JP2000355516A - New composition for cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a composition for cosmetic imparting moisture to skin, having excellent moisture permeability, free from imparting feeling of blockage, excellent in senses such as moisture, etc., in dry state when used to hair, useful for facial cleansing agent, etc., by combinedly using humectants and oily materials. SOLUTION: This composition for cosmetic includes an ester of an N-long chain acyl neutral amino acid of the formula (R1 is a 5-21C alkyl, etc., R2 is H, etc., R3 is H, etc., R4 is a 1-10C alkyl, etc., m is 0-2) having a 6-22C acryl group and an alcoholic part comprising a 1-10C hydrocarbon or/and a diester of an N-long chain acyl neutral amino acid having a 6-22C acyl group and an alcoholic part comprising a 1-10C hydrocarbon and hymectants (e.g. glycerin) as active ingredients.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a novel cosmetic composition, and more particularly, to a composition containing an N-long-chain acyl neutral amino acid ester and / or an N-long-chain acyl acidic amino acid diester and a wetting agent as active ingredients. And a cosmetic composition characterized by the following.

[0002]

2. Description of the Related Art In cosmetics, humectants are used for the purpose of absorbing moisture, imparting moisture and softness and smoothness to skin and hair, and preventing drying of products (cosmetics).

[0003] Cosmetic products are usually blended with oily raw materials for the purpose of improving the feel, binding components, emollients, and maintaining the dosage form. Conventionally used oily raw materials include fatty acid esters such as liquid paraffin, isopropyl myristate (IPM), and isopropyl palmitate (IPP). Conventional oily raw materials provide moisture to the skin when used in combination with a wetting agent. However, water permeation (moisture permeability) was hindered, giving a feeling of clogging, and was not satisfactory in terms of sensuality. In addition, when used for hair, it was satisfactory in moisture during drying, but was not sufficiently satisfactory in imparting smoothness during rinsing.

[0004]

SUMMARY OF THE INVENTION Under the background of the prior art described in the preceding paragraph, an object of the present invention is to provide moisture to the skin by using a humectant and an oily material in combination, to have excellent moisture permeability, An object of the present invention is to provide a cosmetic composition which does not give a feeling and which is excellent in sensuality such as imparting not only moisture when dried but also smoothness when washed away when used on hair.

[0005]

Means for Solving the Problems The present inventor has conducted intensive studies in order to achieve the above-mentioned object, and as a result, has found that a wetting agent and a specific N-
It has been found that the above problems can be solved by using a long-chain acyl neutral amino acid ester and / or an N-long-chain acyl acidic amino acid diester in combination, and the present invention has been completed based on such findings. Was.

[0006] That is, the present invention provides a method for preparing a compound having 6 to 22 carbon atoms.
An ester of an N-long-chain acyl-neutral amino acid having a linear or branched saturated or unsaturated acyl group, wherein the hydrocarbon group constituting the alcohol moiety has 1 to 1 carbon atoms.
N-long-chain acyl-neutral amino acid ester which is 10 straight-chain or branched-chain saturated or unsaturated hydrocarbon groups (component A)
And / or a N-long chain acyl acidic amino acid having a linear or branched saturated or unsaturated acyl group having 6 to 22 carbon atoms, wherein the hydrocarbon group constituting the alcohol site is a carbon atom. It contains an N-long-chain acyl acidic amino acid diester (Component B) and a wetting agent (Component C), which are linear or branched saturated or branched hydrocarbon groups of Formulas 1 to 10, as active ingredients. And a cosmetic composition.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the present invention will be described in detail.

First, the N-long-chain acyl neutral amino acid ester (component A) according to the present invention will be described in detail.

In the present invention, the long-chain acyl group of the N-long-chain acyl neutral amino acid ester has 6 to 2 carbon atoms.
2, straight or branched saturated or unsaturated, for example, capric acid, lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, linoleic acid, linoleic acid, oleic acid, isostearic acid, -An acyl group which can be derived from ethylhexanoic acid, coconut oil fatty acid, tallow oil fatty acid, hardened tallow oil fatty acid and the like. Preferred acyl groups include caproyl acid, lauroyl group, myristyl group, palmitoyl group,
Examples include a stearoyl group, a behenoyl group, a cocoyl group, a hydrogenated tallow oil fatty acid acyl group, and the like.

