JP2000120549A - Chemical transferring device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To pump out chemical smoothly, and use a pump hose in low costs as a disposable goods by forming a part separated in an axial direction of a pump hose as an axial pump moved in an axial direction, and providing a bellows part and the pump hose having throttle parts on both sides of the bellows part. SOLUTION: A part of a transfer hose 10 is formed as a pump hose 16, and is inserted into a hose pump 17. In the pump hose 16, a large diameter and a small diameter are arranged, and a bellows part 18 is formed. Controlled close elements V1, V2 are arranged on both sides of the bellows part 18, and formed as a valve capable of shutting off the pump hose 16 by throttling the pump hose 16 or a throttle element. When a movable holder 20 is moved separating from a fixing holder 19, the close element V1 is closed, and the close element V2 is opened. Accordingly, liquid flows from an inlet part 10a of the transfer hose 10 into the pump hose 16. After that, the close element V2 is closed, and the close element V1 is opened.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a chemical transfer device having a transfer hose and a hose pump for transferring a chemical.

[0002]

2. Description of the Related Art In the field of medicine, a drug solution transfer device having a hose pump or a diaphragm pump is used. In hose pumps designed as peristaltic roller pumps or finger pumps, the chemical in the pump hose is pumped by the hose being continuously squeezed in the radial direction. It is an advantage that the medicine to be pumped only contacts the pump hose and not the other functional parts of the pump. Therefore, the risk of contamination is low. However, it is inconvenient that the delivery accuracy of such pumps depends greatly on the dimensional accuracy and operating behavior of the pump hose and varies over time. As a result, the delivery accuracy of such a hose pump is relatively low. Furthermore, hose pumps of this type are generally not self-priming.

[0003] In hose pumps, the pump hose is typically a disposable item that is discarded after a single use. The pump hose must not only be installed on the pump, but must also be connected to the connecting hose, which is disadvantageous in terms of the time required and the danger of mistakes. The bending movement stresses the hose material so that a special pump hose made of, for example, silicone must be used for the pump in order to obtain a long life. Such special hose elements are expensive and require additional mounting effort. Another disadvantage of this known hose pump is the high energy loss due to the bending movement.

[0004] From US Pat. No. 5,718,687 an axial working hose pump is known which comprises a highly elastic pump hose which repeats axial expansion and contraction. This pump hose is provided with integral check valves at its inlet and outlet. Such pump hoses are expensive due to their non-return valves and hose fittings and are quite unsuitable for use as disposable items.

[0005]

SUMMARY OF THE INVENTION It is an object of the present invention to provide a chemical liquid transfer device having an inexpensive pump hose which acts on a medicine to be pumped out and can be used as a disposable product.

[0006]

In the chemical solution transfer device of the present invention, the hose pump is an axial pump in which two axially separated portions of the pump hose are axially moved from each other. As a result, the medicine to be pumped is moved in the longitudinal direction of the pump hose, but is not squeezed. Since the volume of the hose is proportional to the stroke of the pump, the hose pump is operated with a high volumetric accuracy equal to that of a syringe pump. Prior to each pump stroke, periodic stretching and pushing of the hose accurately returns the hose to its initial position. Therefore, it is ensured that each pump stroke starts under the same condition and that the drift of the restoring force does not occur. By pushing and pulling the hose only in the axial direction, even little energy is not converted to bending work. Most of the kinetic energy is used to transport drugs.
Thus, the efficiency of the hose pump is high, so the hose pump is particularly suitable for battery-operated devices. Since the pump hose does not include a valve, the pump hose can be economically manufactured as a disposable product. The valve function is achieved by a controlled closure element that is part of the hose pump rather than the pump hose. This closing element is controlled in synchronization with the pump action.

[0007] Another advantage is that the hose pump is self-priming. This means that the forced control of the pump volume allows the pump to pump liquid from a low level to a high level without the need for a stagnant liquid column. Thus, a hose pump can be used to pump liquid from a liquid container standing on the floor and inject it into the patient.

