IT8024013A0 - Fosfodiesteri di nucleosidi-corticosteroidi citotossici. - Google Patents

Fosfodiesteri di nucleosidi-corticosteroidi citotossici.

Info

Publication number
IT8024013A0
IT8024013A0 IT8024013A IT2401380A IT8024013A0 IT 8024013 A0 IT8024013 A0 IT 8024013A0 IT 8024013 A IT8024013 A IT 8024013A IT 2401380 A IT2401380 A IT 2401380A IT 8024013 A0 IT8024013 A0 IT 8024013A0
Authority
IT
Italy
Prior art keywords
phosphodiesters
nucleosides
corticosteroids
cytotoxic
cytotoxic corticosteroids
Prior art date
Application number
IT8024013A
Other languages
English (en)
Other versions
IT1132532B (it
Inventor
Chung I Hong
Charles R West
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of IT8024013A0 publication Critical patent/IT8024013A0/it
Application granted granted Critical
Publication of IT1132532B publication Critical patent/IT1132532B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT24013/80A 1979-08-06 1980-08-05 Fosfodiesteri di nucleosidi-corticosteroidi citotossici IT1132532B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/063,753 US4283394A (en) 1979-08-06 1979-08-06 Cytotoxic nucleoside-corticosteroid phosphodiesters

Publications (2)

Publication Number Publication Date
IT8024013A0 true IT8024013A0 (it) 1980-08-05
IT1132532B IT1132532B (it) 1986-07-02

Family

ID=22051267

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24013/80A IT1132532B (it) 1979-08-06 1980-08-05 Fosfodiesteri di nucleosidi-corticosteroidi citotossici

Country Status (5)

Country Link
US (1) US4283394A (it)
EP (1) EP0033341A1 (it)
CA (1) CA1145742A (it)
IT (1) IT1132532B (it)
WO (1) WO1981000410A1 (it)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR880000094B1 (ko) * 1984-12-07 1988-02-23 보령제약 주식회사 뉴클레오시드 유도체의 제조방법
US6448392B1 (en) * 1985-03-06 2002-09-10 Chimerix, Inc. Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
FR2641537A1 (fr) * 1989-01-09 1990-07-13 Centre Nat Rech Scient Phosphates d'oxysteryle, synthese et utilisation comme agent pharmaceutique
US4958013A (en) * 1989-06-06 1990-09-18 Northwestern University Cholesteryl modified oligonucleotides
DE4026265A1 (de) * 1990-08-20 1992-02-27 Boehringer Mannheim Gmbh Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
US5563257A (en) * 1990-08-20 1996-10-08 Boehringer Mannheim Gmbh Phospholipid derivatives of nucleosides
DE19602757A1 (de) * 1996-01-26 1997-07-31 Boehringer Mannheim Gmbh Feste Instant-Release-Darreichungsformen und Verfahren zu ihrer Herstellung
US20040121014A1 (en) * 1999-03-22 2004-06-24 Control Delivery Systems, Inc. Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6217895B1 (en) 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US20040208910A1 (en) * 2000-04-26 2004-10-21 Control Delivery Systems, Inc. Sustained release device and method for ocular delivery of adrenergic agents
US20040115268A1 (en) * 2000-04-26 2004-06-17 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
US20040175410A1 (en) * 2000-04-26 2004-09-09 Control Delivery Systems, Inc. Sustained release device and method for ocular delivery of carbonic anhydrase inhibitors
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US8871241B2 (en) 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
US20050233667A1 (en) * 2004-04-16 2005-10-20 Tamko Roofing Products, Inc. System and method for manufacturing polymer mat with reduced capacity spinning pumps
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
JP4827626B2 (ja) * 2006-06-14 2011-11-30 キヤノン株式会社 被制御機器、遠隔制御システムおよび遠隔制御システムの制御方法、プログラム
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
WO2011079232A1 (en) * 2009-12-23 2011-06-30 Psivida Us, Inc. Sustained release delivery devices
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US11103460B2 (en) 2017-08-07 2021-08-31 Board Of Regents, The University Of Texas System Fabrication methods for nanodelivery systems for long term controlled delivery of active pharmaceutical ingredients

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3325474A (en) * 1964-10-06 1967-06-13 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
DE2237377A1 (de) * 1972-07-29 1974-02-14 Hoechst Ag Verfahren zur herstellung von cardenolid-3-eckige klammer auf 2'-desoxyglykosiden eckige klammer zu
JPS51118817A (en) * 1975-04-08 1976-10-19 Nippon Shinyaku Co Ltd A process for preparing absorbable steroid glycoside pharmaceutical

Also Published As

Publication number Publication date
IT1132532B (it) 1986-07-02
CA1145742A (en) 1983-05-03
US4283394A (en) 1981-08-11
WO1981000410A1 (en) 1981-02-19
EP0033341A1 (en) 1981-08-12

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