JP2000504731A5 - - Google Patents

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Publication number
JP2000504731A5
JP2000504731A5 JP1997529647A JP52964797A JP2000504731A5 JP 2000504731 A5 JP2000504731 A5 JP 2000504731A5 JP 1997529647 A JP1997529647 A JP 1997529647A JP 52964797 A JP52964797 A JP 52964797A JP 2000504731 A5 JP2000504731 A5 JP 2000504731A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997529647A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000504731A (ja
JP4212112B2 (ja
Filing date
Publication date
Priority claimed from GBGB9605044.8A external-priority patent/GB9605044D0/en
Priority claimed from GBGB9605046.3A external-priority patent/GB9605046D0/en
Priority claimed from GBGB9605045.5A external-priority patent/GB9605045D0/en
Application filed filed Critical
Priority claimed from PCT/US1997/003039 external-priority patent/WO1997030707A1/en
Publication of JP2000504731A publication Critical patent/JP2000504731A/ja
Publication of JP2000504731A5 publication Critical patent/JP2000504731A5/ja
Application granted granted Critical
Publication of JP4212112B2 publication Critical patent/JP4212112B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP52964797A 1996-02-23 1997-02-20 非ペプチジルバソプレッシンV1aアンタゴニスト Expired - Lifetime JP4212112B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US1221596P 1996-02-23 1996-02-23
US1214996P 1996-02-23 1996-02-23
US1218896P 1996-02-23 1996-02-23
GB9605044.8 1996-03-09
GB9605045.5 1996-03-09
GB60/012,215 1996-03-09
GB9605046.3 1996-03-09
GB60/012,188 1996-03-09
GB60/012,149 1996-03-09
GBGB9605044.8A GB9605044D0 (en) 1996-03-09 1996-03-09 Method and non-peptidyl agents for modulation of the vasopressin v1a receptor
GBGB9605046.3A GB9605046D0 (en) 1996-03-09 1996-03-09 Method for antagonism of the tachykinin receptor with non-peptide agents
GBGB9605045.5A GB9605045D0 (en) 1996-03-09 1996-03-09 Method and non-peptidyl agents for modulation of the oxytocin receptor
PCT/US1997/003039 WO1997030707A1 (en) 1996-02-23 1997-02-20 NON-PEPTIDYL VASOPRESSIN V1a ANTAGONISTS

Publications (3)

Publication Number Publication Date
JP2000504731A JP2000504731A (ja) 2000-04-18
JP2000504731A5 true JP2000504731A5 (enExample) 2004-11-18
JP4212112B2 JP4212112B2 (ja) 2009-01-21

Family

ID=27547258

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52964797A Expired - Lifetime JP4212112B2 (ja) 1996-02-23 1997-02-20 非ペプチジルバソプレッシンV1aアンタゴニスト

Country Status (10)

