JP2000102616A - Medical nitrogen monoxide inhalation device - Google Patents

Medical nitrogen monoxide inhalation device

Info

Publication number
JP2000102616A
JP2000102616A JP10312675A JP31267598A JP2000102616A JP 2000102616 A JP2000102616 A JP 2000102616A JP 10312675 A JP10312675 A JP 10312675A JP 31267598 A JP31267598 A JP 31267598A JP 2000102616 A JP2000102616 A JP 2000102616A
Authority
JP
Japan
Prior art keywords
nitrogen monoxide
air
medical
inhalation device
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10312675A
Other languages
Japanese (ja)
Inventor
Shusuke Akiyama
秀典 秋山
Kazufumi Okamoto
和文 岡元
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP10312675A priority Critical patent/JP2000102616A/en
Publication of JP2000102616A publication Critical patent/JP2000102616A/en
Pending legal-status Critical Current

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  • Respiratory Apparatuses And Protective Means (AREA)

Abstract

PROBLEM TO BE SOLVED: To provide a medical nitrogen monoxide inhalation device incorporated to a respirator for generating only a necessary quantity of nitrogen monoxide from air or dried air at a necessary time, thus avoiding the use of a nitrogen monoxide cylinder which probably causes serious accidents on a site of medical care. SOLUTION: A capacitor 2 is charged with a high-voltage power supply 1 and a switch 3 is closed to apply a high voltage between opposite bar electrodes 4 and repeat pulse arc discharge. Air or dried air 5 is allowed to flow in the discharge to generate nitrogen monoxide. A resistor 6 is disposed for reducing the voltage of the electrodes 4 during the charging of the capacitor 2. Generated nitrogen dioxide is removed by a gas passing through heated molybdenum 7. This structure serves as a medical nitrogen monoxide inhalation device when it is incorporated to a respirator 8. 9 in the figure represents a lung for tests.

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【0001】[0001]

【産業上の利用分野】この発明は、一酸化窒素を空気或
いは乾燥空気から放電を用いて生成し、人工呼吸器に組
みこむことにより、重症呼吸不全患者等の治療に用い
る。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is used for treating patients with severe respiratory failure by producing nitric oxide from air or dry air by means of electric discharge and incorporating it into a ventilator.

【0002】[0002]

【従来の技術】窒素希釈の一酸化窒素ボンベを人工呼吸
器に組みこんで、重症呼吸不全患者等の治療に用いられ
ている。
2. Description of the Related Art Nitrogen monoxide cylinders diluted with nitrogen are incorporated in a ventilator and used for treating patients with severe respiratory failure.

【0003】[0003]

【発明が解決しようとする課題】従来使われている窒素
希釈一酸化窒素ボンベは、取り扱いが難しく、ボンベ用
レギュレータの取り扱いのミスや一酸化窒素のリークが
おこると、医療現場での重大事故となる可能性がある。
窒素希釈一酸化窒素ボンベを使わない安全な一酸化窒素
生成装置開発が課題である。
Conventionally, a nitrogen-diluted nitric oxide cylinder is difficult to handle. If a cylinder regulator is mishandled or nitric oxide leaks, a serious accident at a medical site may occur. Could be.
The challenge is to develop a safe nitric oxide generator that does not use nitrogen-diluted nitric oxide cylinders.

【0004】[0004]

【課題を解決する手段】空気或いは乾燥空気を放電領域
に流し、放電反応により一酸化窒素を生成する。同時に
できた二酸化窒素は加熱されたモリブデンとの反応によ
り取り除く。この一酸化窒素生成装置を人工呼吸器に組
み込んで患者の治療に用いる。
[0007] Air or dry air is caused to flow in a discharge area to generate nitric oxide by a discharge reaction. Simultaneous nitrogen dioxide is removed by reaction with the heated molybdenum. The nitric oxide generator is incorporated into a ventilator and used for treating patients.

