ITMI931082A0 - Coniugati di farmaci antivirali ad attivita' epatotropicaq relativi veicolanti e composizioni farmaceutiche che li contengono - Google Patents

Coniugati di farmaci antivirali ad attivita' epatotropicaq relativi veicolanti e composizioni farmaceutiche che li contengono

Info

Publication number
ITMI931082A0
ITMI931082A0 IT93MI1082A ITMI931082A ITMI931082A0 IT MI931082 A0 ITMI931082 A0 IT MI931082A0 IT 93MI1082 A IT93MI1082 A IT 93MI1082A IT MI931082 A ITMI931082 A IT MI931082A IT MI931082 A0 ITMI931082 A0 IT MI931082A0
Authority
IT
Italy
Prior art keywords
activityq
hepatotropic
conjugates
contain
pharmaceutical compositions
Prior art date
Application number
IT93MI1082A
Other languages
English (en)
Inventor
Luigi Fimme
Corrado Busi
Stefano Giuseppina Di
Alessandro Mattioli
Massimo Baldacci
Original Assignee
Baldacci Lab Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baldacci Lab Spa filed Critical Baldacci Lab Spa
Publication of ITMI931082A0 publication Critical patent/ITMI931082A0/it
Priority to ITMI931082A priority Critical patent/IT1270817B/it
Priority to BR9405378-2A priority patent/BR9405378A/pt
Priority to AU69970/94A priority patent/AU6997094A/en
Priority to JP7500223A priority patent/JPH07509495A/ja
Priority to AT94918793T priority patent/ATE196256T1/de
Priority to UA95018079A priority patent/UA47386C2/uk
Priority to CA002141028A priority patent/CA2141028A1/en
Priority to PT94918793T priority patent/PT652776E/pt
Priority to KR1019950700270A priority patent/KR100295579B1/ko
Priority to PCT/EP1994/001702 priority patent/WO1994027642A1/en
Priority to RU95105590A priority patent/RU2140292C1/ru
Priority to DE69425860T priority patent/DE69425860T2/de
Priority to EP94918793A priority patent/EP0652776B1/en
Priority to ES94918793T priority patent/ES2152320T3/es
Priority to HU9500585A priority patent/HU221306B1/hu
Publication of ITMI931082A1 publication Critical patent/ITMI931082A1/it
Application granted granted Critical
Publication of IT1270817B publication Critical patent/IT1270817B/it
Priority to US09/053,279 priority patent/US5959077A/en
Priority to US09/325,182 priority patent/US6291638B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
ITMI931082A 1993-05-26 1993-05-26 Coniugati di farmaci antivirali ad attivita' epatotropica, relativi veicolanti e composizioni farmaceutiche che li contengono IT1270817B (it)

Priority Applications (17)