Country Link
US (3) US6204260B1 (enExample)
EP (1) EP0939632B1 (enExample)
JP (1) JP4212112B2 (enExample)
AT (1) ATE305781T1 (enExample)
AU (1) AU1977997A (enExample)
CA (1) CA2246753C (enExample)
DE (1) DE69734321T2 (enExample)
DK (1) DK0939632T3 (enExample)
ES (1) ES2248840T3 (enExample)
WO (1) WO1997030707A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6426342B2 (en) * 1999-08-16 2002-07-30 Revaax Pharmaceuticals, Llc Use of β-lactamase inhibitors as neuroprotectants
US6489319B2 (en) * 1999-08-16 2002-12-03 Revaax Pharmaceuticals, Llc Neurotherapeutic use of carboxypeptidase inhibitors
CN1382047A (zh) * 1999-08-16 2002-11-27 雷瓦尔克斯药品有限公司 神经病治疗组合物和方法
BR0015299A (pt) 1999-11-04 2003-04-15 Johnson & Johnson Benzotiazepinas substituìdas não-peptìdicas como antagonistas de vasopressina
DK1406893T3 (da) 2001-06-15 2007-08-06 Vicuron Pharm Inc Bicykliske pyrrolidinforbindelser
AR036053A1 (es) 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas
JP4494015B2 (ja) * 2001-10-12 2010-06-30 アゼヴァン ファーマスーティカルズ,インコーポレイテッド β−ラクタミル・バソプレッシンV1a拮抗剤
WO2003051314A2 (en) * 2001-12-18 2003-06-26 Medallion Biomedical, Llc Antibiotic compounds
US20050282814A1 (en) * 2002-10-03 2005-12-22 Targegen, Inc. Vasculostatic agents and methods of use thereof
WO2004030635A2 (en) * 2002-10-03 2004-04-15 Targegen, Inc. Vasculostatic agents and methods of use thereof
TW200526651A (en) * 2003-10-03 2005-08-16 Serenix Pharmaceuticals Llc 3-substituted β-lactamyl vasopressin V1a antagonists
EP1809614B1 (en) 2004-04-08 2014-05-07 TargeGen, Inc. Benzotriazine inhibitors of kinases
PL382308A1 (pl) 2004-08-25 2007-08-20 Targegen, Inc. Związki heterocykliczne i sposoby stosowania
AU2013206201B2 (en) * 2005-03-22 2016-06-16 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
WO2006102308A2 (en) * 2005-03-22 2006-09-28 Azevan Pharmaceuticals, Inc. Beta-lactamyl vasopressin v1b antagonists
US20060292203A1 (en) * 2005-06-08 2006-12-28 Targegen, Inc. Methods and compositions for the treatment of ocular disorders
JP5328349B2 (ja) * 2005-07-19 2013-10-30 アゼヴァン ファーマスーティカルズ,インコーポレイテッド ベータ−ラクタミルフェニルアラニン、システイン、およびセリン・バソプレッシン拮抗剤
US8604042B2 (en) * 2005-11-01 2013-12-10 Targegen, Inc. Bi-aryl meta-pyrimidine inhibitors of kinases
MX391408B (es) * 2005-11-01 2025-03-21 Impact Biomedicines Inc Inhibidores de biaril meta-pirimidina de cinasas.
US8133900B2 (en) * 2005-11-01 2012-03-13 Targegen, Inc. Use of bi-aryl meta-pyrimidine inhibitors of kinases
WO2007127366A2 (en) * 2006-04-25 2007-11-08 Targegen, Inc. Kinase inhibitors and methods of use thereof
US20100016274A1 (en) * 2006-09-14 2010-01-21 Koppel Gary A Beta-lactam cannabinoid receptor modulators
CN102413814A (zh) * 2009-04-29 2012-04-11 瑞恩药品公司 用于神经保护和治疗神经变性病症的克拉维酸类物质制剂
JP2013535425A (ja) 2010-07-01 2013-09-12 アゼヴァン ファーマシューティカルズ,インコーポレイテッド 心的外傷後ストレス障害を治療する方法
CA2816957A1 (en) 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
JP7255967B2 (ja) 2014-03-28 2023-04-11 アゼヴァン ファーマスーティカルズ,インコーポレイテッド 神経変性疾患を治療するための組成物および方法
CN111295373B (zh) * 2017-09-15 2024-12-10 阿泽凡药物公司 用于治疗脑损伤的组合物和方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751299A (en) 1983-11-18 1988-06-14 Takeda Chemical Industries, Ltd. Optically active β-lactams and method of their production
US4665171A (en) 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics
US4673737A (en) 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof
EP0215435B1 (en) 1985-09-09 1993-03-03 Otsuka Pharmaceutical Co., Ltd. 2-oxa-isocephem compounds, compositions containing same and processes for preparing same
US4734498A (en) 1986-07-10 1988-03-29 Eli Lilly And Company 3β-succinimidoazetidinones as chiral intermediates
US4772694A (en) * 1986-07-24 1988-09-20 Eli Lilly And Company Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates
DK123488A (da) 1987-03-09 1988-09-10 Otsuka Pharma Co Ltd 2-oxa-isocephemforbindelser, praeparater indeholdende dem, og fremgangsmaader til fremstilling af dem
US5373089A (en) 1988-09-02 1994-12-13 Northwestern University Oxytocin antagonist
US5068232A (en) 1990-04-10 1991-11-26 American Cyanamid Company Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them
US5521307A (en) * 1992-02-18 1996-05-28 Eli Lilly And Company Methods and compounds for the preparation of carbacephems
CA2147129A1 (en) * 1992-10-27 1994-05-11 James B. Doherty New substituted azetidinones as anti-inflammatory and antidegenerative agents
US5631365A (en) * 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
WO1996016333A1 (en) * 1994-11-23 1996-05-30 Affymax Technologies, N.V. METHODS FOR SYNTHESIZING DIVERSE COLLECTIONS OF β-LACTAM COMPOUNDS
JPH11503728A (ja) * 1995-03-31 1999-03-30 シンファー ラボラトリーズ,インコーポレーティッド システイン・プロテイナーゼ阻害剤として有用な新規な4−置換−3−ペプチジル−アゼチジン−2−オン誘導体
AU5487496A (en) * 1995-05-03 1996-11-21 Eli Lilly And Company Combinatorial process for synthesizing azetidinone analogs

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