JP2000217804A - Lancet-integrated measuring device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To improve portability and operability, and surely measure by providing an opening of a lancet part with an aspirating needle, disposing a sensor in the vicinity of the opening part, and operating a presser to drive the aspirating needle and move the sensor, thereby feeding a tested body. SOLUTION: A switching plate 21 is formed in a semicircular structure, and constituted to be turned in a 180-degree arc at every pushing operation by the rotation of the knob and pushing. The pressing force of a presser 23 is transmitted to the switching plate 21 through a pressing rod 28. At the time of a first push, the switching plate 21 is located in a position for pressing an aspirating needle 25 to press the aspirating needle 25, thereby aspirating the skin through an opening part 24. By a second push, the switching plate 21 is switched to a position for pressing a sensor 29, thereby moving the sensor 29 to the opening part 24 to be stationary in a position coming into contact with the body fluid drawn by the aspirating needle 25. By this arrangement, measurement can be surely made.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a measuring device for measuring a specific component contained in a sample, such as a blood glucose concentration (hereinafter referred to as "blood glucose level"), and a lancet-integrated measuring device provided with a lancet. .

[0002]

2. Description of the Related Art The measuring apparatus used in the present invention has various uses such as medical science and sports science, but an example of sample measurement is self-measurement of blood glucose level by a diabetic patient. For the treatment of diabetes, it is necessary to maintain the blood sugar level of a patient in a normal range, and the blood sugar level management by the patient is an important treatment. In particular, when the blood glucose level is maintained in a normal range by the injection of insulin by the patient himself, proper measurement of the blood glucose level by the patient himself is indispensable.

A portable blood glucose measuring device used for such a purpose is already commercially available, and an example thereof is disclosed in, for example, Japanese Patent Publication No. 8-20412. This blood glucose measurement device is used by inserting a disposable sensor having an enzyme electrode into a main body. By supplying blood, which is a specimen, to the sensor using capillary action, an anodic current is generated through an enzymatic reaction and an electrochemical reaction. This anode current is converted into a blood glucose level in the apparatus main body and displayed.

[0004] In the case of the blood sugar level measurement by the patient himself, the patient generally supplies the sample using an instrument called a lancet as disclosed in Japanese Patent Application Laid-Open No. 9-266898, for example. . This lancet is a device for attaching a puncture needle and for making a small hole in the skin such as the fingertip of a patient. By supplying a sample to the above-mentioned sensor from the hole thus made, the blood glucose level can be relatively easily measured. Self-measurements can be made. Supply in this case refers to an act of attaching a sample at a fingertip or the like to the sample inlet of the sensor. In such a measuring method, a set of measuring instruments consisting of several points, such as a blood sugar level measuring device, a lancet, a puncture needle, and a sensor, is carried in a portable device, and the measurement is performed by combining them when necessary.

FIG. 1 is an exploded perspective view showing a conventional example of a blood sugar level measuring sensor. A silver paste is printed on the insulating substrate 1 by screen printing to form leads 2 and 3, and then an electrode system including the measuring electrode 4 and the counter electrode 5 is formed using a conductive carbon paste containing a resin binder. It is formed by printing. Subsequently, an insulating layer 6 made of an insulating paste is formed by printing. On the measuring electrode 4 and the counter electrode 5, a reagent layer 7 made of glucose oxidase as an enzyme, potassium ferricyanide or the like as an electron acceptor is formed. Then, a cover 9 having an air hole 11 is interposed via a spacer 8 having a sample supply hole 10.
It is a configuration covered with. At the time of measurement, when a sample is spotted on one end of the capillary formed by the sample supply hole 10 of the spacer 8, the sample is supplied into the capillary having the other end as the air hole 11, and the reagent dissolves to cause an oxidation-reduction reaction. . At this time, when a voltage is applied to the measurement electrode 4 and the counter electrode 5 through the leads 2 and 3, an oxidation current proportional to the glucose concentration is generated. This oxidation current is converted into a blood glucose level in the apparatus main body and displayed.