The neutral amino acids constituting the neutral amino acid site include glycine, alanine, valine, leucine, isoleucine, serine, threonine, proline, β-alanine, aminobutyric acid, sarcosine, N-methyl-β-alanine and the like. Neutral amino acids. Preferably, glycine, alanine, β-alanine, α-aminobutyric acid, γ-
Aminobutyric acid, sarcosine and N-methyl-β-alanine, particularly preferred are sarcosine, alanine, glycine and N-methyl-β-alanine. These amino acids may be optically active or racemic.

The hydrocarbon group constituting the alcohol moiety is a branched or straight-chain alkyl or alkenyl group having 1 to 10 carbon atoms, preferably an alkyl group such as methanol, ethanol, Propanol, isopropanol, butanol, t-butanol,
Isobutanol, hexanol, cyclohexanol,
Examples include hydrocarbon groups that can be derived from octanol, 2-ethylhexanol, decanol, and the like. Further, a branched or straight-chain alkyl group having 1 to 4 carbon atoms is more preferable from the viewpoint of usability, and among them, a branched or straight-chain alkyl group having 2 to 4 carbon atoms is more preferable. Is mentioned. In addition to the feeling of use and the stability of hydrolysis, a branched alkyl group having 3 to 4 carbon atoms is particularly preferable, and examples thereof include an isopropyl group, a t-butyl group, and an isobutyl group. Among them, the most preferred is an isopropyl group.

A preferred example of the N-long-chain acyl-neutral amino acid ester in the present invention is represented by the following general formula and includes those represented by the following general formula (1).

[0013]

Embedded image

(Wherein R¹Is a straight chain having 5 to 21 carbon atoms
Or a branched alkyl or alkenyl group represented by R²Is water
A linear or branched alkyl having 1 to 3 carbon atoms
A group represented by R³Is a hydrogen atom or a straight-chain or
Represents a branched alkyl group, R ⁴Represents 1 to 10 carbon atoms
A branched or straight-chain alkyl or alkenyl group
And m represents an integer of 0 to 2. )

In the general formula (1), an acyl group (R ¹ -CO
-) and Preferred as R ⁴ hydrocarbon groups constituting the alcohol moiety is as described above. Preferred amino acid sites are also as described above.

The N-long-chain acyl-neutral amino acid ester in the present invention can be obtained, for example, by subjecting an N-long-chain acyl-neutral amino acid and an alcohol to thermal dehydration condensation esterification under normal pressure or reduced pressure. Further, an azeotropic dehydration-condensation reaction or a transesterification reaction using a solvent such as toluene can also be used. The N-long-chain acyl-neutral amino acid and the alcohol used for the synthesis of such N-long-chain acyl-neutral amino acid ester do not necessarily need to be a single compound. -It may be a mixture of long-chain acyl neutral amino acids or a mixture of alcohols having different chain lengths.

By the way, N-long-chain acyl neutral amino acids are
For example, it can be produced by a known method such as a so-called Schotten-Baumann reaction in which a long-chain fatty acid halide is reacted with an amino acid in the presence of a basic catalyst (see Japanese Patent Publication No. 51-38681).

Next, the N-long-chain acyl acidic amino acid diester (component B) will be described in detail.

The long-chain acyl group of the N-long-chain acyl acidic amino acid diester in the present invention is the same as the long-chain acyl group of the N-long-chain acyl neutral amino acid ester described above, and the preferred acyl group is also the same. is there.

The acidic amino acids constituting the acidic amino acid site include glutamic acid and aspartic acid. Particularly preferred is glutamic acid. These amino acids may be optically active or racemic.

The alcohol moiety is the same as the long-chain acyl group of the N-long-chain acyl neutral amino acid ester described above, and the preferred one is also the same.