In a preferred embodiment of the invention, the pump hose is an integral part of the transfer hose and the transfer hose extends from the liquid container, syringe coupling or transfer device to the patient side hose coupling. There are no special requirements regarding the mechanical strength of the pump hose,
The pump hose can be realized as an integral part of the entire transfer hose. This means that a transfer hose having a length of 1 to 2 m has a portion along its length which is deformed to form a pump hose. This deformation can be a bellows or a throttle. At this point, the wall thickness of the pump hose is reduced by annular expansion to achieve the required deformation behavior. Thus, a single hose of disposable goods can be used as the transfer hose, eliminating the assembly effort required to connect the hose coupling and especially the hose section. Because the requirements for the pump hose are low, the entire transfer hose
It may be made of a relatively simple and inexpensive material, for example PVC. The integral part of the transfer hose may also be made of a different material than the rest of the transfer hose, for example a part that is rigidly and permanently connected to the rest of the transfer hose by gluing.

It is preferable to provide a common drive means for the axial movement of the pump hose and the closing element. This driving means may be an electric motor. When the axial drive for the pump movement is a crank drive, the pump movement is a sinusoidal movement. The switching of the closing element takes place at the return point of the axial movement, where the motor does not need to provide any pump energy. Therefore, the energy consumption of the pump movement and the energy consumption of the closing element occur alternately, so that the motor can be designed with relatively low power.

In general, the drug delivery device of the present invention is suitable for any type of infusion or infusion. For example, a medical infusion solution, drug or blood can be pumped. The pump is particularly suitable for blood that is not affected by the pump drive, as the medicament is moved without being squeezed.

The present invention further provides the possibility of forming a bag in the transfer hose and integrating the transfer hose and the bag. Because the hose pump can be selectively transported in both directions, the hose pump can be used to fill the bag by drawing the contents of the supply container into the bag and then transport the liquid from the bag to the patient.

The hose pump is a positive displacement positive displacement pump. The pump can be used to pump the contents of the pump and to transport the contents of the pump to another container or to supply directly to the patient.

[0013] The present invention further relates to a transfer hose for a chemical liquid transfer device, which is provided with an integral pump hose having a bellows portion and a throttle portion on each side thereof. The material thickness is reduced at the constriction.

The transfer hose of the present invention can be manufactured by locally heating a hose having a constant cross section over its entire length, and then deforming the heated portion of the hose. The deformation is performed by the outer mold pressed against the hose wall while applying air pressure to the hose. In this way, the bellows portion and the throttle portion can be manufactured by blow molding.

[0015]

FIG. 1 is a schematic diagram of a liquid transfer device. It comprises a transfer hose 10 made continuously of a homogeneous material and having a substantially constant cross section. The distal end of the transfer hose 10 is provided with a hose coupling 11 consisting of a Luer lock connector. The hose coupling 11 is closed by a closing cap 12 screwed into it. The hose coupling may be connected to a catheter, cannula or other device that reaches the patient's body.

The proximal end of the transfer hose 10 is provided with a drip chamber 13 having a puncture needle 14, which is in this case surrounded by a removable protective cap 15. The puncture needle 15 pierces the bottle's elastomer stopper to drain the contents of the bottle. Hose coupling 11 and puncture needle 1
The transfer hose 10, together with the drip chamber 13 having the 4, forms an integral liquid transfer device designed as a disposable unit which is discarded after use.

A part thereof is formed as a pump hose 16 along the transfer hose 10. The pump hose 16 is
It is inserted into the hose pump 17 and forms a part of this hose pump. Since the pump hose 16 is an integral part of the transfer hose 10, the pump hose 16 is made of the same material as the other parts of the transfer hose. This material is deformed to form the pump hose 16, as described below. The pump hose may be a hose part bonded to the transfer hose 10. The pump hose is a fixed and permanent part of the transfer hose.

The pump hose 16 has a bellows portion 18 in which large diameter portions and small diameter portions are provided alternately to form a concertina structure. On both sides of the bellows section 18, controlled closure elements V1 and V2 engage the pump hose. These closing elements are valves or throttle elements that can squeeze the pump hose and shut off the pump hose at that location. Furthermore, the closing element secures the hose longitudinally. The closing element V1 is provided on a fixed holder 19 that is firmly attached to the hose pump 17. The movable holder 20 is the arrow 2
As shown at 1, the pump hose 16 is moved under control in the longitudinal direction.

When the movable holder 20 is moved away from the fixed holder 19, the closing element V1 is closed while
The closing element V2 is opened. Thus, the liquid flows into the pump hose 16 from the inlet 10a of the transfer hose. At the end of the movement of the movable holder 20, the closing element V2 is closed while the closing element V1 is opened. Next, a pump stroke is performed to move the movable holder 20 to the fixed holder 1.
9 is moved. Here, the pump hose 16
Is transferred into the outlet 10b of the transfer hose 10. At the end of this movement, the closing element V1 is closed again while the closing element V2 is opened. In this way, a precisely defined liquid volume is transported on each pump stroke. The closing elements V1 and V2 are controlled by the common control means 22 in synchronization with the movement of the movable holder 20.

