IT7850591A0 - Derivati della pepstatina ad azione inibitrice della renina e relativo procedimento di preparazione - Google Patents
Derivati della pepstatina ad azione inibitrice della renina e relativo procedimento di preparazioneInfo
- Publication number
- IT7850591A0 IT7850591A0 IT7850591A IT5059178A IT7850591A0 IT 7850591 A0 IT7850591 A0 IT 7850591A0 IT 7850591 A IT7850591 A IT 7850591A IT 5059178 A IT5059178 A IT 5059178A IT 7850591 A0 IT7850591 A0 IT 7850591A0
- Authority
- IT
- Italy
- Prior art keywords
- preparation procedure
- inhibiting action
- related preparation
- renin inhibiting
- pepstatin derivatives
- Prior art date
Links
- 102100028255 Renin Human genes 0.000 title 1
- 108090000783 Renin Proteins 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- FAXGPCHRFPCXOO-LXTPJMTPSA-N pepstatin A Chemical class OC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C FAXGPCHRFPCXOO-LXTPJMTPSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/86—Renin inhibitors
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7724093A FR2399409A1 (fr) | 1977-08-04 | 1977-08-04 | Nouveaux derives de la pepstatine, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7850591A0 true IT7850591A0 (it) | 1978-08-03 |
| IT1107964B IT1107964B (it) | 1985-12-02 |
Family
ID=9194246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT50591/78A IT1107964B (it) | 1977-08-04 | 1978-08-03 | Derivati della pepstatina ad azione inibitrice della renina e relativo procedimento di preparazione |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4185096A (it) |
| JP (1) | JPS5448710A (it) |
| BE (1) | BE869261A (it) |
| CH (1) | CH634041A5 (it) |
| DE (1) | DE2834001A1 (it) |
| FR (1) | FR2399409A1 (it) |
| GB (1) | GB2003481B (it) |
| IT (1) | IT1107964B (it) |
| NL (1) | NL7808140A (it) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4384994A (en) * | 1981-10-08 | 1983-05-24 | Merck & Co., Inc. | Renin inhibitory peptides |
| US4478826A (en) * | 1981-10-08 | 1984-10-23 | Merck & Co., Inc. | Renin inhibitory peptides |
| CA1258748A (en) | 1981-10-08 | 1989-08-22 | Daniel F. Veber | Renin inhibitory peptides |
| US4479941A (en) * | 1981-12-10 | 1984-10-30 | Merck & Co., Inc. | Renin inhibitory peptides having PHE13 delection |
| US4650661A (en) * | 1982-09-15 | 1987-03-17 | Aktiebolaget Hassle | Enzyme inhibitors |
| US4485099A (en) * | 1983-06-15 | 1984-11-27 | Merck & Co., Inc. | Renin inhibitors containing a C-terminal amide cycle |
| US4661473A (en) * | 1984-03-27 | 1987-04-28 | Merck & Co., Inc. | Renin inhibitors containing peptide isosteres |
| US4663310A (en) * | 1984-04-04 | 1987-05-05 | Merck & Co., Inc. | Renin inhibitors containing 2-substituted statine |
| US4906613A (en) * | 1985-11-05 | 1990-03-06 | Schering Corporation | Antiglaucoma compositions and methods |
| US4743584A (en) * | 1986-10-07 | 1988-05-10 | Merck & Co., Inc. | C-terminal amide cyclic renin inhibitors containing peptide isosteres |
| US5688770A (en) * | 1989-12-14 | 1997-11-18 | Schering Corporation | Antiglaucoma compositions and methods |
| WO1994024150A2 (en) * | 1993-04-21 | 1994-10-27 | Nzym Inc. | Pepstatin derivatives for treatment, prevention and detection of infections |
| US5833946A (en) * | 1995-06-06 | 1998-11-10 | Bayer Corporation | Dissemination of fungal infections: animal model and method of prophylaxis |
| EP2113510A1 (en) | 2008-04-30 | 2009-11-04 | Freie Universität Berlin | Pepstatin A derivatives |
| FR3002736B1 (fr) * | 2013-03-04 | 2015-06-26 | Virbac | Composition orale nutritionnelle et medicamenteuse a usage veterinaire |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3867364A (en) * | 1968-11-21 | 1975-02-18 | Microbial Chem Res Found | Process for the synthesis of leupeptins and their analogues |
| US3840516A (en) * | 1969-06-13 | 1974-10-08 | Microbial Chem Res Found | Biologically active substance,pepstatin and production processes thereof |
| JPS5022116B1 (it) * | 1970-04-28 | 1975-07-28 | ||
| US3869347A (en) * | 1971-03-26 | 1975-03-04 | Microbial Chem Res Found | Process for the production of new pepstatins having anti-pepsin activity |
-
1977
- 1977-08-04 FR FR7724093A patent/FR2399409A1/fr active Granted
-
1978
- 1978-07-25 BE BE189497A patent/BE869261A/xx not_active IP Right Cessation
- 1978-07-31 US US05/929,562 patent/US4185096A/en not_active Expired - Lifetime
- 1978-08-01 GB GB7831780A patent/GB2003481B/en not_active Expired
- 1978-08-02 NL NL787808140A patent/NL7808140A/xx not_active Application Discontinuation
- 1978-08-03 DE DE19782834001 patent/DE2834001A1/de not_active Withdrawn
- 1978-08-03 IT IT50591/78A patent/IT1107964B/it active
- 1978-08-03 CH CH829178A patent/CH634041A5/fr not_active IP Right Cessation
- 1978-08-04 JP JP9468678A patent/JPS5448710A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US4185096A (en) | 1980-01-22 |
| DE2834001A1 (de) | 1979-02-22 |
| FR2399409A1 (fr) | 1979-03-02 |
| GB2003481A (en) | 1979-03-14 |
| IT1107964B (it) | 1985-12-02 |
| JPS5448710A (en) | 1979-04-17 |
| NL7808140A (nl) | 1979-02-06 |
| CH634041A5 (fr) | 1983-01-14 |
| GB2003481B (en) | 1982-02-10 |
| FR2399409B1 (it) | 1980-09-19 |
| BE869261A (fr) | 1979-01-25 |
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