【0005】[0005]

【作用】空気或いは乾燥空気を放電領域に流すと、酸素
と窒素の電離、解離、加熱等の放電反応により一酸化窒
素が生成される。同時に少量の有毒な二酸化窒素が生成
されるが、加熱されたモリブデン中に放電領域を通った
気体を流すと、二酸化窒素は一酸化窒素に変わる。これ
を従来の人工呼吸器に組み込むことにより、必要なだけ
の一酸化窒素を生成して患者に吸入させることが可能と
なり、医療現場での重大事故となる可能性がある一酸化
窒素の入った高圧ボンベを使う必要がなくなる。
When air or dry air flows through the discharge region, nitric oxide is generated by a discharge reaction such as ionization, dissociation, and heating of oxygen and nitrogen. At the same time, a small amount of toxic nitrogen dioxide is produced, but when gas is passed through the discharge zone into the heated molybdenum, the nitrogen dioxide is converted to nitric oxide. By incorporating this into a conventional ventilator, it is possible to generate as much nitric oxide as needed and inhale it to the patient, which contains nitric oxide, which can be a serious accident at the medical site. Eliminates the need for high pressure cylinders.

【0006】[0006]

【実施例】図1は、本発明の1実施例である。高電圧電
源1でコンデンサ2を充電し、スイッチ3を閉じること
により、対向した電極4に高電圧を印加し、パルスアー
ク放電を起こす。空気又は乾燥空気5を放電中に流し、
一酸化窒素を生成する。抵抗6はコンデンサ2充電中、
電極4の電圧を小さくするためにある。コンデンサは2
0nF、充電電圧は22kVとした。パルスアーク放電
は一秒間に数回の割合で起こした。このとき生成された
一酸化窒素濃度は500ppmであったコンデンサ容
量、充電電圧、繰り返し周波数、流量等を変化し、一酸
化窒素濃度を調整する。加熱されたモリブデン7を通す
ことにより、生成された二酸化窒素は除去できた。人工
呼吸器8に組み込むことにより、医療用一酸化窒素吸入
装置となる。図にはテスト用肺9も示している。
FIG. 1 shows an embodiment of the present invention. When the capacitor 2 is charged by the high-voltage power supply 1 and the switch 3 is closed, a high voltage is applied to the opposing electrode 4 to cause a pulse arc discharge. Flowing air or dry air 5 during discharge,
Produces nitric oxide. While the resistor 6 is charging the capacitor 2,
This is for reducing the voltage of the electrode 4. Capacitor is 2
0 nF and the charging voltage were 22 kV. Pulse arc discharge occurred several times a second. The concentration of nitric oxide generated at this time is adjusted to 500 ppm by changing the capacitor capacity, charging voltage, repetition frequency, flow rate, and the like. By passing the heated molybdenum 7, the generated nitrogen dioxide could be removed. By incorporating it into the respirator 8, a medical nitric oxide inhaler is obtained. The figure also shows a test lung 9.

【0007】[0007]

【発明の効果】本発明により、必要な時に必要な量だけ
空気から一酸化窒素が生成できるため、一酸化窒素の貯
蔵が必要でなくなり、NOボンベを用いない医療用一酸
化窒素吸入装置が開発できる。高圧ボンベからの一酸化
窒素が空気中に漏れて有毒の二酸化窒素となり、医療現
場での重大事故が起こるのを防ぐことが可能となった。
According to the present invention, since nitric oxide can be generated from air in a required amount when required, a storage of nitric oxide is not required, and a medical nitric oxide inhaler which does not use a NO cylinder has been developed. it can. Nitric oxide from the high-pressure cylinder leaked into the air and turned into toxic nitrogen dioxide, which made it possible to prevent serious accidents at medical sites.

【図面の簡単な説明】[Brief description of the drawings]

【図1】 本発明の一実施例である。FIG. 1 is an embodiment of the present invention.

