JP2000212038A - Selection of cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To objectively and readily select a proper cosmetic while avoiding trouble by using the beautifulness of skin and the sensitivity of the skin as indices. SOLUTION: A cosmetic (preferably a basic cosmetic) is selected by using the beautifulness of skin and sensitivity of the skin as indices. The above beautifulness of the skin is indicated by the nonuniformity of skin color and the skin form. The nonuniformity of the skin color is preferably the existing state of melanin and/or the irregular color and the existing state of the melanin is preferably indicated by the amount of the existing melanin in keratinocytes and the nonuniformity of the existence in the keratinocytes. The irregular color is evaluated by using irregular color models prepared by computer morphing and comparing the irregular color models with an irregular color model photograph. The evaluation weighting ratio as the indices is preferably 0.6-0.8 for 0.2-0.4 existing state of the melanin. Furthermore, the skin form is preferably evaluated by using the disturbance (preferably discriminated by the presence or absence of directionality) in the texture of facial skin (the skin between the corners of the eyes and cheeks) as the index and further using especially a replica specimen.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a method for selecting a cosmetic, which is suitable for selecting a basic cosmetic.

[0002]

2. Description of the Related Art Today, basic cosmetics are remarkably differentiated and developed according to their functions based on various effects. For example, cosmetics for clearing skin texture, cosmetics for improving moisturizing ability, Cosmetics that suppress the generation of pigments such as melanin and make the color white and beautiful, cosmetics that suppress and improve the formation of wrinkles,
Many cosmetics and the like having a combined effect of these effects are sold on the market. What is specified by function is certainly easy to understand and easy to select, but if you can not accurately recognize what kind of trouble your skin actually has, it fits your skin You can not choose a cosmetic that has been done. Accurate recognition of such troubles is very difficult. Because, for example, if you discover that there are wrinkles etc. that are very worrisome, and you realize that your worst trouble is wrinkles, if you actually carry out objective observation, abnormalities such as melanin This is because it is not unusual for a situation in which the trouble of the pigment abnormality caused by the dye is more serious. That is, there is nothing less reliant on the subjective grasp of the trouble. That is, a means for selecting an accurate and objectively suitable cosmetic has been desired.

[0003] In addition, as there is a word saying that white color is difficult to hide, maintaining a beautiful white skin is something that every woman wants and does not stop. For this reason, various whitening materials for cosmetics have been developed. As such whitening materials, for example, ascorbic acid and its derivatives, glutathione and its derivatives, hydroquinone and its derivatives, and various herbal extracts have been developed. In addition, a number of steps have been found as a mechanism for darkening the skin color, and it is also known that there are many mechanisms called inhibition of melanin production in a bite. Because of this,
There are now a huge number of types of whitening cosmetics. Therefore, those who are going to use the whitening cosmetics are often confused to select which whitening cosmetics are suitable for themselves. That is, there has been a demand for a means for selecting a whitening cosmetic suitable for an individual. Further, the degree of the dye trouble is often subjectively judged by visual observation, but at present, there is no known method for objectively discriminating the degree.

[0004] In addition, when selecting cosmetics,
In recent years, due to various kinds of rapidly increasing stress, deterioration of environment, and the like, the number of people with so-called sensitive skin, which responds delicately to even a slight stimulus, has significantly increased. Even if you choose an appropriate cosmetic that focuses on beautiful skin in order to make the skin beautiful as described above, people with such sensitive skin are merely irritants and may cause inflammation etc. There has been a demand for a method of selecting cosmetics that takes into account the safety derived from such skin sensitivity. In addition, although it has already been performed to select a cosmetic based on sensitive skin as a selection criterion, it has never been performed to combine this element with a beautiful skin element as an index. Also, it has not been known at all that adding such a factor can realize safe and beautiful skin.

[0005] On the other hand, it has never been known that color unevenness and the presence of melanin at the application site are factors as characteristics of a user for selecting an appropriate whitening cosmetic. Therefore, it has not been known at all that it is possible to select a whitening cosmetic suitable for an individual by using such parameters.