Preferred examples of the N-long-chain acyl acidic amino acid diester in the present invention are represented by the following general formula, and include those represented by the following general formula (2).

[0023]

Embedded image

[0024] (wherein, ^{R 5} represents a branched or straight chain alkyl group or alkenyl group of 5 to 21 carbon atoms, ^{R 6}
And R ⁷ each independently represent a linear or branched alkyl or alkenyl group having 1 to 10 carbon atoms, and n represents an integer of 0 or 1. )

The N-long-chain acyl acidic amino acid diester in the present invention can be obtained, for example, by subjecting an N-long-chain acyl acidic amino acid and an alcohol to heat dehydration condensation esterification under normal pressure or reduced pressure. In addition, an azeotropic dehydration condensation reaction or a transesterification reaction using toluene or the like as a solvent can also be used. The N-long chain acyl acidic amino acid diester used in the synthesis of such N-long chain acyl acidic amino acid diester does not necessarily need to be a single compound, and N-long chains having different types of acyl groups and acidic amino acids are not necessarily required. It may be a mixture of acyl acidic amino acids or a mixture of alcohols having different chain lengths.

Incidentally, N-long-chain acyl acidic amino acids are
For example, the so-called Schotten-Baumann reaction in which a long-chain fatty acid halide is reacted with an amino acid in the presence of a basic catalyst (JP-B-46-8865, JP-B-48-35058, JP-B-51)
For example, see Japanese Patent No. 38681).

These N-long-chain acyl neutral amino acid esters (component A) and N-long-chain acyl acidic amino acid diesters (component B) have low irritation to the skin and mucous membranes. Has high moisture permeability and does not give a feeling of blockage. In addition, oily raw materials for cosmetics, especially because it has excellent organoleptic properties such as good spreadability to the skin, good familiarity, and smoothness, and moisture when used on hair, as well as moisture when dried and smoothness when washed off. It is excellent to use as. In particular, N-long-chain acyl neutral amino acid esters are free from the unpleasant oily feeling and sticky feeling peculiar to oily raw materials, are excellent in refreshing or light feeling, and are suitable for use in cosmetics. Preferred over acidic amino acid diesters.

Next, the wetting agent (component C) will be described.

The humectant is used for the purpose of absorbing moisture from the air, giving moisture and softness and smoothness to the skin, and for preventing the product from drying out. Examples thereof include polyhydric alcohol and keratin. NMF (Natural M
a hydrophilic substance, a saccharide, a polysaccharide or a polysaccharide derivative, called an oisturing factor (natural moisturizing factor);
Polyamino acids and derivatives thereof, amino acid derivatives such as betaine and the like can be mentioned. The humectant performs the above-mentioned important function in the cosmetic ingredient, but may be used as a bacteriostatic action or a flavor retention agent.

Specific examples of the aforementioned wetting agent (component C) are described below.

Examples of polyhydric alcohols include glycerin, propylene glycol, 1,3-butylene glycol, isoprene glycol, polyethylene glycol,
Diglycerin, triglycerin, tetraglycerin, pentaglycerin, hexaglycerin, decaglycerin,
Sorbitol, ethylene glycol, erythritol and the like.

Examples of NMF include amino acids such as proline, glycine, alanine, serine, threonine, arginine, glutamic acid, aspartic acid, leucine, isoleucine, valine, pyrrolidone carboxylic acid, pyrrolidone carboxylate, lactic acid, lactate, urea, Glucosamine, creatine, citrate and the like can be mentioned.

As the saccharide, polysaccharide and polysaccharide derivative,
Sucrose, lactose, trehalose, natural oligosaccharides, hyaluronic acid, its sodium salt, chondroitin sulfate and the like.

Polyamino acids, derivatives thereof, and other amino acid derivatives include polyglutamic acid and polyamino acid containing polyaspartic acid and salts thereof, soybean protein decomposed products,
Deoxyribonucleic acid, glycine betaine, chitin, chitosan, deacetylated chitin and the like can be mentioned.

