ITMI20072421A1 - ALLERGENS AND ALLERGOIDS FROM POISON TO BEES - Google Patents

ALLERGENS AND ALLERGOIDS FROM POISON TO BEES

Info

Publication number
ITMI20072421A1
ITMI20072421A1 IT002421A ITMI20072421A ITMI20072421A1 IT MI20072421 A1 ITMI20072421 A1 IT MI20072421A1 IT 002421 A IT002421 A IT 002421A IT MI20072421 A ITMI20072421 A IT MI20072421A IT MI20072421 A1 ITMI20072421 A1 IT MI20072421A1
Authority
IT
Italy
Prior art keywords
allergoids
bees
allergens
poison
Prior art date
Application number
IT002421A
Other languages
Italian (it)
Inventor
Paolo Falagiani
Giovanni Mistrello
Daniela Roncarolo
Dario Zanoni
Original Assignee
Lofarma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lofarma Spa filed Critical Lofarma Spa
Priority to IT002421A priority Critical patent/ITMI20072421A1/en
Priority to CA2708879A priority patent/CA2708879C/en
Priority to PCT/IT2008/000767 priority patent/WO2009081440A2/en
Priority to US12/809,503 priority patent/US8637037B2/en
Priority to EP08865110.4A priority patent/EP2222337B1/en
Priority to ES08865110.4T priority patent/ES2561594T3/en
Priority to RU2010130532/15A priority patent/RU2481122C2/en
Publication of ITMI20072421A1 publication Critical patent/ITMI20072421A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43572—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from bees
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Insects & Arthropods (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT002421A 2007-12-21 2007-12-21 ALLERGENS AND ALLERGOIDS FROM POISON TO BEES ITMI20072421A1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT002421A ITMI20072421A1 (en) 2007-12-21 2007-12-21 ALLERGENS AND ALLERGOIDS FROM POISON TO BEES
CA2708879A CA2708879C (en) 2007-12-21 2008-12-16 Allergens and allergoids from bee venom
PCT/IT2008/000767 WO2009081440A2 (en) 2007-12-21 2008-12-16 Allergens and allergoids from bee venom
US12/809,503 US8637037B2 (en) 2007-12-21 2008-12-16 Allergens and allergoids from bee venom
EP08865110.4A EP2222337B1 (en) 2007-12-21 2008-12-16 Allergens and allergoids from bee venom
ES08865110.4T ES2561594T3 (en) 2007-12-21 2008-12-16 Allergens and allergoids from bee venom
RU2010130532/15A RU2481122C2 (en) 2007-12-21 2008-12-16 Apitoxin allergens and allergoids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002421A ITMI20072421A1 (en) 2007-12-21 2007-12-21 ALLERGENS AND ALLERGOIDS FROM POISON TO BEES

Publications (1)

Publication Number Publication Date
ITMI20072421A1 true ITMI20072421A1 (en) 2009-06-22

Family

ID=40315650

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002421A ITMI20072421A1 (en) 2007-12-21 2007-12-21 ALLERGENS AND ALLERGOIDS FROM POISON TO BEES

Country Status (7)

Country Link
US (1) US8637037B2 (en)
EP (1) EP2222337B1 (en)
CA (1) CA2708879C (en)
ES (1) ES2561594T3 (en)
IT (1) ITMI20072421A1 (en)
RU (1) RU2481122C2 (en)
WO (1) WO2009081440A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0904036A2 (en) * 2009-10-07 2011-06-14 Univ Minas Gerais Production process of bioproducts made from isolated apitoxin components of apis mellifera bees, composition and use
US10232048B1 (en) 2014-11-18 2019-03-19 Divine Api-Logics, LLC Apitherapy method and composition
DE102018113509A1 (en) 2018-06-06 2019-12-12 Philipps-Universität Marburg Microemulsion for dermal hyposensitization with allergens
RU2702120C1 (en) * 2018-08-15 2019-10-04 Общество с ограниченной ответственностью Международный центр традиционной и альтернативной медицины "АПИ" под руководством И.В. Кривопалова - Москвина Treatment of multiple sclerosis according to the method of krivopalov-moskvin
RU2731509C1 (en) * 2019-09-09 2020-09-03 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Method for production of bee venom allergoid for carrying out allergen-specific immunotherapy
KR102634320B1 (en) * 2022-12-08 2024-02-08 주식회사 파나큐라 Composition for diagnosing bee venom allergy comprising phospholipase A2 as an active ingredient