[0006] Furthermore, it is already known that there are various causes of skin morphological changes represented by wrinkles and skin firmness. For example, the formation of wrinkles is a particularly serious problem for many women, since the negative effects on their appearance are so great. For this reason, various cosmetics for preventing wrinkles have been developed. Such cosmetics include, for example, cosmetics that contain a coating component, physically expand wrinkles and make them less noticeable, and impart moisture to wrinkles by imparting a moisturizing function to make them less noticeable. Promotes skin surface turnover,
Cosmetics that make wrinkles less noticeable have been developed one after another. In recent years, it has been revealed that the collapse of the collagen fiber bundle structure plays a major role in the formation of wrinkles, and such a fiber bundle structure is reconstructed.
Ursolic acid derivatives and the like have been found, and great progress has been made in wrinkle control. In such a situation, what is important is to perform a treatment suitable for the situation from the beginning of the wrinkle formation process, and a technique for accurately knowing the wrinkle formation process has been desired. This is because in situations where wrinkles have not yet been formed and the fiber bundle structure has not collapsed, treatment with a fiber bundle remodeling agent is not necessary, and in very early wrinkle formation conditions, administration of moisturizing components is sufficient. This is because the effect can be enhanced, and the dose and administration method of the fiber bundle remodeling agent, the selection of the treatment agent to be performed at the same time, and the like differ depending on the wrinkle formation state. In other words, it has to be said that there is no selection standard for an appropriate countermeasure against such a change in skin morphology.

[0007]

SUMMARY OF THE INVENTION The present invention has been made under such circumstances, and it is an object of the present invention to provide a method for objectively and easily selecting an appropriate cosmetic while avoiding a trouble. I do.

[0008]

In view of such circumstances, the present inventors have sought a method of objectively and easily selecting an appropriate cosmetic that can avoid troubles, and as a result of intensive research efforts, The inventors have found that such selection can be made by using as an index the sensitivity of the skin distinguished by the shape of keratinocytes and the like, the unevenness of the skin color, and the beautiful skin element distinguished by the skin morphology. Was completed. Hereinafter, the present invention will be described in detail focusing on embodiments.

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION <1> Uneven skin color which is an index of skin beauty in the selection method of the present invention is characterized by using skin beauty as an index. . Various indicators of skin beauty are known, and any of them can be used in the present invention. However, in the present invention, an axis discriminated using uneven skin color and skin morphology as indicators. It is preferable to use Among these, there are various ways of understanding the unevenness of the skin color, but in the present invention, any manner of showing the unevenness of the skin can be used without particular limitation as long as it represents unevenness of the skin. Preferable examples include the presence state of melanin on a microscopic scale, and uneven color of a face on a macroscopic scale. These can be used alone as indices, but it is preferable that the indices are obtained by converting micro-macro into complementary values. Less than,
These embodiments will be described.

(1) Existence of melanin in the stratum corneum Melanin is a pigment present in epidermal tissue, but its form is variously different. For comparison of melanin having various existing forms, for example, it is preferable to perform the following criterion, since a considerably ecologically suitable classification can be performed. That is, when classifying the state of presence of melanin, two axes of non-uniformity using the abundance of the melanin in keratinocytes and the variation in the presence as an index are used. Many methods have already been known for such a melanin presence state, and any of these methods may be used. However, the most preferred method is a method devised by the present inventors, in which keratinocytes are collected on an adhesive disk, transferred to a transparent adhesive tape, and stained with silver nitrate and gentian violet. In other words, the collected sample is 0.5%
Aqueous ammonia was added dropwise to an aqueous silver nitrate solution, and the mixture was treated with a silver staining solution adjusted to pH 10 at 45 ° C. for 10 minutes to perform silver staining, then washed three times with water and treated with a 0.15% gentian violet solution for 10 minutes. In this method, the specimen is washed with water, dried, poured with a transparent silicone agent so as to cover the stained portion, placed on a cover glass to form a sample, and observed under a microscope. Since the sensitivity of skin such as sensitive skin can be discriminated from the specimen prepared by this method as described later, it is preferable to discriminate the presence state of melanin by this method. The abundance of melanin and the heterogeneity of its presence, which are measured in this way, have a great influence on the observation impression of the state of melanin, and the relationship is independent. In other words, the greater the abundance of melanin and the greater the non-uniformity, the more the skin is separated from the beautiful skin, and it is necessary to use multiple whitening mechanisms by whitening substances. The less the skin becomes, the more beautiful the skin becomes and the less the whitening effect of the whitening cosmetic becomes. That is,
The melanin state can be used as an index by uniaxializing the abundance and heterogeneity of melanin in the stratum corneum using a box model. It is very preferable to use this because it is easy to make a determination, but it is also within the technical scope of the present invention to uniaxialize the presence state of melanin by another method and use it as an index. FIG. 1 shows an example of the box-shaped model axis. As can be seen from this example, the presence of melanin can be clearly distinguished on this axis.

