JP2000143509A5 - - Google Patents

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JP2000143509A5
JP2000143509A5 JP1999243278A JP24327899A JP2000143509A5 JP 2000143509 A5 JP2000143509 A5 JP 2000143509A5 JP 1999243278 A JP1999243278 A JP 1999243278A JP 24327899 A JP24327899 A JP 24327899A JP 2000143509 A5 JP2000143509 A5 JP 2000143509A5
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fat
fat emulsion
solution
dispersion medium
average particle
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JP2000143509A (en
JP4717170B2 (en
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平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤および電解質および/またはアミノ酸を含有する溶液を含む栄養輸液製剤。  A nutritional infusion preparation comprising a fat emulsion substantially containing fat particles having an average particle size of 0.003 to 0.100 µm and a dispersion medium and a solution containing an electrolyte and / or an amino acid. 平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤(A)および電解質およびアミノ酸を含有する溶液(B)からなる栄養輸液製剤。  A nutritional infusion preparation comprising a fat emulsion (A) substantially containing fat particles having an average particle size of 0.003 to 0.100 μm and a dispersion medium, and a solution (B) containing an electrolyte and an amino acid. 平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤(A)、電解質を含有する溶液(B−1)およびアミノ酸を含有する溶液(B−2)からなる栄養輸液製剤。  Fat emulsion (A) substantially containing fat particles having an average particle size of 0.003 to 0.100 μm and a dispersion medium, a solution (B-1) containing an electrolyte, and a solution (B-2) containing an amino acid Nutritional infusion formulation consisting of 前記乳化剤および/または少なくとも1つの前記溶液が、糖および/または多価アルコールを含有する請求項1〜3記載の栄養輸液製剤。  The nutritional infusion preparation according to claims 1 to 3, wherein the emulsifier and / or at least one of the solutions contains sugar and / or polyhydric alcohol. 平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤が、さらに電解質および/またはアミノ酸を含有する請求項1〜3記載の栄養輸液製剤。  The nutritional infusion preparation according to claims 1 to 3, wherein the fat emulsion substantially containing fat particles having an average particle diameter of 0.003 to 0.100 µm and a dispersion medium further contains an electrolyte and / or an amino acid. 平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤が、糖および/または多価アルコールの存在下、乳化剤を用いて油脂を乳化させた栄養補給用脂肪乳剤である請求項1〜3記載の栄養輸液製剤。  A fat emulsion containing fat particles having an average particle size of 0.003 to 0.100 μm and a dispersion medium, wherein fats and oils are emulsified using an emulsifier in the presence of sugar and / or polyhydric alcohol, for nutritional supplementation The nutritional infusion preparation according to claims 1 to 3, which is a fat emulsion. 平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤(A)中の油脂の濃度が、0.3〜15.0g/dLである請求項1〜3記載の栄養輸液製剤。  The fat and oil concentration in the fat emulsion (A) substantially containing fat particles having a mean particle size of 0.003 to 0.100 µm and a dispersion medium is 0.3 to 15.0 g / dL. 3. The nutritional infusion preparation according to 3. 前記脂肪乳剤(A)中の糖および/または多価アルコールの濃度が、0〜60g/dLである請求項4記載の栄養輸液製剤。  The nutritional infusion preparation according to claim 4, wherein the concentration of sugar and / or polyhydric alcohol in the fat emulsion (A) is 0 to 60 g / dL. 乳化剤を油脂1重量部に対して、0.1〜0.5重量部配合した請求項6記載の栄養輸液製剤。  The nutritional infusion preparation according to claim 6, wherein 0.1 to 0.5 parts by weight of an emulsifier is added to 1 part by weight of fats and oils. 平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤(A)単独、または該脂肪乳剤(A)および電解質およびアミノ酸を含有する溶液(B)の混合溶液、または該脂肪乳剤(A)、電解質を含有する溶液(B−1)およびアミノ酸を含有する溶液(B−2)の混合溶液の濁度が20〜150度である請求項2〜3記載の栄養輸液製剤。  Fat emulsion (A) alone substantially containing fat particles having an average particle size of 0.003 to 0.100 μm and a dispersion medium, or a mixture of the fat emulsion (A) and a solution (B) containing an electrolyte and an amino acid The turbidity of the solution or a mixed solution of the fat emulsion (A), the electrolyte-containing solution (B-1) and the amino acid-containing solution (B-2) is 20 to 150 degrees. Nutritional infusion formulation. 下記表1に記載される成分により構成される請求項1〜3記載の栄養輸液製剤。
Figure 2000143509
The nutritional infusion preparation according to claims 1 to 3, comprising the components described in Table 1 below.
Figure 2000143509
複数の室を有する容器であって、該室と室との隔離壁が隔離開放可能である輸液容器の一室に、平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤を収納し、他の室に電解質および/またはアミノ酸を含有する溶液を収納したことを特徴とする栄養輸液製剤を収納した輸液容器。  Fat particles having an average particle diameter of 0.003 to 0.100 μm and a dispersion medium are placed in a chamber having a plurality of chambers, and an infusion container in which a separation wall between the chambers can be separated and opened. An infusion container containing a nutritional infusion preparation characterized by containing a fat emulsion substantially contained therein and a solution containing an electrolyte and / or an amino acid in another chamber. 複数の室を有する容器であって、該室と室との隔離壁が隔離開放可能である輸液容器の一室に、平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤(A)を収納し、他の室に電解質およびアミノ酸を含有する溶液(B)を収納したことを特徴とする栄養輸液製剤を収納した輸液容器。  Fat particles having an average particle diameter of 0.003 to 0.100 μm and a dispersion medium are placed in a chamber having a plurality of chambers, and an infusion container in which a separation wall between the chambers can be separated and opened. An infusion container containing a nutritional infusion preparation characterized by containing a fat emulsion (A) substantially contained therein and a solution (B) containing an electrolyte and an amino acid in another chamber. 複数の室を有する容器であって、該室と室との隔離壁が隔離開放可能である輸液容器の一室に、平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤(A)を収納し、他の室に電解質を含有する溶液(B−1)およびアミノ酸を含有する溶液(B−2)をそれぞれ収納したことを特徴とする栄養輸液製剤を収納した輸液容器。  Fat particles having an average particle diameter of 0.003 to 0.100 μm and a dispersion medium are placed in a chamber having a plurality of chambers, and an infusion container in which a separation wall between the chambers can be separated and opened. A nutritional infusion preparation characterized by containing a fat emulsion (A) containing substantially and containing a solution (B-1) containing an electrolyte and a solution (B-2) containing an amino acid in another chamber, respectively. An infusion container containing 油脂を粗乳化した脂肪乳剤を、高圧噴射ホモジナイザーを用い、圧力、2000〜3200kgf/cm2の下、パス回数5〜30パスで精乳化処理し、平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤を調製することを特徴とする脂肪乳剤の製造法。A fat emulsion obtained by roughly emulsifying fats and oils is finely emulsified with a high-pressure jet homogenizer under a pressure of 2000 to 3200 kgf / cm 2 and 5 to 30 passes, and the average particle size is 0.003 to 0.100 μm. A method for producing a fat emulsion, comprising preparing a fat emulsion substantially containing certain fat particles and a dispersion medium. 平均粒子径が0.003〜0.100μmである脂肪粒子および分散媒を実質的に含む脂肪乳剤。A fat emulsion substantially comprising fat particles having an average particle diameter of 0.003 to 0.100 μm and a dispersion medium.
JP24327899A 1998-08-31 1999-08-30 Nutritional infusion preparation Expired - Fee Related JP4717170B2 (en)