The novel cosmetic composition of the present invention contains, in addition to the components A and / or B and C described above, various commonly used additives within a range not to impair the effects of the present invention. It can be added as an optional component. Examples include surfactants, silicone compounds, polymeric substances (polymeric compounds), alcohols, UV absorbers, dyes, pigments, vitamins, antioxidants, sequestering agents, preservatives, bactericides, anti-inflammatory Ingredients, pH adjusters, pearling agents, nucleic acids, enzymes, natural extracts, etc., cosmetic ingredients standards, compounding varieties for cosmetic varieties, raw materials standards of the Japanese Pharmacopoeia, Japanese Pharmacopoeia, official ingredients of food additives, etc. .

Examples of the surfactant include an alkyl sulfate, an alkyl phosphate, a polyoxyethylene alkyl ether sulfate, a polyoxyethylene alkyl phenyl ether sulfate, a polyoxyethylene alkyl carboxylate, and an alkyl phenyl ether sulfonic acid. Salts, salts of alkylsulfosuccinic acid and its derivatives, salts of N-acylsarcosine and its derivatives, N-acyl-N-methyl-β
-Anionic surfactants such as alanine salts, polyoxyethylene coconut oil fatty acid monoethanolamide sulfate, polyoxyethylene alkyl ether phosphate, higher fatty acid salts, N-acylglycine salts, N-acylalanine salts; carbobetaine type Amphoteric surfactants, sulfobetaine-type amphoteric surfactants, hydroxysulfobetaine-type amphoteric surfactants, amidosulfobetaine-type amphoteric surfactants, phosphobetaine-type amphoteric surfactants, imidazoline-type amphoteric surfactants, lecithin derivatives and the like Amphoteric surfactants: propylene glycol fatty acid ester, glycerin fatty acid ester,
Polyoxyethylene glycerin fatty acid ester, polyglycerin fatty acid ester, sorbitan fatty acid ester,
Polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbite fatty acid ester, polyoxyethylene alkylphenyl formaldehyde condensate, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyethylene sterol and derivatives thereof,
Polyethylene glycol fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene polyoxypropylene alkyl ether, polyoxyethylene alkyl phenyl ether, polyoxyethylene lanolin and derivatives thereof, polyoxyethylene beeswax derivative,
Nonionic surfactants such as polyoxyethylene alkylamine, polyoxyethylene fatty acid amide, alkanolamide, sugar esters, polyoxyethylene hydrogenated castor oil pyroglutamate, polyoxyethylene glyceryl pyroglutamate, and the like; quaternary ammonium salts, amidoamines And N-acyl arginine ester salts and N- [3-alkyloxy-2-hydroxypropyl] -L-arginine salts. In addition, as a salt of an anionic surfactant, sodium, magnesium, potassium, ammonium, diethanolamine, triethanolamine, arginine,
Lysine salts and the like can be mentioned, and these various surfactants can be added.

Examples of the silicone compound include methylpolysiloxane, highly polymerized methylpolysiloxane, polyoxyethylene / methylpolysiloxane copolymer, polyoxypropylene / methylpolysiloxane copolymer and poly (oxyethylene, oxypropylene). Ether modified silicone such as methylpolysiloxane copolymer, stearoxymethylpolysiloxane, stearoxytrimethylsilane, methylhydrogenpolysiloxane, octamethylpolysiloxane, decamethylpolysiloxane, decamethylcyclopentasiloxane, octamethylcyclotetra Cyclic silicones such as siloxane, tetrahydrotetramethylcyclotetrasiloxane, methylcyclopolysiloxane and dodecamethylcyclohexasiloxane;
Amino-modified silicone such as methylphenylpolysiloxane, trimethylsiloxysilicic acid, aminoethylaminopropylsiloxane / dimethylsiloxane copolymer, silanol-modified polysiloxane, alkoxy-modified polysiloxane, fatty acid-modified polysiloxane, fluorine-modified polysiloxane, epoxy-modified poly Siloxane, alkoxy-modified polysiloxane perfluoropolyether, polyvinyl acetate dimethylpolysiloxane, and one or two of these
Silicone emulsions in which seeds or more are emulsified are exemplified.