(2) Color Unevenness In the method of selecting a cosmetic according to the present invention, as a factor for discriminating the non-uniformity of the color of the beauty component of the skin, in addition to the above-mentioned state of melanin, the unevenness of the color of the skin is determined. The degree can be used as an index. Skin color unevenness is also caused by abnormal production of melanin, as well as poor presence of melanin, and is a skin problem that should be corrected by cosmetics such as whitening cosmetics, and only when both are improved It can be the basis for really beautiful white skin. The presence state of these melanin and the color unevenness are independent of each other, and each of them alone is a factor for an appropriate whitening effect. By combining these two, a more appropriate whitening cosmetic can be selected. This is because the melanin of the stratum corneum is mainly microscopic, and there is a background element, whereas the color unevenness is more macroscopic, so its contribution to the appropriate whitening effect is large. . As shown in the examples below, when this is subjected to multivariate analysis by tests,
The weighting ratio is 0.6 to 0.8 for color unevenness with respect to the presence state of melanin of 0.2 to 0.4. Using this weight,
Setting an axis for an appropriate whitening effect will be a criteria for selecting an excellent whitening cosmetic. Here, the evaluation of color unevenness is performed by capturing the face state as an image in a computer, applying processing such as binarization, calculating its distribution, or using a computer morphing method. By creating some standard uneven faces, comparing them to this standard face, and discriminating the degree,
It can be expressed as a numerical value. Even if this numerical value is calculated by comparison with a standard face with the naked eye, its reproducibility is extremely good and can be used as an objective numerical value. FIG. 2 shows an example of a standard face having such color unevenness. Table 1 below shows the results of using the standard face to determine the color unevenness of the face of three randomly selected panelists by three observers. This shows that the reproducibility is high even with such a discriminating means. Therefore, for simplicity,
It is preferable that color unevenness is discriminated by such a method and used as an index.

[0012]

[Table 1]

(3) Index of color non-uniformity In the method of selecting a cosmetic according to the present invention, the color non-uniformity axis is a function of the presence of melanin in the keratinocytes of the skin and the color unevenness. It is characterized by a preferred form. As described below, the relationship between beautiful skin, the presence of melanin, and uneven color is (skin beauty) = 0.253 × (existence of melanin in keratinocytes) + 0.936 × (skin unevenness of skin) ) + 1.354. That is,
As can be seen from this formula, it is also understood how much the non-uniform value of the color is necessary for the formation of the beautiful skin of the person, and by improving the presence state of melanin and reducing the unevenness of the skin color, It can also be seen that the beautiful skin value can be raised.
That is, to what extent the person needs to improve the objection off uniformity, and also, a person who intends to use a whitening cosmetic, calculates this beautiful skin value from the presence state of melanin and uneven skin color, It can be seen that if the value is small, a cosmetic having a higher whitening effect is selected, and if the skin value is large, a cosmetic having no whitening effect is selected. This is an important indicator for cosmetic selection.

(Statistical processing example) Using 334 female panelists (ages 16 to 71) randomly selected, keratinocytes were collected from the right cheek by the adhesive disk method, transferred to an adhesive tape, and transferred to an adhesive tape. Aqueous ammonia was added dropwise to a 0.5% aqueous solution of silver nitrate to adjust the pH to 10, and a silver stain was used.
℃ 10 minutes, silver-stained, washed 3 times with water, 0.15%
Treated with gentian violet solution for 10 minutes. This specimen was washed with water, dried, poured with a transparent silicone agent so as to cover the stained portion, placed on a cover glass to form a sample, observed under a microscope, and determined the presence state of melanin from 1 (bad) to 1 according to the criteria shown in FIG. A rating of 5 (good) was given for evaluation. Further, using a specialized panel, a standard face of the color unevenness shown in FIG. 2 created by morphing was used to evaluate the state of the unevenness by assigning a score of 1 (bad) to 5 (good). In addition, the overall beauty of the skin was evaluated with a score of 1 (not beautiful) to 5 (beautiful). When these were subjected to multiple regression analysis, a multiple correlation coefficient of 0.6617 (skin beauty) = 0.253 × (the presence of melanin in the keratinocytes) + 0.936 × (skin color unevenness) +1. 35
It turns out that it returns to the formula written in 4. At this time, the standard regression coefficient was 0.198 for the presence of melanin in the keratinocytes and 0.590 for the color unevenness. That is, the weighting ratio varies from 0.6 to 0.8 in color unevenness with respect to the presence state of melanin in 0.2 to 0.4. When the color tone smoothness and skin beauty calculated according to the contribution ratio are plotted, (skin beauty) = 0.8 as shown in FIG.
Regression is made to a linear formula of 961 × (color tone smoothness) +1.5095.