2 to 5, the hose pump 17
Comprises a guide track consisting of two parallel rails 23 and 24. The fixed holder 19 is mounted at a fixed position along the guide track, while the movable holder is moved along the guide track. Movable holder 2
0 is moved longitudinally by the crank drive 25. The crank drive 25 includes the crank disk 2
6 and a connecting rod 27. The connecting rod 27 is eccentrically engaged with the crank disk 26 and is connected to the movable holder 20. When the crank disk 26 rotates, the movable holder 20 is moved linearly first toward the fixed holder 19 and then in the opposite direction. The linear motion of the movable holder 20 is a sinusoidal motion with respect to time. One end of the pump hose 16 is fixed to the fixed holder 19, while the other end of the pump hose 16 is fixed to the movable holder 20. Again, the pump hose 16 is part of the transfer hose 10.
The bellows part 18 is located between the fixed holder 19 and the movable holder 20.

A control shaft 28 extends parallel to the guide rails 23 and 24. The control shaft 28 is designed as a spline shaft having a cross-shaped profile extending in the longitudinal direction and passing through the fixed holder 19 and the movable holder 20. A cam disk 29 which is movable in the longitudinal direction and is a part of the movable holder 20 is mounted on the cross-shaped contour. Corresponding cam disc 29
Are also provided on the fixed holder 19.

The connecting rod driving device 25 is driven by a motor 32 via a gear device 33. The motor 32 is
Further, the control shaft 28 for the closing elements V1 and V2 is driven via the gear device 31.

The control means converts the sinusoidal motion of the movable holder 20 to a motion that provides a substantially constant delivery over time, thereby linearizing the volume / stroke characteristics of the pump device. With parts. This is achieved by driving a motor 32 designed as a stepper motor according to a table in ROM that linearizes the sinusoidal motion.

The pump hose 16 has closing elements V1 and V2.
Has two restricting portions 34 and 35 on which. Aperture part 3
4 and 35 are inserted into the fixed holder 19 and the movable holder 20, and then the fixed holder 19 and the movable holder 20 are closed, so that both ends of the pump hose 16 or both ends of the pump portion forming the pump hose are fixed respectively. It is fixed to the holder 19 or the movable holder 20.

FIGS. 3 and 5 illustrate the control of the closing element V1 by the cam disc 29 driven by the control shaft 28. FIG. The periphery of the cam disk 29 is engaged with a cam follower 36 pressed against the cam disk 29 by a spring 37. The cam follower 36 includes a slide 38 that is movable laterally with respect to the pump hose 16. The peripheral surface of the cam disk 29 has a cam structure for moving the slide 38 between the closed position and the open position.

Assume that the transport direction in FIG. 2 is from left to right. In this case, if the movable holder 20 is close to the fixed holder 19, the closing element V1 is opened while the closing element V2 is closed. The movable holder 20 is displaced rightward, and the pump chamber 40 in the pump hose 16 is moved.
Is dominant as is filled with liquid. When the right limit position of the movable holder 20 is reached, the closing element V1 is closed while the closing element V2 is open.
As the movable holder 20 next approaches the fixed holder 19, the liquid is discharged from the pump chamber 40 in the transport direction.

With each stroke of the pump, a precisely defined volume is transported. Due to the continuous peripheral ribs, the bellows part 18 has a great dimensional stability that is less susceptible to crushing. Thus, the pump can also be used to aspirate.

FIG. 6 shows the pump hose 16 separately. The figure shows a bellows section 18 formed by a sinusoidally extending surrounding wave of the hose wall. Two throttle parts 3
4 and 35 are spaced a short distance from the bellows section 18. At these constrictions, the wall diameter decreases as a result of the increased hose diameter. The wall thickness of the bellows section 18 is also reduced by increasing the hose length. Instead of the illustrated embodiment, the diaphragm may be flattened.