Examples of high molecular substances (high molecular compounds) include plant polysaccharide polymers such as guar gum, locust bingham, quince seed, carrageenan, galactan, arabic gum, tragacanth gum, pectin, mannan, starch, pullulan, and xanthan gum. , Dextran, succinoglucan, curdlan, animal-based protein systems such as gelatin, casein, albumin, collagen and the like derived from microorganisms such as hyaluronic acid, methylcellulose, ethylcellulose, hydroxyethylcellulose,
Hydroxypropyl cellulose, carboxymethyl cellulose and its salts, cellulose derivatives such as methylhydroxypropyl cellulose, soluble starch, carboxyl starch, starch derivatives such as methyl starch, alginic acid propylene glycol ester, alginic acid derivatives such as alginates, polyvinyl alcohol, polyvinyl butyral, Vinyl acetate / vinyl pyrrolidone copolymer, vinyl acetate / crotonic acid copolymer, vinyl methyl ether / ethyl maleate copolymer, vinyl methyl ether / butyl maleate copolymer, crotonic acid / vinyl acetate / vinyl neodecanoate Polymer, methoxyethylene maleic anhydride copolymer, isobutylene / sodium maleate copolymer, N-methylpyrrolidone, vinylpyrrolidone / N, N- Methylaminoethyl methacrylic acid copolymer Diethyl sulfate, vinyl imidazolium metochloride / vinyl pyrrolidone copolymer, polyvinyl pyrrolidone, vinyl pyrrolidone / styrene copolymer, vinyl pyrrolidone / hexadecene copolymer, styrene / vinyl pyrrolidone copolymer , Eicosene-vinylpyrrolidone copolymer, vinyl derivatives such as carboxyvinyl polymer, alkyl acrylate copolymer, polyacrylic acid and its salts (sodium, potassium, ammonium, triethanolamine, arginine, lysine, etc.), poly Alkyl acrylate, alkyl acrylate copolymer, acrylamide / styrene copolymer, alkyl acrylate / styrene copolymer, octylamide acrylate / acrylate copolymer and salts thereof, Octylamide acrylate / hydroxypropyl acrylate / butylaminoethyl methacrylate copolymer, acrylic resin alkanolamine, hydroxyethyl acrylate / methoxyethyl acrylate copolymer, alkyl acrylate / alkyl methacrylate / diacetone / acetone Acrylic acid derivatives such as acrylamide / methacrylic acid copolymer, dimethyldiallylammonium chloride / acrylamide copolymer, methacryloylethyldimethylbetaine / methacryloylethyltrimethylammonium chloride / methoxypolyethylene glycol methacrylate copolymer, methacryloylethyldimethylbetaine / chloride Methacryloylethyltrimethylammonium / 2-hydroxyethyl methacrylate copolymer, carboxymethyldex Strand and its salt; O- [2-hydroxy-3 chloride
Cationized cellulose such as-(trimethylammonio) propyl] hydroxyethylcellulose, O- [2-hydroxy-3- (lauryldimethylammonio) propyl] hydroxyethylcellulose; O- [2-
Hydroxy-3- (trimethylammonio) propyl]
Cationized guar gum such as guar gum, epoxy resin isostearate, polyamide epichlorohydrin resin, bisphenol epoxy resin fatty acid ester,
Polyethylene glycol / epichlorohydron / coconut oil alkylamine / dipropylenetriamine condensate; perfluoropolyether;

Examples of the alcohol include higher alcohols such as cetyl alcohol, stearyl alcohol, behenyl alcohol, isostearyl alcohol, octyl dodecanol, oleyl alcohol and myristyl alcohol, and lower alcohols such as ethanol and isopropyl alcohol.

Examples of ultraviolet absorbers include benzophenone phenone derivatives, paraaminobenzoic acid derivatives, methoxycinnamic acid derivatives, salicylic acid derivatives, urocanic acid and its derivatives, 4-tert-butyl-4'-methoxydibenzoylmethane, -(2'-hydroxy-5'-methylphenyl) benzotriazole, methyl anthranilate and the like.