[0015]

[Table 2]

<2> Skin form as an element of skin beauty according to the selection method of the present invention In skin beauty according to the method of selecting a cosmetic according to the present invention, skin form is also used as an index. Examples of the skin morphology include microscopic texture disturbance and macroscopic wrinkle formation, and these may be used alone or in combination. It is preferable to use an index that captures the texture of micro skin as a wave function. Such an index is a value that predicts wrinkle formation that will come in the future, and is preferably included as an index because precautionary measures are enhanced. Moreover, since this value can be measured from the replica,
It has the advantage that skin morphology can be evaluated without including personal feeling. Of course, a combination of micro-macro can be used as an index, and more accurate judgment can be made in this manner. As a comprehensive index, macro 0.2-0.3
It is preferable to comprehensively convert with a weight ratio of 0.3 to 0.6 with respect to. Hereinafter, embodiments of the skin morphology index will be described.

(1) Method of Differentiating Wrinkle Formation The method of determining wrinkle formation, which is an indicator of the present invention, is characterized by using disorder of facial skin texture as an index. Here, the disturbance of the texture of the skin can be roughly observed and determined with the naked eye, but more precisely, a replica specimen or a stereoscopic microscope or a micro video image is taken into an image processing device and the like, and 5 to 20 times. It is preferable that the determination is made by enlarging at a magnification and comparing with standard skin or the like. Among these means, it is preferable to use a replica because a specimen can be easily prepared without using a large-scale device. The replica may be made according to a known method, and a plastic plate such as a commercially available replica kit is softened with a solvent or the like, and this is pressed on the skin, and the shape of the skin is copied as an unevenness of the plastic plate. Good. Also, as a position where such a replica is collected, the skin between the outer corner of the eye and the cheek is particularly preferable. This is because the texture of the skin at this position is more closely related to wrinkle formation. The texture of the original skin can be known by observing the replica specimen obtained for this purpose with a microscope or the like. The state of the texture is uniformly distributed in the vertical and horizontal grooves is a good texture, and a deep groove in one direction is distinguished from the poor texture. If discrimination is performed from this viewpoint, the possibility of wrinkle formation can be accurately and simply determined. Such a texture can be converted into a continuous numerical value by preparing a standard sample in advance and determining it as a numerical value. The same procedure may be applied to video images and observation with a stereoscopic microscope. The disorder of the skin texture thus identified is closely related to future wrinkle formation, as shown in the examples described later, and if appropriate measures are not taken, this disorder will shift to wrinkle formation. Such wrinkle formation possibility is from 5 (very rough texture and high possibility of wrinkle formation) to 5 (very textured and low wrinkle formation possibility) according to the texture of the skin. It is preferable for convenience to divide into stages. This value is temporarily referred to as a "smoothness" value.

(2) Differentiation method of wrinkle formation state The wrinkle formation state, which is one of the factors representing the skin morphology, which is an index of the selection method of the present invention, can be obtained by observing the face macroscopically. By forming a standard wrinkle model by morphing and comparing the wrinkle formation state with the standard wrinkle model, the degree of wrinkle formation can be more objectively observed and determined. FIG. 4 shows an example of a standard wrinkle model serving as this reference. In particular, it is preferable and accurate to perform such discrimination at the outer corner of the eye. This value is temporarily referred to as a smooth outer corner value.