In the embodiment shown in FIG.
6 is also an integral part of the transfer hose 10. The pump hose 16 is formed by plasticizing the material of the transfer hose 10 by local heating. In an outer mold having the intended contour of the pump hose 16 in its inner contour, the hose is expanded or pressurized from the inside so that its outer wall abuts the mold,
At the same time, the above-mentioned reduced wall thickness is obtained. Thereafter, the hose shape thus obtained is solidified by cooling. The hose does not require cutting. The pump part of the transfer hose 10 manufactured in this manner is a hose pump 1
7 and does not require mounting.

In the modification of FIG. 1A, the drip chamber 1 of FIG.
3 has been replaced by a syringe coupling 41 consisting of a luer lock connector coupled to a transfer hose. This syringe coupling 41 serves to connect the device to a syringe filled with the liquid to be pumped. In this manner, by injecting liquid from the syringe using the hose pump 17 and transferring the liquid to the patient, for example, infusion is performed from the syringe as with a conventional syringe pump.

Another variant is shown in FIG. Here, the bag 42 which is rigidly connected to the transfer hose 10 and which is preferably formed integrally with the transfer hose 10 is a liquid container. This bag 42 can contain the liquid to be pumped. However, first the empty bag 42
Can be charged by operating the hose pump 17 in the reverse rotation mode. When the bag 42 is being filled, the bag 42 is emptied in the forward mode.

In the embodiment shown in FIG.
The pump hose 16 having 8 is arranged between the fixed holder 19 and the linearly movable holder 20. To prevent movement of the movable holder 20 from causing movement of the supply hose outside the pump, a second bellows 44 is connected to the inlet of the movable holder 20 and rigidly connected to the fixed holder 45. . An external supply hose is connected to the fixed holder 45. The fixed holder 45 does not include any valves. The second bellows 44 forms a length compensating conduit. A hose loop may be used instead of the bellows. The fixed holder 19 and the movable holder 20 correspond to those of the first embodiment, and each includes a control throttle valve.

[Brief description of the drawings]

FIG. 1 is a schematic view of a transfer hose with an integral pump hose, wherein (a) and (b) show a variation of the proximal end of the transfer hose.

FIG. 2 is a side view of the hose pump.

FIG. 3 is a partial cross-sectional front view of a cam drive unit.

FIG. 4 is a plan view of a hose pump.

FIG. 5 is an enlarged detail view of a portion V in FIG. 3;

FIG. 6 is a longitudinal sectional view of a pump hose.

FIG. 7 shows an embodiment with two fixed holders.

[Explanation of symbols]

 Reference Signs List 10 transfer hose 13 drip chamber 16 pump hose 17 hose pump 18 bellows section 19 fixed holder 20 movable holder 29 cam disk 34 throttle section 35 throttle section 45 fixed holder

 ──────────────────────────────────────────────────続 き Continued on the front page (72) Inventor Hans Görlach 3441 Marsberger Strasse 42, Marsberg, Germany

Claims (8)

[Claims] 1. At least one transfer hose (10);
A hose pump (17);
7) is configured as an axial pump for axially moving the two spaced apart portions of the pump hose (16) with respect to each other, and the hose pump (17) is further configured as an axial pump.
6) A chemical liquid transfer device including a controlled closing element (V1, V2) for alternately narrowing the throttle portions (34, 35). 2. The transfer hose (1) is provided with a pump hose (16).
0) and the transfer hose (10) is connected to a liquid container, syringe coupling or transfer device (13, 1).
2. The device according to claim 1, wherein the device extends from 4) to the distal hose coupling (11). 3. The pump hose (16) has a bellows portion (1).
The drug solution transfer device according to claim 1, further comprising (8). 4. A hose pump (17) comprising a fixed holder (19) and a holder (20) that is periodically movable with respect to the fixed holder (19). A controlled closure element (V1, V) for restricting a restriction (34, 35) of a pump hose (16) by a holder (20).
The drug solution transfer device according to claim 1, further comprising (2). 5. A pump hose (16) and a closing element (V)
The chemical liquid transfer device according to claim 1, further comprising a common drive unit for axial movement of (1, V2). 6. The chemical transfer device according to claim 1, wherein the transfer hose has a bag integrally formed as a liquid container. 7. One end is connected to the movable holder (20) of the hose pump (17) and the other end is fixed to the fixed holder (45).
2. A device according to claim 1, further comprising a compensating conduit (44) connected to the device. 8. The transfer hose of the chemical solution transfer device according to claim 1, further comprising an integral pump hose (16), wherein the integral hose pump (16) has a bellows section (18) and a throttle section (2) on both sides. 3
4, 35).