FIGS. 2 and 3 show a conventional example of a lancet for attaching and detaching a disposable puncture needle.
The lancet 12 can replace the puncture needle 14 inside the case 13 for each measurement. The puncture needle 14 protrudes from a needle firing port 16 provided at the distal end of the case 13 by a spring member 15. The patient selects a fingertip or an earlobe, and punctures the puncture needle 14 therein to collect blood. FIG.
Shows a state in which the spring member 15 is compressed and the puncture needle 14 is prepared for blood collection. FIG. 3 shows a state in which the spring member 15 in the compressed state is released, and the puncture needle 14 is projected from the needle firing port 16 to pierce the blood collection site. In this case, the puncture needle 14 protrudes from the needle firing port 16 by the spring member 15 released from the compressive force, and the protruding operation is regulated by the stopper 17 provided on the puncture needle 14 side and the stopper receiving member 18 provided on the main body case 13. It has a structure to do.

[0007]

In the above-described conventional blood glucose measurement system, the patient, who is the subject, must always carry two instruments, a lancet and a blood glucose measurement device, as a set. The operation method also requires long training, and it takes a considerable amount of time before a reliable measurement can be performed by the patient himself. In addition, it is difficult for even a skilled person to measure at sites other than the fingertips and forearms (abdominal wall, earlobe, etc.). Also, in recent years, there has been developed a sensor capable of measuring a sample volume of 1 μL or less in order to supply a less invasive sample with less pain. In such a very small amount, a sensor can be accurately supplied to the sensor. The task becomes very difficult. As a result, there is a disadvantage that the measurement fails, and the patient who is the subject has to puncture again, replace the sensor, and perform the measurement again. The present invention has been devised in view of such drawbacks, and has as its object to provide a measuring apparatus which is excellent in portability, easy to operate, and can reliably measure without failure.

[0008]

According to the present invention, a puncture needle is located at an opening of a lancet section for supplying a specimen, and a sensor is located near the opening.
This is a lancet-integrated measuring device including a mechanism in which a puncture needle is driven by a first pushing means of a pressing body, and a sensor is moved by a second pushing means of the pressing body to supply a specimen. Further, the lancet portion has a puncture needle firing mechanism for moving the puncture needle at a predetermined distance, a sensor moving mechanism for moving the sensor, and a mechanism for switching the puncture needle to project and move the sensor. This is a lancet-integrated measuring device that can be performed with at least one pressing body.

[0009]

DESCRIPTION OF THE PREFERRED EMBODIMENTS A lancet-integrated measuring device according to an embodiment of the present invention will be described with reference to the drawings.

(Embodiment 1) FIG. 4 is an overall view of the lancet-integrated measuring device in a measurement standby state, as seen through the inside of a lancet portion. The lancet part is a spring member 27
The puncturing section 19 and the sensor holding section 20 having the puncturing section are held in parallel.
0 switching plate 21 is provided. The lancet-integrated measuring device main body includes an electronic control device that calculates the concentration of the sample based on the signal detected by the sensor 29, and the display unit 22 that displays the calculated concentration of the specific substance is provided. Is provided. Further, a pressing body 23 for driving the puncturing section 19 and the sensor holding section 20 is provided on the upper part of the lancet-integrated body fluid measuring device main body. The opening 24 is set in accordance with the driving position of the puncture needle 25. The puncture section 19 is constituted by a puncture needle 25, a support rod 26 and a spring member 27,
Is a push of the pressing body 23, which can be moved up and down in the spring member 27 by the driving force transmitted from the pressing rod 28 to the switching plate 21. The push in this case refers to the act of pushing the pressing body 23 installed on the lancet-integrated measuring device main body. The sensor holding part 20 is constituted by a socket part 30 and a hollow tube 31, and can move up and down similarly to the support rod 26. Further, the lancet portion main body has a cap shape, and is detachable when the puncture needle 25 and the sensor 29 are replaced.