(3) Method of selecting cosmetics for skin morphology The method of selecting cosmetics for skin morphology accurately discriminates wrinkle formation processes, selects cosmetics suitable for the stage, and improves wrinkle formation. Is to prevent. As a wrinkle index, as shown in the following statistical processing example 2, the relationship between the beautiful skin value and these values is (beautiful skin value) = 0.448 × (smooth smooth tone value) + 0.254 × (eye corner smooth tone value) ) +1.124 is regressed with a multiple regression coefficient of 0.832. That is, the value obtained by substituting the firmness smoothness value and the corner of the eye smoothness value into this equation is the representative value of the skin morphology. In the stage with a low possibility of wrinkle formation, treatment such as administration of a moisturizing component such as a heparin-like substance is performed, and as the stage goes up, not only the moisturizing component but also vitamin A acids, phytosteside, phytosterol, sphingosine and Administer a turnover promoting component such as a steroid, a stratum corneum detachment promoting agent such as α-hydroxy acid, a collagen synthesis promoting agent such as bacgancon extract, a collagen fiber bundle restructuring agent such as rosemary extract or ursolic acid derivative, etc. It is characterized by treating and improving or preventing wrinkles. Examples of the standard cosmetics for the five stages of the wrinkle formation possibility include those shown in Table 3 below.

[0020]

[Table 3]

(Statistical processing example 2) Using 334 female panelists (age 16 to 71 years old) randomly selected, the wrinkle state of the right outer corner of the eyes was rated 1 (bad) to 5 (good). Was evaluated. Further, a parallel light beam was applied obliquely at an angle of 45 degrees to a replica collected from the skin between the eyes and the cheek, and the waveform of the interval between the shadows generated thereby was determined. From the uniformity of the cycle and the magnitude of the amplitude, this waveform is expressed as 1 (the periodicity is large, the amplitude is small and the texture is disturbed) to 5 (the periodicity is uniform, the amplitude is large, and the texture is adjusted). ). In addition, the overall beauty of the skin was evaluated with a score of 1 (not beautiful) to 5 (beautiful). When these were subjected to multiple regression analysis, a multiple correlation coefficient of 0.832 (beautiful skin value) = 0.448 × (smooth tone value) +0.254
X (normal value of the outer corner of the eye) + 1.124.

<3> Skin Sensitivity as an Index of the Selection Method of the Present Invention By selecting a cosmetic according to the above selection criteria, a normal person can select a cosmetic that embodies beautiful skin without any problem. However, for those with sensitive skin who have increased sensitivity to skin irritation, which is rapidly increasing in modern times, when choosing cosmetics from the viewpoint of beautiful skin, skin troubles may occur. May occur. That is, by avoiding such danger, it is possible to select a more effective and safe cosmetic. The most important issue in this regard is how to incorporate the sensitive skin factor into the selection criteria of the cosmetics at what weighting ratio. In other words, how sensitive the skin is to be classified. The present inventors investigated the actual condition of sensitive skin for 152 cosmetics users, and found that the frequency was extremely high.
By classifying sensitive skin that is susceptible to hypersensitivity reactions such as inflammatory reactions to various stimuli, less frequent, and slightly more sensitive skin only in specific cases, and normal skin that usually does not cause hypersensitivity reactions It has been found that a cosmetic suitable for realizing beautiful skin can be selected while taking sensitivity into account. Regarding the sensitivity of such skin, by the above-mentioned adhesive disc method, the shape of the keratinocytes of the collected specimen is changed in size (the larger the sensitivity, the more sensitive the skin) and the shape (the more the hexagonal shape is broken, the higher the sensitivity). Using the box-shaped model with reference to the sensitive skin), the discrimination can be made by judging on the axis of 1 (large, deformed) to 5 (shape is hexagonal, small and uniform). That is, on this axis, 0-1 is sensitive skin,
3 is slightly sensitive skin, and 4 to 5 can be distinguished from normal skin. In the present invention, it is preferable to use this value as a representative value of skin sensitivity. According to the classification of this value, the above-mentioned investigation results are shown in Table 4. This indicates that it is appropriate to classify the skin into three categories: sensitive skin, slightly sensitive skin, and normal skin. here,
In response to these skin sensitivities, for sensitive skin, it is preferable to avoid using cosmetics containing substances that may cause irritation, and to focus on the moisturizing effect. Cosmetic selection may be made based on uneven color and skin morphology.For slightly sensitive skin, measures that are intermediate between sensitive and normal skin, that is, the color that is less irritating while focusing on the moisturizing effect. A cosmetic containing a uniform improving component and a skin morphology improving component may be selected based on the above-mentioned uneven color and skin morphology.

