ITFI910160A1 - DIMETHYLAMINE-HYDROXY ACIDS DIPHOSPHONIC AND THEIR SALTS, THEIR PRODUCTION PROCESS AND PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM - Google Patents

DIMETHYLAMINE-HYDROXY ACIDS DIPHOSPHONIC AND THEIR SALTS, THEIR PRODUCTION PROCESS AND PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM

Info

Publication number
ITFI910160A1
ITFI910160A1 IT000160A ITFI910160A ITFI910160A1 IT FI910160 A1 ITFI910160 A1 IT FI910160A1 IT 000160 A IT000160 A IT 000160A IT FI910160 A ITFI910160 A IT FI910160A IT FI910160 A1 ITFI910160 A1 IT FI910160A1
Authority
IT
Italy
Prior art keywords
diphosphonic
dimethylamine
salts
pharmaceutical compositions
production process
Prior art date
Application number
IT000160A
Other languages
Italian (it)
Inventor
Giuseppe Guainai-Ricci
Maurizio Mian
Sergio Rosini
Original Assignee
Gentili Ist Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gentili Ist Spa filed Critical Gentili Ist Spa
Publication of ITFI910160A0 publication Critical patent/ITFI910160A0/en
Priority to ITFI910160A priority Critical patent/IT1247034B/en
Priority to JP5501416A priority patent/JPH06508833A/en
Priority to CA002112250A priority patent/CA2112250A1/en
Priority to EP92913148A priority patent/EP0592488A1/en
Priority to AU21507/92A priority patent/AU2150792A/en
Priority to PCT/IT1992/000058 priority patent/WO1993000348A1/en
Priority to MX9203205A priority patent/MX9203205A/en
Priority to PT100624A priority patent/PT100624B/en
Publication of ITFI910160A1 publication Critical patent/ITFI910160A1/en
Application granted granted Critical
Publication of IT1247034B publication Critical patent/IT1247034B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
ITFI910160A 1991-06-26 1991-06-26 DIMETHYLAMINE-HYDROXY ACIDS DIPHOSPHONICS AND THEIR SALTS, THEIR PRODUCTION PROCESS AND PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM IT1247034B (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ITFI910160A IT1247034B (en) 1991-06-26 1991-06-26 DIMETHYLAMINE-HYDROXY ACIDS DIPHOSPHONICS AND THEIR SALTS, THEIR PRODUCTION PROCESS AND PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM
AU21507/92A AU2150792A (en) 1991-06-26 1992-05-27 Dimethylamino-hydroxy-alkan diphosphonic acids and pharmaceutical compositions containing them
CA002112250A CA2112250A1 (en) 1991-06-26 1992-05-27 Dimethylamino-hydroxy-alkan diphosphonic acids and pharmaceutical compositions containing them
EP92913148A EP0592488A1 (en) 1991-06-26 1992-05-27 Dimethylamino-hydroxy-alkan diphosphonic acids and pharmaceutical compositions containing them
JP5501416A JPH06508833A (en) 1991-06-26 1992-05-27 Dimethylamino-hydroxy-alkanediphosphonic acids and pharmaceutical compositions containing them
PCT/IT1992/000058 WO1993000348A1 (en) 1991-06-26 1992-05-27 Dimethylamino-hydroxy-alkan diphosphonic acids and pharmaceutical compositions containing them
MX9203205A MX9203205A (en) 1991-06-26 1992-06-24 NOVELTY DIMETILAMINO-HIDROXI-ALCAN-DIPHOSPHONIC ACIDS AND SALTS OF THE SAME, IN PRODUCTION PROCEDURE AND RELATED PHARMACEUTICAL COMPOSITIONS.
PT100624A PT100624B (en) 1991-06-26 1992-06-25 NEW DIMETHYLAMINO-HYDROXY-ACANO-DIPHOSPHONIC ACIDS AND ITS SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITFI910160A IT1247034B (en) 1991-06-26 1991-06-26 DIMETHYLAMINE-HYDROXY ACIDS DIPHOSPHONICS AND THEIR SALTS, THEIR PRODUCTION PROCESS AND PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM

Publications (3)

Publication Number Publication Date
ITFI910160A0 ITFI910160A0 (en) 1991-06-26
ITFI910160A1 true ITFI910160A1 (en) 1992-12-26
IT1247034B IT1247034B (en) 1994-12-12

Family

ID=11349724

Family Applications (1)

Application Number Title Priority Date Filing Date
ITFI910160A IT1247034B (en) 1991-06-26 1991-06-26 DIMETHYLAMINE-HYDROXY ACIDS DIPHOSPHONICS AND THEIR SALTS, THEIR PRODUCTION PROCESS AND PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM

Country Status (8)

Country Link
EP (1) EP0592488A1 (en)
JP (1) JPH06508833A (en)
AU (1) AU2150792A (en)
CA (1) CA2112250A1 (en)
IT (1) IT1247034B (en)
MX (1) MX9203205A (en)
PT (1) PT100624B (en)
WO (1) WO1993000348A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303672B1 (en) 1998-07-28 2001-02-23 Nicox Sa NITRATED SALTS OF DRUGS ACTIVE IN BONE DISORDERS
JP4220382B2 (en) * 2001-07-16 2009-02-04 ユニヴェルシテ・パリ・１３ New bisphosphonate derivatives, their preparation and use
DE102014115154A1 (en) * 2014-10-17 2016-04-21 SCV-SpezialChemikalien-Vertrieb GmbH Conjugated bisphosphonates for the diagnosis and treatment of bone diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194748B (en) * 1981-02-12 1988-09-28 Gentili Ist Spa PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF OSTEOPATHIES
IT1201087B (en) * 1982-04-15 1989-01-27 Gentili Ist Spa PHARMACOLOGICALLY ACTIVE BIPPHOSPHONES, PROCEDURE FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
DE3434667A1 (en) * 1984-09-21 1986-04-03 Henkel KGaA, 4000 Düsseldorf 4-DIMETHYLAMINO-1-HYDROXYBUTANE-1,1-DIPHOSPHONIC ACID, THEIR WATER-SOLUBLE SALTS, PROCESS FOR THEIR PRODUCTION AND THEIR USE
DE3623397A1 (en) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh NEW DIPHOSPHONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Also Published As

Publication number Publication date
WO1993000348A1 (en) 1993-01-07
EP0592488A1 (en) 1994-04-20
AU2150792A (en) 1993-01-25
CA2112250A1 (en) 1993-01-07
PT100624B (en) 1999-07-30
ITFI910160A0 (en) 1991-06-26
PT100624A (en) 1993-10-29
IT1247034B (en) 1994-12-12
JPH06508833A (en) 1994-10-06
MX9203205A (en) 1994-06-30

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950622