ITTO20020674A0 - Derivati antranilici ad attivita' anticolecistochininica (anti-cck-1), procedimento per la loro preparazione e loro uso farmaceutico - Google Patents

Derivati antranilici ad attivita' anticolecistochininica (anti-cck-1), procedimento per la loro preparazione e loro uso farmaceutico

Info

Publication number
ITTO20020674A0
ITTO20020674A0 IT2002TO000674A ITTO20020674A ITTO20020674A0 IT TO20020674 A0 ITTO20020674 A0 IT TO20020674A0 IT 2002TO000674 A IT2002TO000674 A IT 2002TO000674A IT TO20020674 A ITTO20020674 A IT TO20020674A IT TO20020674 A0 ITTO20020674 A0 IT TO20020674A0
Authority
IT
Italy
Prior art keywords
anticholecystokinin
anthranile
cck
derivatives
activity
Prior art date
Application number
IT2002TO000674A
Other languages
English (en)
Inventor
Francesco Makovec
Antonio Varnavas
Lucia Lassiani
Lucio Claudio Rovati
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Priority to IT2002TO000674A priority Critical patent/ITTO20020674A1/it
Publication of ITTO20020674A0 publication Critical patent/ITTO20020674A0/it
Priority to AT03766505T priority patent/ATE433439T1/de
Priority to EP03766505A priority patent/EP1532105B1/en
Priority to US10/523,075 priority patent/US7294648B2/en
Priority to ES03766505T priority patent/ES2325496T3/es
Priority to PT03766505T priority patent/PT1532105E/pt
Priority to PCT/IB2003/002922 priority patent/WO2004013087A1/en
Priority to CA2493789A priority patent/CA2493789C/en
Priority to DE60327932T priority patent/DE60327932D1/de
Priority to JP2004525597A priority patent/JP4530853B2/ja
Priority to AU2003253114A priority patent/AU2003253114B8/en
Publication of ITTO20020674A1 publication Critical patent/ITTO20020674A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
IT2002TO000674A 2002-07-26 2002-07-26 Derivati antranilici ad attivita' anticolecistochininica (anti-cck-1), procedimento per la loro preparazione e loro uso farmaceutico ITTO20020674A1 (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT2002TO000674A ITTO20020674A1 (it) 2002-07-26 2002-07-26 Derivati antranilici ad attivita' anticolecistochininica (anti-cck-1), procedimento per la loro preparazione e loro uso farmaceutico
AU2003253114A AU2003253114B8 (en) 2002-07-26 2003-07-23 Anthranyl derivatives having an anticholecystokinin activity (anti-cck-1), a process for their preparation, and pharmaceutical use thereof
ES03766505T ES2325496T3 (es) 2002-07-26 2003-07-23 Derivados de antranilo que tienen una actividad anticolecistoquinina (anti-cck-1), un proceso para su preparacion, y uso farmaceutico de ellos.
EP03766505A EP1532105B1 (en) 2002-07-26 2003-07-23 Anthranyl derivatives having an anticholecystokinin activity (anti-cck-1), a process for their preparation, and pharmaceutical use thereof
US10/523,075 US7294648B2 (en) 2002-07-26 2003-07-23 Anthranyl derivatives having an anticholecystokinin activity (anti-cck-1), a process for their preparation, and pharmaceutical use thereof
AT03766505T ATE433439T1 (de) 2002-07-26 2003-07-23 Anthranyl-derivate mit anti-cholecystokinin- aktivität (anti-cck-1) verfahren zu deren herstellung und deren pharmazeutische anwendung
PT03766505T PT1532105E (pt) 2002-07-26 2003-07-23 Derivados de antracilo possuindo uma actividade anticolecistoquinina (anti-cck-1), um processo para a sua preparação e sua utilização farmacêutica
PCT/IB2003/002922 WO2004013087A1 (en) 2002-07-26 2003-07-23 Anthranyl derivatives having an anticholecystokinin activity (anti-cck-1), a process for their preparation, and pharmaceutical use thereof
CA2493789A CA2493789C (en) 2002-07-26 2003-07-23 Anthranyl derivatives having an anti cholecystokinin activity (anti-cck-1), a process for their preparation, and pharmaceutical use thereof
DE60327932T DE60327932D1 (de) 2002-07-26 2003-07-23 Anthranyl-derivate mit anti-cholecystokinin-aktivität (anti-cck-1) verfahren zu deren herstellung und deren pharmazeutische anwendung
JP2004525597A JP4530853B2 (ja) 2002-07-26 2003-07-23 抗コレシストキニン活性(抗−cck−1)を有するアントラニル酸誘導体、その製造法および医薬用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002TO000674A ITTO20020674A1 (it) 2002-07-26 2002-07-26 Derivati antranilici ad attivita' anticolecistochininica (anti-cck-1), procedimento per la loro preparazione e loro uso farmaceutico

Publications (2)

Publication Number Publication Date
ITTO20020674A0 true ITTO20020674A0 (it) 2002-07-26
ITTO20020674A1 ITTO20020674A1 (it) 2004-01-26

Family

ID=11459544

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2002TO000674A ITTO20020674A1 (it) 2002-07-26 2002-07-26 Derivati antranilici ad attivita' anticolecistochininica (anti-cck-1), procedimento per la loro preparazione e loro uso farmaceutico

Country Status (11)

Country Link
US (1) US7294648B2 (it)
EP (1) EP1532105B1 (it)
JP (1) JP4530853B2 (it)
AT (1) ATE433439T1 (it)
AU (1) AU2003253114B8 (it)
CA (1) CA2493789C (it)
DE (1) DE60327932D1 (it)
ES (1) ES2325496T3 (it)
IT (1) ITTO20020674A1 (it)
PT (1) PT1532105E (it)
WO (1) WO2004013087A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ542491A (en) 2003-03-28 2009-04-30 Janssen Pharmaceutica Nv Benzo[1,2,5]thiadiazole compounds as CCK2 modulators
BRPI0413449A (pt) * 2003-08-08 2006-10-17 Janssen Pharmaceutica Nv compostos de quinoxalina
MX2007003623A (es) 2004-09-24 2007-09-11 Johnson & Johnson Compuestos sulfonamida.

Also Published As

Publication number Publication date
CA2493789A1 (en) 2004-02-12
JP4530853B2 (ja) 2010-08-25
EP1532105A1 (en) 2005-05-25
JP2005533866A (ja) 2005-11-10
AU2003253114B2 (en) 2009-07-16
ATE433439T1 (de) 2009-06-15
CA2493789C (en) 2012-05-01
ES2325496T3 (es) 2009-09-07
PT1532105E (pt) 2009-06-29
AU2003253114A1 (en) 2004-02-23
US20060111304A1 (en) 2006-05-25
US7294648B2 (en) 2007-11-13
ITTO20020674A1 (it) 2004-01-26
EP1532105B1 (en) 2009-06-10
WO2004013087A1 (en) 2004-02-12
AU2003253114B8 (en) 2009-08-13
DE60327932D1 (de) 2009-07-23

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