【符号の説明】[Explanation of symbols]

1 高電圧電源 2 コンデンサ 3 ス
イッチ 4 電極 5 空気 6 抵
抗 7 モリブデン 8 人工呼吸器 9 テ
スト用肺
DESCRIPTION OF SYMBOLS 1 High voltage power supply 2 Capacitor 3 Switch 4 Electrode 5 Air 6 Resistance 7 Molybdenum 8 Ventilator 9 Test lung

Claims (3)

【特許請求の範囲】[Claims] 【請求項1】 空気或いは乾燥空気から放電を用いて医
療用一酸化窒素を生成する方法。
1. A method for producing medical nitric oxide using discharge from air or dry air.
【請求項2】 加熱されたモリブデンを用いて有害な二
酸化窒素を除去する方法。
2. A method for removing harmful nitrogen dioxide using heated molybdenum.
【請求項3】 一酸化窒素生成装置を組み込んだ人工呼
吸器。
3. A respirator incorporating a nitric oxide generator.
JP10312675A 1998-09-28 1998-09-28 Medical nitrogen monoxide inhalation device Pending JP2000102616A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10312675A JP2000102616A (en) 1998-09-28 1998-09-28 Medical nitrogen monoxide inhalation device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10312675A JP2000102616A (en) 1998-09-28 1998-09-28 Medical nitrogen monoxide inhalation device

Publications (1)

Publication Number Publication Date
JP2000102616A true JP2000102616A (en) 2000-04-11

Family

ID=18032079

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10312675A Pending JP2000102616A (en) 1998-09-28 1998-09-28 Medical nitrogen monoxide inhalation device

Country Status (1)

Country Link
JP (1) JP2000102616A (en)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006273677A (en) * 2005-03-30 2006-10-12 Kumamoto Univ Nitrogen monoxide (no) generating device
JP2016512743A (en) * 2013-03-15 2016-05-09 ザ ジェネラル ホスピタル コーポレイション Inhalation synthesis of nitric oxide
JP2016516488A (en) * 2013-03-15 2016-06-09 ザ ジェネラル ホスピタル コーポレイション Synthesis of nitric oxide for inhalation
CN105726292A (en) * 2014-08-26 2016-07-06 皇甫起万 Device for generating steam containing nitric oxide
US10239038B2 (en) 2017-03-31 2019-03-26 The General Hospital Corporation Systems and methods for a cooled nitric oxide generator
US10286176B2 (en) 2017-02-27 2019-05-14 Third Pole, Inc. Systems and methods for generating nitric oxide
US10328228B2 (en) 2017-02-27 2019-06-25 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
US11045620B2 (en) 2019-05-15 2021-06-29 Third Pole, Inc. Electrodes for nitric oxide generation
US11479464B2 (en) 2019-05-15 2022-10-25 Third Pole, Inc. Systems and methods for generating nitric oxide
US11497878B2 (en) 2014-10-20 2022-11-15 The General Hospital Corporation Systems and methods for synthesis of nitric oxide
US11617850B2 (en) 2016-03-25 2023-04-04 The General Hospital Corporation Delivery systems and methods for electric plasma synthesis of nitric oxide
US11691879B2 (en) 2020-01-11 2023-07-04 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US11827989B2 (en) 2020-06-18 2023-11-28 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
US11833309B2 (en) 2017-02-27 2023-12-05 Third Pole, Inc. Systems and methods for generating nitric oxide
US11975139B2 (en) 2021-09-23 2024-05-07 Third Pole, Inc. Systems and methods for delivering nitric oxide