[0023]

[Table 4]

<4> Method for Selecting Cosmetic of the Present Invention According to the above-mentioned method, the method for selecting the cosmetic according to the present invention discriminates the sensitivity of the skin from the shape of the keratinocytes, and then determines the uneven color and the skin morphology. It is characterized by selecting cosmetics as an index. If the element of the sensitive skin is removed, both the color unevenness and the skin morphology linearly regress to the beautiful skin value as described above. What this means is that beautiful skin is realized only when both are in order. That is, if either of them is significantly impaired, it is difficult to realize beautiful skin no matter how much the other is improved. Therefore, in the present invention, in view of these two aspects, the present invention is characterized as a guide for realizing beautiful skin. There are no particular limitations on the method of evaluating the two axes, as long as both are improved and the beautiful skin value is improved. For example, the beautiful skin value calculated from the color non-uniformity value and the beautiful skin value calculated from the skin morphology Compare the values and choose a cosmetic to treat items with lower beautiful skin values, or a cosmetic that contains a whitening component or skin morphology improving component in the cosmetic so as to be compatible with the ratio of both beautiful skin values. A selection method can be exemplified.
Of these, the former has the advantage of selecting a cosmetic that matches the situation in the case of monitoring in a short period such as one month, and the latter can improve on average without a monitor. There are strengths. Originally, cosmetics are seasonal,
Considering that it has the characteristic of being used by changing the actual usage by adapting to the skin quality, the former usage is more preferable. For slightly sensitive skin, as described above. After suppressing the irritation of the component itself and focusing on the moisturizing effect, it is sufficient to make a selection according to normal skin.

[0025]

The present invention will be described in more detail with reference to the following examples, but it goes without saying that the present invention is not limited to these examples.

<Example 1> Cosmetic product 1 for sensitive skin shown below
One kind of cosmetics for non-uniform color for sensitive skin and one kind of cosmetic for skin morphology for slightly sensitive skin, five kinds of cosmetics for non-uniform color for normal skin and five kinds of cosmetics for normal skin To create
Sensitive skin, slightly sensitive skin, and normal skin are classified according to the shape of the keratinocytes.People with sensitive skin choose cosmetics for sensitive skin, and those with slightly sensitive skin have a beautiful skin value calculated from the regression formula above. Select the corresponding lower-level cosmetics, and for people with normal skin, use the multiple correlation formula above to determine whether color unevenness is more important or skin morphology is more important. The values (non-uniform color) and the beautiful skin value (skin morphology) were compared, and an attempt was made to select a cosmetic suitable for the panel according to the stage of the item with the low beautiful skin value. That is, after using 306 female panelists randomly selected to determine the sensitivity of the skin,
This is divided into three groups so that there is no variation in the sensitivity composition of the skin, and the color tone smoothness, the outer corner smoothness and the firmness smoothness are calculated.
One group calculates a beautiful skin value (uneven color) and a beautiful skin value (skin morphology) for each skin sensitivity, and evaluates the smaller evaluation value as 1 to 2 or less, 2 or more to less than 3 and 3 or more to less than 4 4 or more, less than 5 and 5 or more (the lower the numerical value, the worse the color unevenness and melanin situation). For each, sensitive skin cosmetics, slightly sensitive skin color non-uniform cosmetics, and slightly sensitive skin forms Corresponding cosmetics, cosmetics for normal skin items 1, 2, 3, 4,
5 (selection group of the present invention), and 1 group selects normal skin item corresponding cosmetics 1, 2, 3, 4, 5 for important items according to a regression formula without considering skin sensitivity. (Beauty skin index selection group) The remaining group selected the normal skin / skin morphology-adaptive cosmetic 3 as the morning cosmetic and the normal skin color unevenness-adaptive cosmetic 3 as the night cosmetic for all the panelists. (Control group) Each of these cosmetics was used for 1.5 months, and the cosmetics were selected again in the same manner, and further used for 1.5 months. When troubles such as inflammation occurred, they were immediately discontinued. Before and after use, experts evaluated the beauty skin value by giving a score of 1 (not beautiful) to 5 (beautiful) based on the overall impression. The beautiful skin value before use was subtracted from the beautiful skin value after use to obtain a beautiful skin improvement value, which was averaged for each group to obtain a beautiful skin improvement group average value. This value is
The selection group of the present invention was 1.31, the beautiful skin index selection group was 1.21, and the control group was 0.63. The occurrence of trouble was 0 in the selected group of the present invention, 2 cases in the beautiful skin index selection group, and 5 cases in the control group. This allows
It can be seen that the method for selecting cosmetics of the present invention is more excellent in terms of safety as well as the effect of realizing beautiful skin.