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6780416B1 (en) * 2000-02-18 2004-08-24 Ecole Polytechnique Federale De Lausanne Bee venom polypeptides and methods of use thereof
US7923209B2 (en) 2003-03-14 2011-04-12 Anergis, S.A. Allergen peptide fragments and use thereof
RU2279888C1 (en) * 2004-11-17 2006-07-20 Вера Николаевна Федосеева Bee venum allergoid for allergen-specific therapy of patients with allergic response for bee stinging and method for its preparing
EP1846556B1 (en) * 2004-12-14 2018-04-11 PLS-Design GmbH Cloning of honey bee allergen
US20070003579A1 (en) * 2005-06-30 2007-01-04 Mannkind Corporation Allergen-specific immunotherapy
KR100744755B1 (en) 2006-03-31 2007-08-01 권기록 Method of Isolating Melitin Using Bee Venom

Also Published As

Publication number Publication date
EP2222337B1 (en) 2015-11-11
WO2009081440A3 (en) 2009-09-17
RU2481122C2 (en) 2013-05-10
CA2708879C (en) 2018-07-31
WO2009081440A2 (en) 2009-07-02
US8637037B2 (en) 2014-01-28
US20100297188A1 (en) 2010-11-25
RU2010130532A (en) 2012-01-27
EP2222337A2 (en) 2010-09-01
ES2561594T3 (en) 2016-02-29
CA2708879A1 (en) 2009-07-02

Similar Documents

Publication Publication Date Title
BRPI0821658A2 (en) Antibodies against human nkg2d and uses thereof
BRPI0819909A2 (en) antimesothelin antibodies and their uses
ATE538137T1 (en) ANTIBODIES TO HUMAN IL-22 AND USES THEREOF
BRPI0912198A2 (en) anti-fn14 antibodies and uses thereof
BRPI0811105A2 (en) UNIFIED PROVISION OF PHYSICAL AND VIRTUAL IMAGES
ATE507213T1 (en) HYDROXYMETHYLFURFURALETHER FROM SUGAR OR HMF AND MIXED ALCOHOL
BRPI0913656A2 (en) radioisotope-labeled anti-cdh3 antibodies and uses thereof
EP2174934A4 (en) OXOPYRAZINE DERIVATIVE AND HERBICIDE
DE602007010795D1 (en) LEAVES AND HATCHERS
DK1969846T3 (en) SYSTEMS AND PROCEDURES TO ADMINISTER CONTENT
BRPI0919531A2 (en) antibodies to human il17 and uses thereof
PL2921500T3 (en) Genetically modified human natural killer cell lines
BRPI0814599A2 (en) PESTICIDES AND USES THEREOF
BRPI0906501A2 (en) composition comprising dispersed protein and fat
PT2099321T (en) COMPOSITIONS OF HUMAN MILK AND METHODS OF MANUFACTURE AND USE OF THE SAME
PL2230932T3 (en) Coated pharmaceutical or nutraceutical preparation with increased release of active substance in the large intestine
EP2185112A4 (en) STABILIZED COMPOSITIONS AND THERAPEUTIC FORMULATIONS
EP2475649A4 (en) INDENONIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
ITMI20072421A1 (en) ALLERGENS AND ALLERGOIDS FROM POISON TO BEES
EP2222284A4 (en) EXTENDED RELEASE OF LOCAL ANESTHESICS USING MICROPARTICLES AND SURGICAL APPLICATIONS
EP2020845A4 (en) HARVESTING PROCEDURE AND ARRANGEMENT
DK2274619T3 (en) MILK DISEASES AND APPLICATIONS THEREOF
EP2460455A4 (en) ACTUATOR SYSTEM AND ENDOSCOPIC DEVICE
EP2209392A4 (en) NATURAL PRESERVATIVES AND ANTIMICROBIAL AGENTS
EP2046368A4 (en) ANTI-COCAINE COMPOSITIONS AND TREATMENT