IT8349222A0 - Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica - Google Patents
Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepiletticaInfo
- Publication number
- IT8349222A0 IT8349222A0 IT8349222A IT4922283A IT8349222A0 IT 8349222 A0 IT8349222 A0 IT 8349222A0 IT 8349222 A IT8349222 A IT 8349222A IT 4922283 A IT4922283 A IT 4922283A IT 8349222 A0 IT8349222 A0 IT 8349222A0
- Authority
- IT
- Italy
- Prior art keywords
- benzylamino
- acylamino
- pyridine
- derivatives
- amino
- Prior art date
Links
- 230000003556 anti-epileptic effect Effects 0.000 title 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3239790 | 1982-10-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8349222A0 true IT8349222A0 (it) | 1983-10-26 |
IT1171879B IT1171879B (it) | 1987-06-10 |
Family
ID=6176726
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT49223/83A IT1171880B (it) | 1982-10-27 | 1983-10-26 | Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica e procedimento per la loro produzione |
IT49222/83A IT1171879B (it) | 1982-10-27 | 1983-10-26 | Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT49223/83A IT1171880B (it) | 1982-10-27 | 1983-10-26 | Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica e procedimento per la loro produzione |
Country Status (8)
Country | Link |
---|---|
US (1) | US4554281A (it) |
EP (1) | EP0110091B1 (it) |
JP (2) | JPS5995270A (it) |
AT (1) | ATE25078T1 (it) |
AU (1) | AU561450B2 (it) |
DE (1) | DE3369315D1 (it) |
ES (1) | ES8406440A1 (it) |
IT (2) | IT1171880B (it) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3665538D1 (en) * | 1985-01-23 | 1989-10-19 | Asta Pharma Ag | Synergistic combination of flupirtin and non-steroidal anti-phlogistics |
NO860825L (no) * | 1985-03-23 | 1986-09-24 | Degussa | Fremgangsmaate til fremstilling av 2-amino-3-nitro-6-(4-fluor-benzylamino)-pyridin samt 2-amino-3-karbetoksyamino-6-(4-fluor-benzylamino)-pyridin. |
DE4327516A1 (de) * | 1993-08-17 | 1995-02-23 | Asta Medica Ag | Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin |
US20040191314A1 (en) * | 1994-04-28 | 2004-09-30 | Frank Jao | Antiepileptic dosage form and process for protecting antiepileptic drug |
ZA953078B (en) * | 1994-04-28 | 1996-01-05 | Alza Corp | Effective therapy for epilepsies |
DE19835918A1 (de) * | 1998-08-07 | 2000-02-10 | Dresden Arzneimittel | Neue antikonvulsiv wirkende 4-Amino-1-aryl-pyridin-2-one und Verfahren zu deren Herstellung |
US20050089559A1 (en) * | 2003-10-23 | 2005-04-28 | Istvan Szelenyi | Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
JP2008523139A (ja) * | 2004-12-14 | 2008-07-03 | アストラゼネカ・アクチエボラーグ | 置換アミノピリジン類及びその使用 |
US7960436B2 (en) * | 2006-06-05 | 2011-06-14 | Valeant Pharmaceuticals International | Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators |
US8993593B2 (en) * | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
MX2009002002A (es) * | 2006-08-23 | 2009-07-22 | Valeant Pharmaceuticals Int | Derivados de 4-(n-azacicloalquil) anilidas como moduladores de canal de potasio. |
US8722929B2 (en) * | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
MX2009005652A (es) * | 2006-11-28 | 2009-08-07 | Valeant Pharmaceuticals Int | Analogos 1,4 diamino biciclicos de retigabina como moduladores de canales de potasio. |
US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
US8563566B2 (en) | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
JP2009037141A (ja) | 2007-08-03 | 2009-02-19 | Ricoh Co Ltd | 画像形成装置の管理装置及び管理システム |
US7786146B2 (en) * | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
WO2009074594A1 (en) * | 2007-12-11 | 2009-06-18 | Neurosearch A/S | Novel 2-ethyl-methyl-amino-3-amido-6-amino-pyridine derivatives useful as potassium channel activators |
JP2011506390A (ja) * | 2007-12-11 | 2011-03-03 | ノイロサーチ アクティーゼルスカブ | カリウムチャネル活性化因子として有用な、新規の2−ピロリジニル−3−アミド−6−アミノ−ピリジン誘導体 |
US20110003865A1 (en) * | 2007-12-11 | 2011-01-06 | Carsten Jessen | Novel 2-diethylamino-3-amido-6-amino-pyridine derivatives useful as potassium channel activators |
WO2009074591A1 (en) * | 2007-12-11 | 2009-06-18 | Neurosearch A/S | Novel 2-dimethylamino-3-amido-6-amino-pyridine derivatives useful as potassium channel activators |
CN102351786A (zh) * | 2011-11-01 | 2012-02-15 | 东南大学 | 一种氟吡汀丙二酸盐及其制备方法 |
US11369593B2 (en) | 2017-07-14 | 2022-06-28 | Texas Tech University System | Functionalized pyridine carbamates with enhanced neuroprotective activity |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670523A1 (de) * | 1966-05-12 | 1970-12-03 | Degussa | Verfahren zur Herstellung neuer substituierter Aminopyridine |
BE764362R (en) * | 1966-05-12 | 1971-09-16 | Degussa | Subst amino pyridienes production |
JPS5541411B2 (it) * | 1973-04-28 | 1980-10-24 |
-
1983
- 1983-10-18 DE DE8383110360T patent/DE3369315D1/de not_active Expired
- 1983-10-18 EP EP83110360A patent/EP0110091B1/de not_active Expired
- 1983-10-18 AT AT83110360T patent/ATE25078T1/de active
- 1983-10-25 JP JP58198412A patent/JPS5995270A/ja active Pending
- 1983-10-25 JP JP58198411A patent/JPS5995269A/ja active Granted
- 1983-10-26 IT IT49223/83A patent/IT1171880B/it active
- 1983-10-26 AU AU20582/83A patent/AU561450B2/en not_active Ceased
- 1983-10-26 ES ES526765A patent/ES8406440A1/es not_active Expired
- 1983-10-26 IT IT49222/83A patent/IT1171879B/it active
- 1983-10-27 US US06/545,930 patent/US4554281A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
IT1171879B (it) | 1987-06-10 |
ATE25078T1 (de) | 1987-02-15 |
JPH0144170B2 (it) | 1989-09-26 |
JPS5995270A (ja) | 1984-06-01 |
IT1171880B (it) | 1987-06-10 |
DE3369315D1 (en) | 1987-02-26 |
ES526765A0 (es) | 1984-07-01 |
EP0110091A1 (de) | 1984-06-13 |
AU561450B2 (en) | 1987-05-07 |
IT8349223A0 (it) | 1983-10-26 |
ES8406440A1 (es) | 1984-07-01 |
US4554281A (en) | 1985-11-19 |
AU2058283A (en) | 1984-05-03 |
JPS5995269A (ja) | 1984-06-01 |
EP0110091B1 (de) | 1987-01-21 |
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