(Cosmetic for sensitive skin; vial form) Glycerin 3 parts by weight 1,3-butanediol 3 parts by weight Kouki extract 0.1 part by weight Birch extract 0.1 part by weight Phosphate buffer salt 0.1 part by weight Water 93 .7 parts by weight

(Cosmetic for color unevenness for slightly sensitive skin) Glycerin 5 parts by weight 1,3-butanediol 5 parts by weight Ethanol 5 parts by weight Kouki extract 0.1 parts by weight Birch extract 0.1 parts by weight Royal jelly 0.1 Parts by weight Bovine placenta extract 0.1 parts by weight Water 84.6 parts by weight

(Cosmetic for skin morphology for slightly sensitive skin) Glycerin 5 parts by weight 1,3-butanediol 5 parts by weight Ethanol 5 parts by weight Kouki extract 0.1 parts by weight Birch extract 0.1 parts by weight Heparin-like substance 0. 1 part by weight Rosemary extract 0.1 part by weight Water 84.6 parts by weight

(Cosmetic for non-uniform color 1; Cosmetic for uneven color stage 1) Glycerin 3 parts by weight 1,3-butanediol 5 parts by weight Ethanol 10 parts by weight Arbutin 0.5 parts by weight Magnesium ascorbate 2 parts by weight 0.1 parts by weight Sour stalk extract 0.3 parts by weight Methyl paraben 0.1 parts by weight Water 81 parts by weight

(Cosmetic for color unevenness 2; Cosmetic for color unevenness stage 2) Glycerin 3 parts by weight 1,3-butanediol 5 parts by weight Ethanol 10 parts by weight Arbutin 0.5 part by weight Royal jelly 0.1 part by weight Parts Sow arbor extract 0.3 parts by weight Methyl paraben 0.1 parts by weight Water 81 parts by weight

(Cosmetic for color unevenness 3; Cosmetic for color unevenness stage 3) Glycerin 3 parts by weight 1,3-butanediol 5 parts by weight Ethanol 10 parts by weight Royal jelly 0.1 part by weight Ascorbic acid 2 magnesium phosphate 0.1 part by weight Sour stalk extract 0.3 part by weight Methyl paraben 0.1 part by weight Water 81.4 parts by weight

(Cosmetic for color unevenness 4; Cosmetic for color unevenness stage 4) Glycerin 3 parts by weight 1,3-butanediol 5 parts by weight Ethanol 10 parts by weight Royal jelly 0.1 part by weight Sohakuhi extract 0.3 Parts by weight methyl paraben 0.1 parts by weight water 81.5 parts by weight

(Cosmetic for Color Non-uniformity 5; Cosmetic for Color Uneven Stage 5) Glycerin 3 parts by weight 1,3-butanediol 5 parts by weight Ethanol 10 parts by weight Royal jelly 0.1 part by weight Sohakuhi extract 0.3 Parts by weight methyl paraben 0.1 parts by weight water 81.5 parts by weight

(Cosmetic for skin morphology 1; Cosmetic for skin texture stage 1) Glycerin 5 parts by weight 1,3-butanediol 5 parts by weight Rosemary extract 0.1 part by weight Bakagacon extract 0.1 part by weight Soy protein 0.1 part by weight Stearyl ursulate 0.1 part by weight Heparin analog 0.1 part by weight Sodium lactate 0.1 part by weight Ethanol 10 parts by weight Methyl paraben 0.1 part by weight Water 79.3 parts by weight

(Cosmetic for Skin Morphology 2; Cosmetic for Skin Texture Stage 2) Glycerin 5 parts by weight 1,3-butanediol 5 parts by weight Rosemary extract 0.1 part by weight Bakugacon extract 0.1 part by weight Soy protein 0.1 parts by weight Stearyl ursulate 0.1 part by weight Heparin analog 0.1 parts by weight Ethanol 10 parts by weight Methyl paraben 0.1 parts by weight Water 79.4 parts by weight

(Cosmetic for skin morphology 3; Cosmetic for skin texture stage 3) Glycerin 5 parts by weight 1,3-butanediol 5 parts by weight Bacacone extract 0.1 part by weight Sodium lactate 0.1 part by weight Soy protein 0 0.1 part by weight Heparin-like substance 0.1 part by weight Ethanol 10 parts by weight Methylparaben 0.1 part by weight Water 79.5 parts by weight