Examples of dyes include Red 201 and Red 2
02, Red 204, Red 205, Red 220,
Red 226, Red 228, Red 405, Orange 20
No. 3, orange No. 204, yellow No. 205, yellow No. 401, blue No. 404, red No. 3, red No. 104, red No. 106,
Red 227, Red 230, Red 401, Red 50
No. 5, orange 205, yellow 4, yellow 5, yellow 202
No. 3, yellow No. 203, green No. 3, blue No. 1 and the like.

Examples of pigments include natural pigments such as β-carotene, calsamine and cochineal, mica, talc, kaolin, calcium carbonate, magnesium carbonate, silicic anhydride, aluminum oxide, barium sulfate, red iron oxide, black iron oxide Iron oxide, chromium oxide, ultramarine, navy blue, carbon black, titanium oxide, zinc oxide, titanium mica, fish scale foil,
Inorganic pigments such as bismuth oxychloride, boron nitride, photochromic pigment, synthetic, fluorophlogopite, iron-containing synthetic fluorophlogopite, and fine particle composite powder.

Examples of vitamins include vitamins A, B1, B2, B6 and their derivatives used as nutrients, vitamin C and its derivatives also used as whitening agents, vitamin E and its derivatives used as vasodilators Derivatives and the like.

Examples of the antioxidant include tocophenols, dibutylhydroxytoluene (BHT), butylhydroxyanisole (BHA) and the like.

Examples of sequestering agents include ethylenediaminetetraacetic acid (EDTA) sodium salt, phosphoric acid, citric acid, succinic acid, gluconic acid, polyphosphoric acid, sodium metaphosphate and the like.

Examples of preservatives include paraben derivatives, benzoic acid derivatives, salicylic acid derivatives and the like.

Examples of fungicides include benzalkonium chloride, benzethonium chloride, halocarban, 2,4,4-
Trichloro-2-hydroxyphenol, triclosan and the like.

Examples of anti-inflammatory agents include β-glycyrrhetinic acid, glycyrrhizic acid derivatives, allantoin, azulene, ε-aminocaproic acid, hydrocortisone, hinokitiol and the like.

In addition, arbutin and kojic acid as whitening agents, assemblage extract, cepharanthin, γ-oryzanol, capsicum tincture, ginger tincture, nicotinic acid benzyl ester as hair growth agents, estradiol, ethinyl estradiol, and hair root as female hormone agents Pantothenic acid and its derivatives as activators,
Placenta extract, allantoin, photosensitive element 301 and the like.

As agents for preventing rough skin, zinc oxide, zinc sulfate, allantoin hydroxyaluminum,
Aluminum chloride, aluminum sulfate, zinc sulfocarbonate, tannic acid, and menthol, camphor and the like as a cooling agent.

Further, as antihistamines, diphenhydramine hydrochloride, chlorferamine maleate, exfoliation
Solubilizing agents include sulfur, salicylic acid, resorcinol and the like.

Examples of natural product-derived drugs include refined oils such as hamamelis, odrico grass, birch, rhubarb, licorice, orchid, sicon, western sawtooth grass, aloe, chamomile, eucalyptus oil, carrot extract, aloe, sicon, lily, loofah , Marronnier, psyllium, Benihana and the like.

In addition, hydrolyzed proteins such as hydrolyzed protein collagen and hydrolyzed silk, blood-sucking insects (mosquitoes, lice,
Dimethyl phthalate, 2-ethyl-1,3-hexanediol, bisbutylenetetrahydrofurfural, N, N-diethyl-m
-Toluamide and the like.

In order to prepare the cosmetic of the present invention by blending the various components described above, there are no particular restrictions except that component A and / or component B and component C are used as essential components. Instead, it can be based on a conventionally known ordinary method.

The amount of component A and / or component B in the present invention is appropriately determined depending on the intended product and is not particularly limited, but is preferably 0.01 to 50% by weight, and more preferably 0.1 to 50% by weight. -20% by weight. 0.
If the amount is less than 01% by weight, the effects of the present invention may not be sufficiently exhibited.

