JP2000102616A - Medical nitrogen monoxide inhalation device - Google Patents
Medical nitrogen monoxide inhalation deviceInfo
- Publication number
- JP2000102616A JP2000102616A JP10312675A JP31267598A JP2000102616A JP 2000102616 A JP2000102616 A JP 2000102616A JP 10312675 A JP10312675 A JP 10312675A JP 31267598 A JP31267598 A JP 31267598A JP 2000102616 A JP2000102616 A JP 2000102616A
- Authority
- JP
- Japan
- Prior art keywords
- nitrogen monoxide
- air
- medical
- inhalation device
- nitric oxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Respiratory Apparatuses And Protective Means (AREA)
Abstract
Description
【0001】[0001]
【産業上の利用分野】この発明は、一酸化窒素を空気或
いは乾燥空気から放電を用いて生成し、人工呼吸器に組
みこむことにより、重症呼吸不全患者等の治療に用い
る。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is used for treating patients with severe respiratory failure by producing nitric oxide from air or dry air by means of electric discharge and incorporating it into a ventilator.
【0002】[0002]
【従来の技術】窒素希釈の一酸化窒素ボンベを人工呼吸
器に組みこんで、重症呼吸不全患者等の治療に用いられ
ている。2. Description of the Related Art Nitrogen monoxide cylinders diluted with nitrogen are incorporated in a ventilator and used for treating patients with severe respiratory failure.
【0003】[0003]
【発明が解決しようとする課題】従来使われている窒素
希釈一酸化窒素ボンベは、取り扱いが難しく、ボンベ用
レギュレータの取り扱いのミスや一酸化窒素のリークが
おこると、医療現場での重大事故となる可能性がある。
窒素希釈一酸化窒素ボンベを使わない安全な一酸化窒素
生成装置開発が課題である。Conventionally, a nitrogen-diluted nitric oxide cylinder is difficult to handle. If a cylinder regulator is mishandled or nitric oxide leaks, a serious accident at a medical site may occur. Could be.
The challenge is to develop a safe nitric oxide generator that does not use nitrogen-diluted nitric oxide cylinders.
【0004】[0004]
【課題を解決する手段】空気或いは乾燥空気を放電領域
に流し、放電反応により一酸化窒素を生成する。同時に
できた二酸化窒素は加熱されたモリブデンとの反応によ
り取り除く。この一酸化窒素生成装置を人工呼吸器に組
み込んで患者の治療に用いる。[0007] Air or dry air is caused to flow in a discharge area to generate nitric oxide by a discharge reaction. Simultaneous nitrogen dioxide is removed by reaction with the heated molybdenum. The nitric oxide generator is incorporated into a ventilator and used for treating patients.
【0005】[0005]
【作用】空気或いは乾燥空気を放電領域に流すと、酸素
と窒素の電離、解離、加熱等の放電反応により一酸化窒
素が生成される。同時に少量の有毒な二酸化窒素が生成
されるが、加熱されたモリブデン中に放電領域を通った
気体を流すと、二酸化窒素は一酸化窒素に変わる。これ
を従来の人工呼吸器に組み込むことにより、必要なだけ
の一酸化窒素を生成して患者に吸入させることが可能と
なり、医療現場での重大事故となる可能性がある一酸化
窒素の入った高圧ボンベを使う必要がなくなる。When air or dry air flows through the discharge region, nitric oxide is generated by a discharge reaction such as ionization, dissociation, and heating of oxygen and nitrogen. At the same time, a small amount of toxic nitrogen dioxide is produced, but when gas is passed through the discharge zone into the heated molybdenum, the nitrogen dioxide is converted to nitric oxide. By incorporating this into a conventional ventilator, it is possible to generate as much nitric oxide as needed and inhale it to the patient, which contains nitric oxide, which can be a serious accident at the medical site. Eliminates the need for high pressure cylinders.