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JP24327899A JP4717170B2 (en) 1998-08-31 1999-08-30 Nutritional infusion preparation

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JP10-246108 1998-08-31
JP24610898 1998-08-31
JP1998246108 1998-08-31
JP24327899A JP4717170B2 (en) 1998-08-31 1999-08-30 Nutritional infusion preparation

Related Child Applications (1)

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JP2007179302A Division JP2007262088A (en) 1998-08-31 2007-07-09 Nutrition transfusion formulation

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JP2000143509A JP2000143509A (en) 2000-05-23
JP2000143509A5 true JP2000143509A5 (en) 2005-09-29
JP4717170B2 JP4717170B2 (en) 2011-07-06

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007262088A (en) * 1998-08-31 2007-10-11 Nipro Corp Nutrition transfusion formulation
JP2010270161A (en) * 2003-08-26 2010-12-02 Otsuka Pharmaceut Factory Inc Side effect-preventing agent in infusion composition
JP4651309B2 (en) * 2003-08-26 2011-03-16 株式会社大塚製薬工場 Side effect inhibitor for infusion compositions
JP5008864B2 (en) * 2005-12-06 2012-08-22 藤森工業株式会社 Chemical container
ES2634142T3 (en) * 2005-12-23 2017-09-26 Ajay Gupta Parenteral nutrition composition containing iron
CN103237541A (en) * 2010-11-29 2013-08-07 株式会社大塚制药工场 Transfusion preparation

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