The amount of component C of the present invention is appropriately determined depending on the intended product and is not particularly limited, but is preferably 0.01 to 50% by weight, more preferably 0.1 to 20% by weight. is there. If it is less than 0.01% by weight,
Moisture is not sufficiently imparted to the skin, and a feeling of obstruction is imparted. Even when used for hair, sufficient performance may not be exerted in imparting moisture when dry and smoothness when washing away.

The formulation of the cosmetic composition of the present invention is not particularly limited in the form of an emulsion, a solution, a solubilizing system, a powder dispersion, a two-layer water-oil system, a three-layer water-oil-powder system. Any dosage form, such as a layer system, may be used.

The cosmetic composition of the present invention is not particularly limited in its use, and may be used as a face wash, makeup remover, cleansing foam, cleansing cream, lotion, milky lotion, massage cream, cold cream, moisture cream, moisture cream. Gel, emollient lotion, serum, pack, after shaving lotion, white powder, foundation, lipstick, blush, eyebrow ink, mascara, shampoo, rinse, hair restorer, treatment, hair conditioner, tics, hair liquid, set lotion, permanent wave liquid , Hair cream, hair lotion, hair mousse, perm solution, hair dye,
It can be used for various cosmetics and skin external preparations such as hair color, hair manicure, soap, body shampoo, sunscreen cream, sunscreen oil, hand soap, deodorant spray, bath oil, antiperspirant, topical pharmaceutical composition, etc. .

[0059]

The present invention will be further described below with reference to comparative examples and examples.

Comparative Examples 1 to 3 and Examples 1 to 4 (skin creams): Skin creams having the compositions shown in Table 1 below (indicated by component weight%, total amount 100%) were prepared by a conventional method, and 10 specialized panelists To use these skin creams,
Sensory evaluation was performed on (a) moisture on the skin and (b) feeling of obstruction to the skin. The results are also shown in the table.

In the sensory evaluation, an average value was calculated based on the following criteria using Comparative Example 1 as a standard product. Average value is 5.0-
The case of 3.5 was judged as very good (◎), the case of 3.5 to 2.5 was judged as normal (○), and the case of 2.5 to 1.0 was judged as bad (△).

<Evaluation Criteria> (a) Moisture on the skin 5: Moisture is better than the standard product 4: Slightly better than the standard product 3: Equivalent to the standard product 2: Slightly less moisture than the standard product 1: Standard Less moisture than product

(B) Occlusion feeling on skin 5: Less occlusion feeling than standard product 4: Slight occlusion feeling than standard product 3: Same as standard product 2: Slight occlusion feeling than standard product 1: From standard product There is a feeling of obstruction

[0064]

[Table 1]

Comparative Examples 4 to 6 and Examples 5 to 8 (rinse): Compositions shown in Table 2 below (indicated by component weight%, total amount 1)
00%) is prepared by a conventional method, and a specialized panel 1
After washing the hair with a commercially available shampoo to 0 persons, these rinses were used, (a) moisture when dried, and (b)
A sensory evaluation was performed on the smoothness of the washing. The results are also shown in the table.

The sensory evaluation was performed by using Comparative Example 4 as a standard product and calculating an average value based on the following criteria. Average value is 5.0-
The case of 3.5 was judged as very good (◎), the case of 3.5 to 2.5 was judged as normal (○), and the case of 2.5 to 1.0 was judged as bad (△).

(A) Moisture when dried 5: Moisture is better than the standard product 4: Moisture is slightly better than the standard product 3: Equivalent to the standard product 2: Slightly less moisture than the standard product 1: No moisture is better than the standard product

(B) Smoothness during washing 5: Smoothness than standard product 4: Smoothness than standard product 3: Same as standard product 2: Smoothness than standard product 1: Standard product Less smooth

[0069]

[Table 2]

Examples 9 to 32: The following Tables 3 to 9 show examples of the formulations of milky lotion, hair treatment, body shampoo, lipstick, nail treatment, hair restorer and cleansing cream.