Cited By (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006273677A (en) * 2005-03-30 2006-10-12 Kumamoto Univ Nitrogen monoxide (no) generating device
JP2021007861A (en) * 2013-03-15 2021-01-28 ザ ジェネラル ホスピタル コーポレイション Synthesis of nitric oxide for inhalation
US10293133B2 (en) 2013-03-15 2019-05-21 The General Hospital Corporation Inspiratory synthesis of nitric oxide
US12011544B2 (en) 2013-03-15 2024-06-18 The General Hospital Corporation Inspiratory synthesis of nitric oxide
JP2016516488A (en) * 2013-03-15 2016-06-09 ザ ジェネラル ホスピタル コーポレイション Synthesis of nitric oxide for inhalation
JP2018140202A (en) * 2013-03-15 2018-09-13 ザ ジェネラル ホスピタル コーポレイション Synthesis of nitric oxide gas for inhalation
US10279139B2 (en) 2013-03-15 2019-05-07 The General Hospital Corporation Synthesis of nitric oxide gas for inhalation
JP2016512743A (en) * 2013-03-15 2016-05-09 ザ ジェネラル ホスピタル コーポレイション Inhalation synthesis of nitric oxide
US10773047B2 (en) 2013-03-15 2020-09-15 The General Hospital Corporation Synthesis of nitric oxide gas for inhalation
US10646682B2 (en) 2013-03-15 2020-05-12 The General Hospital Corporation Inspiratory synthesis of nitric oxide
US10434276B2 (en) 2013-03-15 2019-10-08 The General Hospital Corporation Inspiratory synthesis of nitric oxide
CN105726292A (en) * 2014-08-26 2016-07-06 皇甫起万 Device for generating steam containing nitric oxide
US11497878B2 (en) 2014-10-20 2022-11-15 The General Hospital Corporation Systems and methods for synthesis of nitric oxide
US11617850B2 (en) 2016-03-25 2023-04-04 The General Hospital Corporation Delivery systems and methods for electric plasma synthesis of nitric oxide
US11911566B2 (en) 2017-02-27 2024-02-27 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
US10576239B2 (en) 2017-02-27 2020-03-03 Third Pole, Inc. System and methods for ambulatory generation of nitric oxide
US10286176B2 (en) 2017-02-27 2019-05-14 Third Pole, Inc. Systems and methods for generating nitric oxide
US11376390B2 (en) 2017-02-27 2022-07-05 Third Pole, Inc. Systems and methods for generating nitric oxide
US10946163B2 (en) 2017-02-27 2021-03-16 Third Pole, Inc. Systems and methods for generating nitric oxide
US10695523B2 (en) 2017-02-27 2020-06-30 Third Pole, Inc. Systems and methods for generating nitric oxide
US11033705B2 (en) 2017-02-27 2021-06-15 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
US10532176B2 (en) 2017-02-27 2020-01-14 Third Pole, Inc. Systems and methods for generating nitric oxide
US10328228B2 (en) 2017-02-27 2019-06-25 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
US11833309B2 (en) 2017-02-27 2023-12-05 Third Pole, Inc. Systems and methods for generating nitric oxide
US11554240B2 (en) 2017-02-27 2023-01-17 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
US11524134B2 (en) 2017-02-27 2022-12-13 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
US11007503B2 (en) 2017-03-31 2021-05-18 The General Hospital Corporation Systems and methods for a cooled nitric oxide generator
US10239038B2 (en) 2017-03-31 2019-03-26 The General Hospital Corporation Systems and methods for a cooled nitric oxide generator
US11478601B2 (en) 2019-05-15 2022-10-25 Third Pole, Inc. Electrodes for nitric oxide generation
US11479464B2 (en) 2019-05-15 2022-10-25 Third Pole, Inc. Systems and methods for generating nitric oxide
US11045620B2 (en) 2019-05-15 2021-06-29 Third Pole, Inc. Electrodes for nitric oxide generation
US11691879B2 (en) 2020-01-11 2023-07-04 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US11827989B2 (en) 2020-06-18 2023-11-28 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
US11975139B2 (en) 2021-09-23 2024-05-07 Third Pole, Inc. Systems and methods for delivering nitric oxide

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