IT1132532B - Fosfodiesteri di nucleosidi-corticosteroidi citotossici - Google Patents
Fosfodiesteri di nucleosidi-corticosteroidi citotossiciInfo
- Publication number
- IT1132532B IT1132532B IT24013/80A IT2401380A IT1132532B IT 1132532 B IT1132532 B IT 1132532B IT 24013/80 A IT24013/80 A IT 24013/80A IT 2401380 A IT2401380 A IT 2401380A IT 1132532 B IT1132532 B IT 1132532B
- Authority
- IT
- Italy
- Prior art keywords
- corticosteroids
- cytotoxic nucleosides
- nucleosides
- cytotoxic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/063,753 US4283394A (en) | 1979-08-06 | 1979-08-06 | Cytotoxic nucleoside-corticosteroid phosphodiesters |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8024013A0 IT8024013A0 (it) | 1980-08-05 |
IT1132532B true IT1132532B (it) | 1986-07-02 |
Family
ID=22051267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT24013/80A IT1132532B (it) | 1979-08-06 | 1980-08-05 | Fosfodiesteri di nucleosidi-corticosteroidi citotossici |
Country Status (5)
Country | Link |
---|---|
US (1) | US4283394A (it) |
EP (1) | EP0033341A1 (it) |
CA (1) | CA1145742A (it) |
IT (1) | IT1132532B (it) |
WO (1) | WO1981000410A1 (it) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR880000094B1 (ko) * | 1984-12-07 | 1988-02-23 | 보령제약 주식회사 | 뉴클레오시드 유도체의 제조방법 |
US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
US6448392B1 (en) * | 1985-03-06 | 2002-09-10 | Chimerix, Inc. | Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use |
US6252060B1 (en) | 1988-07-07 | 2001-06-26 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
US6599887B2 (en) | 1988-07-07 | 2003-07-29 | Chimerix, Inc. | Methods of treating viral infections using antiviral liponucleotides |
US5817638A (en) * | 1988-07-07 | 1998-10-06 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
FR2641537A1 (fr) * | 1989-01-09 | 1990-07-13 | Centre Nat Rech Scient | Phosphates d'oxysteryle, synthese et utilisation comme agent pharmaceutique |
US4958013A (en) * | 1989-06-06 | 1990-09-18 | Northwestern University | Cholesteryl modified oligonucleotides |
US5563257A (en) * | 1990-08-20 | 1996-10-08 | Boehringer Mannheim Gmbh | Phospholipid derivatives of nucleosides |
DE4026265A1 (de) * | 1990-08-20 | 1992-02-27 | Boehringer Mannheim Gmbh | Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel |
DE19602757A1 (de) * | 1996-01-26 | 1997-07-31 | Boehringer Mannheim Gmbh | Feste Instant-Release-Darreichungsformen und Verfahren zu ihrer Herstellung |
US20040121014A1 (en) * | 1999-03-22 | 2004-06-24 | Control Delivery Systems, Inc. | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
US6217895B1 (en) * | 1999-03-22 | 2001-04-17 | Control Delivery Systems | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
US20040115268A1 (en) * | 2000-04-26 | 2004-06-17 | Control Delivery Systems, Inc. | Systemic delivery of antiviral agents |
US20040208910A1 (en) * | 2000-04-26 | 2004-10-21 | Control Delivery Systems, Inc. | Sustained release device and method for ocular delivery of adrenergic agents |
US20040175410A1 (en) * | 2000-04-26 | 2004-09-09 | Control Delivery Systems, Inc. | Sustained release device and method for ocular delivery of carbonic anhydrase inhibitors |
US6375972B1 (en) * | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
US20030129186A1 (en) | 2001-07-25 | 2003-07-10 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
US8871241B2 (en) * | 2002-05-07 | 2014-10-28 | Psivida Us, Inc. | Injectable sustained release delivery devices |
US20050233667A1 (en) * | 2004-04-16 | 2005-10-20 | Tamko Roofing Products, Inc. | System and method for manufacturing polymer mat with reduced capacity spinning pumps |
SI1889198T1 (sl) | 2005-04-28 | 2015-02-27 | Proteus Digital Health, Inc. | Farma-informacijski sistem |
JP4827626B2 (ja) * | 2006-06-14 | 2011-11-30 | キヤノン株式会社 | 被制御機器、遠隔制御システムおよび遠隔制御システムの制御方法、プログラム |
EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
DK2398500T3 (da) | 2009-02-20 | 2019-05-13 | 2 Bbb Medicines B V | Glutathion-baseret lægemiddelafgivelsessystem |
ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
CN102740830A (zh) * | 2009-12-23 | 2012-10-17 | 普西维达公司 | 缓释递送装置 |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
US11103460B2 (en) | 2017-08-07 | 2021-08-31 | Board Of Regents, The University Of Texas System | Fabrication methods for nanodelivery systems for long term controlled delivery of active pharmaceutical ingredients |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3325474A (en) * | 1964-10-06 | 1967-06-13 | Merck & Co Inc | Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds |
DE2237377A1 (de) * | 1972-07-29 | 1974-02-14 | Hoechst Ag | Verfahren zur herstellung von cardenolid-3-eckige klammer auf 2'-desoxyglykosiden eckige klammer zu |
JPS51118817A (en) * | 1975-04-08 | 1976-10-19 | Nippon Shinyaku Co Ltd | A process for preparing absorbable steroid glycoside pharmaceutical |
-
1979
- 1979-08-06 US US06/063,753 patent/US4283394A/en not_active Expired - Lifetime
-
1980
- 1980-07-28 WO PCT/US1980/000938 patent/WO1981000410A1/en unknown
- 1980-08-05 IT IT24013/80A patent/IT1132532B/it active
- 1980-08-05 CA CA000357621A patent/CA1145742A/en not_active Expired
-
1981
- 1981-02-24 EP EP80901639A patent/EP0033341A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA1145742A (en) | 1983-05-03 |
IT8024013A0 (it) | 1980-08-05 |
WO1981000410A1 (en) | 1981-02-19 |
US4283394A (en) | 1981-08-11 |
EP0033341A1 (en) | 1981-08-12 |
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