ITMI20030042A1 - Processo di sintesi enzimatica di antibiotici b lattamici. - Google Patents

Processo di sintesi enzimatica di antibiotici b lattamici.

Info

Publication number
ITMI20030042A1
ITMI20030042A1 ITMI20030042A ITMI20030042A1 IT MI20030042 A1 ITMI20030042 A1 IT MI20030042A1 IT MI20030042 A ITMI20030042 A IT MI20030042A IT MI20030042 A1 ITMI20030042 A1 IT MI20030042A1
Authority
IT
Italy
Prior art keywords
synthesis process
enzymatic synthesis
lactamic antibiotics
lactamic
antibiotics
Prior art date
Application number
Other languages
English (en)
Inventor
Lucia Gardossi
Paolo Linda
Micaela Toniutti
Original Assignee
Univ Degli Studi Trieste
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Trieste filed Critical Univ Degli Studi Trieste
Priority to ITMI20030042 priority Critical patent/ITMI20030042A1/it
Priority to PCT/EP2004/000182 priority patent/WO2004062558A2/en
Publication of ITMI20030042A1 publication Critical patent/ITMI20030042A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/04Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/04Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
ITMI20030042 2003-01-14 2003-01-14 Processo di sintesi enzimatica di antibiotici b lattamici. ITMI20030042A1 (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITMI20030042 ITMI20030042A1 (it) 2003-01-14 2003-01-14 Processo di sintesi enzimatica di antibiotici b lattamici.
PCT/EP2004/000182 WO2004062558A2 (en) 2003-01-14 2004-01-14 Process for enzymatic synthesis of βετα-lactam antibiotics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI20030042 ITMI20030042A1 (it) 2003-01-14 2003-01-14 Processo di sintesi enzimatica di antibiotici b lattamici.

Publications (1)

Publication Number Publication Date
ITMI20030042A1 true ITMI20030042A1 (it) 2004-07-15

Family

ID=32697277

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI20030042 ITMI20030042A1 (it) 2003-01-14 2003-01-14 Processo di sintesi enzimatica di antibiotici b lattamici.

Country Status (2)

Country Link
IT (1) ITMI20030042A1 (it)
WO (1) WO2004062558A2 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120316106A1 (en) 2009-12-29 2012-12-13 Yeda Research And Development Co. Ltd. Synergistic antibiotic combinations and derivatives
CN102851332A (zh) * 2012-09-07 2013-01-02 石药集团中诺药业(石家庄)有限公司 一种酶法氨苄西林母液中d(-)苯甘氨酸的回收方法
CN106187795A (zh) * 2016-07-05 2016-12-07 南京红杉生物科技有限公司 一种d‑苯甘氨酸甲酯的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1274658B (it) * 1995-02-28 1997-07-18 Acs Dobfar Spa Procedimento enzimatico migliorato per la produzione di penicilline e cefalosporine
EP0839192B1 (en) * 1995-07-18 2008-12-10 DSM IP Assets B.V. An improved immobilized penicillin g acylase
HU226348B1 (en) * 1996-11-05 2008-09-29 Bristol Myers Squibb Co Mutant penicillin g acylases
AU9254498A (en) * 1997-07-03 1999-01-25 Gist-Brocades B.V. Preparation of enzyme with reduced beta-lactamase activity
DE19823332C2 (de) * 1998-05-26 2000-09-07 Unifar Kimya Sanayii Ve Ticare Verfahren zur enzymatischen Herstellung von Betalactam-Antibiotika

Also Published As

Publication number Publication date
WO2004062558A3 (en) 2005-06-09
WO2004062558A2 (en) 2004-07-29

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