[0071]

[Table 3]

[0072]

[Table 4]

[0073]

[Table 5]

[0074]

[Table 6]

[0075]

[Table 7]

[0076]

[Table 8]

[0077]

[Table 9]

[0078]

According to the present invention, moisture is imparted to the skin, the moisture permeability is high, and it does not give a feeling of blockage. Also, not only the moisture in the hair when dry, but also the smoothness in the rinse off In this respect, an excellent cosmetic can be easily provided.

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat ゛ (Reference) A61K 7/48 A61K 7/48 7/50 7/50 (72) Inventor Masako Koyama Kawasaki-ku, Kawasaki-shi, Kanagawa 1-1 Suzukicho Ajinomoto Co., Inc.Amino Science Laboratory F-term (reference) 4C083 AA112 AA122 AB032 AB242 AB442 AC012 AC022 AC072 AC122 AC132 AC182 AC242 AC302 AC352 AC392 AC402 AC422 AC432 AC442 AC482 AC532 AC582 AC612 AC661 AC662 AC682 AC692 AC782 AC7922 AD7922 AD052 AD092 AD112 AD162 AD202 AD312 AD332 AD512 AD552 AD632 AD662 CC01 CC05 CC13 CC23 CC28 CC33 CC37 CC39 DD31 EE06 EE12 EE22 EE28

Claims (6)

[Claims] 1. An ester of an N-long-chain acyl-neutral amino acid having a straight-chain or branched-chain saturated or unsaturated acyl group having 6 to 22 carbon atoms, the hydrocarbon group constituting the alcohol moiety thereof Is a linear or branched saturated or unsaturated hydrocarbon group having 1 to 10 carbon atoms, an N-long-chain acyl neutral amino acid ester (component A) or / and a linear chain having 6 to 22 carbon atoms. Or a N-long-chain acyl acidic amino acid having a saturated or unsaturated branched-chain acyl group, wherein the hydrocarbon group constituting the alcohol moiety is a straight-chain or branched-chain saturated amino acid having 1 to 10 carbon atoms. A cosmetic composition comprising an N-long-chain acyl acidic amino acid diester (component B) and a wetting agent (component C), which are unsaturated hydrocarbon groups, as active ingredients. 2. The method according to claim 1, wherein the N-long-chain acyl neutral amino acid ester is
Characterized by being represented by the general formula (1)
The cosmetic composition according to claim 1. Embedded image(Where R¹Is a straight or branched chain having 5 to 21 carbon atoms
An alkyl or alkenyl group is represented by R²Is a hydrogen atom or charcoal
A linear or branched alkyl group having 1 to 3 atoms is represented by R³
Is a hydrogen atom or a straight or branched chain having 1 to 4 carbon atoms.
Alkyl group to R ⁴Is a branched or straight chain having 1 to 10 carbon atoms
A chain alkyl or alkenyl group and m is from 0 to 2
Indicates an integer. ) 3. The cosmetic composition according to claim 1, wherein the N-long-chain acyl acidic amino acid diester is represented by the following general formula (2). Embedded image (Wherein, R ⁵ is a branched or straight-chain alkyl or alkenyl group having ^{5 to} 21 carbon atoms, and R ⁶ and R ⁷ are each independently a straight-chain or / and branched chain having 1 to 10 carbon atoms. Represents an alkyl group or an alkenyl group, and n represents an integer of 0 or 1.) 4. The neutral amino acid constituting the N-long-chain acyl neutral amino acid ester is a neutral amino acid selected from sarcosine, alanine, glycine and N-methyl-β-alanine. The cosmetic composition according to any one of claims 1 to 3, wherein 5. The cosmetic composition according to claim 1, wherein the alcohol moiety of the N-long-chain acyl neutral amino acid ester is an isopropyl group. 6. The method according to claim 1, wherein the acyl group of the N-long-chain acyl neutral amino acid ester is a lauroyl group.
The cosmetic composition according to any one of claims 1 to 5, wherein