ITUA20164357A1 - Metodo di screening ex-vivo - Google Patents

Metodo di screening ex-vivo

Info

Publication number
ITUA20164357A1
ITUA20164357A1 ITUA2016A004357A ITUA20164357A ITUA20164357A1 IT UA20164357 A1 ITUA20164357 A1 IT UA20164357A1 IT UA2016A004357 A ITUA2016A004357 A IT UA2016A004357A IT UA20164357 A ITUA20164357 A IT UA20164357A IT UA20164357 A1 ITUA20164357 A1 IT UA20164357A1
Authority
IT
Italy
Prior art keywords
screening method
vivo screening
vivo
screening
Prior art date
Application number
ITUA2016A004357A
Other languages
English (en)
Inventor
Massimo Bocchi
Andrea Faenza
Laura Rocchi
Original Assignee
Cellply S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellply S R L filed Critical Cellply S R L
Priority to ITUA2016A004357A priority Critical patent/ITUA20164357A1/it
Priority to EP17748570.3A priority patent/EP3469376B1/en
Priority to CN201780049659.8A priority patent/CN109564238A/zh
Priority to EP17176061.4A priority patent/EP3258240B1/en
Priority to US15/623,149 priority patent/US10569270B2/en
Priority to RU2019100237A priority patent/RU2739327C2/ru
Priority to PCT/IB2017/053530 priority patent/WO2017216739A1/en
Priority to KR1020197000680A priority patent/KR20190023067A/ko
Priority to JP2018566240A priority patent/JP7212523B2/ja
Priority to US16/309,832 priority patent/US20190247848A1/en
Priority to BR112018076095-1A priority patent/BR112018076095A2/pt
Priority to CA3027317A priority patent/CA3027317A1/en
Priority to AU2017283802A priority patent/AU2017283802B2/en
Priority to SG11201811104TA priority patent/SG11201811104TA/en
Publication of ITUA20164357A1 publication Critical patent/ITUA20164357A1/it

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011—Control of the position or alignment of the transfer device
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497—Particle shape

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
ITUA2016A004357A 2016-06-14 2016-06-14 Metodo di screening ex-vivo ITUA20164357A1 (it)

Priority Applications (14)

Application Number Priority Date Filing Date Title
ITUA2016A004357A ITUA20164357A1 (it) 2016-06-14 2016-06-14 Metodo di screening ex-vivo
EP17748570.3A EP3469376B1 (en) 2016-06-14 2017-06-14 Screening method
CN201780049659.8A CN109564238A (zh) 2016-06-14 2017-06-14 筛选工具包和方法
EP17176061.4A EP3258240B1 (en) 2016-06-14 2017-06-14 Screening kit and methods
US15/623,149 US10569270B2 (en) 2016-06-14 2017-06-14 Screening kit and method
RU2019100237A RU2739327C2 (ru) 2016-06-14 2017-06-14 Набор и способ скрининга
PCT/IB2017/053530 WO2017216739A1 (en) 2016-06-14 2017-06-14 Screening kit and method
KR1020197000680A KR20190023067A (ko) 2016-06-14 2017-06-14 스크리닝 키트 및 방법
JP2018566240A JP7212523B2 (ja) 2016-06-14 2017-06-14 スクリーニングキットおよび方法
US16/309,832 US20190247848A1 (en) 2016-06-14 2017-06-14 Screening kit and method
BR112018076095-1A BR112018076095A2 (pt) 2016-06-14 2017-06-14 kit de triagem e método
CA3027317A CA3027317A1 (en) 2016-06-14 2017-06-14 Screening kit and method
AU2017283802A AU2017283802B2 (en) 2016-06-14 2017-06-14 Screening kit and method
SG11201811104TA SG11201811104TA (en) 2016-06-14 2017-06-14 Screening kit and method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUA2016A004357A ITUA20164357A1 (it) 2016-06-14 2016-06-14 Metodo di screening ex-vivo

Publications (1)

Publication Number Publication Date
ITUA20164357A1 true ITUA20164357A1 (it) 2017-12-14

Family

ID=57184667

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUA2016A004357A ITUA20164357A1 (it) 2016-06-14 2016-06-14 Metodo di screening ex-vivo

Country Status (1)

Country Link
IT (1) ITUA20164357A1 (it)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012072822A1 (en) * 2010-12-03 2012-06-07 Mindseeds Laboratories Srl Microanalysis of cellular function
US20160161392A1 (en) * 2006-03-31 2016-06-09 Fluxion Biosciences, Inc. Methods and apparatus for the manipulation of particle suspensions and testing thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160161392A1 (en) * 2006-03-31 2016-06-09 Fluxion Biosciences, Inc. Methods and apparatus for the manipulation of particle suspensions and testing thereof
WO2012072822A1 (en) * 2010-12-03 2012-06-07 Mindseeds Laboratories Srl Microanalysis of cellular function

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATRICIO GODOY ET AL: "Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME", ARCHIVES OF TOXICOLOGY, vol. 87, no. 8, 23 August 2013 (2013-08-23), pages 1315 - 1530, XP055206240, ISSN: 0340-5761, DOI: 10.1007/s00204-013-1078-5 *

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