【0006】[0006]
【実施例】図1は、本発明の1実施例である。高電圧電
源1でコンデンサ2を充電し、スイッチ3を閉じること
により、対向した電極4に高電圧を印加し、パルスアー
ク放電を起こす。空気又は乾燥空気5を放電中に流し、
一酸化窒素を生成する。抵抗6はコンデンサ2充電中、
電極4の電圧を小さくするためにある。コンデンサは2
0nF、充電電圧は22kVとした。パルスアーク放電
は一秒間に数回の割合で起こした。このとき生成された
一酸化窒素濃度は500ppmであったコンデンサ容
量、充電電圧、繰り返し周波数、流量等を変化し、一酸
化窒素濃度を調整する。加熱されたモリブデン7を通す
ことにより、生成された二酸化窒素は除去できた。人工
呼吸器8に組み込むことにより、医療用一酸化窒素吸入
装置となる。図にはテスト用肺9も示している。FIG. 1 shows an embodiment of the present invention. When the capacitor 2 is charged by the high-voltage power supply 1 and the switch 3 is closed, a high voltage is applied to the opposing electrode 4 to cause a pulse arc discharge. Flowing air or dry air 5 during discharge,
Produces nitric oxide. While the resistor 6 is charging the capacitor 2,
This is for reducing the voltage of the electrode 4. Capacitor is 2
0 nF and the charging voltage were 22 kV. Pulse arc discharge occurred several times a second. The concentration of nitric oxide generated at this time is adjusted to 500 ppm by changing the capacitor capacity, charging voltage, repetition frequency, flow rate, and the like. By passing the heated molybdenum 7, the generated nitrogen dioxide could be removed. By incorporating it into the respirator 8, a medical nitric oxide inhaler is obtained. The figure also shows a test lung 9.
【0007】[0007]
【発明の効果】本発明により、必要な時に必要な量だけ
空気から一酸化窒素が生成できるため、一酸化窒素の貯
蔵が必要でなくなり、NOボンベを用いない医療用一酸
化窒素吸入装置が開発できる。高圧ボンベからの一酸化
窒素が空気中に漏れて有毒の二酸化窒素となり、医療現
場での重大事故が起こるのを防ぐことが可能となった。According to the present invention, since nitric oxide can be generated from air in a required amount when required, a storage of nitric oxide is not required, and a medical nitric oxide inhaler which does not use a NO cylinder has been developed. it can. Nitric oxide from the high-pressure cylinder leaked into the air and turned into toxic nitrogen dioxide, which made it possible to prevent serious accidents at medical sites.
【図1】 本発明の一実施例である。FIG. 1 is an embodiment of the present invention.
1 高電圧電源 2 コンデンサ 3 ス
イッチ 4 電極 5 空気 6 抵
抗 7 モリブデン 8 人工呼吸器 9 テ
スト用肺DESCRIPTION OF SYMBOLS 1 High voltage power supply 2 Capacitor 3 Switch 4 Electrode 5 Air 6 Resistance 7 Molybdenum 8 Ventilator 9 Test lung
Claims (3)
療用一酸化窒素を生成する方法。1. A method for producing medical nitric oxide using discharge from air or dry air.
酸化窒素を除去する方法。2. A method for removing harmful nitrogen dioxide using heated molybdenum.
吸器。3. A respirator incorporating a nitric oxide generator.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10312675A JP2000102616A (en) | 1998-09-28 | 1998-09-28 | Medical nitrogen monoxide inhalation device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10312675A JP2000102616A (en) | 1998-09-28 | 1998-09-28 | Medical nitrogen monoxide inhalation device |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2000102616A true JP2000102616A (en) | 2000-04-11 |
Family
ID=18032079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10312675A Pending JP2000102616A (en) | 1998-09-28 | 1998-09-28 | Medical nitrogen monoxide inhalation device |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2000102616A (en) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006273677A (en) * | 2005-03-30 | 2006-10-12 | Kumamoto Univ | Nitrogen monoxide (no) generating device |
JP2016512743A (en) * | 2013-03-15 | 2016-05-09 | ザ ジェネラル ホスピタル コーポレイション | Inhalation synthesis of nitric oxide |
JP2016516488A (en) * | 2013-03-15 | 2016-06-09 | ザ ジェネラル ホスピタル コーポレイション | Synthesis of nitric oxide for inhalation |
CN105726292A (en) * | 2014-08-26 | 2016-07-06 | 皇甫起万 | Device for generating steam containing nitric oxide |
US10239038B2 (en) | 2017-03-31 | 2019-03-26 | The General Hospital Corporation | Systems and methods for a cooled nitric oxide generator |
US10286176B2 (en) | 2017-02-27 | 2019-05-14 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US10328228B2 (en) | 2017-02-27 | 2019-06-25 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
US11045620B2 (en) | 2019-05-15 | 2021-06-29 | Third Pole, Inc. | Electrodes for nitric oxide generation |
US11479464B2 (en) | 2019-05-15 | 2022-10-25 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US11497878B2 (en) | 2014-10-20 | 2022-11-15 | The General Hospital Corporation | Systems and methods for synthesis of nitric oxide |
US11617850B2 (en) | 2016-03-25 | 2023-04-04 | The General Hospital Corporation | Delivery systems and methods for electric plasma synthesis of nitric oxide |
US11691879B2 (en) | 2020-01-11 | 2023-07-04 | Third Pole, Inc. | Systems and methods for nitric oxide generation with humidity control |
