IT8723218A0 - Derivati purinici ad azione farmacologica. - Google Patents

Derivati purinici ad azione farmacologica.

Info

Publication number
IT8723218A0
IT8723218A0 IT8723218A IT2321887A IT8723218A0 IT 8723218 A0 IT8723218 A0 IT 8723218A0 IT 8723218 A IT8723218 A IT 8723218A IT 2321887 A IT2321887 A IT 2321887A IT 8723218 A0 IT8723218 A0 IT 8723218A0
Authority
IT
Italy
Prior art keywords
pharmacological action
purine derivatives
purine
derivatives
pharmacological
Prior art date
Application number
IT8723218A
Other languages
English (en)
Other versions
IT1223604B (it
Inventor
Paolo Cornaglia Ferraris
Riccardo Stradi
Original Assignee
Co Pharma Corp Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Co Pharma Corp Srl filed Critical Co Pharma Corp Srl
Priority to IT23218/87A priority Critical patent/IT1223604B/it
Publication of IT8723218A0 publication Critical patent/IT8723218A0/it
Priority to DE8989902205T priority patent/DE3879191T2/de
Priority to PCT/EP1988/001194 priority patent/WO1989005818A1/en
Priority to US07/397,457 priority patent/US5110798A/en
Priority to AT89902205T priority patent/ATE86630T1/de
Priority to JP1502061A priority patent/JP2868560B2/ja
Priority to EP89902205A priority patent/EP0346460B1/en
Priority to AU30528/89A priority patent/AU3052889A/en
Application granted granted Critical
Publication of IT1223604B publication Critical patent/IT1223604B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT23218/87A 1987-12-24 1987-12-24 Derivati purinici ad azione farmacologica IT1223604B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT23218/87A IT1223604B (it) 1987-12-24 1987-12-24 Derivati purinici ad azione farmacologica
DE8989902205T DE3879191T2 (de) 1987-12-24 1988-12-22 Purin-derivate mit pharmakologischer wirksamkeit.
PCT/EP1988/001194 WO1989005818A1 (en) 1987-12-24 1988-12-22 Purine derivatives having pharmacological action
US07/397,457 US5110798A (en) 1987-12-24 1988-12-22 Purine derivatives having pharmacological action
AT89902205T ATE86630T1 (de) 1987-12-24 1988-12-22 Purin-derivate mit pharmakologischer wirksamkeit.
JP1502061A JP2868560B2 (ja) 1987-12-24 1988-12-22 医薬作用を有するプリン誘導体
EP89902205A EP0346460B1 (en) 1987-12-24 1988-12-22 Purine derivatives having pharmacological action
AU30528/89A AU3052889A (en) 1987-12-24 1988-12-22 Purine derivatives having pharmacological action

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23218/87A IT1223604B (it) 1987-12-24 1987-12-24 Derivati purinici ad azione farmacologica

Publications (2)

Publication Number Publication Date
IT8723218A0 true IT8723218A0 (it) 1987-12-24
IT1223604B IT1223604B (it) 1990-09-29

Family

ID=11205008

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23218/87A IT1223604B (it) 1987-12-24 1987-12-24 Derivati purinici ad azione farmacologica

Country Status (8)

Country Link
US (1) US5110798A (it)
EP (1) EP0346460B1 (it)
JP (1) JP2868560B2 (it)
AT (1) ATE86630T1 (it)
AU (1) AU3052889A (it)
DE (1) DE3879191T2 (it)
IT (1) IT1223604B (it)
WO (1) WO1989005818A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1241452B (it) * 1990-06-28 1994-01-17 Sigma Tau Ind Farmaceuti Derivati oligopeptidici dell'ipoxantina dotati di attivita' immunomodulante e composizioni farmaceutiche che li contengono
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
FR2753707B1 (fr) * 1996-09-23 1998-12-11 Complexes nucleopeptidiques, compositions cosmetologiques et pharmaceutiques les contenant et utilisations
EP4308170A1 (en) 2021-03-18 2024-01-24 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5754157A (en) * 1980-09-19 1982-03-31 Nippon Kayaku Co Ltd L-argininal derivative and its preparation
AU564576B2 (en) * 1981-09-24 1987-08-20 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Purine derivatives
DE3141923A1 (de) * 1981-10-22 1983-05-05 Kunz, Horst, Prof. Dr., 6500 Mainz 2(2-pyridyl)ethoxycarbonyl- und 2-(4-pyridyl)ethxycarbonyl-verbindungen und deren pyridiniumsalze
US4387049A (en) * 1982-02-22 1983-06-07 Smithkline Beckman Corporation Adamantyl containing peptides
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.

Also Published As

Publication number Publication date
DE3879191T2 (de) 1993-06-17
US5110798A (en) 1992-05-05
AU3052889A (en) 1989-07-19
IT1223604B (it) 1990-09-29
JP2868560B2 (ja) 1999-03-10
JPH02503006A (ja) 1990-09-20
EP0346460A1 (en) 1989-12-20
WO1989005818A1 (en) 1989-06-29
EP0346460B1 (en) 1993-03-10
DE3879191D1 (de) 1993-04-15
ATE86630T1 (de) 1993-03-15

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19931230