IT8022677A0 - Sostanze dotate di attivita'antispastica vasale e procedimenti per la loro preparazione. - Google Patents
Sostanze dotate di attivita'antispastica vasale e procedimenti per la loro preparazione.Info
- Publication number
- IT8022677A0 IT8022677A0 IT8022677A IT2267780A IT8022677A0 IT 8022677 A0 IT8022677 A0 IT 8022677A0 IT 8022677 A IT8022677 A IT 8022677A IT 2267780 A IT2267780 A IT 2267780A IT 8022677 A0 IT8022677 A0 IT 8022677A0
- Authority
- IT
- Italy
- Prior art keywords
- vasal
- procedures
- substances
- preparation
- antispastic activity
- Prior art date
Links
- UOTMYNBWXDUBNX-UHFFFAOYSA-N 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinolin-2-ium;chloride Chemical compound Cl.C1=C(OC)C(OC)=CC=C1CC1=NC=CC2=CC(OC)=C(OC)C=C12 UOTMYNBWXDUBNX-UHFFFAOYSA-N 0.000 title 1
- 230000001663 anti-spastic effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22677/80A IT1150959B (it) | 1980-06-10 | 1980-06-10 | Sostanze datate di attivita' antispastica vasale e procedimenti per la loro preparazione |
EP81200613A EP0041757B1 (en) | 1980-06-10 | 1981-06-04 | Ethylendiamine derivatives, preparation thereof, pharmaceutical compositions containing same and intermediates for their preparation |
DE8181200613T DE3167047D1 (en) | 1980-06-10 | 1981-06-04 | Ethylendiamine derivatives, preparation thereof, pharmaceutical compositions containing same and intermediates for their preparation |
AT81200613T ATE10187T1 (de) | 1980-06-10 | 1981-06-04 | Aethylendiaminderivate, ihre herstellung, sie enthaltende pharmazeutische zusammensetzungen sowie zwischenprodukte zu ihrer herstellung. |
US06/270,808 US4381305A (en) | 1980-06-10 | 1981-06-05 | Ethylenediamine derivatives and pharmaceutical compositions containing same |
JP8832381A JPS5728031A (en) | 1980-06-10 | 1981-06-10 | Ethylenediamine derivative and medicinal composition as effective component thereof |
US06/446,671 US4467094A (en) | 1980-06-10 | 1982-12-03 | Precursors to ethylenediamine derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22677/80A IT1150959B (it) | 1980-06-10 | 1980-06-10 | Sostanze datate di attivita' antispastica vasale e procedimenti per la loro preparazione |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8022677A0 true IT8022677A0 (it) | 1980-06-10 |
IT1150959B IT1150959B (it) | 1986-12-17 |
Family
ID=11199159
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22677/80A IT1150959B (it) | 1980-06-10 | 1980-06-10 | Sostanze datate di attivita' antispastica vasale e procedimenti per la loro preparazione |
Country Status (6)
Country | Link |
---|---|
US (2) | US4381305A (it) |
EP (1) | EP0041757B1 (it) |
JP (1) | JPS5728031A (it) |
AT (1) | ATE10187T1 (it) |
DE (1) | DE3167047D1 (it) |
IT (1) | IT1150959B (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4588735A (en) * | 1983-02-28 | 1986-05-13 | Chevron Research Company | Fungicidal (trihalophenoxy or trihalophenthio) alkylaminoalkyl pyridines and pyrroles |
ES8502099A1 (es) * | 1983-08-02 | 1984-12-16 | Espanola Farma Therapeut | Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina. |
US4720586A (en) * | 1983-12-06 | 1988-01-19 | Fisons, Plc | Substituted 3,4-dihydroxy-phenylethylamino compounds |
JPH064584B2 (ja) * | 1984-02-29 | 1994-01-19 | 沢井製薬株式会社 | 新規アニリド誘導体 |
US4855497A (en) * | 1985-04-02 | 1989-08-08 | Chugai Seiyaku Kabushiki Kaisha | Novel diamine derivatives |
IT1205124B (it) * | 1987-06-05 | 1989-03-15 | Simens Soteta Italiana Medicin | Composto attivo nella terapia carciovascolare |
TW438591B (en) * | 1995-06-07 | 2001-06-07 | Arris Pharm Corp | Reversible cysteine protease inhibitors |
US7511077B2 (en) * | 2005-02-09 | 2009-03-31 | Neuromed Pharmaceuticals Ltd. | Diamine calcium channel blockers |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD76234A (it) * | ||||
US2946793A (en) * | 1957-09-25 | 1960-07-26 | Abbott Lab | Carbinol amines |
FR1511398A (fr) * | 1966-02-16 | 1968-01-26 | Takeda Chemical Industries Ltd | Procédé de préparation de nouveaux dérivés de picoline |
US3876702A (en) * | 1968-04-26 | 1975-04-08 | Rudolf Theodor Petersen | N,n-bis-(diphenylalkyl)-alkylendiamine and their salts |
HU164883B (it) * | 1972-04-24 | 1974-05-28 | ||
US3970663A (en) * | 1973-05-02 | 1976-07-20 | Science Union Et Cie, Societe Francaise De Recherche Medical | Certain amino-nicotinamide derivatives |
-
1980
- 1980-06-10 IT IT22677/80A patent/IT1150959B/it active
-
1981
- 1981-06-04 DE DE8181200613T patent/DE3167047D1/de not_active Expired
- 1981-06-04 EP EP81200613A patent/EP0041757B1/en not_active Expired
- 1981-06-04 AT AT81200613T patent/ATE10187T1/de not_active IP Right Cessation
- 1981-06-05 US US06/270,808 patent/US4381305A/en not_active Expired - Lifetime
- 1981-06-10 JP JP8832381A patent/JPS5728031A/ja active Granted
-
1982
- 1982-12-03 US US06/446,671 patent/US4467094A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH0154341B2 (it) | 1989-11-17 |
EP0041757B1 (en) | 1984-11-07 |
US4381305A (en) | 1983-04-26 |
US4467094A (en) | 1984-08-21 |
DE3167047D1 (en) | 1984-12-13 |
EP0041757A1 (en) | 1981-12-16 |
JPS5728031A (en) | 1982-02-15 |
IT1150959B (it) | 1986-12-17 |
ATE10187T1 (de) | 1984-11-15 |
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