(Cosmetic for skin morphology 4; Cosmetic for skin texture stage 4) Glycerin 5 parts by weight 1,3-butanediol 5 parts by weight Bakgacon extract 0.1 part by weight Soy protein 0.1 part by weight Heparin-like substance 0.1 parts by weight Ethanol 10 parts by weight Methyl paraben 0.1 parts by weight Water 79.6 parts by weight

(Cosmetic for skin morphology 5; cosmetic for skin texture stage 5) Glycerin 5 parts by weight 1,3-butanediol 5 parts by weight Bakugacon extract 0.1 part by weight Soy protein 0.1 part by weight Heparin-like substance 0.1 parts by weight Ethanol 10 parts by weight Methyl paraben 0.1 parts by weight Water 79.6 parts by weight

[0040]

According to the present invention, it is possible to provide a method for objectively and easily selecting an appropriate cosmetic without causing troubles such as inflammation.

[Brief description of the drawings]

FIG. 1 is a diagram showing criteria for the state of melanin.

FIG. 2 is a diagram showing a standard of color unevenness. (Drawing substitute photo)

FIG. 3 is a diagram showing the relationship between skin beauty and color tone smoothness.

FIG. 4 is a diagram showing criteria for forming wrinkles. (Drawing substitute photo)

Continuation of the front page (72) Inventor Yoshikazu Hirai 27-1 Takashimadai, Kanagawa-ku, Yokohama-shi, Kanagawa Prefecture F-term in the POLA Yokohama Research Laboratory 2G020 AA08 DA05 DA16 DA66 4C083 AA072 AA111 AA112 AC102 AC122 AC302 AC352 AC482 AD312 AD392 AD412 AD642 CC03 DD23 EE12 EE50

Claims (16)

[Claims] 1. A method for selecting a cosmetic, characterized by using skin beauty and skin sensitivity as indices. 2. The method for selecting cosmetics according to claim 1, wherein the beauty of the skin is represented by uneven skin color and skin morphology. 3. The method for selecting a cosmetic according to claim 1, wherein the nonuniform skin color is a presence state of melanin and / or color unevenness. 4. The method according to claim 1, wherein the state of the presence of melanin is represented by the amount of melanin present in the keratinocytes and the heterogeneity of the presence in keratinocytes. A method for selecting a cosmetic according to claim 1. 5. The cosmetic according to claim 1, wherein the color unevenness is evaluated by using a color unevenness model created by morphing and comparing with the color unevenness model photograph. Selection method. 6. The method according to claim 1, wherein the evaluation weight as an index is 0.6 to 0.8 for color unevenness with respect to the presence state of melanin of 0.2 to 0.4. A method for selecting a cosmetic according to claim 1. 7. The skin morphology is a wrinkle-forming possibility, which is distinguished by using the texture of the facial skin as an indicator.
7. The method for selecting a cosmetic according to any one of claims 6 to 6. 8. The method for selecting a cosmetic according to claim 7, wherein the disorder of the texture is discriminated by the presence or absence of the directionality. 9. The method for selecting a cosmetic according to claim 7, wherein the skin on the face is the skin between the outer corner of the eyes and the cheek. 10. The cosmetic according to any one of claims 7 to 9, wherein a replica specimen is used. 11. The cosmetic according to claim 1, wherein the color non-uniformity index is compared with the skin morphology index, and a cosmetic is selected so as to correct an index deviating more from the beautiful skin value. A method for selecting a cosmetic according to claim 1. 12. The method for selecting a cosmetic according to claim 1, wherein the sensitivity of the skin is classified into three types according to the degree. 13. The method for selecting a cosmetic according to claim 1, wherein the three skin sensitivity classifications are sensitive skin, slightly sensitive skin and normal skin. 14. The method according to claim 1, wherein the sensitivity of the skin is determined by the shape of the keratinocytes.
15. The method for selecting a cosmetic according to any one of 14 to 14. 15. The selection of the cosmetic according to any one of claims 1 to 14, wherein the keratinocytes for distinguishing skin sensitivity are collected by an adhesive disc transfer method. Law. 16. The cosmetic according to claim 1, wherein the selected cosmetic is a basic cosmetic.