |
Duke University |
Antibacterial compounds
|
|
GB201517216D0
(en)
|
2015-09-29 |
2015-11-11 |
Cancer Res Technology Ltd And Astex Therapeutics Ltd |
Pharmaceutical compounds
|
|
GB201517217D0
(en)
|
2015-09-29 |
2015-11-11 |
Astex Therapeutics Ltd And Cancer Res Technology Ltd |
Pharmaceutical compounds
|
|
GB201704966D0
(en)
|
2017-03-28 |
2017-05-10 |
Astex Therapeutics Ltd |
Pharmaceutical compounds
|
|
GB201704965D0
(en)
|
2017-03-28 |
2017-05-10 |
Astex Therapeutics Ltd |
Pharmaceutical compounds
|