US11827989B2 (en) | 2020-06-18 | 2023-11-28 | Third Pole, Inc. | Systems and methods for preventing and treating infections with nitric oxide |
US11833309B2 (en) | 2017-02-27 | 2023-12-05 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US11975139B2 (en) | 2021-09-23 | 2024-05-07 | Third Pole, Inc. | Systems and methods for delivering nitric oxide |
-
1998
- 1998-09-28 JP JP10312675A patent/JP2000102616A/en active Pending
Cited By (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006273677A (en) * | 2005-03-30 | 2006-10-12 | Kumamoto Univ | Nitrogen monoxide (no) generating device |
JP2021007861A (en) * | 2013-03-15 | 2021-01-28 | ザ ジェネラル ホスピタル コーポレイション | Synthesis of nitric oxide for inhalation |
US10293133B2 (en) | 2013-03-15 | 2019-05-21 | The General Hospital Corporation | Inspiratory synthesis of nitric oxide |
US12011544B2 (en) | 2013-03-15 | 2024-06-18 | The General Hospital Corporation | Inspiratory synthesis of nitric oxide |
JP2016516488A (en) * | 2013-03-15 | 2016-06-09 | ザ ジェネラル ホスピタル コーポレイション | Synthesis of nitric oxide for inhalation |
JP2018140202A (en) * | 2013-03-15 | 2018-09-13 | ザ ジェネラル ホスピタル コーポレイション | Synthesis of nitric oxide gas for inhalation |
US10279139B2 (en) | 2013-03-15 | 2019-05-07 | The General Hospital Corporation | Synthesis of nitric oxide gas for inhalation |
JP2016512743A (en) * | 2013-03-15 | 2016-05-09 | ザ ジェネラル ホスピタル コーポレイション | Inhalation synthesis of nitric oxide |
US10773047B2 (en) | 2013-03-15 | 2020-09-15 | The General Hospital Corporation | Synthesis of nitric oxide gas for inhalation |
US10646682B2 (en) | 2013-03-15 | 2020-05-12 | The General Hospital Corporation | Inspiratory synthesis of nitric oxide |
US10434276B2 (en) | 2013-03-15 | 2019-10-08 | The General Hospital Corporation | Inspiratory synthesis of nitric oxide |
CN105726292A (en) * | 2014-08-26 | 2016-07-06 | 皇甫起万 | Device for generating steam containing nitric oxide |
US11497878B2 (en) | 2014-10-20 | 2022-11-15 | The General Hospital Corporation | Systems and methods for synthesis of nitric oxide |
US11617850B2 (en) | 2016-03-25 | 2023-04-04 | The General Hospital Corporation | Delivery systems and methods for electric plasma synthesis of nitric oxide |
US11911566B2 (en) | 2017-02-27 | 2024-02-27 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
US10576239B2 (en) | 2017-02-27 | 2020-03-03 | Third Pole, Inc. | System and methods for ambulatory generation of nitric oxide |
US10286176B2 (en) | 2017-02-27 | 2019-05-14 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US11376390B2 (en) | 2017-02-27 | 2022-07-05 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US10946163B2 (en) | 2017-02-27 | 2021-03-16 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US10695523B2 (en) | 2017-02-27 | 2020-06-30 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US11033705B2 (en) | 2017-02-27 | 2021-06-15 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
US10532176B2 (en) | 2017-02-27 | 2020-01-14 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US10328228B2 (en) | 2017-02-27 | 2019-06-25 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
US11833309B2 (en) | 2017-02-27 | 2023-12-05 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US11554240B2 (en) | 2017-02-27 | 2023-01-17 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
US11524134B2 (en) | 2017-02-27 | 2022-12-13 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
US11007503B2 (en) | 2017-03-31 | 2021-05-18 | The General Hospital Corporation | Systems and methods for a cooled nitric oxide generator |
US10239038B2 (en) | 2017-03-31 | 2019-03-26 | The General Hospital Corporation | Systems and methods for a cooled nitric oxide generator |
US11478601B2 (en) | 2019-05-15 | 2022-10-25 | Third Pole, Inc. | Electrodes for nitric oxide generation |
US11479464B2 (en) | 2019-05-15 | 2022-10-25 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US11045620B2 (en) | 2019-05-15 | 2021-06-29 | Third Pole, Inc. | Electrodes for nitric oxide generation |
US11691879B2 (en) | 2020-01-11 | 2023-07-04 | Third Pole, Inc. | Systems and methods for nitric oxide generation with humidity control |
US11827989B2 (en) | 2020-06-18 | 2023-11-28 | Third Pole, Inc. | Systems and methods for preventing and treating infections with nitric oxide |
US11975139B2 (en) | 2021-09-23 | 2024-05-07 | Third Pole, Inc. | Systems and methods for delivering nitric oxide |
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