JP2000504731A5 - - Google Patents

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Publication number
JP2000504731A5
JP2000504731A5 JP1997529647A JP52964797A JP2000504731A5 JP 2000504731 A5 JP2000504731 A5 JP 2000504731A5 JP 1997529647 A JP1997529647 A JP 1997529647A JP 52964797 A JP52964797 A JP 52964797A JP 2000504731 A5 JP2000504731 A5 JP 2000504731A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997529647A
Other languages
English (en)
Japanese (ja)
Other versions
JP4212112B2 (ja
JP2000504731A (ja
Filing date
Publication date
Priority claimed from GBGB9605046.3A external-priority patent/GB9605046D0/en
Priority claimed from GBGB9605044.8A external-priority patent/GB9605044D0/en
Priority claimed from GBGB9605045.5A external-priority patent/GB9605045D0/en
Application filed filed Critical
Priority claimed from PCT/US1997/003039 external-priority patent/WO1997030707A1/en
Publication of JP2000504731A publication Critical patent/JP2000504731A/ja
Publication of JP2000504731A5 publication Critical patent/JP2000504731A5/ja
Application granted granted Critical
Publication of JP4212112B2 publication Critical patent/JP4212112B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP52964797A 1996-02-23 1997-02-20 非ペプチジルバソプレッシンV1aアンタゴニスト Expired - Lifetime JP4212112B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US1218896P 1996-02-23 1996-02-23
US1221596P 1996-02-23 1996-02-23
US1214996P 1996-02-23 1996-02-23
GB9605044.8 1996-03-09
GB9605045.5 1996-03-09
GBGB9605046.3A GB9605046D0 (en) 1996-03-09 1996-03-09 Method for antagonism of the tachykinin receptor with non-peptide agents
GB9605046.3 1996-03-09
GB60/012,215 1996-03-09
GBGB9605044.8A GB9605044D0 (en) 1996-03-09 1996-03-09 Method and non-peptidyl agents for modulation of the vasopressin v1a receptor
GB60/012,188 1996-03-09
GBGB9605045.5A GB9605045D0 (en) 1996-03-09 1996-03-09 Method and non-peptidyl agents for modulation of the oxytocin receptor
GB60/012,149 1996-03-09
PCT/US1997/003039 WO1997030707A1 (en) 1996-02-23 1997-02-20 NON-PEPTIDYL VASOPRESSIN V1a ANTAGONISTS

Publications (3)

Publication Number Publication Date
JP2000504731A JP2000504731A (ja) 2000-04-18
JP2000504731A5 true JP2000504731A5 (Direct) 2004-11-18
JP4212112B2 JP4212112B2 (ja) 2009-01-21

Family

ID=27547258

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52964797A Expired - Lifetime JP4212112B2 (ja) 1996-02-23 1997-02-20 非ペプチジルバソプレッシンV1aアンタゴニスト

Country Status (10)

Country Link
US (3) US6204260B1 (Direct)
EP (1) EP0939632B1 (Direct)
JP (1) JP4212112B2 (Direct)
AT (1) ATE305781T1 (Direct)
AU (1) AU1977997A (Direct)
CA (1) CA2246753C (Direct)
DE (1) DE69734321T2 (Direct)
DK (1) DK0939632T3 (Direct)
ES (1) ES2248840T3 (Direct)
WO (1) WO1997030707A1 (Direct)

Families Citing this family (27)