FIG. 5 shows the sensor 29, the socket 30,
It is an enlarged view of 31 of a hollow tube. The sensor 29 can be connected by inserting it into the socket 30. Thereby, the sensor 29 can be used in a disposable type. A lead wire 32 is drawn from the socket portion 30 through a hollow tube 31. The hollow tube 31 is made of a flexible resin so that the sensor can be moved to the opening 24 along the wall surface of the lancet body. Preferably, polystyrene resin, polyester resin,
A tube made of a polyamide resin, a vinyl chloride resin, a silicone resin, or the like can be used. Further, it is preferable that the lead wire 32 drawn through the inside of the hollow tube 31 is also flexible.

FIG. 6 is an exploded view of a mechanism for switching between the puncturing section 19 and the sensor section 20. For clarity, the structure is shown separately. The knob 41a is provided with an inclined portion 41b, and a semi-circular switching plate 21 is provided via a rotating body 41c having a projecting portion 41d having an inclination.
It is connected to. Inclined portion 41b installed on knob 41a
Fits with the inclined protrusion 41d on the rotating body 41c and moves along the inclined protrusion 41d to rotate the rotating body 41c. By this rotation, the switching between the puncture needle 25 and the sensor unit 20 can be performed by rotating the switching plate 21 connected to the rotating body 41c. At this time, the switching plate 21 has a semi-circular plate-like structure, and the switching plate 21 is rotated by 180 degrees for each push.
° rotate.

FIG. 7 is an exploded view of the lancet portion at the time of the first push of the pressing body. The first push in this case is
It refers to the first act of pushing the pressing body 23 during sample measurement. When the pressing body 23 is pushed, the driving force transmitted from the pressing rod 28 to the switching plate 21 is transmitted only to the support rod 26 on which the puncture needle 25 is mounted, and the puncture needle 25 passes through the opening 24 and punctures the skin. . After puncturing, the spring member 2
7 can return to the original position. As the spring member 27, a compression coil spring made of metal or resin can be used, but is not particularly limited as long as it is an elastic body.

FIG. 8 is an exploded view of the lancet portion when the pressing body 23 is pushed second. The second push in this case refers to an act of pushing the pressing body 23 for the second time in measuring the sample. By pushing the pressing body 23, the pressing rod 2
The driving force transmitted to the switching plate 21 from the switch 8 is the sensor 2
9, the sensor 29 can be moved to the opening 24 along the wall of the lancet body by the flexible material of the hollow tube 31. Since the spring member 27 is not mounted on the hollow tube 31, the sensor 29 can be stopped at an arbitrary position of the opening 24. At this time, the opening 2 that can come into contact with an arbitrary amount of bodily fluid 33 discharged from the skin by the puncture needle 25
It is preferable to set the length of the hollow tube 31 so that the sensor 29 can be stopped at the position 4. Further, the sensor 29
A stopper can be provided so that the can be fixed at a predetermined position. In this way, the discharged body fluid can be sucked by the sensor 29 to start the measurement.

After the measurement, the cap 40 is removed, and the puncture needle 25 and the sensor 29 are removed. Holding the socket 30, the sensor holding unit 20 is pushed upward to bring it to the same position as in the measurement standby state. At this time, the switching plate 21, the pressing rod 28, and the pressing body 23 are also pushed upward with the pushing of the sensor holding unit. Continue with cap 40
Attach and store. When measuring continuously, puncture needle 2
5 and replace the sensor 29, return to the initial position,
What is necessary is just to put on the cap 40 and make it the standby state of the next measurement.

Embodiment 2 FIG. 9 is an overall view of a lancet-integrated measuring device having two pressing bodies. The pressing body 34 for driving the lancet and the pressing body 35 for moving the sensor are separated. The lancet drive pressing body 34 is connected to an internal support rod 26 connected to the puncture needle 25, and a spring member 27 is mounted around the internal support rod 26. A pressing rod 28 for sensor movement is connected to the pressing body for sensor movement. The sensor unit 20 is provided in front of the pressing rod 28 in parallel with the support rod 26. Further, the lancet drive pressing body 34 and the sensor moving pressing body 35 are provided with a protruding pressing body guide 39 so that they can be distinguished from each other. Thus, it is possible to provide a lancet-integrated measuring device that is easy to use for a measurement person in a dark place and a blind person.