Application Number Priority Date Filing Date Title
ITMI931082A IT1270817B (it) 1993-05-26 1993-05-26 Coniugati di farmaci antivirali ad attivita' epatotropica, relativi veicolanti e composizioni farmaceutiche che li contengono
KR1019950700270A KR100295579B1 (ko) 1993-05-26 1994-05-24 항-바이러스성약물,이의담체의간친화성결합물과이를포함하는제약학적조성물
RU95105590A RU2140292C1 (ru) 1993-05-26 1994-05-24 Гепатотропные коньюгаты антивирусных лекарственных средств, их носители, содержащие их фармацевтические композиции, способ получения конъюгатов
JP7500223A JPH07509495A (ja) 1993-05-26 1994-05-24 抗ウイルス剤の肝親和性共役物，その担体，およびそれらを含む薬剤学的組成物
AT94918793T ATE196256T1 (de) 1993-05-26 1994-05-24 Hepatotropische konjugaten von antivirale arzneimittel, traeger und pharmazeutische zusammensetzungen
UA95018079A UA47386C2 (uk) 1993-05-26 1994-05-24 Гепатотропний кон'югат антивірусного лікарського засобу, спосіб його одержання та фармацевтична композиція
CA002141028A CA2141028A1 (en) 1993-05-26 1994-05-24 Hepatotropic conjugates of antiviral drugs, carriers thereof and pharmaceutical compositions containing them
PT94918793T PT652776E (pt) 1993-05-26 1994-05-24 Conjugados hepatropicos de drogas antivirais, seus transportadores e composicoes farmaceuticas que os contem
BR9405378-2A BR9405378A (pt) 1993-05-26 1994-05-24 Conjugados, uso de poliaminoácidos básicos galactolisados como veìculos hepatotrópicos para drogas na forma de conjugados, composição farmacêutica, e, processo para a formação dos conjugados.
PCT/EP1994/001702 WO1994027642A1 (en) 1993-05-26 1994-05-24 Hepatotropic conjugates of antiviral drugs, carriers thereof and pharmaceutical compositions containing them
AU69970/94A AU6997094A (en) 1993-05-26 1994-05-24 Hepatotropic conjugates of antiviral drugs, carriers thereof and pharmaceutical compositions containing them
DE69425860T DE69425860T2 (de) 1993-05-26 1994-05-24 Hepatotropische konjugaten von antivirale arzneimittel, traeger und pharmazeutische zusammensetzungen
EP94918793A EP0652776B1 (en) 1993-05-26 1994-05-24 Hepatotropic conjugates of antiviral drugs, carriers thereof and pharmaceutical compositions containing them
ES94918793T ES2152320T3 (es) 1993-05-26 1994-05-24 Conjugados hepatotropicos de farmacos antivirales, vehiculos para dichos conjugados y composiciones farmaceuticas que los contienen.
HU9500585A HU221306B1 (en) 1993-05-26 1994-05-24 Hepatotropic conjugates of lactosylated basic polyaminoacids containing antiviral drugs, process for preparation thereof and pharmaceutical compositions containing them
US09/053,279 US5959077A (en) 1993-05-26 1998-04-01 Hepatotropic conjugates of antiviral drugs carriers thereof and pharmaceutical compositions containing them
US09/325,182 US6291638B1 (en) 1993-05-26 1999-06-03 Hepatotropic conjugates of antiviral drugs carriers thereof and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI931082A IT1270817B (it) 1993-05-26 1993-05-26 Coniugati di farmaci antivirali ad attivita' epatotropica, relativi veicolanti e composizioni farmaceutiche che li contengono

Publications (3)

Publication Number Publication Date
ITMI931082A0 true ITMI931082A0 (it) 1993-05-26
ITMI931082A1 ITMI931082A1 (it) 1994-11-26
IT1270817B IT1270817B (it) 1997-05-09

Family

ID=11366263

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI931082A IT1270817B (it) 1993-05-26 1993-05-26 Coniugati di farmaci antivirali ad attivita' epatotropica, relativi veicolanti e composizioni farmaceutiche che li contengono

Country Status (15)

Country Link
EP (1) EP0652776B1 (it)
JP (1) JPH07509495A (it)
KR (1) KR100295579B1 (it)
AT (1) ATE196256T1 (it)
AU (1) AU6997094A (it)
BR (1) BR9405378A (it)
CA (1) CA2141028A1 (it)
DE (1) DE69425860T2 (it)
ES (1) ES2152320T3 (it)
HU (1) HU221306B1 (it)
IT (1) IT1270817B (it)
PT (1) PT652776E (it)
RU (1) RU2140292C1 (it)
UA (1) UA47386C2 (it)
WO (1) WO1994027642A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103202804A (zh) * 2013-02-22 2013-07-17 广东先强药业股份有限公司 一种单磷酸阿糖腺苷注射液及其制备方法
WO2018185321A1 (en) * 2017-04-07 2018-10-11 Thomas Crouzier Reinforcement of mucus barrier properties

Also Published As

Publication number Publication date
ATE196256T1 (de) 2000-09-15
KR950702438A (ko) 1995-07-29
CA2141028A1 (en) 1994-12-08
WO1994027642A1 (en) 1994-12-08
JPH07509495A (ja) 1995-10-19
HU221306B1 (en) 2002-09-28
ITMI931082A1 (it) 1994-11-26
KR100295579B1 (ko) 2001-11-22
EP0652776A1 (en) 1995-05-17
EP0652776B1 (en) 2000-09-13
HU9500585D0 (en) 1995-04-28
UA47386C2 (uk) 2002-07-15
BR9405378A (pt) 1999-09-08
PT652776E (pt) 2001-03-30
HUT70481A (en) 1995-10-30
RU95105590A (ru) 1997-02-27
AU6997094A (en) 1994-12-20
DE69425860D1 (de) 2000-10-19
ES2152320T3 (es) 2001-02-01
IT1270817B (it) 1997-05-09
RU2140292C1 (ru) 1999-10-27
DE69425860T2 (de) 2001-04-12

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970529