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US6489319B2 (en) * 1999-08-16 2002-12-03 Revaax Pharmaceuticals, Llc Neurotherapeutic use of carboxypeptidase inhibitors
US6426342B2 (en) * 1999-08-16 2002-07-30 Revaax Pharmaceuticals, Llc Use of β-lactamase inhibitors as neuroprotectants
NZ517663A (en) * 1999-08-16 2006-02-24 Revaax Pharmaceuticals Llc Neurotherapeutic clavulanate composition and method
BR0015299A (pt) 1999-11-04 2003-04-15 Johnson & Johnson Benzotiazepinas substituìdas não-peptìdicas como antagonistas de vasopressina
ATE360014T1 (de) 2001-06-15 2007-05-15 Vicuron Pharm Inc Bicyclische pyrrolidinverbindungen
AR036053A1 (es) 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas
CN101921267A (zh) * 2001-10-12 2010-12-22 阿泽范药品公司 β-内酰胺后叶加压素V1a拮抗剂
WO2003051314A2 (en) * 2001-12-18 2003-06-26 Medallion Biomedical, Llc Antibiotic compounds
US20050282814A1 (en) * 2002-10-03 2005-12-22 Targegen, Inc. Vasculostatic agents and methods of use thereof
BR0315053A (pt) * 2002-10-03 2005-08-09 Targegen Inc Agentes vasculostáticos , composição, artigo e processo de preparação dos mesmos
WO2005035492A1 (en) * 2003-10-03 2005-04-21 Serenix Pharmaceuticals, Llc. 3-SUBSTITUTED β-LACTAMYL VASOPRESSIN V1A ANTAGONISTS
AU2005231507B2 (en) 2004-04-08 2012-03-01 Targegen, Inc. Benzotriazine inhibitors of kinases
EP1799656A4 (en) 2004-08-25 2009-09-02 Targegen Inc HETEROCYCLIC COMPOUNDS AND METHODS OF USE
AU2013206201B2 (en) * 2005-03-22 2016-06-16 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
US9597314B2 (en) * 2005-03-22 2017-03-21 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
CA2611720A1 (en) * 2005-06-08 2006-12-14 Targegen, Inc. Methods and compositions for the treatment of ocular disorders
US8048874B2 (en) * 2005-07-19 2011-11-01 Azevan Pharmaceuticals, Inc. Beta-lactamyl phenylalanine, cysteine, and serine vasopressin antagonists
HUE028987T2 (en) * 2005-11-01 2017-01-30 Targegen Inc Bi-aryl meta-pyrimidine inhibitors of kinases
US8604042B2 (en) * 2005-11-01 2013-12-10 Targegen, Inc. Bi-aryl meta-pyrimidine inhibitors of kinases
US8133900B2 (en) * 2005-11-01 2012-03-13 Targegen, Inc. Use of bi-aryl meta-pyrimidine inhibitors of kinases
US7691858B2 (en) * 2006-04-25 2010-04-06 Targegen, Inc. Kinase inhibitors and methods of use thereof
US20100016274A1 (en) * 2006-09-14 2010-01-21 Koppel Gary A Beta-lactam cannabinoid receptor modulators
CN102413814A (zh) * 2009-04-29 2012-04-11 瑞恩药品公司 用于神经保护和治疗神经变性病症的克拉维酸类物质制剂
ES2662350T3 (es) * 2010-07-01 2018-04-06 Azevan Pharmaceuticals, Inc. Procedimientos para el tratamiento del trastorno por estrés postraumático
WO2012060847A1 (en) 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
MX382453B (es) 2014-03-28 2025-03-13 Azevan Pharmaceuticals Inc Composiciones y metodos para tratar enfermedades neurodegenerativas
CN111295373B (zh) 2017-09-15 2024-12-10 阿泽凡药物公司 用于治疗脑损伤的组合物和方法

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
US4751299A (en) 1983-11-18 1988-06-14 Takeda Chemical Industries, Ltd. Optically active β-lactams and method of their production
US4665171A (en) 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics
US4673737A (en) 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof
DE3687870T2 (de) 1985-09-09 1993-08-19 Otsuka Pharma Co Ltd 2-oxa-isocephemverbindungen, sie enthaltende zusammensetzungen und verfahren zu deren herstellung.
US4734498A (en) 1986-07-10 1988-03-29 Eli Lilly And Company 3β-succinimidoazetidinones as chiral intermediates
US4772694A (en) * 1986-07-24 1988-09-20 Eli Lilly And Company Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates
DK123488A (da) 1987-03-09 1988-09-10 Otsuka Pharma Co Ltd 2-oxa-isocephemforbindelser, praeparater indeholdende dem, og fremgangsmaader til fremstilling af dem
US5373089A (en) 1988-09-02 1994-12-13 Northwestern University Oxytocin antagonist
US5068232A (en) 1990-04-10 1991-11-26 American Cyanamid Company Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them
US5521307A (en) 1992-02-18 1996-05-28 Eli Lilly And Company Methods and compounds for the preparation of carbacephems
JPH08502752A (ja) * 1992-10-27 1996-03-26 メルク エンド カンパニー インコーポレーテッド 抗炎症剤及び抗変性剤としての新規の置換アゼチジノン
US5631365A (en) * 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
WO1996016333A1 (en) * 1994-11-23 1996-05-30 Affymax Technologies, N.V. METHODS FOR SYNTHESIZING DIVERSE COLLECTIONS OF β-LACTAM COMPOUNDS
DE69610978D1 (de) * 1995-03-31 2000-12-21 Naeja Pharmaceutical Inc 4-substituierte-3-peptidyl-azetidin-2-on-derivate als cystein-proteinase inhibitoren
WO1996035122A1 (en) * 1995-05-03 1996-11-07 Eli Lilly And Company Combinatorial process for synthesizing azetidinone analogs

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