First, the measurer pulls up the lancet drive pressing body 35 upward to prepare the puncture needle 25 for firing. At this time, the internal support rod 26 connected to the puncture needle 25
Is pulled up, the spring member 27 is in a compressed state, and the circular stopper 36 below the support rod is hooked by the hook 37. Subsequently, when the puncture needle firing button 38 provided on the lancet drive pressing body 34 is pressed, the hook 37 is released, and the puncture needle 25 is fired by the repulsive force of the spring member 27,
Puncture the skin to drain body fluids.

Subsequently, the driving force transmitted to the pressing rod 28 by the push operation of the sensor moving pressing body 35 is transmitted to the hollow tube 31 on which the sensor 29 is mounted, and the flexible material of the hollow tube 31 The sensor 29 can be moved to the opening 24 along the wall surface of the lancet body. Since no spring member is attached to the hollow tube 31, the sensor 29 can be stopped at an arbitrary position of the opening 24. At this time, it is preferable to set the length of the hollow tube 31 so that the sensor 29 can be stopped at the position of the opening 24 where the puncture needle 25 can come into contact with an arbitrary amount of bodily fluid discharged from the skin. In this way, the discharged body fluid can be sucked by the sensor 29 to start the measurement. After the measurement is completed, the puncture needle and the sensor may be removed or replaced, and then stored or placed in a standby state for the next measurement, as in (Example 1).

[0019]

According to the lancet-integrated measuring device of the present invention, the portability can be improved, and the measurement can be performed only by pushing the pressing body twice, so that the operability is greatly improved. In addition, since the operation of bringing the sensor into contact with the discharged body fluid can be performed semi-automatically, and the positional accuracy is improved, the failure in supplying the sample is eliminated. As a result, it is not necessary for an inexperienced measurer to repeat the measurement.

[0020]

[Brief description of the drawings]

FIG. 1 is an exploded perspective view of a blood sugar level measurement sensor.

FIG. 2 is a schematic view of a preparation state of a lancet with a detachable blood sampling needle.

FIG. 3 is a schematic view of a lancet with a detachable blood collection needle in a state during blood collection.

FIG. 4 is an overall view of a lancet-integrated measuring device (measurement standby state).

FIG. 5 is an enlarged view of a sensor, a socket, and a hollow tube.

FIG. 6 is an exploded view of a switching mechanism.

FIG. 7 is an exploded view at the time of the first push.

FIG. 8 is an exploded view at the time of the second push.

FIG. 9 is an overall view of a lancet-integrated measuring device having two pressing bodies.

[Explanation of symbols]

 1: Board 2: Lead 3: Lead 4: Measurement electrode 5: Counter electrode 6: Insulating layer 7: Reagent layer 8: Spacer 9: Cover 10: Sample supply hole 11: Air hole 12: Lancet 13: Case 14: Puncture needle 15 : Spring member 16: Needle firing port 17: Stopper 18: Stopper receiving 19: Puncturing part 20: Sensor holding part 21: Switching plate 22: Display part 23: Pressing body 24: Opening part 25: Puncture needle 26: Support rod 27: Spring member 28: Press rod 29: Sensor 30: Socket part 31: Hollow tube 32: Lead wire 33: Body fluid 34: Puncture needle driving press body 35: Sensor moving press body 36: Circular stopper 37: Hook 38: Puncture Needle firing button 39: Pressing body guide 40: Cap 41a: Knob 41b: Inclined section 41c: Rotating body 41d: Inclined projection

Claims (2)

[Claims] 1. A puncture needle is located at an opening of a lancet section for supplying a specimen, and a sensor is located near the opening.
A lancet-integrated measuring device comprising a mechanism in which a puncture needle is driven by a first pushing means of a pressing body and a sensor is moved by a second pushing means of the pressing body to supply a sample. 2. The lancet section has a puncture needle firing mechanism for projecting the puncture needle at a predetermined distance, a sensor moving mechanism for moving the sensor, and a mechanism for switching between puncture needle projection and sensor movement. The lancet-integrated measuring device according to claim 1, wherein the moving operation can be performed by at least one pressing body.